Lawrence MacPherson

1.3k citations

21 papers · 868 indexed · h-index 13

Impact in

Cancer Research top 5%
- Protease and Inhibitor Mechanisms
- Cancer, Lipids, and Metabolism
Oncology top 10%
- Peptidase Inhibition and Analysis

Papers in ⓘ

Hematology 3
- Platelet Disorders and Treatments 2
Pharmacy 1

Co-authors: Michelle Palmer (11 shared papers)Stuart L. Schreiber (11 shared papers)Joshua A. Bittker (6 shared papers)Sivaraman Dandapani (6 shared papers)David T. Parker (2 shared papers)Benito Muñoz (4 shared papers)Vishwas Ganu (3 shared papers)V. Blancuzzi (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (4 papers)Inflammation Research (2 papers)ACS Medicinal Chemistry Letters (2 papers)Journal of Medicinal Chemistry (2 papers)Tetrahedron Letters (1 paper)
Partner nations: United States Switzerland Sweden

In The Last Decade

Lawrence MacPherson

21 papers receiving 823 citations

Peers

Countries citing papers authored by Lawrence MacPherson

Since Specialization

Citations

This map shows the geographic impact of Lawrence MacPherson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence MacPherson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence MacPherson more than expected).

Fields of papers citing papers by Lawrence MacPherson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence MacPherson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence MacPherson. The network helps show where Lawrence MacPherson may publish in the future.

Co-authors

The 25 scholars most cited alongside Lawrence MacPherson, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lawrence MacPherson Line = papers co-authored together Lawrence MacPherson links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

Showing the 20 most-cited of 21 papers — load more, or switch the sort, to bring in the rest.

#	Work
1	Discovery of CGS 27023A, a Non-Peptidic, Potent, and Orally Active Stromelysin Inhibitor That Blocks Cartilage Degradation in Rabbits Journal of Medicinal Chemistry ·Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli, Brian J. Carroll, R Goldstein, Michael R. Justice, Lijuan Zhu, Shou‐Ih Hu, Richard Melton, Lynn R. Fryer, Ron L. Goldberg, John Doughty, S. Spirito, V. Blancuzzi, Doug Wilson, Elizabeth O’Byrne, Vishwas Ganu, David T. Parker	1997	288
2	Development of small-molecule probes that selectively kill cells induced to express mutant RAS Bioorganic & Medicinal Chemistry Letters ·Michel Weïwer, Joshua A. Bittker, Timothy A. Lewis, Kaoru Shimada, Wan Seok Yang, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Brent R. Stockwell, Stuart L. Schreiber, Benito Muñoz	2011	181
3	Inhibitors of poly ADP-ribose polymerase (PARP) induce apoptosis of myeloid leukemic cells: potential for therapy of myeloid leukemia and myelodysplastic syndromes Haematologica ·Terry J. Gaymes, Sydney Shall, Lawrence MacPherson, Natalie A. Twine, N C Lea, Farzin Farzaneh, G J Mufti	2009	64
4	Natural Selection, Protein Engineering, and the Last Riboorganism: Rational Model Building in Biochemistry Cold Spring Harbor Symposia on Quantitative Biology ·Steven A. Benner, Rudolf K. Allemann, Andrew D. Ellington, Liang Ge, Arthur Glasfeld, G F Leanz, Tilman Krauch, Lawrence MacPherson, Simon E. Moroney, Joseph A. Piccirilli, (unknown)	1987	58
5	Potent and selective inhibitors of Helicobacter pylori glutamate racemase (MurI): Pyridodiazepine amines Bioorganic & Medicinal Chemistry Letters ·Bolin Geng, Gregory S. Basarab, Janelle Comita-Prevoir, Madhusudhan Gowravaram, Pamela Hill, Andrew F. Kiely, James T. Loch, Lawrence MacPherson, Marshall Morningstar, G. B. MULLEN, Ekundayo Osimboni, Alexander L. Satz, Charles J. Eyermann, T. Lundqvist	2008	39
6	A Direct Route to 3‐(D‐Ribofuranosyl)pyridine Nucleosides Helvetica Chimica Acta ·Joseph A. Piccirilli, Tilman Krauch, Lawrence MacPherson, Steven A. Benner	1991	36
7	Macrocycles in the construction of acyclic stereochemistry Tetrahedron ·W. Clark Still, Lawrence MacPherson, Toshiro Harada, James F. Callahan, Arnold L. Rheingold	1984	34
8	Discovery of 1,3-Diaminobenzenes as Selective Inhibitors of Platelet Activation at the PAR1 Receptor ACS Medicinal Chemistry Letters ·Chris Dockendorff, Omozuanvbo Aisiku, Lynn VerPlank, James R. Dilks, Daniel A. Smith, Susanna F. Gunnink, Louisa Dowal, Joseph Negri, Michelle Palmer, Lawrence MacPherson, Stuart L. Schreiber, Robert Flaumenhaft	2012	33
9	Macrocyclic Hedgehog Pathway Inhibitors: Optimization of Cellular Activity and Mode of Action Studies ACS Medicinal Chemistry Letters ·Chris Dockendorff, M. Marek Nagiec, Michel Weïwer, Sara J. Buhrlage, Amal Ting, Partha P. Nag, Andrew Germain, Han‐Je Kim, Willmen Youngsaye, Christina Scherer, Melissa Bennion, Linlong Xue, Benjamin Z. Stanton, Timothy A. Lewis, Lawrence MacPherson, Michelle Palmer, Michael A. Foley, José R. Perez, Stuart L. Schreiber	2012	30
10	Oral administration of a matrix metalloproteinase inhibitor, CGS 27023A, protects the cartilage proteoglycan matrix in a partial meniscectomy model of osteoarthritis in rabbits Inflammation Research ·E. M. O’Byrne, David T. Parker, E. D. Roberts, Ronald Goldberg, Lawrence MacPherson, V. Blancuzzi, Douglas E. Wilson, H. N. Singh, R Ludewig, Vishwas Ganu	1995	25
11	Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor Journal of Medicinal Chemistry ·Lawrence MacPherson, Erol K. Bayburt, Michael Capparelli, Regine S. Bohacek, Frank H. Clarke, Rajendra D. Ghai, Yumi Sakane, Carol Berry, Jane Peppard, Angelo J. Trapani	1993	22
12	Piperazinyl quinolines as chemosensitizers to increase fluconazole susceptibility of Candida albicans clinical isolates Bioorganic & Medicinal Chemistry Letters ·Willmen Youngsaye, Benjamin Vincent, Cathy L Hartland, Barbara J. Morgan, Sara J. Buhrlage, Stephen Johnston, Joshua A. Bittker, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Luke Whitesell, Susan Lindquist, Stuart L. Schreiber, Benito Muñoz	2011	15
13	Identification of small-molecule inhibitors of Trypansoma cruzi replication Bioorganic & Medicinal Chemistry Letters ·Andrew Germain, Leigh Carmody, Chris Dockendorff, Cristina Galan-Rodriguez, Ana Rodrı́guez, Stephen Johnston, Joshua A. Bittker, Lawrence MacPherson, Sivaraman Dandapani, Michelle Palmer, Stuart L. Schreiber, Benito Muñoz	2011	13
14	Electrochemical transcarbonation: Hydroquinoxy carbonyl protecting group for alcohols and amines Tetrahedron Letters ·Richard Johnson, Edward R. Grover, Lawrence MacPherson	1981	7
15	Identification of a small molecule that selectively inhibits alpha-synuclein translational expression Europe PMC (PubMed Central) ·Nathan T. Ross, Shailesh Metkar, Hanh Le, Jason Burbank, Catherine M. Cahill, Andrew Germain, Lawrence MacPherson, Joshua A. Bittker, Michelle Palmer, Jack T. Rogers, Stuart L. Schreiber	2011	7
16	Intra-articular injection of stromelysin into rabbit knees as a model to evaluate matrix metalloprotease inhibitors Inflammation Research ·Ronald Goldberg, David Parker, Lawrence MacPherson, Vishwas Ganu, Richard Melton, S Hu, V. Blancuzzi, Douglas E. Wilson, John Doughty, S. Spirito, E. M. O’Byrne	1995	4
17	Screen for RAS-Selective Lethal Compounds and VDAC Ligands - Probe 1 Joshua A. Bittker, Michel Weïwer, Kenichi Shimada, Wan Seok Yang, Lawrence MacPherson, Sivaraman Dandapani, Ben Munoz, Michelle Palmer, Brent R. Stockwell, Stuart L. Schreiber	2011	4
18	Chemical Genetic Analysis of Platelet Granule Secretion-Probe 1 Lynn VerPlank, Chris Dockendorff, Joseph Negri, José R. Perez, James R. Dilks, Lawrence MacPherson, Michelle Palmer, Robert Flaumenhaft, Stuart L. Schreiber	2011	3
19	Identification of small molecules that selectively inhibit fluconazole-resistant Candida albicans in the presence of fluconazole but not in its absence - Probe 2 Cathy L Hartland, Willmen Youngsaye, Barbara J. Morgan, Amal Ting, Partha P. Nag, Sara J. Buhrlage, Stephen Johnston, Joshua A. Bittker, Benjamin Vincent, Luke Whitesell, Sivaraman Dandapani, Lawrence MacPherson, Benito Muñoz, Michelle Palmer, Susan Lindquist, Stuart L. Schreiber	2011	2
20	Identification of Small Molecule Inhibitors that Suppress Cytokine-Induced Apoptosis in Human Pancreatic Islet Cells Europe PMC (PubMed Central) ·Patrick W. Faloon, Danny Hung‐Chieh Chou, Erin M. Forbeck, Deepika Walpita, Barbara J. Morgan, Sara J. Buhrlage, Amal Ting, José R. Perez, Lawrence MacPherson, Jeremy R. Duvall, Sivaraman Dandapani, Lisa A. Marcaurelle, Ben Munoz, Michelle Palmer, Michael A. Foley, Bridget K. Wagner, Stuart L. Schreiber	2011	2

About Lawrence MacPherson

Lawrence MacPherson is a scholar working on Hematology, Pharmacy, Cancer Research, Rheumatology and Immunology and Allergy, having authored 21 papers that have together received 868 indexed citations. Recurring topics across this work include Osteoarthritis Treatment and Mechanisms (3 papers), Knee injuries and reconstruction techniques (2 papers), Antifungal resistance and susceptibility (2 papers), Platelet Disorders and Treatments (2 papers), Protease and Inhibitor Mechanisms (2 papers), Trypanosoma species research and implications (2 papers), Antimicrobial Peptides and Activities (1 paper) and Asymmetric Synthesis and Catalysis (1 paper). The work is most often cited by research in Cancer Research (324 citations), Oncology (301 citations), Hematology (86 citations), Molecular Biology (510 citations) and Organic Chemistry (173 citations). Lawrence MacPherson has collaborated with scholars based in United States, Switzerland and Sweden. Frequent co-authors include Michelle Palmer, Stuart L. Schreiber, Joshua A. Bittker, Sivaraman Dandapani, David T. Parker, Benito Muñoz, Vishwas Ganu, V. Blancuzzi, Michael Capparelli and Erol K. Bayburt. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Inflammation Research, ACS Medicinal Chemistry Letters, Journal of Medicinal Chemistry and Tetrahedron Letters.

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