Yi Zhang

83.4k total citations · 34 hit papers
420 papers, 60.2k citations indexed

About

Yi Zhang is a scholar working on Molecular Biology, Genetics and Cancer Research. According to data from OpenAlex, Yi Zhang has authored 420 papers receiving a total of 60.2k indexed citations (citations by other indexed papers that have themselves been cited), including 331 papers in Molecular Biology, 62 papers in Genetics and 42 papers in Cancer Research. Recurrent topics in Yi Zhang's work include Epigenetics and DNA Methylation (178 papers), Cancer-related gene regulation (95 papers) and Genomics and Chromatin Dynamics (68 papers). Yi Zhang is often cited by papers focused on Epigenetics and DNA Methylation (178 papers), Cancer-related gene regulation (95 papers) and Genomics and Chromatin Dynamics (68 papers). Yi Zhang collaborates with scholars based in United States, China and Japan. Yi Zhang's co-authors include Paul Tempst, Ru Cao, Hediye Erdjument‐Bromage, Danny Reinberg, Hengbin Wang, Cyrus Martin, Azusa Inoue, Robert J. Klose, Susan C. Wu and Li Shen and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Yi Zhang

399 papers receiving 59.4k citations

Hit Papers

Role of Histone H3 Lysine... 1998 2026 2007 2016 2002 2011 2013 2010 2005 500 1000 1.5k 2.0k 2.5k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing
    2002 2.9k citations Ru Cao, Liangjun Wang et al. Science profile →
  2. Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine
    2011 2.6k citations Shinsuke Ito, Li Shen et al. Science profile →
  3. Double Nicking by RNA-Guided CRISPR Cas9 for Enhanced Genome Editing Specificity
    2013 2.6k citations Yi Zhang et al. profile →
  4. Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
    2010 2.0k citations Shinsuke Ito, Ana C. D’Alessio et al. Nature profile →
  5. Histone demethylation by a family of JmjC domain-containing proteins
    2005 1.7k citations Jia Fang, Hediye Erdjument‐Bromage et al. Nature profile →
  6. The diverse functions of histone lysine methylation
    2005 1.6k citations Yi Zhang et al. profile →
  7. Role of histone H2A ubiquitination in Polycomb silencing
    2004 1.3k citations Hengbin Wang, Liangjun Wang et al. Nature profile →
  8. TET enzymes, TDG and the dynamics of DNA demethylation
    2013 1.2k citations Yi Zhang et al. Nature profile →
  9. Transcription regulation by histone methylation: interplay between different covalent modifications of the core histone tails
    2001 1.2k citations Yi Zhang et al. Genes & Development profile →
  10. TET-mediated active DNA demethylation: mechanism, function and beyond
    2017 1.1k citations Yi Zhang et al. profile →
  11. JmjC-domain-containing proteins and histone demethylation
    2006 997 citations Yi Zhang et al. profile →
  12. Role of Histone H3 Lysine 27 Methylation in X Inactivation
    2003 945 citations Jia Fang, Ru Cao et al. Science profile →
  13. Analysis of the NuRD subunits reveals a histone deacetylase core complex and a connection with DNA methylation
    1999 891 citations Yi Zhang, Paul Tempst et al. Genes & Development profile →
  14. Active DNA demethylation: many roads lead to Rome
    2010 827 citations Susan C. Wu, Yi Zhang profile →
  15. Reversing DNA Methylation: Mechanisms, Genomics, and Biological Functions
    2014 806 citations Yi Zhang et al. profile →
  16. The functions of E(Z)/EZH2-mediated methylation of lysine 27 in histone H3
    2004 728 citations Ru Cao, Yi Zhang profile →
  17. MBD2 is a transcriptional repressor belonging to the MeCP1 histone deacetylase complex
    1999 718 citations Yi Zhang, Hediye Erdjument‐Bromage et al. profile →
  18. DNA Methylation in Mammals
    2014 685 citations Yi Zhang et al. profile →
  19. The Dermatomyositis-Specific Autoantigen Mi2 Is a Component of a Complex Containing Histone Deacetylase and Nucleosome Remodeling Activities
    1998 683 citations Yi Zhang et al. profile →
  20. Role of Bmi-1 and Ring1A in H2A Ubiquitylation and Hox Gene Silencing
    2005 676 citations Ru Cao, Yi Zhang et al. profile →
  21. Regulation of histone methylation by demethylimination and demethylation
    2007 661 citations Yi Zhang et al. profile →
  22. Methylation of H3-Lysine 79 Is Mediated by a New Family of HMTases without a SET Domain
    2002 650 citations Hengbin Wang, Hediye Erdjument‐Bromage et al. profile →
  23. JHDM2A, a JmjC-Containing H3K9 Demethylase, Facilitates Transcription Activation by Androgen Receptor
    2006 641 citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  24. SUZ12 Is Required for Both the Histone Methyltransferase Activity and the Silencing Function of the EED-EZH2 Complex
    2004 638 citations Ru Cao, Yi Zhang profile →
  25. Methylation of Histone H4 at Arginine 3 Facilitating Transcriptional Activation by Nuclear Hormone Receptor
    2001 627 citations Hengbin Wang, Hediye Erdjument‐Bromage et al. Science profile →
  26. hDOT1L Links Histone Methylation to Leukemogenesis
    2005 622 citations Yuki Okada, Yi Zhang et al. profile →
  27. Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27
    2003 512 citations Jinrong Min, Yi Zhang et al. Genes & Development profile →
  28. The transcriptional repressor JHDM3A demethylates trimethyl histone H3 lysine 9 and lysine 36
    2006 505 citations Hediye Erdjument‐Bromage, Paul Tempst et al. Nature profile →
  29. Dual functions of Tet1 in transcriptional regulation in mouse embryonic stem cells
    2011 501 citations Hao Wu, Ana C. D’Alessio et al. Nature profile →
  30. Single-Cell RNA-Seq Reveals Hypothalamic Cell Diversity
    2017 406 citations Yi Zhang et al. profile →
  31. Local triple-combination therapy results in tumour regression and prevents recurrence in a colon cancer model
    2016 401 citations Yi Zhang et al. profile →
  32. Embryonic Development following Somatic Cell Nuclear Transfer Impeded by Persisting Histone Methylation
    2014 356 citations Li Shen, Yi Zhang et al. profile →
  33. The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
    2007 336 citations Hediye Erdjument‐Bromage, Paul Tempst et al. profile →
  34. Maternal H3K27me3 controls DNA methylation-independent imprinting
    2017 323 citations Yi Zhang et al. Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Yi Zhang United States 110 52.9k 9.3k 5.6k 3.6k 3.5k 420 60.2k
Tony Kouzarides United Kingdom 94 44.9k 0.8× 6.5k 0.7× 5.5k 1.0× 3.9k 1.1× 7.0k 2.0× 176 53.9k
Andrew P. Feinberg United States 92 45.0k 0.9× 15.5k 1.7× 6.8k 1.2× 5.0k 1.4× 5.9k 1.7× 235 62.2k
Adrian Bird United Kingdom 100 51.3k 1.0× 21.6k 2.3× 4.2k 0.7× 4.6k 1.3× 2.5k 0.7× 232 61.8k
C. David Allis United States 143 77.5k 1.5× 9.7k 1.0× 5.1k 0.9× 8.8k 2.5× 5.7k 1.6× 344 87.9k
Peter A. Jones United States 112 48.9k 0.9× 8.9k 1.0× 10.9k 1.9× 1.9k 0.5× 8.3k 2.4× 352 61.5k
Thomas Jenuwein Austria 84 36.9k 0.7× 5.9k 0.6× 3.2k 0.6× 5.6k 1.6× 2.6k 0.7× 124 41.3k
James A. Thomson United States 87 50.7k 1.0× 6.0k 0.6× 3.5k 0.6× 1.5k 0.4× 2.5k 0.7× 253 60.2k
Stephen W. Scherer Canada 97 22.5k 0.4× 18.5k 2.0× 3.1k 0.6× 4.0k 1.1× 2.0k 0.6× 534 40.0k
Stylianos E. Antonarakis Switzerland 102 21.9k 0.4× 13.3k 1.4× 3.4k 0.6× 2.7k 0.8× 1.9k 0.6× 602 40.8k
Alexander Meissner United States 75 31.1k 0.6× 7.0k 0.8× 4.1k 0.7× 1.0k 0.3× 1.2k 0.4× 174 36.0k

Countries citing papers authored by Yi Zhang

Since Specialization
Citations

This map shows the geographic impact of Yi Zhang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Yi Zhang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Yi Zhang more than expected).

Fields of papers citing papers by Yi Zhang

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Yi Zhang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Yi Zhang. The network helps show where Yi Zhang may publish in the future.

Co-authorship network of co-authors of Yi Zhang

This figure shows the co-authorship network connecting the top 25 collaborators of Yi Zhang. A scholar is included among the top collaborators of Yi Zhang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Yi Zhang. Yi Zhang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
2.
Zhou, Chengjie, Meng Wang, Chunxia Zhang, & Yi Zhang. (2025). The transcription factor GABPA is a master regulator of naive pluripotency. Nature Cell Biology. 27(1). 48–58. 5 indexed citations
3.
Jia, Kun‐Peng, Jun Fang, Xuan Zhu, et al.. (2023). CD95 promotes stemness of colorectal cancer cells by lncRNA MALAT1. Life Sciences. 338. 122394–122394. 5 indexed citations
4.
Wang, Meng, Zhiyuan Chen, & Yi Zhang. (2022). CBP /p300 and HDAC activities regulate H3K27 acetylation dynamics and zygotic genome activation in mouse preimplantation embryos. The EMBO Journal. 41(22). e112012–e112012. 84 indexed citations
5.
Zhang, Yi, et al.. (2022). Medical gloves modified by a one-minute spraying process with blood-repellent, antibacterial and wound-healing abilities. Biomaterials Science. 10(4). 939–946. 5 indexed citations
6.
Zhai, Zhiwei, et al.. (2021). Crosstalk in oxygen homeostasis networks: SKN-1/NRF inhibits the HIF-1 hypoxia-inducible factor in Caenorhabditis elegans. PLoS ONE. 16(7). e0249103–e0249103. 4 indexed citations
7.
Chen, Zhiyuan, Zhenfei Xie, & Yi Zhang. (2021). DPPA2 and DPPA4 are dispensable for mouse zygotic genome activation and pre-implantation development. Development. 148(24). 24 indexed citations
8.
Sun, Chao, Min Li, Ying Feng, et al.. (2020). MDM2-P53 Signaling Pathway-Mediated Upregulation of CDC20 Promotes Progression of Human Diffuse Large B-Cell Lymphoma. SHILAP Revista de lepidopterología. 1 indexed citations
9.
10.
Zhang, Xiuwu, Caroline Hadley, Isabel L. Jackson, et al.. (2016). Hypo-CpG methylation controls PTEN expression and cell apoptosis in irradiated lung. Free Radical Research. 50(8). 875–886. 15 indexed citations
11.
Yang, Min, Yi Zhang, Weiguo Wang, et al.. (2015). TNM Staging of Pancreatic Neuroendocrine Tumors. Medicine. 94(12). e660–e660. 33 indexed citations
12.
Li, Xiang, Wei Wei, Qiongyi Zhao, et al.. (2014). Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation. Proceedings of the National Academy of Sciences. 111(19). 7120–7125. 142 indexed citations
13.
He, Yanghua, Ying Yu, Yuan Zhang, et al.. (2012). Genome-Wide Bovine H3K27me3 Modifications and the Regulatory Effects on Genes Expressions in Peripheral Blood Lymphocytes. PLoS ONE. 7(6). e39094–e39094. 15 indexed citations
14.
Ito, Shinsuke, Li Shen, Qing Dai, et al.. (2011). Tet Proteins Can Convert 5-Methylcytosine to 5-Formylcytosine and 5-Carboxylcytosine. Science. 333(6047). 1300–1303. 2619 indexed citations breakdown →
15.
Smid, Marcel, Anieta M. Sieuwerts, Stefan Sleijfer, et al.. (2010). Patterns and incidence of chromosomal instability and their prognostic relevance in breast cancer subtypes. Breast Cancer Research and Treatment. 128(1). 23–30. 77 indexed citations
16.
Wu, Hao, Volkan Coskun, Jifang Tao, et al.. (2010). Dnmt3a-Dependent Nonpromoter DNA Methylation Facilitates Transcription of Neurogenic Genes. Science. 329(5990). 444–448. 466 indexed citations
17.
Okada, Yuki, Kazuo Yamagata, Kwonho Hong, Teruhiko Wakayama, & Yi Zhang. (2010). A role for the elongator complex in zygotic paternal genome demethylation. Nature. 463(7280). 554–558. 209 indexed citations
18.
Huang, Ying, Jia Fang, Mark T. Bedford, Yi Zhang, & Rui-Ming Xu. (2006). Recognition of Histone H3 Lysine-4 Methylation by the Double Tudor Domain of JMJD2A. Science. 312(5774). 748–751. 362 indexed citations
19.
Min, Jinrong, Yi Zhang, & Rui-Ming Xu. (2003). Structural basis for specific binding of Polycomb chromodomain to histone H3 methylated at Lys 27. Genes & Development. 17(15). 1823–1828. 512 indexed citations breakdown →
20.
Cao, Ru, Liangjun Wang, Hengbin Wang, et al.. (2002). Role of Histone H3 Lysine 27 Methylation in Polycomb-Group Silencing. Science. 298(5595). 1039–1043. 2927 indexed citations breakdown →

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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