Lin Leng

16.5k total citations · 3 hit papers
211 papers, 12.8k citations indexed

About

Lin Leng is a scholar working on Immunology, Cellular and Molecular Neuroscience and Pharmacology. According to data from OpenAlex, Lin Leng has authored 211 papers receiving a total of 12.8k indexed citations (citations by other indexed papers that have themselves been cited), including 190 papers in Immunology, 85 papers in Cellular and Molecular Neuroscience and 15 papers in Pharmacology. Recurrent topics in Lin Leng's work include Macrophage Migration Inhibitory Factor (183 papers), Nuclear Receptors and Signaling (83 papers) and Apelin-related biomedical research (14 papers). Lin Leng is often cited by papers focused on Macrophage Migration Inhibitory Factor (183 papers), Nuclear Receptors and Signaling (83 papers) and Apelin-related biomedical research (14 papers). Lin Leng collaborates with scholars based in United States, Germany and China. Lin Leng's co-authors include Richard Bucala, Richard Bucala, Jürgen Bernhagen, Seamas C. Donnelly, Courtney McDonald, Hongqi Lue, Xin Du, Christine N. Metz, Elias Lolis and Günter Fingerle‐Rowson and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Biological Chemistry.

In The Last Decade

Lin Leng

207 papers receiving 12.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

MIF is a noncognate ligand of CXC chemokine receptors in inflammatory and atherogenic cell recruitment

2007 990 citations Jürgen Bernhagen, Hongqi Lue et al. profile →
MIF Signal Transduction Initiated by Binding to CD74

2003 895 citations Lin Leng, Christine N. Metz et al. The Journal of Experimental Medicine profile →
CD44 Is the Signaling Component of the Macrophage Migration Inhibitory Factor-CD74 Receptor Complex

2006 530 citations Lin Leng, Xin Du et al. profile →

Peers

Countries citing papers authored by Lin Leng

Since Specialization

Citations

This map shows the geographic impact of Lin Leng's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lin Leng with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lin Leng more than expected).

Fields of papers citing papers by Lin Leng

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lin Leng. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lin Leng. The network helps show where Lin Leng may publish in the future.

Co-authorship network of co-authors of Lin Leng

This figure shows the co-authorship network connecting the top 25 collaborators of Lin Leng. A scholar is included among the top collaborators of Lin Leng based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lin Leng. Lin Leng is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Improving immunotherapy responses by dual inhibition of macrophage migration inhibitory factor and PD-1 2025 ·JCI Insight ·Thuy Tran, (unknown), Lais Osmani, (unknown), (unknown), Marta Piecychna, Lin Leng, Michelle E. Armstrong, Seamas C. Donnelly, Carlo Bifulco, Terri Clister, Rajan P. Kulkarni, Lin Zhang, Mario Sznol, Lucia B. Jilaveanu, Harriet M. Kluger, Insoo Kang, Richard Bucala	0
2	A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation 2024 ·Metabolism ·Hao Wang, (unknown), (unknown), Zehui Li, Lin Leng, Bi Zhao, Richard Bucala, Ji Li	11
3	Downregulation of adipose LPL by PAR2 contributes to the development of hypertriglyceridemia 2024 ·JCI Insight ·(unknown), Liujun Chen, (unknown), (unknown), Haibin Tong, Hong Wu, (unknown), Lin Leng, Sukhinder Kaur Cheema, Guang Sun, Zhengyuan Xia, John J. McGuire, Brian Rodrigues, (unknown), Richard Bucala, Dake Qi	8
4	A small-molecule allele-selective transcriptional inhibitor of the MIF immune susceptibility locus 2024 ·Journal of Biological Chemistry ·Jia Li, Lin Leng, Georgios Pantouris, R. Manjula, Marta Piecychna, Laura Abriola, Buqu Hu, Elias Lolis, Michelle E. Armstrong, Seamas C. Donnelly, Richard Bucala	2
5	MIF-Modulated Spinal Proteins Associated with Persistent Bladder Pain: A Proteomics Study 2024 ·International Journal of Molecular Sciences ·Shaojing Ye, Nilesh M. Agalave, Fei Ma, (unknown), (unknown), Payam Emami Khoonsari, Lin Leng, Camilla I. Svensson, Richard Bucala, Kim Kultima, Pedro L. Vera	1
6	830 Inhibition of macrophage migration inhibitory factor (MIF) to overcome immune checkpoint resistance in melanoma 2023 ·SHILAP Revista de lepidopterología ·(unknown), (unknown), Lin Leng, Lin Zhang, Lucia B. Jilaveanu, Harriet M. Kluger, Richard Bucala, Thuy Tran	1
7	Urothelial Oxidative Stress and ERK Activation Mediate HMGB1-Induced Bladder Pain 2023 ·Cells ·Shaojing Ye, (unknown), Fei Ma, Lin Leng, Richard Bucala, Pedro L. Vera	7
8	Macrophage Migration Inhibitory Factor (MIF) Promotes Increased Proportions of the Highly Permissive Th17-like Cell Profile during HIV Infection 2022 ·Viruses ·(unknown), (unknown), (unknown), (unknown), Lin Leng, Natalia Laufer, María Florencia Quiroga, Richard Bucala, Yanina Ghiglione, Gabriela Turk	4
9	Role of MIF in coordinated expression of hepatic chemokines in patients with alcohol-associated hepatitis 2021 ·JCI Insight ·Kyle L. Poulsen, Xiude Fan, (unknown), Emily Huang, Xiaoqin Wu, Megan R. McMullen, Lin Leng, Richard Bucala, Meritxell Ventura‐Cots, Josepmaria Argemí, Ramón Bataller, Laura E. Nagy	12
10	Extracellular MIF, but not its homologue D-DT, promotes fibroblast motility independently of its receptor complex CD74/CD44 2020 ·Journal of Cell Science ·(unknown), (unknown), Suada Fröhlich, Uwe Plessmann, Henning Urlaub, Lin Leng, Richard Bucala, Robert Grosse, Andreas Meinhardt, Jörg Klug	3
11	The Macrophage Migration Inhibitory Factor (MIF) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery 2020 ·Journal of Clinical Medicine ·Luisa Averdunk, Jürgen Bernhagen, (unknown), Harald Surowy, Hermann‐Josef Lüdecke, Sören Mucha, Patrick Meybohm, Dagmar Wieczorek, Lin Leng, Gernot Marx, David E. Leaf, Alexander Zarbock, Kai Zacharowski, (unknown), Richard Bucala, Christian Stoppe	13
12	Macrophage migration inhibitory factor enhances influenza-associated mortality in mice 2019 ·JCI Insight ·Candice A. Smith, (unknown), Upasana Kulkarni, Sherri C. Wood, Lin Leng, Rachel L. Zemans, Richard Bucala, Daniel R. Goldstein	16
13	Macrophage migration inhibitory factor mediates protease-activated receptor 4-induced bladder pain through urothelial high mobility group box 1 2017 ·Physiological Reports ·Fei Ma, (unknown), Katherine L. Meyer‐Siegler, David E. Hunt, Lin Leng, Richard Bucala, Pedro L. Vera	12
14	Preliminary associations between childhood neglect, MIF, and cortisol: Potential pathways to long‐term disease risk 2014 ·Developmental Psychobiology ·Johanna Bick, (unknown), Lin Leng, Marta Piecychna, Michael J. Crowley, Richard Bucala, Linda C. Mayes, Elena L. Grigorenko	20
15	The Role of Macrophage Migration Inhibitory Factor in Autoimmune Liver Disease 2013 ·Hepatology ·David N. Assis, Lin Leng, Xin Du, Hu Zhang, Gerrit Grieb, Melanie Merk, Alvaro Baeza Garcia, (unknown), Julius Chapiro, Andreas Meinhardt, Yuka Mizue, David J. Nikolic‐Paterson, Jürgen Bernhagen, Marshall M. Kaplan, Hongyu Zhao, James L. Boyer, Richard Bucala	89
16	MIF Produced by Bone Marrow–Derived Macrophages Contributes to Teratoma Progression after Embryonic Stem Cell Transplantation 2012 ·Cancer Research ·Xi Wang, Tianxiang Chen, Lin Leng, Jianqing Fan, Kai Cao, Zhaoxia Duan, Xijing Zhang, Changshun Shao, (unknown), Iman Tadmori, Tianyi Li, Liang Li, Dongming Sun, Shusen Zheng, Andreas Meinhardt, Wise Young, Richard Bucala, Yi Ren	39
17	A Novel Allosteric Inhibitor of Macrophage Migration Inhibitory Factor (MIF) 2012 ·Journal of Biological Chemistry ·Fengwei Bai, Oluwatoyin A. Asojo, Pier F. Cirillo, (unknown), Michel Ledizet, Paul A. Aristoff, Lin Leng, Raymond A. Koski, Thomas Powell, Richard Bucala, Karen Anthony	61
18	A Tautomerase-Null Macrophage Migration-Inhibitory Factor (MIF) Gene Knock-In Mouse Model Reveals That Protein Interactions and Not Enzymatic Activity Mediate MIF-Dependent Growth Regulation 2009 ·Molecular and Cellular Biology ·(unknown), (unknown), (unknown), Nazanin Kabgani, (unknown), Nina Reinart, Raymonde Busch, Anke K. Schütz, Hongqi Lue, Xin Du, Aihua Liu, Huabao Xiong, Yibang Chen, Alice Nemajerová, Michael Hallek, Jürgen Bernhagen, Lin Leng, Richard Bucala	115
19	A Novel, Macrophage Migration Inhibitory Factor Suicide Substrate Inhibits Motility and Growth of Lung Cancer Cells 2008 ·Cancer Research ·(unknown), (unknown), Swen Zierow, Beatriz E. Rendon, G.V. Crichlow, (unknown), Richard Bucala, Lin Leng, Ned B. Smith, Elias Lolis, John O. Trent, Robert A. Mitchell	133
20	A critical role for the host mediator macrophage migration inhibitory factor in the pathogenesis of malarial anemia 2006 ·The Journal of Experimental Medicine ·Michael A. McDevitt, Jianlin Xie, Shanmugasundaram Ganapathy‐Kanniappan, Jason W. Griffith, Aihua Liu, Courtney McDonald, Philip E. Thuma, Victor R. Gordeuk, Christine N. Metz, Robert A. Mitchell, Jeffrey R. Keefer, John R. David, Lin Leng, Richard Bucala	108

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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