John O. Trent

11.9k total citations · 4 hit papers
151 papers, 9.7k citations indexed

About

John O. Trent is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, John O. Trent has authored 151 papers receiving a total of 9.7k indexed citations (citations by other indexed papers that have themselves been cited), including 114 papers in Molecular Biology, 31 papers in Oncology and 21 papers in Immunology. Recurrent topics in John O. Trent's work include DNA and Nucleic Acid Chemistry (60 papers), Advanced biosensing and bioanalysis techniques (57 papers) and RNA Interference and Gene Delivery (34 papers). John O. Trent is often cited by papers focused on DNA and Nucleic Acid Chemistry (60 papers), Advanced biosensing and bioanalysis techniques (57 papers) and RNA Interference and Gene Delivery (34 papers). John O. Trent collaborates with scholars based in United States, Japan and United Kingdom. John O. Trent's co-authors include Jonathan B. Chaires, Paula J. Bates, Robert D. Gray, Donald M. Miller, Andrew N. Lane, Shelia D. Thomas, Rafael del Villar‐Guerra, Damian A. Laber, Terence C. Jenkins and M. Clarke Miller and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of the American Chemical Society and Nucleic Acids Research.

In The Last Decade

John O. Trent

147 papers receiving 9.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Discovery and development of the G-rich oligonucleotide AS1411 as a novel treatment for cancer

2009 696 citations Paula J. Bates, Donald M. Miller et al. profile →
Inhibition of Human Telomerase by a G-Quadruplex-Interactive Compound

1997 664 citations John O. Trent et al. profile →
Stability and kinetics of G-quadruplex structures

2008 619 citations Jonathan B. Chaires, Robert D. Gray et al. Nucleic Acids Research profile →
G‐Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy

2017 403 citations Rafael del Villar‐Guerra, John O. Trent et al. Angewandte Chemie International Edition profile →

Peers

Countries citing papers authored by John O. Trent

Since Specialization

Citations

This map shows the geographic impact of John O. Trent's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John O. Trent with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John O. Trent more than expected).

Fields of papers citing papers by John O. Trent

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John O. Trent. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John O. Trent. The network helps show where John O. Trent may publish in the future.

Co-authorship network of co-authors of John O. Trent

This figure shows the co-authorship network connecting the top 25 collaborators of John O. Trent. A scholar is included among the top collaborators of John O. Trent based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John O. Trent. John O. Trent is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Structure of a 28.5 kDa duplex-embedded G-quadruplex system resolved to 7.4 Å resolution with cryo-EM 2023 ·Nucleic Acids Research ·Robert C. Monsen, Eugene Chua, Jesse B. Hopkins, Jonathan B. Chaires, John O. Trent	17
2	G-quadruplex DNA: A Longer Story 2022 ·Accounts of Chemical Research ·Robert C. Monsen, John O. Trent, Jonathan B. Chaires	46
3	Long promoter sequences form higher-order G-quadruplexes: an integrative structural biology study of c-Myc, k-Ras and c-Kit promoter sequences 2022 ·Nucleic Acids Research ·Robert C. Monsen, Lynn DeLeeuw, William L. Dean, Robert D. Gray, Srinivas Chakravarthy, Jesse B. Hopkins, Jonathan B. Chaires, John O. Trent	26
4	Novel small molecule inhibitor of Kpnβ1 induces cell cycle arrest and apoptosis in cancer cells 2021 ·Experimental Cell Research ·(unknown), Pauline J. van der Watt, (unknown), Sarah Carden, John O. Trent, Virna D. Leaner	8
5	POT1 stability and binding measured by fluorescence thermal shift assays 2021 ·PLoS ONE ·Lynn DeLeeuw, Robert C. Monsen, Vytautas Petrauskas, Robert D. Gray, Lina Baranauskienė, Daumantas Matulis, John O. Trent, Jonathan B. Chaires	10
6	The solution structures of higher-order human telomere G-quadruplex multimers 2021 ·Nucleic Acids Research ·Robert C. Monsen, Srinivas Chakravarthy, William L. Dean, Jonathan B. Chaires, John O. Trent	35
7	Human POT1 unfolds G-quadruplexes by conformational selection 2020 ·Nucleic Acids Research ·Jonathan B. Chaires, Robert D. Gray, William L. Dean, Robert C. Monsen, Lynn DeLeeuw, Vilius Stribinskis, John O. Trent	30
8	Solution structure and functional investigation of human guanylate kinase reveals allosteric networking and a crucial role for the enzyme in cancer 2019 ·Journal of Biological Chemistry ·(unknown), Parag P. Shah, David Ban, Pablo Trigo‐Mouriño, (unknown), Lynn DeLeeuw, William L. Dean, John O. Trent, Levi J. Beverly, Manfred Konrad, (unknown), T. Michael Sabo	16
9	Folding Landscape of a Parallel G-Quadruplex 2019 ·The Journal of Physical Chemistry Letters ·Robert D. Gray, John O. Trent, Sengodagounder Arumugam, Jonathan B. Chaires	36
10	G-quadruplex oligonucleotide AS1411 as a cancer-targeting agent: Uses and mechanisms General subjects 2017 ·Biochimica et Biophysica Acta ·Paula J. Bates, Elsa M. Reyes‐Reyes, Mohammad Tariq Malik, Emily Murphy, Martin G. O’Toole, John O. Trent	3
11	G‐Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy 2017 ·Angewandte Chemie ·Rafael del Villar‐Guerra, John O. Trent, Jonathan B. Chaires	55
12	G‐Quadruplex Secondary Structure Obtained from Circular Dichroism Spectroscopy breakdown → 2017 ·Angewandte Chemie International Edition ·Rafael del Villar‐Guerra, John O. Trent, Jonathan B. Chaires	403
13	Targeting the Nuclear Import Receptor Kpnβ1 as an Anticancer Therapeutic 2016 ·Molecular Cancer Therapeutics ·Pauline J. van der Watt, (unknown), (unknown), (unknown), (unknown), Sarah Carden, Liselotte Angus, Kate Hadley, Dirk Lang, Wei Wei, Michael J. Birrer, John O. Trent, Virna D. Leaner	59
14	Aptamer imaging with Cu-64 labeled AS1411: Preliminary assessment in lung cancer 2013 ·Nuclear Medicine and Biology ·Junling Li, Huaiyu Zheng, Paula J. Bates, (unknown), Xiao‐Feng Li, John O. Trent, Chin K. Ng	61
15	Effect of O ⁶ -Methylguanine on the Stability of G-Quadruplex DNA 2008 ·Journal of the American Chemical Society ·Chongkham S. Mekmaysy, Luigi Petraccone, Nichola C. Garbett, Patricia A. Ragazzon, Robert D. Gray, John O. Trent, Jonathan B. Chaires	54
16	A Novel, Macrophage Migration Inhibitory Factor Suicide Substrate Inhibits Motility and Growth of Lung Cancer Cells 2008 ·Cancer Research ·(unknown), (unknown), Swen Zierow, Beatriz E. Rendon, G.V. Crichlow, (unknown), Richard Bucala, Lin Leng, Ned B. Smith, Elias Lolis, John O. Trent, Robert A. Mitchell	133
17	Structural studies of CXCR4, an antimetastatic target 2004 ·Cancer Research ·John O. Trent, Zixuan Wang, James L. Murray, Wen-Hai Shao, Hirokazu Tamamura, (unknown), Stephen C. Peiper	1
18	Identification of the p16-Arc Subunit of the Arp 2/3 Complex as a Substrate of MAPK-activated Protein Kinase 2 by Proteomic Analysis 2003 ·Journal of Biological Chemistry ·Saurabh Singh, David W. Powell, Madhavi J. Rane, Tom H. Millard, John O. Trent, William M. Pierce, Jon B. Klein, Laura M. Machesky, Kenneth R. McLeish	48
19	Molecular modeling of drug-DNA complexes: An update 2001 ·Methods in enzymology on CD-ROM/Methods in enzymology ·John O. Trent	12
20	Antiproliferative Activity of G-rich Oligonucleotides Correlates with Protein Binding 1999 ·Journal of Biological Chemistry ·Paula J. Bates, J B Kahlon, Shelia D. Thomas, John O. Trent, Donald M. Miller	327

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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