Lyann Sim

2.2k total citations
40 papers, 1.7k citations indexed

About

Lyann Sim is a scholar working on Biotechnology, Molecular Biology and Organic Chemistry. According to data from OpenAlex, Lyann Sim has authored 40 papers receiving a total of 1.7k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Biotechnology, 22 papers in Molecular Biology and 21 papers in Organic Chemistry. Recurrent topics in Lyann Sim's work include Enzyme Production and Characterization (27 papers), Carbohydrate Chemistry and Synthesis (21 papers) and Glycosylation and Glycoproteins Research (16 papers). Lyann Sim is often cited by papers focused on Enzyme Production and Characterization (27 papers), Carbohydrate Chemistry and Synthesis (21 papers) and Glycosylation and Glycoproteins Research (16 papers). Lyann Sim collaborates with scholars based in Canada, United States and Switzerland. Lyann Sim's co-authors include David R. Rose, Buford L. Nichols, Bernardine M. Pinto, Roberto Quezada‐Calvillo, Erwin E. Sterchi, Sankar Mohan, Z-Y Li, O. P. Ward, Hassan Y. Naim and N. Ravindranath and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Angewandte Chemie International Edition.

In The Last Decade

Lyann Sim

38 papers receiving 1.7k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Lyann Sim Canada 21 613 528 499 438 418 40 1.7k
Gyöngyi Gyémánt Hungary 21 590 1.0× 408 0.8× 170 0.3× 174 0.4× 223 0.5× 82 1.5k
Yuanxia Sun China 34 1.4k 2.3× 307 0.6× 157 0.3× 966 2.2× 449 1.1× 99 2.9k
Yuesheng Dong China 28 988 1.6× 153 0.3× 116 0.2× 495 1.1× 151 0.4× 101 2.1k
Hossam M. Hassan Egypt 30 803 1.3× 464 0.9× 315 0.6× 81 0.2× 70 0.2× 107 2.3k
Michael Hellwig Germany 30 780 1.3× 143 0.3× 109 0.2× 605 1.4× 346 0.8× 87 2.9k
Chantal Barthomeuf France 25 990 1.6× 288 0.5× 228 0.5× 65 0.1× 258 0.6× 67 2.0k
Atia‐tul Wahab Pakistan 23 770 1.3× 55 0.1× 555 1.1× 286 0.7× 81 0.2× 135 1.7k
Woo Duck Seo South Korea 29 1.0k 1.7× 109 0.2× 298 0.6× 217 0.5× 349 0.8× 157 2.7k
C. Sadasivan India 22 634 1.0× 72 0.1× 221 0.4× 120 0.3× 56 0.1× 84 1.7k
Hye‐Young Seo South Korea 22 621 1.0× 91 0.2× 64 0.1× 108 0.2× 233 0.6× 108 1.9k

Countries citing papers authored by Lyann Sim

Since Specialization
Citations

This map shows the geographic impact of Lyann Sim's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lyann Sim with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lyann Sim more than expected).

Fields of papers citing papers by Lyann Sim

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lyann Sim. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lyann Sim. The network helps show where Lyann Sim may publish in the future.

Co-authorship network of co-authors of Lyann Sim

This figure shows the co-authorship network connecting the top 25 collaborators of Lyann Sim. A scholar is included among the top collaborators of Lyann Sim based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lyann Sim. Lyann Sim is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Chen, Hongming, Lyann Sim, Deepesh Panwar, et al.. (2024). An alternative broad-specificity pathway for glycan breakdown in bacteria. Nature. 631(8019). 199–206. 8 indexed citations
2.
Tian, Yuqing, L.J. Worrall, Lyann Sim, et al.. (2024). Cobalt as a Cofactor for α-Galactosaminidase-Catalyzed Cleavage of Blood Group Antigens. ACS Catalysis. 14(17). 13497–13508.
3.
Wardman, Jacob F., Lyann Sim, Andreas Geissner, et al.. (2023). A high-throughput screening platform for enzymes active on mucin-type O-glycoproteins. Nature Chemical Biology. 19(10). 1246–1255. 9 indexed citations
4.
Sim, Lyann, Jacob F. Wardman, Andreas Geissner, et al.. (2023). Vinyl Halide‐Modified Unsaturated Cyclitols are Mechanism‐Based Glycosidase Inhibitors. Angewandte Chemie International Edition. 62(21). e202301258–e202301258. 2 indexed citations
5.
Siren, Erika M. J., Lyann Sim, Qiunong Guan, et al.. (2021). Prevention of vascular-allograft rejection by protecting the endothelial glycocalyx with immunosuppressive polymers. Nature Biomedical Engineering. 5(10). 1202–1216. 18 indexed citations
6.
Rahfeld, Peter, Lyann Sim, Iren Constantinescu, et al.. (2019). An enzymatic pathway in the human gut microbiome that converts A to universal O type blood. Nature Microbiology. 4(9). 1475–1485. 54 indexed citations
7.
Lizak, Christian, L.J. Worrall, Lars Baumann, et al.. (2017). X-ray crystallographic structure of a bacterial polysialyltransferase provides insight into the biosynthesis of capsular polysialic acid. Scientific Reports. 7(1). 5842–5842. 16 indexed citations
8.
Sim, Lyann, Sophie R. Beeren, David Dauvillée, et al.. (2014). Crystal Structure of the Chlamydomonas Starch Debranching Enzyme Isoamylase ISA1 Reveals Insights into the Mechanism of Branch Trimming and Complex Assembly. Journal of Biological Chemistry. 289(33). 22991–23003. 46 indexed citations
9.
Lin, Amy Hui‐Mei, Buford L. Nichols, Roberto Quezada‐Calvillo, et al.. (2012). Unexpected High Digestion Rate of Cooked Starch by the Ct-Maltase-Glucoamylase Small Intestine Mucosal α-Glucosidase Subunit. PLoS ONE. 7(5). e35473–e35473. 46 indexed citations
10.
11.
Sim, Lyann, et al.. (2010). Structural Basis for Substrate Selectivity in Human Maltase-Glucoamylase and Sucrase-Isomaltase N-terminal Domains. Journal of Biological Chemistry. 285(23). 17763–17770. 190 indexed citations
12.
Cardona, Francesca, Camilla Parmeggiani, Enrico Faggi, et al.. (2009). Total Syntheses of Casuarine and Its 6‐O‐α‐Glucoside: Complementary Inhibition towards Glycoside Hydrolases of the GH31 and GH37 Families. Chemistry - A European Journal. 15(7). 1627–1636. 80 indexed citations
13.
Sim, Lyann, Roberto Quezada‐Calvillo, Erwin E. Sterchi, Buford L. Nichols, & David R. Rose. (2007). Human Intestinal Maltase–Glucoamylase: Crystal Structure of the N-Terminal Catalytic Subunit and Basis of Inhibition and Substrate Specificity. Journal of Molecular Biology. 375(3). 782–792. 273 indexed citations
14.
Mohan, Sankar, Lyann Sim, David R. Rose, & Bernardine M. Pinto. (2007). Synthesis of S-alkylated sulfonium-ions and their glucosidase inhibitory activities against recombinant human maltase glucoamylase. Carbohydrate Research. 342(7). 901–912. 28 indexed citations
15.
Ao, Zihua, Roberto Quezada‐Calvillo, Lyann Sim, et al.. (2007). Evidence of native starch degradation with human small intestinal maltase‐glucoamylase (recombinant). FEBS Letters. 581(13). 2381–2388. 59 indexed citations
16.
Ravindranath, N., Lyann Sim, David R. Rose, & B. Mario Pinto. (2007). Synthesis and glycosidase inhibitory activities of chain-modified analogues of the glycosidase inhibitors salacinol and blintol. Carbohydrate Research. 342(12-13). 1888–1894. 9 indexed citations
17.
Chen, Wang, et al.. (2006). Synthesis, enzymatic activity, and X-ray crystallography of an unusual class of amino acids. Bioorganic & Medicinal Chemistry. 14(24). 8332–8340. 14 indexed citations
18.
Sim, Lyann, D.A. Kuntz, Dagmar Hahn, et al.. (2006). Inhibition of recombinant human maltase glucoamylase by salacinol and derivatives. FEBS Journal. 273(12). 2673–2683. 73 indexed citations
19.
Evans, R., et al.. (2006). Testing by Sysmex UF-100 flow cytometer and with bacterial culture in a diagnostic laboratory: a comparison. Journal of Clinical Pathology. 59(6). 661–662. 31 indexed citations
20.
Sim, Lyann, O. P. Ward, & Z-Y Li. (1997). Production and characterisation of a biosurfactant isolated from Pseudomonas aeruginosa UW-1. Journal of Industrial Microbiology & Biotechnology. 19(4). 232–238. 156 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact

Rankless by CCL
2026