Patrick Hwu

42.0k total citations · 7 hit papers
220 papers, 15.8k citations indexed

About

Patrick Hwu is a scholar working on Oncology, Immunology and Molecular Biology. According to data from OpenAlex, Patrick Hwu has authored 220 papers receiving a total of 15.8k indexed citations (citations by other indexed papers that have themselves been cited), including 148 papers in Oncology, 133 papers in Immunology and 74 papers in Molecular Biology. Recurrent topics in Patrick Hwu's work include Immunotherapy and Immune Responses (111 papers), Cancer Immunotherapy and Biomarkers (80 papers) and CAR-T cell therapy research (76 papers). Patrick Hwu is often cited by papers focused on Immunotherapy and Immune Responses (111 papers), Cancer Immunotherapy and Biomarkers (80 papers) and CAR-T cell therapy research (76 papers). Patrick Hwu collaborates with scholars based in United States, Australia and China. Patrick Hwu's co-authors include Nicholas P. Restifo, Steven A. Rosenberg, Willem W. Overwijk, Réjean Lapointe, Laszlo Radvanyi, Gregory Lizée, Yanyan Lou, Suzanne L. Topalian, John R. Wunderlich and Douglas J. Schwartzentruber and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Patrick Hwu

216 papers receiving 15.6k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Cancer Regression and Autoimmunity in Patients After Clonal Repopulation with Antitumor Lymphocytes

2002 2.2k citations Patrick Hwu, Nicholas P. Restifo et al. profile →
PD-L1 Expression in Triple-Negative Breast Cancer

2014 1.1k citations Elizabeth A. Mittendorf, Anne V. Philips et al. Cancer Immunology Research profile →
Loss of IFN-γ Pathway Genes in Tumor Cells as a Mechanism of Resistance to Anti-CTLA-4 Therapy

2016 913 citations Jason Roszik, Chantale Bernatchez et al. profile →
T Helper 17 Cells Promote Cytotoxic T Cell Activation in Tumor Immunity

2009 618 citations Natalia Martín‐Orozco, Patrick Hwu et al. profile →
Indoleamine 2,3-Dioxygenase Production by Human Dendritic Cells Results in the Inhibition of T Cell Proliferation

2000 617 citations Patrick Hwu, Réjean Lapointe et al. profile →
STING activation of tumor endothelial cells initiates spontaneous and therapeutic antitumor immunity

2015 447 citations Patrick Hwu et al. Proceedings of the National Academy of Sciences profile →
Epithelial–Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma

2016 349 citations Yanyan Lou, Lixia Diao et al. Clinical Cancer Research profile →

Peers

Countries citing papers authored by Patrick Hwu

Since Specialization

Citations

This map shows the geographic impact of Patrick Hwu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Patrick Hwu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Patrick Hwu more than expected).

Fields of papers citing papers by Patrick Hwu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Patrick Hwu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Patrick Hwu. The network helps show where Patrick Hwu may publish in the future.

Co-authorship network of co-authors of Patrick Hwu

This figure shows the co-authorship network connecting the top 25 collaborators of Patrick Hwu. A scholar is included among the top collaborators of Patrick Hwu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Patrick Hwu. Patrick Hwu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Safety and immunogenicity of a third dose of mRNA‐1273 vaccine among cancer patients 2023 ·Cancer Communications ·Anna R. Giuliano, Barbara J. Kuter, Shari Pilon‐Thomas, Junmin Whiting, Qianxing Mo, Brett Leav, Bradley Sirak, Christopher Cubitt, (unknown), (unknown), (unknown), Somedeb Ball, (unknown), Akriti Jain, Patrick Hwu, Jeffrey E. Lancet	6
2	Circulating Tumor Cells and Early Relapse in Node-positive Melanoma 2020 ·Clinical Cancer Research ·Anthony Lucci, Carolyn Hall, Sapna P. Patel, (unknown), Jessica B. Bauldry, Richard E. Royal, Mandar Karhade, (unknown), Jennifer A. Wargo, Isabella C. Glitza, Michael K. Wong, Rodabe N. Amaria, Hussein A. Tawbi, Adi Diab, Michael A. Davies, Jeffrey E. Gershenwald, Jeffrey E. Lee, Patrick Hwu, Merrick I. Ross	52
3	First-in-Class, First-in-Human Study Evaluating LV305, a Dendritic-Cell Tropic Lentiviral Vector, in Sarcoma and Other Solid Tumors Expressing NY-ESO-1 2019 ·Clinical Cancer Research ·Neeta Somaiah, Matthew S. Block, Joseph W. Kim, Geoffrey I. Shapiro, T. Khanh, Patrick Hwu, Joseph P. Eder, Robin L. Jones, Hailing Lu, Jan H. ter Meulen, Chet Bohac, Michael Chen, Frank J. Hsu, Sacha Gnjatic, Seth M. Pollack	71
4	Anti-OX40 Antibody Directly Enhances The Function of Tumor-Reactive CD8+ T Cells and Synergizes with PI3Kβ Inhibition in PTEN Loss Melanoma 2019 ·Clinical Cancer Research ·Weiyi Peng, Leila J. Williams, Chunyu Xu, Brenda Melendez, Jodi A. McKenzie, Yuan Chen, (unknown), Kui Shin Voo, Rina M. Mbofung, Sara Elizabeth Leahey, Jian Wang, Gregory Lizée, Hussein A. Tawbi, Michael A. Davies, Axel Hoos, James Smothers, Roopa Srinivasan, Elaine Paul, Niranjan Yanamandra, Patrick Hwu	33
5	T-cell Homing Therapy for Reducing Regulatory T Cells and Preserving Effector T-cell Function in Large Solid Tumors 2018 ·Clinical Cancer Research ·Jiemiao Hu, Chuang Sun, Chantale Bernatchez, Xueqing Xia, Patrick Hwu, Gianpietro Dotti, Shulin Li	62
6	Radiation Followed by OX40 Stimulation Drives Local and Abscopal Antitumor Effects in an Anti–PD1-Resistant Lung Tumor Model 2018 ·Clinical Cancer Research ·Sharareh Niknam, Hampartsoum B. Barsoumian, Jonathan E. Schoenhals, (unknown), Niranjan Yanamandra, Mauricio S. Caetano, Ailin Li, Ahmed Younes, Alexandra P. Cadena, Taylor R. Cushman, Joe Y. Chang, Q.N. Nguyen, Daniel R. Gomez, Adi Diab, John V. Heymach, Patrick Hwu, María Angélica Cortez, James W. Welsh	46
7	Multifaceted Role of BTLA in the Control of CD8+ T-cell Fate after Antigen Encounter 2017 ·Clinical Cancer Research ·Krit Ritthipichai, Cara Haymaker, (unknown), (unknown), Xiaohui Yi, Minying Zhang, (unknown), Luis M. Vence, Jason Roszik, Yared Hailemichael, Willem W. Overwijk, Navin Varadarajan, Roza Nurieva, Laszlo Radvanyi, Patrick Hwu, Chantale Bernatchez	54
8	SLC45A2: A Melanoma Antigen with High Tumor Selectivity and Reduced Potential for Autoimmune Toxicity 2017 ·Cancer Immunology Research ·Jungsun Park, Amjad H. Talukder, Seon Ah Lim, Kwanghee Kim, (unknown), Brenda Melendez, Sherille D. Bradley, (unknown), Jahan S. Khalili, Junmei Wang, Caitlin Creasy, (unknown), Scott E. Woodman, Chantale Bernatchez, David H. Hawke, Patrick Hwu, Kyung‐Mi Lee, Jason Roszik, Gregory Lizée, Cassian Yee	24
9	Hypoxia-Driven Mechanism of Vemurafenib Resistance in Melanoma 2016 ·Molecular Cancer Therapeutics ·Yong Qin, Jason Roszik, Chandrani Chattopadhyay, Yuuri Hashimoto, Chengwen Liu, Zachary A. Cooper, Jennifer A. Wargo, Patrick Hwu, Sühendan Ekmekçioğlu, Elizabeth A. Grimm	41
10	Epithelial–Mesenchymal Transition Is Associated with a Distinct Tumor Microenvironment Including Elevation of Inflammatory Signals and Multiple Immune Checkpoints in Lung Adenocarcinoma breakdown → 2016 ·Clinical Cancer Research ·Yanyan Lou, Lixia Diao, Edwin R. Parra, Warren L. Denning, Limo Chen, You Hong Fan, Lauren A. Byers, Jing Wang, Vassiliki A. Papadimitrakopoulou, Carmen Behrens, Jaime Canales Rodriguez, Patrick Hwu, Ignacio I. Wistuba, John V. Heymach, Don L. Gibbons	349
11	IL2 Variant Circumvents ICOS+ Regulatory T-cell Expansion and Promotes NK Cell Activation 2016 ·Cancer Immunology Research ·Geok Choo Sim, Chengwen Liu, Ena Wang, Hui Liu, Caitlin Creasy, Zhimin Dai, Willem W. Overwijk, Jason Roszik, Francesco M. Marincola, Patrick Hwu, (unknown), Laszlo Radvanyi	36
12	BRAFV600E Co-opts a Conserved MHC Class I Internalization Pathway to Diminish Antigen Presentation and CD8+ T-cell Recognition of Melanoma 2015 ·Cancer Immunology Research ·Sherille D. Bradley, Zeming Chen, Brenda Melendez, Amjad H. Talukder, Jahan S. Khalili, Tania Rodríguez-Cruz, Shujuan Liu, Mayra Whittington, Wanleng Deng, Fenge Li, Chantale Bernatchez, Laszlo Radvanyi, Michael A. Davies, Patrick Hwu, Gregory Lizée	124
13	Manipulating the Tumor Microenvironment Ex Vivo for Enhanced Expansion of Tumor-Infiltrating Lymphocytes for Adoptive Cell Therapy 2014 ·Clinical Cancer Research ·Jessica Chacon, Amod A. Sarnaik, Jie Qing Chen, Caitlin Creasy, (unknown), John Robinson, Jeffrey S. Weber, Patrick Hwu, Shari Pilon‐Thomas, Laszlo Radvanyi	48
14	PD-L1 Expression in Triple-Negative Breast Cancer breakdown → 2014 ·Cancer Immunology Research ·Elizabeth A. Mittendorf, Anne V. Philips, Funda Meric‐Bernstam, Na Qiao, Yun Wu, Susan M. Harrington, Xiaoping Su, Ying Wang, Ana M. González-Angulo, Argun Akçakanat, Akhil Chawla, Michael A. Curran, Patrick Hwu, Padmanee Sharma, Jennifer K. Litton, Jeffrey J. Molldrem, Gheath Alatrash	1065
15	Detection and Characterization of a Novel Subset of CD8+CD57+ T Cells in Metastatic Melanoma with an Incompletely Differentiated Phenotype 2012 ·Clinical Cancer Research ·Richard C. Wu, Shujuan Liu, Jessica Chacon, Sheng Wu, Yufeng Li, Pariya Sukhumalchandra, (unknown), Jeffrey J. Molldrem, Patrick Hwu, Hanspeter Pircher, Gregory Lizée, Laszlo Radvanyi	19
16	PD-1 Blockade Enhances T-cell Migration to Tumors by Elevating IFN-γ Inducible Chemokines 2012 ·Cancer Research ·Weiyi Peng, Chengwen Liu, Chunyu Xu, Yanyan Lou, Jieqing Chen, Yan Yang, Hideo Yagita∥, Willem W. Overwijk, Gregory Lizée, Laszlo Radvanyi, Patrick Hwu	340
17	A New Approach to Simultaneously Quantify Both TCR α- and β-Chain Diversity after Adoptive Immunotherapy 2012 ·Clinical Cancer Research ·Minying Zhang, Sourindra N. Maiti, Chantale Bernatchez, Helen Huls, Brian Rabinovich, Richard E. Champlin, Luis M. Vence, Patrick Hwu, Laszlo Radvanyi, Laurence J.N. Cooper	15
18	Melanoma Cells Express ICOS Ligand to Promote the Activation and Expansion of T-Regulatory Cells 2010 ·Cancer Research ·Natalia Martín‐Orozco, Yufeng Li, Yi‐Jun Wang, Shijuan Liu, Patrick Hwu, Yong‐Jun Liu, Chen Dong, Laszlo Radvanyi	109
19	Induction of CD4+ T cell–dependent antitumor immunity by TAT-mediated tumor antigen delivery into dendritic cells 2002 ·Journal of Clinical Investigation ·Helen Y. Wang, Tihui Fu, Gang Wang, Gang Zeng, Donna Perry-Lalley, James C. Yang, Nicholas P. Restifo, Patrick Hwu, Rongfu Wang	78
20	HIV-1 induces phenotypic and functional perturbations of B cells in chronically infected individuals 2001 ·Proceedings of the National Academy of Sciences ·Susan Moir, Angela Malaspina, Kisani M. Ogwaro, Eileen T. Donoghue, Claire W. Hallahan, Linda A. Ehler, Shu-Ying Liu, Joseph W. Adelsberger, Réjean Lapointe, Patrick Hwu, Michael Baseler, Jan M. Orenstein, Tae‐Wook Chun, Jo Ann M. Mican, Anthony S. Fauci	242

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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