Alexandre Arcaro

10.9k total citations · 1 hit paper
51 papers, 3.9k citations indexed

About

Alexandre Arcaro is a scholar working on Molecular Biology, Cell Biology and Pathology and Forensic Medicine. According to data from OpenAlex, Alexandre Arcaro has authored 51 papers receiving a total of 3.9k indexed citations (citations by other indexed papers that have themselves been cited), including 40 papers in Molecular Biology, 10 papers in Cell Biology and 8 papers in Pathology and Forensic Medicine. Recurrent topics in Alexandre Arcaro's work include PI3K/AKT/mTOR signaling in cancer (23 papers), Protein Kinase Regulation and GTPase Signaling (11 papers) and Cancer Mechanisms and Therapy (6 papers). Alexandre Arcaro is often cited by papers focused on PI3K/AKT/mTOR signaling in cancer (23 papers), Protein Kinase Regulation and GTPase Signaling (11 papers) and Cancer Mechanisms and Therapy (6 papers). Alexandre Arcaro collaborates with scholars based in Switzerland, United Kingdom and United States. Alexandre Arcaro's co-authors include Matthias P. Wymann, Ana Guerreiro Stücklin, Michael D. Waterfield, Michael J. Seckl, Kathrin T. Doepfner, Marin Marinov, Teresa D. Tetley, Barbara Fischer, Michael A. Grotzer and Jan Domin and has published in prestigious journals such as Journal of Biological Chemistry, The Journal of Experimental Medicine and The EMBO Journal.

In The Last Decade

Alexandre Arcaro

51 papers receiving 3.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Wortmannin is a potent phosphatidylinositol 3-kinase inhibitor: the role of phosphatidylinositol 3,4,5-trisphosphate in neutrophil responses

1993 1.0k citations Alexandre Arcaro et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Alexandre Arcaro Switzerland	31	2.6k	761	667	659	351	51	3.9k
Tilman Brummer Germany	35	2.9k 1.1×	897 1.2×	468 0.7×	1.2k 1.8×	265 0.8×	98	4.3k
Martijn F.B.G. Gebbink Netherlands	34	2.4k 0.9×	770 1.0×	412 0.6×	424 0.6×	321 0.9×	60	4.0k
Yasuhisa Fukui Japan	35	3.4k 1.3×	459 0.6×	1.1k 1.7×	801 1.2×	230 0.7×	85	4.5k
Keith Dredge United States	30	2.2k 0.9×	613 0.8×	917 1.4×	983 1.5×	359 1.0×	55	3.7k
Ana C. Carrera Spain	42	3.3k 1.3×	1.6k 2.2×	672 1.0×	1.1k 1.6×	453 1.3×	96	5.4k
François Houle Canada	26	3.0k 1.2×	641 0.8×	794 1.2×	570 0.9×	162 0.5×	38	4.1k
Karen A. Cadwallader United Kingdom	21	2.6k 1.0×	568 0.7×	792 1.2×	781 1.2×	114 0.3×	28	3.7k
Deborah H. Anderson Canada	24	2.8k 1.1×	641 0.8×	780 1.2×	732 1.1×	213 0.6×	59	3.9k
Mark Manfredi United States	24	2.2k 0.9×	540 0.7×	1.0k 1.5×	1.3k 2.0×	204 0.6×	57	3.7k
W. Stratford May United States	31	2.7k 1.0×	1.1k 1.5×	573 0.9×	813 1.2×	694 2.0×	42	4.9k

Countries citing papers authored by Alexandre Arcaro

Since Specialization

Citations

This map shows the geographic impact of Alexandre Arcaro's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Alexandre Arcaro with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Alexandre Arcaro more than expected).

Fields of papers citing papers by Alexandre Arcaro

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Alexandre Arcaro. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Alexandre Arcaro. The network helps show where Alexandre Arcaro may publish in the future.

Co-authorship network of co-authors of Alexandre Arcaro

This figure shows the co-authorship network connecting the top 25 collaborators of Alexandre Arcaro. A scholar is included among the top collaborators of Alexandre Arcaro based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Alexandre Arcaro. Alexandre Arcaro is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Liu, Yang, Martin Pejchinοvski, Xueqi Wang, et al.. (2018). Dual mTOR/PI3K inhibition limits PI3K-dependent pathways activated upon mTOR inhibition in autosomal dominant polycystic kidney disease. Scientific Reports. 8(1). 5584–5584. 23 indexed citations

Arcaro, Alexandre. (2015). Development of Drugs Targeting the PI3K Signalling Pathway in Leukaemias and Lymphomas. 49–58. 1 indexed citations

Fiaschetti, Giulio, Christina I. Schroeder, Deborah Castelletti, et al.. (2014). NOTCH ligands JAG1 and JAG2 as critical pro-survival factors in childhood medulloblastoma. Acta Neuropathologica Communications. 2(1). 39–39. 30 indexed citations

Liu, Yang, Andres Käch, Urs Ziegler, et al.. (2013). The Role of Phospholipase D in Modulating the MTOR Signaling Pathway in Polycystic Kidney Disease. PLoS ONE. 8(8). e73173–e73173. 18 indexed citations

Fischer, Barbara, Francesco Mauri, Jens Sobek, et al.. (2012). Targeting the Phosphoinositide 3-Kinase p110-α Isoform Impairs Cell Proliferation, Survival, and Tumor Growth in Small Cell Lung Cancer. Clinical Cancer Research. 19(1). 96–105. 25 indexed citations

Fiaschetti, Giulio, Deborah Castelletti, Stefan Zoller, et al.. (2011). Bone morphogenetic protein-7 is a MYC target with prosurvival functions in childhood medulloblastoma. Oncogene. 30(25). 2823–2835. 21 indexed citations

Fiaschetti, Giulio, et al.. (2011). Quassinoids: From Traditional Drugs to New Cancer Therapeutics. Current Medicinal Chemistry. 18(3). 316–328. 67 indexed citations

Castelletti, Deborah, Giulio Fiaschetti, Valeria Di Dato, et al.. (2010). The Quassinoid Derivative NBT-272 Targets Both the AKT and ERK Signaling Pathways in Embryonal Tumors. Molecular Cancer Therapeutics. 9(12). 3145–3157. 11 indexed citations

Shalaby, Tarek, André O. von Bueren, Giulio Fiaschetti, et al.. (2010). Disabling c-Myc in Childhood Medulloblastoma and Atypical Teratoid/Rhabdoid Tumor Cells by the Potent G-Quadruplex Interactive Agent S2T1-6OTD. Molecular Cancer Therapeutics. 9(1). 167–179. 39 indexed citations

10.

Laurentiis, Angela De, Olivier E. Pardo, Andrea Palamidessi, et al.. (2010). The catalytic class IA PI3K isoforms play divergent roles in breast cancer cell migration. Cellular Signalling. 23(3). 529–541. 6 indexed citations

11.

Marinov, Marin, Algirdas Ziogas, Olivier E. Pardo, et al.. (2009). AKT/mTOR Pathway Activation and BCL-2 Family Proteins Modulate the Sensitivity of Human Small Cell Lung Cancer Cells to RAD001. Clinical Cancer Research. 15(4). 1277–1287. 79 indexed citations

12.

Schramm, Alexander, Kathrin T. Doepfner, Tarek Shalaby, et al.. (2008). Targeting the Phosphoinositide 3-Kinase Isoform p110δ Impairs Growth and Survival in Neuroblastoma Cells. Clinical Cancer Research. 14(4). 1172–1181. 60 indexed citations

13.

Thorley, Andrew J., Julia Gorelik, Michael J. Seckl, et al.. (2008). Immortalization of Human Alveolar Epithelial Cells to Investigate Nanoparticle Uptake. American Journal of Respiratory Cell and Molecular Biology. 39(5). 591–597. 105 indexed citations

14.

Stücklin, Ana Guerreiro, Sarah Fattet, Barbara Fischer, et al.. (2008). Targeting the PI3K p110α Isoform Inhibits Medulloblastoma Proliferation, Chemoresistance, and Migration. Clinical Cancer Research. 14(21). 6761–6769. 67 indexed citations

15.

Arcaro, Alexandre & Ana Guerreiro Stücklin. (2007). The Phosphoinositide 3-Kinase Pathway in Human Cancer: Genetic Alterations and Therapeutic Implications. Current Genomics. 8(5). 271–306. 209 indexed citations

16.

Pardo, Olivier E., Alexandre Arcaro, Giovanni Salerno, et al.. (2001). Novel cross talk between MEK and S6K2 in FGF-2 induced proliferation of SCLC cells. Oncogene. 20(52). 7658–7667. 64 indexed citations

17.

Arcaro, Alexandre, Claude Grégoire, Nicole Boucheron, et al.. (2000). Essential Role of CD8 Palmitoylation in CD8 Coreceptor Function. The Journal of Immunology. 165(4). 2068–2076. 156 indexed citations

18.

Arcaro, Alexandre, Marketa Zvelebil, Christian Wallasch, et al.. (2000). Class II Phosphoinositide 3-Kinases Are Downstream Targets of Activated Polypeptide Growth Factor Receptors. Molecular and Cellular Biology. 20(11). 3817–3830. 136 indexed citations

19.

Brown, Richard A., Jan Domin, Alexandre Arcaro, Michael D. Waterfield, & Peter R. Shepherd. (1999). Insulin Activates the α Isoform of Class II Phosphoinositide 3-Kinase. Journal of Biological Chemistry. 274(21). 14529–14532. 114 indexed citations

20.

Surdo, Paola Lo, Matthew J. Bottomley, Alexandre Arcaro, et al.. (1999). Structural and Biochemical Evaluation of the Interaction of the Phosphatidylinositol 3-Kinase p85α Src Homology 2 Domains with Phosphoinositides and Inositol Polyphosphates. Journal of Biological Chemistry. 274(22). 15678–15685. 15 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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