Xin Lin

21.2k citations

260 papers · 17.4k · 3 hit papers · h-index 75

Impact in

Immunology top 0.2%
- Immune Cell Function and Interaction
- Immune Response and Inflammation
- T-cell and B-cell Immunology
- interferon and immune responses
Cancer Research top 0.5%
- NF-κB Signaling Pathways

Papers in

Immunology 96
- Immune Response and Inflammation 35
- Immune Cell Function and Interaction 29
- interferon and immune responses 19
- Immunotherapy and Immune Responses 15
Cancer Research 63
- NF-κB Signaling Pathways 57

Co-authors: Marzenna Blonska (18 shared papers)Xuelin Huang (1 shared paper)Zhicheng Zhou (1 shared paper)Xiayu Rao (1 shared paper)Yun You (14 shared papers)Hongxiu Li (10 shared papers)Warner C. Greene (7 shared papers)David E. Cane (8 shared papers)
Journals: Journal of Biological Chemistry (18 papers)The Journal of Immunology (16 papers)Molecular and Cellular Biology (10 papers)Immunity (9 papers)Cellular and Molecular Immunology (8 papers)
Partner nations: United States China Japan

In The Last Decade

Xin Lin

253 papers receiving 17.1k citations

Xin Lin's Hit Papers

align trajectories log scale

Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial 2019 · 262 citations

What are hit papers?

Paper score: A paper's citations measured against the top-1% bar of its own field and year: the square root of citations ÷ bar, so 1 means right at the bar and 2 means four times its citations. The bar blends the citation counts that enter the top 1% of the paper's subfields in its year (weighted 89.5%), of those subfields over all years (0.5%) and of its year across all fields (10%); a subfield and year with fewer than 400 papers takes its year's bar. Papers from 2026 are not scored yet: in an unfinished year, when a paper appeared matters more than how it is cited.

Hit paper: A paper cited at least 1.5× the top-1% bar of its field and year: a paper score of at least √1.5.

2019 Annals of the Rheumatic Diseases
2014 Immunity
2013 PubMed

Peers

Countries citing papers authored by Xin Lin

Since Specialization

Citations

This map shows the geographic impact of Xin Lin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Xin Lin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Xin Lin more than expected).

Fields of papers citing papers by Xin Lin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Xin Lin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Xin Lin. The network helps show where Xin Lin may publish in the future.

Co-authors

The 25 scholars most cited alongside Xin Lin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Xin Lin Line = papers co-authored together Xin Lin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 260 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	An improvement of the 2ˆ(-delta delta CT) method for quantitative real-time polymerase chain reaction data analysis. PubMed ·Xiayu Rao, Xuelin Huang, Zhicheng Zhou, Xin Lin Hit paper breakdown →	2013	1365
2	Inflammatory T Cell Responses Rely on Amino Acid Transporter ASCT2 Facilitation of Glutamine Uptake and mTORC1 Kinase Activation Immunity ·Mako Nakaya, Yichuan Xiao, Xiaofei Zhou, Chang Jae-Hoon, Mikyoung Chang, Xuhong Cheng, Marzenna Blonska, Xin Lin Hit paper breakdown →	2014	719
3	The E3 Ligase TRAF6 Regulates Akt Ubiquitination and Activation Science ·Wei-Lei Yang, Jing Wang, Chia‐Hsin Chan, Szu-Wei Lee, Alejandro D. Campos, Betty Lamothe, Lana Hur, Brian C. Grabiner	2009	534
4	The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens Nature Immunology ·Yen-Michael S. Hsu, Yongliang Zhang, Yun You, Donghai Wang, Hongxiu Li, Omar Duramad, F. Xiao‐Feng Qin, Chen Dong	2006	366
5	Disruption of Gastrulation and Heparan Sulfate Biosynthesis in EXT1-Deficient Mice Developmental Biology ·Xin Lin, Ge Wei, Zheng-Zheng Shi, Laurence Dryer, Jeffrey D. Esko, Dan E. Wells, Martin M. Matzuk	2000	357
6	IL-6/JAK1 pathway drives PD-L1 Y112 phosphorylation to promote cancer immune evasion Journal of Clinical Investigation ·Li-Chuan Chan, Chia‐Wei Li, Weiya Xia, Jung-Mao Hsu, Heng‐Huan Lee, Jong‐Ho Cha, Hung-Ling Wang, Wen-Hao Yang	2019	312
7	C-Type Lectin Receptors Dectin-3 and Dectin-2 Form a Heterodimeric Pattern-Recognition Receptor for Host Defense against Fungal Infection Immunity ·Lele Zhu, Xue Qiang Zhao, Changying Jiang, Yun You, Xiao‐Ping Chen, Yuan-Ying Jiang, Xin‐Ming Jia, Xin Lin	2013	276
8	A requirement for CARMA1 in TCR-induced NF-κB activation Nature Immunology ·Donghai Wang, Yun You, Sara M. Case, Linda M. McAllister‐Lucas, Lin Wang, Peter S. DiStefano, Gabriel Núñez, John Bertin	2002	263
9	Efficacy and safety of low-dose IL-2 in the treatment of systemic lupus erythematosus: a randomised, double-blind, placebo-controlled trial Annals of the Rheumatic Diseases ·Jing He, Ruijun Zhang, Miao Shao, Xiaozhen Zhao, Miao Miao, Jiali Chen, Jiajia Liu, Xiaoying Zhang Hit paper breakdown →	2019	262
10	Phosphorylation of CARMA1 Plays a Critical Role in T Cell Receptor-Mediated NF-κB Activation Immunity ·Reiko Matsumoto, Donghai Wang, Marzenna Blonska, Hongxiu Li, Masayuki Kobayashi, Bhanu P. Pappu, Yuhong Chen, Demin Wang	2005	253
11	Ubiquitination of RIP Is Required for Tumor Necrosis Factor α-induced NF-κB Activation Journal of Biological Chemistry ·Hongxiu Li, Masayuki Kobayashi, Marzenna Blonska, Yun You, Xin Lin	2006	246
12	Protein Kinase C-θ Participates in NF-κB Activation Induced by CD3-CD28 Costimulation through Selective Activation of IκB Kinase β Molecular and Cellular Biology ·Xin Lin, Alison O’Mahony, Yajun Mu, Romas Geleziunas, Warner C. Greene	2000	235
13	Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail Molecular and Cellular Biology ·Hyun Jung Kim, Beate C. Litzenburger, Xiaojiang Cui, David A. Delgado, Brian C. Grabiner, Xin Lin, Michael T. Lewis, Marco M. Gottardis	2007	200
14	Human T-Cell Leukemia Virus Type 1 Tax Induction of NF-κB Involves Activation of the IκB Kinase α (IKKα) and IKKβ Cellular Kinases Molecular and Cellular Biology ·Romas Geleziunas, Sharon Ferrell, Xin Lin, Yajun Mu, Emmett T. Cunningham, Mark Grant, Margery A. Connelly, John Hambor	1998	193
15	The 90-kDa Ribosomal S6 Kinase (pp90rsk) Phosphorylates the N-terminal Regulatory Domain of IκBα and Stimulates Its Degradation in Vitro Journal of Biological Chemistry ·Lucy Y. Ghoda, Xin Lin, Warner C. Greene	1997	192
16	Enhancing CAR-T cell efficacy in solid tumors by targeting the tumor microenvironment Cellular and Molecular Immunology ·Guangna Liu, Xueqiang Zhao, Xin Lin +1 other	2021	190
17	CD3/CD28 Costimulation-Induced NF-κB Activation Is Mediated by Recruitment of Protein Kinase C-θ, Bcl10, and IκB Kinase β to the Immunological Synapse through CARMA1 Molecular and Cellular Biology ·Donghai Wang, Reiko Matsumoto, Yun You, Tuanjie Che, Xue-Yan Lin, Xue-Yan Lin, Sarah L. Gaffen, Xin Lin	2003	189
18	C-type lectin receptor-induced NF-κB activation in innate immune and inflammatory responses Cellular and Molecular Immunology ·Lara M. Kingeter, Xin Lin	2012	188
19	Circular RNA cancer vaccines drive immunity in hard-to-treat malignancies Theranostics ·Hongjian Li, Kun Peng, Kai Liang Yang, Wenbo Ma, Shaolong Qi, Xinyang Yu, Jia He, Xin Lin	2022	188
20	The Proto-Oncogene Cot Kinase Participates in CD3/CD28 Induction of NF-κB Acting through the NF-κB-Inducing Kinase and IκB Kinases Immunity ·Xin Lin, Emmett T. Cunningham, Yajun Mu, Romas Geleziunas, Warner C. Greene	1999	187

About Xin Lin

Xin Lin is a scholar working on Immunology, Cancer Research, Molecular Biology, Oncology and Infectious Diseases, having authored 260 papers that have together received 17.4k indexed citations. Recurring topics across this work include NF-κB Signaling Pathways (57 papers), Immune Response and Inflammation (35 papers), Immune Cell Function and Interaction (29 papers), interferon and immune responses (19 papers), Antifungal resistance and susceptibility (19 papers), Cytokine Signaling Pathways and Interactions (15 papers), Immunotherapy and Immune Responses (15 papers) and CAR-T cell therapy research (14 papers). The work is most often cited by research in Immunology (6.0k citations), Cancer Research (3.7k citations), Oncology (2.8k citations), Molecular Biology (7.4k citations) and Infectious Diseases (1.4k citations). Xin Lin has collaborated with scholars based in United States, China and Japan. Frequent co-authors include Marzenna Blonska, Xuelin Huang, Zhicheng Zhou, Xiayu Rao, Yun You, Hongxiu Li, Warner C. Greene, David E. Cane, Romas Geleziunas and Donghai Wang. Their work appears in journals such as Journal of Biological Chemistry, The Journal of Immunology, Molecular and Cellular Biology, Immunity and Cellular and Molecular Immunology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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Xin Lin's Hit Papers

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Countries citing papers authored by Xin Lin

Fields of papers citing papers by Xin Lin

All Works

About Xin Lin

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