Margaret van Heek

3.9k citations

40 papers · 2.7k indexed · 1 hit paper · h-index 21

Surgery top 5%
Endocrine and Autonomic Systems top 0.5%
Physiology top 5%
Nutrition and Dietetics top 1%
Epidemiology top 5%

Co-authors: Douglas S. Compton Harry R. Davis Edmund J. Sybertz Constance Farley Lizbeth Hoos Catherine D. Strader Ahmad Fawzi Joyce Hwa
Topics: Cholesterol and Lipid Metabolism (13 papers)Regulation of Appetite and Obesity (11 papers)Adipose Tissue and Metabolism (7 papers)
Cited by: Endocrine and Autonomic Systems Nutrition and Dietetics Physiology
Journals: Journal of Biological Chemistry Journal of Clinical Investigation Diabetes
Partner nations: United States United Kingdom China

In The Last Decade

Margaret van Heek

40 papers receiving 2.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Diet-induced obese mice develop peripheral, but not central, resistance to leptin.

1997 649 citations Margaret van Heek, Douglas S. Compton et al. profile →

Peers

Countries citing papers authored by Margaret van Heek

Since Specialization

Citations

This map shows the geographic impact of Margaret van Heek's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Margaret van Heek with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Margaret van Heek more than expected).

Fields of papers citing papers by Margaret van Heek

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Margaret van Heek. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Margaret van Heek. The network helps show where Margaret van Heek may publish in the future.

Co-authorship network of co-authors of Margaret van Heek

This figure shows the co-authorship network connecting the top 25 collaborators of Margaret van Heek. A scholar is included among the top collaborators of Margaret van Heek based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Margaret van Heek. Margaret van Heek is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Superior Glycemic Control With a Glucose-Responsive Insulin Analog: Hepatic and Nonhepatic Impacts 2018 ·Diabetes ·Mary Courtney Moore,David E. Kelley,Raul C. Camacho,Peter Zafian,Ye Tian,Songnian Lin,Niels C. Kaarsholm,Ravi P. Nargund,(unknown),Margaret van Heek,Stephen F. Previs,Christopher R. Moyes,Marta S. Smith,Ben Farmer,P. E. V. Williams,Alan D. Cherrington	15
2	Discovery of XEN445: A potent and selective endothelial lipase inhibitor raises plasma HDL-cholesterol concentration in mice 2013 ·Bioorganic & Medicinal Chemistry ·Shaoyi Sun,Richard A. Dean,Qi Jia,(unknown),Jing Zhong,Celene Grayson,(unknown),Andrea Lindgren,(unknown),Luis Sojo,Margaret van Heek,(unknown),D. Percival,Jianmin Fu,Michael D. Winther,Zaihui Zhang	10
3	Identification of 2-aminooxazole amides as acyl-CoA: Diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy 2013 ·Bioorganic & Medicinal Chemistry Letters ·Hyunjin M. Kim,Michelle Smith,Jae‐Hun Kim,Mary Ann Caplen,(unknown),Brian A. McKittrick,John A. Cook,Margaret van Heek,Jean E. Lachowicz	10
4	Discovery of liver-targeted inhibitors of stearoyl-CoA desaturase (SCD1) 2012 ·Bioorganic & Medicinal Chemistry Letters ·Yongqi Deng,Zhiwei Yang,Gerald W. Shipps,(unknown),Robert West,Joyce Hwa,Shuqin Zheng,Constance Farley,Jean E. Lachowicz,Margaret van Heek,Alan Bass,Dinesh P. Sinha,(unknown),Mark E. Cartwright	15
5	Lead optimization of a pyridine-carboxamide series as DGAT-1 inhibitors 2012 ·Bioorganic & Medicinal Chemistry Letters ·Pauline C. Ting,(unknown),Nicolas F. Zorn,Hyunjin M. Kim,Robert Aslanian,Mingxiang Lin,Michelle Smith,Scott S. Walker,John A. Cook,Margaret van Heek,Jean E. Lachowicz	8
6	SAR studies of C2 ethers of 2H-pyrano[2,3-d]pyrimidine-2,4,7(1H,3H)-triones as nicotinic acid receptor (NAR) agonist 2011 ·Bioorganic & Medicinal Chemistry Letters ·Xianhai Huang,Jing Su,(unknown),(unknown),Wei Zhou,Xiaohong Zhu,Xiaohong Chen,Zhidan Liu,Ying Huang,Sylvia J. Degrado,Dong Xiao,Jun Qin,Robert Aslanian,Brian A. McKittrick,Scott Greenfeder,Margaret van Heek,Madhu Chintala,Anandan Palani	12
7	Discovery of novel orally active ureido NPY Y5 receptor antagonists 2007 ·Bioorganic & Medicinal Chemistry Letters ·Guo‐Qing Li,Andrew W. Stamford,Ying Huang,Kuo-Chi Cheng,John A. Cook,Constance Farley,(unknown),Lorraine Ghibaudi,William J. Greenlee,M. Guzzi,Margaret van Heek,Joyce Hwa,(unknown),Deborra Mullins,Eric M. Parker,(unknown),Xiaoping Zhang	14
8	Tetrahydroisoquinolines as MCH-R1 antagonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),Qiang Li,Wen‐Lian Wu,Duane A. Burnett,William J. Greenlee,Kathleen O’Neill,Brian E. Hawes,Margaret van Heek,M P Graziano	6
9	Ezetimibe potently inhibits cholesterol absorption but does not affect acute hepatic or intestinal cholesterol synthesis in rats 2003 ·British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,April Smith‐Torhan,Harry R. Davis	51
10	Characterization of diet-induced obese rats that develop persistent obesity after 6 months of high-fat followed by 1 month of low-fat diet 2002 ·Brain Research ·Jun Gao,Lorraine Ghibaudi,Margaret van Heek,Joyce Hwa	41
11	Fat Intake Affects Adiposity, Comorbidity Factors, and Energy Metabolism of Sprague‐Dawley Rats 2002 ·Obesity Research ·Lorraine Ghibaudi,John A. Cook,Constance Farley,Margaret van Heek,Joyce Hwa	169
12	Neuropeptide Y receptors as targets for anti-obesity drug development: perspective and current status 2002 ·European Journal of Pharmacology ·Eric M. Parker,Margaret van Heek,Andrew W. Stamford	64
13	The cholesterol absorption inhibitor, ezetimibe, decreases diet-induced hypercholesterolemia in monkeys 2001 ·European Journal of Pharmacology ·Margaret van Heek,Douglas S. Compton,Harry R. Davis	109
14	Ezetimibe selectively inhibits intestinal cholesterol absorption in rodents in the presence and absence of exocrine pancreatic function 2001 ·British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,Harry R. Davis	173
15	Comparison of the activity and disposition of the novel cholesterol absorption inhibitor, SCH58235, and its glucuronide, SCH60663 2000 ·British Journal of Pharmacology ·Margaret van Heek,Constance Farley,Douglas S. Compton,Lizbeth Hoos,Kevin B. Alton,Edmund J. Sybertz,Harry R. Davis	265
16	Cholesteryl Hydroperoxyoctadecadienoate from Oxidized Low Density Lipoprotein Inactivates Platelet-derived Growth Factor 1998 ·Journal of Biological Chemistry ·Margaret van Heek,David Schmitt,Paul Toren,Martha K. Cathcart,Paul E. DiCorleto	20
17	Effect of Chronic Central Administration of Glucagon‐Like Peptide‐1 (7–36) Amide on Food Consumption and Body Weight in Normal and Obese Rats 1998 ·Obesity Research ·Harry R. Davis,Deborra Mullins,Jesse M. Pines,Lizbeth Hoos,(unknown),Douglas S. Compton,Michael P. Graziano,Edmund J. Sybertz,Catherine D. Strader,Margaret van Heek	49
18	The Relationship of Tissue Localization, Distribution and Turnover to Feeding After Intraperitoneal¹²⁵I-Leptin Administration toob/obanddb/dbMice 1996 ·Hormone and Metabolic Research ·Margaret van Heek,Donald E. Mullins,Michael D. Wirth,(unknown),Ahmad Fawzi,Douglas S. Compton,Christopher France,Lizbeth Hoos,R Casale,Edmund J. Sybertz,Catherine D. Strader,(unknown)	45
19	Purification of Milligram Quantities of Human Leptin From RecombinantE. Coli 1996 ·Hormone and Metabolic Research ·Ahmad Fawzi,(unknown),Margaret van Heek,(unknown)	16
20	The Liptin Haemopoietic Cytokine Fold is Stabilized by an Intrachain Disulfide Bond 1996 ·Hormone and Metabolic Research ·Fernando Rock,S. Altmann,Margaret van Heek,Rob Kastelein,J. Fernando Bazán	46

About Margaret van Heek

Margaret van Heek is a scholar working on Endocrine and Autonomic Systems, Biochemistry and Nutrition and Dietetics, having authored 40 papers that have together received 2.7k indexed citations. Recurring topics across this work include Cholesterol and Lipid Metabolism (13 papers), Regulation of Appetite and Obesity (11 papers) and Adipose Tissue and Metabolism (7 papers). The work is most often cited by research in Endocrine and Autonomic Systems (887 citations), Nutrition and Dietetics (621 citations) and Physiology (684 citations). Margaret van Heek has collaborated with scholars based in United States, United Kingdom and China. Frequent co-authors include Douglas S. Compton, Harry R. Davis, Edmund J. Sybertz, Constance Farley, Lizbeth Hoos, Catherine D. Strader, Ahmad Fawzi, Joyce Hwa, John A. Cook and M P Graziano. Their work appears in journals such as Journal of Biological Chemistry, Journal of Clinical Investigation and Diabetes.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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