Joseph A. Piccirilli

9.5k citations

173 papers · 7.1k indexed · 2 hit papers · h-index 46

Co-authors: Nan‐Sheng Li Daniel Herschlag Thomas R. Cech John K. Frederiksen Simon E. Moroney Erik J. Sontheimer Peter M. Gordon Tilman Krauch
Topics: RNA and protein synthesis mechanisms (122 papers)RNA modifications and cancer (72 papers)DNA and Nucleic Acid Chemistry (69 papers)
Cited by: Molecular Biology Organic Chemistry Ecology
Journals: Nature Science Proceedings of the National Academy of Sciences
Partner nations: United States United Kingdom Switzerland

In The Last Decade

Joseph A. Piccirilli

170 papers receiving 7.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Enzymatic incorporation of a new base pair into DNA and RNA extends the genetic alphabet

1990 521 citations Joseph A. Piccirilli et al. profile →
Hachimoji DNA and RNA: A genetic system with eight building blocks

2019 330 citations Shuichi Hoshika, Nicole A. Leal et al. Science profile →

Peers

Countries citing papers authored by Joseph A. Piccirilli

Since Specialization

Citations

This map shows the geographic impact of Joseph A. Piccirilli's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Joseph A. Piccirilli with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Joseph A. Piccirilli more than expected).

Fields of papers citing papers by Joseph A. Piccirilli

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Joseph A. Piccirilli. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Joseph A. Piccirilli. The network helps show where Joseph A. Piccirilli may publish in the future.

Co-authorship network of co-authors of Joseph A. Piccirilli

This figure shows the co-authorship network connecting the top 25 collaborators of Joseph A. Piccirilli. A scholar is included among the top collaborators of Joseph A. Piccirilli based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Joseph A. Piccirilli. Joseph A. Piccirilli is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Genome-wide profiling of tRNA modifications by Induro-tRNAseq reveals coordinated changes 2025 ·Nature Communications ·Yuko Nakano,Howard Gamper,(unknown),(unknown),Jiatong Li,Zhiyi Sun,Erbay Yigit,Sebastian Grünberg,Keerthana Krishnan,Nan‐Sheng Li,Joseph A. Piccirilli,Ralph E. Kleiner,Nicole M. Nichols,Brian D. Gregory,Ya‐Ming Hou	2
2	Post-transcriptional methylation of mitochondrial-tRNA differentially contributes to mitochondrial pathology 2024 ·Nature Communications ·(unknown),Howard Gamper,(unknown),Thomas Christian,Robert Y. Henley,Nan‐Sheng Li,Takeo Suzuki,Tsutomu Suzuki,Joseph A. Piccirilli,Meni Wanunu,Erin L. Seifert,Douglas C. Wallace,Ya‐Ming Hou	0
3	The Role of General Acid Catalysis in the Mechanism of an Alkyl Transferase Ribozyme 2024 ·ACS Catalysis ·Timothy J. Wilson,(unknown),Şölen Ekesan,Timothy J. Giese,Nan‐Sheng Li,Lin Huang,Joseph A. Piccirilli,Darrin M. York,David M.J. Lilley	5
4	Crystal structure of a cap-independent translation enhancer RNA 2023 ·Nucleic Acids Research ·(unknown),(unknown),(unknown),(unknown),Phoebe A. Rice,Joseph A. Piccirilli	6
5	Sub-3-Å cryo-EM structure of RNA enabled by engineered homomeric self-assembly 2022 ·Nature Methods ·Di Liu,(unknown),Joseph A. Piccirilli,Maofu Liao,Peng Yin	36
6	Structures of artificially designed discrete RNA nanoarchitectures at near-atomic resolution 2021 ·Science Advances ·Di Liu,Yaming Shao,Joseph A. Piccirilli,Yossi Weizmann	3
7	Branched kissing loops for the construction of diverse RNA homooligomeric nanostructures 2020 ·Nature Chemistry ·Di Liu,Cody Geary,Gang Chen,Yaming Shao,Mo Li,Chengde Mao,Ebbe Sloth Andersen,Joseph A. Piccirilli,Paul W. K. Rothemund,Yossi Weizmann	53
8	A conserved RNA structural motif for organizing topology within picornaviral internal ribosome entry sites 2019 ·Nature Communications ·Deepak Koirala,Yaming Shao,Yelena Koldobskaya,James R. Fuller,Andrew M. Watkins,Sandip A. Shelke,Evgeny V. Pilipenko,Rhiju Das,Phoebe A. Rice,Joseph A. Piccirilli	18
9	Hachimoji DNA and RNA: A genetic system with eight building blocksbreakdown → 2019 ·Science ·Shuichi Hoshika,Nicole A. Leal,Myong‐Jung Kim,Myong‐Sang Kim,Nilesh B. Karalkar,Hyo‐Joong Kim,Alison M. Bates,(unknown),(unknown),Adam J. Meyer,Saurja DasGupta,Joseph A. Piccirilli,Andrew D. Ellington,John SantaLucia,Millie M. Georgiadis,Steven A. Benner	330
10	Prolactin Receptor–Mediated Internalization of Imaging Agents Detects Epithelial Ovarian Cancer with Enhanced Sensitivity and Specificity 2017 ·Cancer Research ·Karthik M. Sundaram,Yilin Zhang,Anirban Mitra,(unknown),Katja Gwin,Anthony A. Kossiakoff,Brian B. Roman,Ernst Lengyel,Joseph A. Piccirilli	14
11	Kinetic Isotope Effect Analysis of RNA 2′- O -Transphosphorylation 2017 ·Methods in enzymology on CD-ROM/Methods in enzymology ·Michael E. Harris,Darrin M. York,Joseph A. Piccirilli,Vernon Anderson	3
12	Experimental and computational analysis of the transition state for ribonuclease A-catalyzed RNA 2′- O -transphosphorylation 2013 ·Proceedings of the National Academy of Sciences ·Hong Gu,Shuming Zhang,K. Y. Wong,Brian K. Radak,(unknown),(unknown),Qing Dai,Masaru Miyagi,Vernon Anderson,Darrin M. York,Joseph A. Piccirilli,Michael E. Harris	59
13	Recognition of guanosine by dissimilar tRNA methyltransferases 2012 ·RNA ·Reiko Sakaguchi,(unknown),Qing Dai,(unknown),Zita Liutkevičiūtė,Saulius Klimašauskas,Joseph A. Piccirilli,Finn Kirpekar,Ya‐Ming Hou	28
14	Nucleobase-mediated general acid-base catalysis in the Varkud satellite ribozyme 2010 ·Proceedings of the National Academy of Sciences ·Timothy J. Wilson,Nan‐Sheng Li,Jun Lu,John K. Frederiksen,Joseph A. Piccirilli,David M.J. Lilley	64
15	The 2.5 Å Structure of CD1c in Complex with a Mycobacterial Lipid Reveals an Open Groove Ideally Suited for Diverse Antigen Presentation 2010 ·Immunity ·Louise Scharf,Nan‐Sheng Li,(unknown),(unknown),Tejia Zhang,Lisa Fox,(unknown),(unknown),Esmael J. Haddadian,Jenny E. Gumperz,Alan Saghatelian,José D. Faraldo‐Gómez,Stephen C. Meredith,Joseph A. Piccirilli,Erin J. Adams	90
16	Crystal Structure of the Catalytic Core of an RNA-Polymerase Ribozyme 2009 ·Science ·David M Shechner,Robert A. Grant,Sarah C. Bagby,Yelena Koldobskaya,Joseph A. Piccirilli,David P. Bartel	100
17	Synthesis of Pyridine, Pyrimidine and Pyridinone C -Nucleoside Phosphoramidites for Probing Cytosine Function in RNA 2009 ·The Journal of Organic Chemistry ·Jun Lu,Nan‐Sheng Li,Selene C. Koo,Joseph A. Piccirilli	24
18	Structural inference of native and partially folded RNA by high-throughput contact mapping 2008 ·Proceedings of the National Academy of Sciences ·Rhiju Das,(unknown),Magdalena Jonikas,Alain Laederach,Robert Fong,Jason P. Schwans,David Baker,Joseph A. Piccirilli,Russ B. Altman,Daniel Herschlag	72
19	Synthetic antibodies for specific recognition and crystallization of structured RNA 2007 ·Proceedings of the National Academy of Sciences ·Jing‐Dong Ye,Valentina Tereshko,John K. Frederiksen,Akiko Koide,Frédéric A. Fellouse,Sachdev S. Sidhu,Shohei Koide,Anthony A. Kossiakoff,Joseph A. Piccirilli	111
20	6 How the Group I Intron Works: A Case Study of RNA Structure and Function 2006 ·Cold Spring Harbor Monograph Archive ·James L. Hougland,Joseph A. Piccirilli,Marcello Forconi,(unknown),Daniel Herschlag	42

About Joseph A. Piccirilli

Joseph A. Piccirilli is a scholar working on Molecular Biology, Infectious Diseases and Structural Biology, having authored 173 papers that have together received 7.1k indexed citations. Recurring topics across this work include RNA and protein synthesis mechanisms (122 papers), RNA modifications and cancer (72 papers) and DNA and Nucleic Acid Chemistry (69 papers). The work is most often cited by research in Molecular Biology (6.1k citations), Organic Chemistry (771 citations) and Ecology (521 citations). Joseph A. Piccirilli has collaborated with scholars based in United States, United Kingdom and Switzerland. Frequent co-authors include Nan‐Sheng Li, Daniel Herschlag, Thomas R. Cech, John K. Frederiksen, Simon E. Moroney, Erik J. Sontheimer, Peter M. Gordon, Tilman Krauch, Qing Dai and Sengen Sun. Their work appears in journals such as Nature, Science and Proceedings of the National Academy of Sciences.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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