Lance P. Encell

7.7k citations

34 papers · 5.2k indexed · 3 hit papers · h-index 21

Impact in

Biophysics top 0.2%
- Advanced Fluorescence Microscopy Techniques
Structural Biology top 2%

Papers in

Molecular Biology 31
- bioluminescence and chemiluminescence research 12
- DNA Repair Mechanisms 6
- Epigenetics and DNA Methylation 6
- Advanced biosensing and bioanalysis techniques 6
- CRISPR and Genetic Engineering 6
Biophysics 2

Co-authors: Keith V. Wood Monika G. Wood Paul Otto Kris Zimmerman Mary P. Hall Thomas Machleidt Brock F. Binkowski Gediminas Vidugiris
Journals: ACS Chemical Biology (7 papers)Carcinogenesis (3 papers)Nature Biotechnology (2 papers)Chemical Research in Toxicology (2 papers)PLoS ONE (2 papers)
Partner nations: United States Netherlands Switzerland

In The Last Decade

Lance P. Encell

34 papers receiving 5.1k citations

Hit Papers

align trajectories log scale

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells 2015 · 904 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2015 ACS Chemical Biology
2012 ACS Chemical Biology
2008 ACS Chemical Biology

Peers

Countries citing papers authored by Lance P. Encell

Since Specialization

Citations

This map shows the geographic impact of Lance P. Encell's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lance P. Encell with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lance P. Encell more than expected).

Fields of papers citing papers by Lance P. Encell

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lance P. Encell. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lance P. Encell. The network helps show where Lance P. Encell may publish in the future.

Co-authors

The 25 scholars most cited alongside Lance P. Encell, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lance P. Encell Line = papers co-authored together Lance P. Encell links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	An optimized bioluminescent substrate for non-invasive imaging in the brain Nature Chemical Biology ·Yichi Su, Joel R. Walker, Mary P. Hall, Mark A. Klein, Xiang Wu, Lance P. Encell, Kerriann M. Casey, 章允三上, Guosong Hong, Michael Z. Lin, Thomas A. Kirkland	2023	38
2	Development of a rapid, simple, and sensitive point-of-care technology platform utilizing ternary NanoLuc Frontiers in Microbiology ·Shao Fei Wang, Julia L. Riera, S. M. Zahorulko, Robin Hurst, Mary P. Hall, Lance P. Encell, Thomas Boehringer, D. Lee, William M. Rehrauer, Molly A. Accola, G. Lupfer, Thomas Machleidt, Melanie L. Dart	2022	3
3	Simple, Rapid Chemical Labeling and Screening of Antibodies with Luminescent Peptides ACS Chemical Biology ·S. M. Zahorulko, Hui Wang, H P George, Shao Fei Wang, Julia L. Riera, Michel Hottelier, Mary P. Hall, Robin Hurst, Monika G. Wood, Julia Gilden, Thomas A. Kirkland, Dan Lazar, G. Lupfer, Lance P. Encell, Thomas Machleidt, Wenhui Zhou, Melanie L. Dart	2022	3
4	Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals Nature Methods ·Yichi Su, Joel R. Walker, Yun‐Hee Park, Thomas P. Smith, 章允三上, Mary P. Hall, Louai Labanieh, Robin Hurst, David C. Wang, Lance P. Encell, Namdoo Kim, Feijie Zhang, Mark A. Kay, Kerriann M. Casey, Robbie G. Majzner, Jennifer R. Cochran, Crystal L. Mackall, Thomas A. Kirkland, Michael Z. Lin	2020	128
5	Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging Molecular Imaging and Biology ·Giorgia Zambito, Guangjian Chen, Yanto Ridwan, Mary P. Hall, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Clemens W.G.M. Löwik, Laura Mezzanotte	2020	21
6	Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging iScience ·Giorgia Zambito, Mary P. Hall, Monika G. Wood, Guangjian Chen, Yanto Ridwan, Fabio Stellari, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Nunut Hutabarat, Laura Mezzanotte	2020	32
7	5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems PLoS ONE ·Ce Shi, 解震 XIE Zhen, Mary P. Hall, Paul Otto, Monika G. Wood, Kaichao Shao, Lance P. Encell, Thomas Machleidt, Keith V. Wood, Thomas A. Kirkland	2020	1
8	Utilizing a Simple Method for Stoichiometric Protein Labeling to Quantify Antibody Blockade Scientific Reports ·Rachel Friedman Ohana, Robin Hurst, Jakob Luyckx, Sergiy Levin, Thomas Machleidt, Thomas A. Kirkland, Lance P. Encell, Matthew B. Robers, Keith V. Wood	2019	9
9	Click beetle luciferase mutant and near infrared naphthyl-luciferins for improved bioluminescence imaging Nature Communications ·Mary P. Hall, Carolyn C. Woodroofe, Monika G. Wood, Ivo Que, Bian Ran, Yanto Ridwan, Ce Shi, Thomas A. Kirkland, Lance P. Encell, Keith V. Wood, Clemens W.G.M. Löwik, Laura Mezzanotte	2018	110
10	NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells ACS Chemical Biology ·Andrew S. Dixon, Marie K. Schwinn, Mary P. Hall, Kris Zimmerman, Paul Otto, Thomas Lübben, Braeden L. Butler, Brock F. Binkowski, Thomas Machleidt, Thomas A. Kirkland, Monika G. Wood, Christopher T. Eggers, Lance P. Encell, Keith V. Wood Hit paper breakdown →	2015	904
11	Imaging Proteolytic Activity in Live Cells and Animal Models PLoS ONE ·Stefanie Galbán, Yong Hyun Jeon, Brittany M. Bowman, James Stevenson, Christi Spain-Savage, Lisa M. Sharkey, Michael J. Lafferty, Benjamin A. Hoff, Braeden L. Butler, Taeck-Sung Jeong, Brock F. Binkowski, Paul Otto, Kris Zimmerman, Gediminas Vidugiris, Lance P. Encell, Frank Fan, Keith V. Wood, Craig J. Galbán, Brian D. Ross, Alnawaz Rehemtulla	2013	29
12	Development of a Dehalogenase-Based Protein Fusion Tag Capable of Rapid, Selective and Covalent Attachment to Customizable Ligands PubMed ·Lance P. Encell	2012	107
13	HaloTag7: A genetically engineered tag that enhances bacterial expression of soluble proteins and improves protein purification Protein Expression and Purification ·Rachel Friedman Ohana, Lance P. Encell, Kate Zhao, Dan Simpson, Michael R. Slater, Marjeta Urh, Keith V. Wood	2009	126
14	HaloTag: A Novel Protein Labeling Technology for Cell Imaging and Protein Analysis ACS Chemical Biology ·Georgyi V. Los, Lance P. Encell, Mark G. McDougall, I. V. Fadeyeva, Natasha Karassina, Chad Zimprich, Monika G. Wood, Alka Rani, Rachel Friedman Ohana, Marjeta Urh, Dan Simpson, Jacqui Méndez, Kris Zimmerman, Paul Otto, Gediminas Vidugiris, Ji Zhu, Aldis Darzins, Dieter H. Klaubert, Robert F. Bulleit, Keith V. Wood Hit paper breakdown →	2008	1810
15	Growth factor engineering by degenerate homoduplex gene family recombination Nature Biotechnology ·Wayne M. Coco, Lance P. Encell, William E. Levinson, И.А. Шанин, A. Katrina Loomis, Laura L. Licato, Joseph J. Arensdorf, Marc Loesch, Philip T. Pienkos, Daniel J. Monticello	2002	44
16	Human O6 -alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes Carcinogenesis ·Nieves Abril, Blust Lc, Fred C. Christians, Lance P. Encell, Lawrence A. Loeb, Carmen Pueyo	1999	14
17	Improving enzymes for cancer gene therapy Nature Biotechnology ·Lance P. Encell, Daniel M. Landis, Lawrence A. Loeb	1999	59
18	Creating novel enzymes by applied molecular evolution Chemistry & Biology ·Adonis Skandalis, Lance P. Encell, Lawrence A. Loeb	1997	34
19	The relationship between N-nitrosodimethylamine metabolism and DNA methylation in isolated rat hepatocytes Carcinogenesis ·Lance P. Encell, Peter G. Foiles, Barry Gold	1996	8
20	The Design of Agents To Control DNA Methylation Adducts. Enhanced Major Groove Methylation of DNA by an N-Methyl-N-nitrosourea Functionalized Phenyl Neutral Red Intercalator Chemical Research in Toxicology ·Yama Afghanyar, Fang‐Ju Chou, Jonathan Williams, Anna Kholifahtul Janah, Lance P. Encell, David E. G. Shuker, Barry Gold	1996	8

About Lance P. Encell

Lance P. Encell is a scholar working on Molecular Biology, Biophysics, Cellular and Molecular Neuroscience, Biotechnology and Endocrinology, having authored 34 papers that have together received 5.2k indexed citations. Recurring topics across this work include bioluminescence and chemiluminescence research (12 papers), DNA Repair Mechanisms (6 papers), Epigenetics and DNA Methylation (6 papers), Advanced biosensing and bioanalysis techniques (6 papers), CRISPR and Genetic Engineering (6 papers), Photoreceptor and optogenetics research (5 papers), Biosensors and Analytical Detection (5 papers) and Click Chemistry and Applications (4 papers). The work is most often cited by research in Biophysics (740 citations), Structural Biology (101 citations), Molecular Biology (4.0k citations), Cellular and Molecular Neuroscience (641 citations) and Cell Biology (537 citations). Lance P. Encell has collaborated with scholars based in United States, Netherlands and Switzerland. Frequent co-authors include Keith V. Wood, Monika G. Wood, Paul Otto, Kris Zimmerman, Mary P. Hall, Thomas Machleidt, Brock F. Binkowski, Gediminas Vidugiris, Christopher T. Eggers and Dieter H. Klaubert. Their work appears in journals such as ACS Chemical Biology, Carcinogenesis, Nature Biotechnology, Chemical Research in Toxicology and PLoS ONE.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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