Margaret van Heek

3.9k citations

40 papers · 2.7k indexed · 1 hit paper · h-index 21

Endocrine and Autonomic Systems top 0.5%
- Regulation of Appetite and Obesity 11
Nutrition and Dietetics top 1%
- Biochemical Analysis and Sensing Techniques 6
Physiology top 5%
- Adipose Tissue and Metabolism 7
Endocrinology, Diabetes and Metabolism top 5%
Surgery top 5%
- Cholesterol and Lipid Metabolism 13
- Lipoproteins and Cardiovascular Health 6
Organic Chemistry
- Synthesis of β-Lactam Compounds 6
Biochemistry
- Lipid metabolism and biosynthesis 5
Oncology
- Drug Transport and Resistance Mechanisms 4

Co-authors: Douglas S. Compton Harry R. Davis Edmund J. Sybertz Constance Farley Lizbeth Hoos Catherine D. Strader Ahmad Fawzi Joyce Hwa
Cited by: Endocrine and Autonomic Systems Nutrition and Dietetics Physiology
Journals: Journal of Biological Chemistry (1 paper)Journal of Clinical Investigation (1 paper)Diabetes (2 papers)
Partner nations: United States United Kingdom China

In The Last Decade

Margaret van Heek

40 papers receiving 2.6k citations

Hit Papers

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Peers

Countries citing papers authored by Margaret van Heek

Since Specialization

Citations

This map shows the geographic impact of Margaret van Heek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margaret van Heek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margaret van Heek more than expected).

Fields of papers citing papers by Margaret van Heek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margaret van Heek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margaret van Heek. The network helps show where Margaret van Heek may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Margaret van Heek, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Margaret van Heek Line = papers co-authored together Margaret van Heek links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts Diabetes ·Mary Courtney Moore,David E. Kelley,Raul C. Camacho,Peter Zafian,Ye Tian,Songnian Lin,Niels C. Kaarsholm,Ravi P. Nargund,Terri Kelly,Margaret van Heek,Stephen F. Previs,Christopher R. Moyes,Marta S. Smith,Ben Farmer,P. E. V. Williams,Alan D. Cherrington	2018	15
2	Discovery of XEN445: A potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice Bioorganic & Medicinal Chemistry ·Shaoyi Sun,Richard A. Dean,Qi Jia,Alla Zenova,Jing Zhong,Celene Grayson,Clark Xie,Andrea Lindgren,Pritpaul Samra,Luis Sojo,Margaret van Heek,Linus Lin,D. Percival,Jianmin Fu,Michael D. Winther,Zaihui Zhang	2013	10
3	Identification of 2-aminooxazole amides as acyl-CoA: Diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy Bioorganic & Medicinal Chemistry Letters ·Hyunjin M. Kim,Michelle Smith,Jae‐Hun Kim,Mary Ann Caplen,Tin Yau Chan,Brian A. McKittrick,John A. Cook,Margaret van Heek,Jean E. Lachowicz	2013	10
4	Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1) Bioorganic & Medicinal Chemistry Letters ·Yongqi Deng,Zhiwei Yang,Gerald W. Shipps,Sie‐Mun Lo,Robert West,Joyce Hwa,Shuqin Zheng,Constance Farley,Jean E. Lachowicz,Margaret van Heek,Alan Bass,Dinesh P. Sinha,Craig R. Mahon,Mark E. Cartwright	2012	15
5	Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Pauline C. Ting,Joe F. Lee,Nicolas F. Zorn,Hyunjin M. Kim,Robert Aslanian,Mingxiang Lin,Michelle Smith,Scott S. Walker,John A. Cook,Margaret van Heek,Jean E. Lachowicz	2012	8
6	SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist Bioorganic & Medicinal Chemistry Letters ·Xianhai Huang,Jing Su,Ashwin U. Rao,Haiqun Tang,Wei Zhou,Xiaohong Zhu,Xiaohong Chen,Zhidan Liu,Ying Huang,Sylvia J. Degrado,Dong Xiao,Jun Qin,Robert Aslanian,Brian A. McKittrick,Scott Greenfeder,Margaret van Heek,Madhu Chintala,Anandan Palani	2011	12
7	Discovery of novel orally active ureido NPY Y5 receptor antagonists Bioorganic & Medicinal Chemistry Letters ·Guo‐Qing Li,Andrew W. Stamford,Ying Huang,Kuo-Chi Cheng,John A. Cook,Constance Farley,Jun Gao,Lorraine Ghibaudi,William J. Greenlee,M. Guzzi,Margaret van Heek,Joyce Hwa,J.S. Kelly,Deborra Mullins,Eric M. Parker,Sam Wainhaus,Xiaoping Zhang	2007	14
8	Tetrahydroisoquinolines as MCH-R1 antagonists Bioorganic & Medicinal Chemistry Letters ·T.K. Sasikumar,Qiang Li,Wen‐Lian Wu,Duane A. Burnett,William J. Greenlee,Kathleen O’Neill,Brian E. Hawes,Margaret van Heek,M P Graziano	2006	6
9	Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,April Smith‐Torhan,Harry R. Davis	2003	51
10	Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet Brain Research ·Jun Gao,Lorraine Ghibaudi,Margaret van Heek,Joyce Hwa	2002	41
11	Fat Intake Affects Adiposity, Comorbidity Factors, and Energy Metabolism of Sprague‐Dawley Rats Obesity Research ·Lorraine Ghibaudi,John A. Cook,Constance Farley,Margaret van Heek,Joyce Hwa	2002	169
12	Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status European Journal of Pharmacology ·Eric M. Parker,Margaret van Heek,Andrew W. Stamford	2002	64
13	The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys European Journal of Pharmacology ·Margaret van Heek,Douglas S. Compton,Harry R. Davis	2001	109
14	Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,Harry R. Davis	2001	173
15	Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663 British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,Kevin B. Alton,Edmund J. Sybertz,Harry R. Davis	2000	265
16	Cholesteryl Hydroperoxyoctadecadienoate from Oxidized Low Density Lipoprotein Inactivates Platelet-derived Growth Factor Journal of Biological Chemistry ·Margaret van Heek,David Schmitt,Paul Toren,Martha K. Cathcart,Paul E. DiCorleto	1998	20
17	Effect of Chronic Central Administration of Glucagon‐Like Peptide‐1 (7–36) Amide on Food Consumption and Body Weight in Normal and Obese Rats Obesity Research ·Harry R. Davis,Deborra Mullins,Jesse M. Pines,Lizbeth Hoos,Constance F. France,Douglas S. Compton,Michael P. Graziano,Edmund J. Sybertz,Catherine D. Strader,Margaret van Heek	1998	49
18	The Relationship of Tissue Localization, Distribution and Turnover to Feeding After Intraperitoneal¹²⁵I-Leptin Administration toob/obanddb/dbMice Hormone and Metabolic Research ·Margaret van Heek,Donald E. Mullins,Michael D. Wirth,Marco Graziano,Ahmad Fawzi,Douglas S. Compton,Christopher France,Lizbeth Hoos,R Casale,Edmund J. Sybertz,Catherine D. Strader,Hilda M. Davis	1996	45
19	Purification of Milligram Quantities of Human Leptin From RecombinantE. Coli Hormone and Metabolic Research ·Ahmad Fawzi,H. Zhang,Margaret van Heek,Marco Graziano	1996	16
20	The Liptin Haemopoietic Cytokine Fold is Stabilized by an Intrachain Disulfide Bond Hormone and Metabolic Research ·Fernando Rock,S. Altmann,Margaret van Heek,Rob Kastelein,J. Fernando Bazán	1996	46

About Margaret van Heek

Margaret van Heek is a scholar working on Endocrine and Autonomic Systems, Biochemistry and Nutrition and Dietetics, having authored 40 papers that have together received 2.7k indexed citations. Recurring topics across this work include Cholesterol and Lipid Metabolism (13 papers), Regulation of Appetite and Obesity (11 papers), Adipose Tissue and Metabolism (7 papers), Lipoproteins and Cardiovascular Health (6 papers), Synthesis of β-Lactam Compounds (6 papers), Biochemical Analysis and Sensing Techniques (6 papers), Lipid metabolism and biosynthesis (5 papers) and Drug Transport and Resistance Mechanisms (4 papers). The work is most often cited by research in Endocrine and Autonomic Systems (887 citations), Nutrition and Dietetics (621 citations) and Physiology (684 citations). Margaret van Heek has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Douglas S. Compton, Harry R. Davis, Edmund J. Sybertz, Constance Farley, Lizbeth Hoos, Catherine D. Strader, Ahmad Fawzi, Joyce Hwa, John A. Cook and M P Graziano. Their work appears in journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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