Marleen Dekker

2.8k citations

28 papers · 2.3k indexed · 1 hit paper · h-index 16

Co-authors: Hein te Riele Niels de Wind Miroslav Radman Anton Berns Martin van der Valk Jan‐Hermen Dannenberg P. de Boer Sandra S. de Vries
Topics: Genetic factors in colorectal cancer (15 papers)Cancer Genomics and Diagnostics (10 papers)DNA Repair Mechanisms (8 papers)
Cited by: Pathology and Forensic Medicine Cancer Research Oncology
Journals: Nature Science Cell
Partner nations: Netherlands United Kingdom France

In The Last Decade

Marleen Dekker

25 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

1995 679 citations Niels de Wind, Marleen Dekker et al. Cell profile →

Peers

Countries citing papers authored by Marleen Dekker

Since Specialization

Citations

This map shows the geographic impact of Marleen Dekker's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Marleen Dekker with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Marleen Dekker more than expected).

Fields of papers citing papers by Marleen Dekker

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Marleen Dekker. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Marleen Dekker. The network helps show where Marleen Dekker may publish in the future.

Co-authorship network of co-authors of Marleen Dekker

This figure shows the co-authorship network connecting the top 25 collaborators of Marleen Dekker. A scholar is included among the top collaborators of Marleen Dekker based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Marleen Dekker. Marleen Dekker is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Zincore, an atypical coregulator, binds zinc finger transcription factors to control gene expression 2025 ·Science ·D. W. Bianchi,(unknown),(unknown),Guizela Huelsz‐Prince,(unknown),Marleen Dekker,Alexander Fish,Abdelghani Mazouzi,Lona J. Kroese,Simon Linder,Miguel Hernández-Quiles,Michiel Vermeulen,Patrick H. N. Celie,Paul Krimpenfort,Ji‐Ying Song,Wilbert Zwart,Lodewyk F.A. Wessels,(unknown),Anastassis Perrakis,Thijn R. Brummelkamp	0
2	Unexpected moves: a conformational change in MutSα enables high-affinity DNA mismatch binding 2023 ·Nucleic Acids Research ·(unknown),Wietske Pieters,Alexander Fish,A. Manuel Liaci,(unknown),Emily Rayner,(unknown),Lisa Drost,Marleen Dekker,(unknown),(unknown),(unknown),(unknown),Hendrikus J. Dubbink,(unknown),Niels de Wind,Friedrich Förster,Hein te Riele,Titia K. Sixma	9
3	Identification of an alternative triglyceride biosynthesis pathway 2023 ·Nature ·Gian‐Luca McLelland,(unknown),(unknown),(unknown),(unknown),(unknown),Marleen Dekker,Lisa G. van den Hengel,Rahmen Bin Ali,Hans Janssen,Ji‐Ying Song,Paul Krimpenfort,Tim van Zutphen,Johan W. Jonker,Thijn R. Brummelkamp	42
4	Extensive trimming of short single-stranded DNA oligonucleotides during replication-coupled gene editing in mammalian cells 2020 ·PLoS Genetics ·(unknown),(unknown),Wietske Pieters,Marleen Dekker,Hein te Riele	2
5	Three-step site-directed mutagenesis screen identifies pathogenic MLH1 variants associated with Lynch syndrome 2019 ·Journal of Medical Genetics ·(unknown),Marleen Dekker,(unknown),Wietske Pieters,(unknown),Senno Verhoef,Robert M.W. Hofstra,Hein te Riele	7
6	Loss of p53 suppresses replication-stress-induced DNA breakage in G1/S checkpoint deficient cells 2018 ·eLife ·Bente Benedict,(unknown),Marleen Dekker,(unknown),Aslι Küçükosmanoğlu,Wietske Pieters,(unknown),Josephine C. Dorsman,Eva Petermann,Floris Foijer,Hein te Riele	39
7	Suspected Lynch syndrome associated MSH6 variants: A functional assay to determine their pathogenicity 2017 ·PLoS Genetics ·(unknown),Anne Goverde,(unknown),Marleen Dekker,Marco J. Bruno,Fred H. Menko,Arjen R. Mensenkamp,Manon C.W. Spaander,Anja Wagner,Robert M.W. Hofstra,Hein te Riele	15
8	RB Family Tumor Suppressor Activity May Not Relate to Active Silencing of E2F Target Genes 2014 ·Cancer Research ·Tinke L. Vormer,(unknown),Marleen Dekker,(unknown),(unknown),(unknown),Shalin H. Naik,Ji‐Ying Song,Jan‐Hermen Dannenberg,Jacob B. Hansen,Hein te Riele	13
9	Temozolomide Increases the Number of Mismatch Repair–Deficient Intestinal Crypts and Accelerates Tumorigenesis in a Mouse Model of Lynch Syndrome 2014 ·Gastroenterology ·(unknown),(unknown),Bastiaan van Gerwen,(unknown),(unknown),(unknown),Ji‐Ying Song,(unknown),Marleen Dekker,Hein te Riele	23
10	Transient suppression of MLH1 allows effective single-nucleotide substitution by single-stranded DNA oligonucleotides 2011 ·Mutation research. Fundamental and molecular mechanisms of mutagenesis ·Marleen Dekker,(unknown),Marieke Aarts,Robert G. Dekker,Conny Brouwers,Oliver T. Wiebenga,Niels de Wind,(unknown),Roberto Tonelli,Hein te Riele	11
11	Gene Modification in Embryonic Stem Cells by Single-Stranded DNA Oligonucleotides 2009 ·Methods in molecular biology ·Marieke Aarts,Marleen Dekker,Rob J. Dekker,(unknown),(unknown),(unknown),Hein te Riele	10
12	Generation of Double-Knockout Embryonic Stem Cells 2009 ·Methods in molecular biology ·(unknown),Marleen Dekker,Hein te Riele	1
13	Generation of a mouse mutant by oligonucleotide-mediated gene modification in ES cells 2006 ·Nucleic Acids Research ·Marieke Aarts,Marleen Dekker,(unknown),(unknown),Hein te Riele	44
14	Effective oligonucleotide-mediated gene disruption in ES cells lacking the mismatch repair protein MSH3 2006 ·Gene Therapy ·Marleen Dekker,Conny Brouwers,Marieke Aarts,Jaco van der Torre,(unknown),(unknown),Hein te Riele	31
15	Tissue-specific tumor suppressor activity of retinoblastoma gene homologs p107 and p130 2004 ·Genes & Development ·Jan‐Hermen Dannenberg,Leontine Schuijff,Marleen Dekker,Martin van der Valk,Hein te Riele	113
16	Mouse MutS-like protein Msh5 is required for proper chromosome synapsis in male and female meiosis 1999 ·Genes & Development ·Sandra S. de Vries,Esther B. Baart,Marleen Dekker,(unknown),Dirk G. de Rooij,P. de Boer,Hein te Riele	282
17	HNPCC-like cancer predisposition in mice through simultaneous loss of Msh3 and Msh6 mismatch-repair protein functions 1999 ·Nature Genetics ·Niels de Wind,Marleen Dekker,Nanna Claij,L.A.M. Jansen,(unknown),Miroslav Radman,Greg Riggins,Martin van der Valk,(unknown),Hein te Riele	173
18	p107 is a suppressor of retinoblastoma development in pRb-deficient mice 1998 ·Genes & Development ·Els C. Robanus-Maandag,Marleen Dekker,Martin van der Valk,M.L. Carrozza,Jean‐Claude Jeanny,Jan‐Hermen Dannenberg,Anton Berns,Hein te Riele	245
19	Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancerbreakdown → 1995 ·Cell ·Niels de Wind,Marleen Dekker,Anton Berns,Miroslav Radman,Hein te Riele	679
20	Binding of human immunodeficiency virus type-1 to follicular dendritic cells in vitro is complement dependent 1993 ·The Journal of Immunology ·P. Joling,Leendert J. Bakker,Jos A. G. van Strijp,Timo Meerloo,Loek de Graaf,Marleen Dekker,Jaap Goudsmit,J. Verhoef,Henk‐Jan Schuurman	84

About Marleen Dekker

Marleen Dekker is a scholar working on Pathology and Forensic Medicine, Cancer Research and Ophthalmology, having authored 28 papers that have together received 2.3k indexed citations. Recurring topics across this work include Genetic factors in colorectal cancer (15 papers), Cancer Genomics and Diagnostics (10 papers) and DNA Repair Mechanisms (8 papers). The work is most often cited by research in Pathology and Forensic Medicine (936 citations), Cancer Research (619 citations) and Oncology (644 citations). Marleen Dekker has collaborated with scholars based in Netherlands, United Kingdom and France. Frequent co-authors include Hein te Riele, Niels de Wind, Miroslav Radman, Anton Berns, Martin van der Valk, Jan‐Hermen Dannenberg, P. de Boer, Sandra S. de Vries, Dirk G. de Rooij and Esther B. Baart. Their work appears in journals such as Nature, Science and Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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