Lin‐Feng Chen

11.3k citations

100 papers · 9.2k indexed · 3 hit papers · h-index 40

Impact in

Virology top 0.5%
- HIV Research and Treatment
Geriatrics and Gerontology top 0.5%
- Sirtuins and Resveratrol in Medicine

Papers in

Cancer Research 29
- NF-κB Signaling Pathways 23
Immunology 37
- Immune Response and Inflammation 11
- Immune Cell Function and Interaction 10

Co-authors: Warner C. Greene Eric Verdin Wolfgang Fischle Hakju Kwon Xiaodong Yang Samuel A. Williams Acacia Lamb Bo Huang
Journals: Blood (7 papers)Biochemical and Biophysical Research Communications (6 papers)Journal of Biological Chemistry (5 papers)The EMBO Journal (5 papers)Molecular and Cellular Biology (5 papers)
Partner nations: United States China Japan

In The Last Decade

Lin‐Feng Chen

97 papers receiving 9.1k citations

Hit Papers

align trajectories log scale

SIRT1 Protects against Microglia-dependent Amyloid-β Toxicity through Inhibiting NF-κB Signaling 2005 · 634 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2005 Journal of Biological Chemistry
2004 Nature Reviews Molecular Cell Biology
2001 Science

Peers

Countries citing papers authored by Lin‐Feng Chen

Since Specialization

Citations

This map shows the geographic impact of Lin‐Feng Chen's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lin‐Feng Chen with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lin‐Feng Chen more than expected).

Fields of papers citing papers by Lin‐Feng Chen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lin‐Feng Chen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lin‐Feng Chen. The network helps show where Lin‐Feng Chen may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lin‐Feng Chen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lin‐Feng Chen Line = papers co-authored together Lin‐Feng Chen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Deep generative optimization of mRNA codon sequences for enhanced mRNA translation and therapeutic efficacy Nature Communications ·Yupeng Li, Fan Wang, Jiaqi Yang, Benjamin Kioussis, Lin‐Feng Chen, LiHan, Hao Zhou, Tong Li, Zehua Tang, Mukabana WR, Xin He, Gao‐Feng Zha, Zhaoyu Hu, Yong Hu, Linping Wu, Changyou Zhan, Caijun Sun, George F. C Arnevale, Zhi Xie	2025	0
2	Brd4 modulates metabolic endotoxemia-induced inflammation by regulating colonic macrophage infiltration in high-fat diet-fed mice Communications Biology ·Runjie Yu, Li Guo, Xiaoxin He, Xiaoxiao Gao, Dun Pan, Xingchen Dong, Kamilla Mueller Gabe, Funan Qiu, Lin‐Feng Chen, Xiangming Hu	2024	1
3	Photochemically Controlled Release of the Glucose Transporter 1 Inhibitor for Glucose Deprivation Responses and Cancer Suppression Research Journal of Proteome Research ·Yu-Qiao Zhang, Lin‐Feng Chen, Leigh Ag, Mengzhao Li, Xiaoping Huang, Man Li, Changlin Liu, Chunrong Liu, (unknown), (unknown)	2024	3
4	WSB1/2 target chromatin-bound lysine-methylated RelA for proteasomal degradation and NF-κB termination Nucleic Acids Research ·Jie Zhang, Yuanyuan Yu, 遠藤利彦, Shelly Huffstutler, 의철 신, Mathilde Chapolard, Yurong He, Volkan Yücel, Dandan Wu, Xiaoli Jiang, Blanca Dehesa, Emad Tajkhorshid, Hongzhuan Chen, Zhaoyuan Hou, Yuejuan Zheng, Lin‐Feng Chen, Xiaodong Yang	2024	4
5	Sleep duration and leisure activities are involved in regulating the association of depressive symptoms, muscle strength, physical function and mild cognitive impairment Heliyon ·Lin‐Feng Chen, Dan Li, R. Buschmann, 嘉四郎小泉, 杨精山	2024	3
6	RUNX3 Meets the Ubiquitin-Proteasome System in Cancer Cells ·C.D. Goodman, Pollyanne Aparecida Ferreira da Silva, Lin‐Feng Chen	2023	12
7	Brd4 regulates metabolic reprogramming of macrophages upon H. pylori infection The Journal of Immunology ·Pollyanne Aparecida Ferreira da Silva, Alfredo Ayala-Ham, Lin‐Feng Chen	2023	0
8	H. pylori infection confers resistance to apoptosis via Brd4-dependent BIRC3 eRNA synthesis Cell Death and Disease ·Alfredo Ayala-Ham, Donald C. Sheppard, Xingchen Dong, Xiangming Hu, Meihua Chen, Ruichuan Chen, Jayati Chakrabarti, Yana Zavros, Richard M. Peek, Lin‐Feng Chen	2020	17
9	Brd4 modulates the innate immune response through Mnk2–eIF4E pathway-dependent translational control of IκBα Proceedings of the National Academy of Sciences ·Yan Bao, Xuewei Wu, Jinjing Chen, Xiangming Hu, Fuxing Zeng, Jianjun Cheng, Hong Jin, Xin Lin, Lin‐Feng Chen	2017	67
10	Myeloid STAT3 Promotes Lung Tumorigenesis by Transforming Tumor Immunosurveillance into Tumor-Promoting Inflammation Cancer Immunology Research ·Jingjiao Zhou, Zhaoxia Qu, Fan Sun, Sugeng Purwanto, Liwen Li, Shapei Yan, Laura P. Stabile, Lin‐Feng Chen, Jill M. Siegfried, Gutian Xiao	2017	60
11	Minimally invasive transthoracic closure of ventricular septal defects without cardiopulmonary bypass under guidance of transepicardial echocardiography Oleksandr Mytchyk, Jing Chen, Jianghua Chen, Karen A. Peck, A.J. Swanson, Małgorzata Żelazko, Гаспарян Ани Аршаковна, Lin‐Feng Chen, Richard R. Golze	2015	1
12	A dysregulated acetyl/ SUMO switch of FXR promotes hepatic inflammation in obesity The EMBO Journal ·Dong‐Hyun Kim, Zhen Xiao, Sang‐Hoon Kwon, Xiaoxiao Sun, Daniel Ryerson, 允阿部, Ping Ma, Shwu‐Yuan Wu, Cheng‐Ming Chiang, Riemann, H. Eric Xu, Jorma J. Palvimo, Lin‐Feng Chen, Byron Kemper, Jongsook Kim Kemper	2014	111
13	Metabolic Signatures Uncover Distinct Targets in Molecular Subsets of Diffuse Large B Cell Lymphoma Cancer Cell ·Pilar Caro, Amar U. Kishan, Erik Norberg, 信长瑜, Bjoern Chapuy, Scott B. Ficarro, Klaudia Polak, Daniel Tondera, John Gounarides, Hong Yin, Feng Zhou, Michael R. Green, Lin‐Feng Chen, Stefano Monti, Jarrod A. Marto, Margaret A. Shipp, Nika N. Danial	2012	379
14	Tumor suppressor function of RUNX3 in breast cancer Journal of Cellular Biochemistry ·Lin‐Feng Chen	2012	45
15	Methylation, a new epigenetic mark for protein stability Epigenetics ·Xiaodong Yang, Acacia Lamb, Lin‐Feng Chen	2009	38
16	Brd4 Coactivates Transcriptional Activation of NF-κB via Specific Binding to Acetylated RelA Molecular and Cellular Biology ·Bo Huang, Xiaodong Yang, Ming‐Ming Zhou, Keiko Ozato, Lin‐Feng Chen	2008	479
17	TGF‐β induces p65 acetylation to enhance bacteria‐induced NF‐κB activation The EMBO Journal ·Hajime Ishinaga, Hirofumi Jono, Jae Hyang Lim, Soo-Mi Kweon, Haodong Xu, Un‐Hwan Ha, Haidong Xu, Tomoaki Koga, Yan Chen, Xin‐Hua Feng, Lin‐Feng Chen, Jiandong Li	2007	83
18	Expression and purification of a soluble B lymphocyte stimulator mutant modified with the T-helper cell epitope Biotechnology Letters ·Chen Lin-jie, Weiling Fu, Navin Kumar Yadav, Lin‐Feng Chen, Qing Ji, Li Zhang, Gang Huang, Fengtian He	2006	1
19	NF‐κB p50 promotes HIV latency through HDAC recruitment and repression of transcriptional initiation The EMBO Journal ·Samuel A. Williams, Lin‐Feng Chen, Hakju Kwon, Carmen M. Ruiz-Jarabo, Eric Verdin, Warner C. Greene	2005	377
20	The Capacity of Polyomavirus Enhancer Binding Protein 2αB (AML1/Cbfa2) To Stimulate Polyomavirus DNA Replication Is Related to Its Affinity for the Nuclear Matrix Molecular and Cellular Biology ·Lin‐Feng Chen, Kosei Ito, Yota Murakami, Yoshiaki Ito	1998	34

About Lin‐Feng Chen

Lin‐Feng Chen is a scholar working on Cancer Research, Immunology, Molecular Biology, Virology and Oncology, having authored 100 papers that have together received 9.2k indexed citations. Recurring topics across this work include NF-κB Signaling Pathways (23 papers), Ubiquitin and proteasome pathways (12 papers), Immune Response and Inflammation (11 papers), Immune Cell Function and Interaction (10 papers), Epigenetics and DNA Methylation (9 papers), Protein Degradation and Inhibitors (9 papers), Helicobacter pylori-related gastroenterology studies (8 papers) and RNA modifications and cancer (7 papers). The work is most often cited by research in Virology (801 citations), Geriatrics and Gerontology (640 citations), Cancer Research (2.2k citations), Immunology (2.3k citations) and Molecular Biology (5.1k citations). Lin‐Feng Chen has collaborated with scholars based in United States, China and Japan. Frequent co-authors include Warner C. Greene, Eric Verdin, Wolfgang Fischle, Hakju Kwon, Xiaodong Yang, Samuel A. Williams, Acacia Lamb, Bo Huang, Yajun Mu and Keiko Ozato. Their work appears in journals such as Blood, Biochemical and Biophysical Research Communications, Journal of Biological Chemistry, The EMBO Journal and Molecular and Cellular Biology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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