Lawrence A. Loeb

37.3k total citations · 7 hit papers
356 papers, 28.6k citations indexed

About

Lawrence A. Loeb is a scholar working on Molecular Biology, Cancer Research and Genetics. According to data from OpenAlex, Lawrence A. Loeb has authored 356 papers receiving a total of 28.6k indexed citations (citations by other indexed papers that have themselves been cited), including 282 papers in Molecular Biology, 120 papers in Cancer Research and 76 papers in Genetics. Recurrent topics in Lawrence A. Loeb's work include DNA Repair Mechanisms (180 papers), DNA and Nucleic Acid Chemistry (90 papers) and Cancer Genomics and Diagnostics (61 papers). Lawrence A. Loeb is often cited by papers focused on DNA Repair Mechanisms (180 papers), DNA and Nucleic Acid Chemistry (90 papers) and Cancer Genomics and Diagnostics (61 papers). Lawrence A. Loeb collaborates with scholars based in United States, Israel and Japan. Lawrence A. Loeb's co-authors include Bradley D. Preston, Thomas A. Kunkel, Jesse J. Salk, Michael Fry, Aimee L. Jackson, Keith R. Loeb, Keith C. Cheng, Hiroshi Kasai, Edward Fox and Ashwini S. Kamath‐Loeb and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Lawrence A. Loeb

353 papers receiving 27.4k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

8-Hydroxyguanine, an abundant form of oxidative DNA damage, causes G-T and A-C substitutions.

1992 1.5k citations Lawrence A. Loeb et al. profile →
MUTAGENESIS BY APURINIC/APYRIMIDINIC SITES

1986 800 citations Lawrence A. Loeb, Bradley D. Preston profile →
Detection of ultra-rare mutations by next-generation sequencing

2012 727 citations Michael W. Schmitt, Scott R. Kennedy et al. Proceedings of the National Academy of Sciences profile →
Fidelity of HIV-1 Reverse Transcriptase

1988 688 citations Bradley D. Preston, Lawrence A. Loeb et al. profile →
Multiple mutations and cancer

2003 549 citations Lawrence A. Loeb, Keith R. Loeb et al. Proceedings of the National Academy of Sciences profile →
A Mutator Phenotype in Cancer 1

2001 533 citations Lawrence A. Loeb profile →
Enhancing the accuracy of next-generation sequencing for detecting rare and subclonal mutations

2018 337 citations Jesse J. Salk, Michael W. Schmitt et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Lawrence A. Loeb United States	86	20.4k	7.5k	4.8k	3.8k	2.6k	356	28.6k
Samuel H. Wilson United States	93	25.2k 1.2×	4.0k 0.5×	3.2k 0.7×	4.6k 1.2×	1.4k 0.5×	500	29.3k
Tomas Lindahl Sweden	101	32.3k 1.6×	8.2k 1.1×	5.1k 1.1×	7.0k 1.8×	2.0k 0.8×	364	42.7k
Arthur B. Pardee United States	89	23.1k 1.1×	3.5k 0.5×	4.8k 1.0×	6.2k 1.7×	873 0.3×	361	32.7k
William S. Lane United States	92	28.0k 1.4×	6.8k 0.9×	4.0k 0.8×	5.5k 1.5×	1.2k 0.5×	201	36.8k
Thomas A. Kunkel United States	113	42.0k 2.1×	8.4k 1.1×	9.1k 1.9×	5.6k 1.5×	8.6k 3.3×	405	51.9k
Zbigniew Darżynkiewicz United States	96	22.5k 1.1×	4.6k 0.6×	2.4k 0.5×	7.0k 1.9×	1.8k 0.7×	651	37.0k
George R. Stark United States	112	27.8k 1.4×	7.3k 1.0×	5.3k 1.1×	20.9k 5.6×	2.3k 0.9×	349	54.9k
Geoffrey M. Wahl United States	80	21.7k 1.1×	4.8k 0.6×	4.3k 0.9×	11.1k 3.0×	1.1k 0.4×	178	30.1k
Julian Adams United States	69	14.2k 0.7×	2.4k 0.3×	2.3k 0.5×	6.2k 1.6×	1.6k 0.6×	168	21.4k
Ettore Appella United States	120	33.4k 1.6×	6.4k 0.9×	4.4k 0.9×	17.8k 4.7×	1.3k 0.5×	551	54.6k

Countries citing papers authored by Lawrence A. Loeb

Since Specialization

Citations

This map shows the geographic impact of Lawrence A. Loeb's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence A. Loeb with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence A. Loeb more than expected).

Fields of papers citing papers by Lawrence A. Loeb

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence A. Loeb. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence A. Loeb. The network helps show where Lawrence A. Loeb may publish in the future.

Co-authorship network of co-authors of Lawrence A. Loeb

This figure shows the co-authorship network connecting the top 25 collaborators of Lawrence A. Loeb. A scholar is included among the top collaborators of Lawrence A. Loeb based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lawrence A. Loeb. Lawrence A. Loeb is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Qin, Guangrong, Ilya Shmulevich, Taek‐Kyun Kim, et al.. (2020). Co-Occurring Mutation Clusters Predict Drug Sensitivity in Acute Myeloid Leukemia. Blood. 136(Supplement 1). 12–13.

Shen, Jiang-Cheng, Ashwini S. Kamath‐Loeb, Brendan F. Kohrn, et al.. (2019). A high-resolution landscape of mutations in the BCL6 super-enhancer in normal human B cells. Proceedings of the National Academy of Sciences. 116(49). 24779–24785. 16 indexed citations

Loeb, Lawrence A., Brendan F. Kohrn, Eun Hyun Ahn, et al.. (2019). Extensive subclonal mutational diversity in human colorectal cancer and its significance. Proceedings of the National Academy of Sciences. 116(52). 26863–26872. 37 indexed citations

Ratnakumar, Kajan, et al.. (2019). 748 Duplex sequencing reveals the effects of caffeine on reducing UV-induced mutations of cancer-relevant genes. Journal of Investigative Dermatology. 139(5). S129–S129. 1 indexed citations

Reid-Bayliss, Kate S. & Lawrence A. Loeb. (2017). Accurate RNA consensus sequencing for high-fidelity detection of transcriptional mutagenesis-induced epimutations. Proceedings of the National Academy of Sciences. 114(35). 9415–9420. 28 indexed citations

Ahn, Eun Hyun, et al.. (2016). Decreased Mitochondrial Mutagenesis during Transformation of Human Breast Stem Cells into Tumorigenic Cells. Cancer Research. 76(15). 4569–4578. 14 indexed citations

Schmitt, Michael W., Edward Fox, Marc J. Prindle, et al.. (2015). Sequencing small genomic targets with high efficiency and extreme accuracy. Nature Methods. 12(5). 423–425. 110 indexed citations

Kennedy, Scott R., Michael W. Schmitt, Edward Fox, et al.. (2014). Detecting ultralow-frequency mutations by Duplex Sequencing. Nature Protocols. 9(11). 2586–2606. 314 indexed citations

Schmitt, Michael W., Scott R. Kennedy, Jesse J. Salk, et al.. (2012). Detection of ultra-rare mutations by next-generation sequencing. Proceedings of the National Academy of Sciences. 109(36). 14508–14513. 727 indexed citations breakdown →

10.

Schmitt, Michael, Marc J. Prindle, & Lawrence A. Loeb. (2012). Implications of genetic heterogeneity in cancer. Annals of the New York Academy of Sciences. 1267(1). 110–116. 46 indexed citations

11.

Kennedy, Scott R., Lawrence A. Loeb, & Alan J. Herr. (2011). Somatic mutations in aging, cancer and neurodegeneration. Mechanisms of Ageing and Development. 133(4). 118–126. 159 indexed citations

12.

Salk, Jesse J., et al.. (2009). Optimization of DNA polymerase mutation rates during bacterial evolution. Proceedings of the National Academy of Sciences. 107(3). 1154–1159. 65 indexed citations

13.

Bielas, Jason H., Ranga N. Venkatesan, & Lawrence A. Loeb. (2007). LOH-proficient embryonic stem cells: a model of cancer progenitor cells?. Trends in Genetics. 23(4). 154–157. 10 indexed citations

14.

Camps, Manel, et al.. (2003). Targeted gene evolution in Escherichia coli using a highly error-prone DNA polymerase I. Proceedings of the National Academy of Sciences. 100(17). 9727–9732. 123 indexed citations

15.

Blank, A. & Lawrence A. Loeb. (1991). Isolation of temperature-sensitive DNA polymerase III from Saccharomyces cerevisiae cdc2-2. Biochemistry. 30(32). 8092–8096. 5 indexed citations

16.

Loeb, Lawrence A., Philip K. Liu, & Michael Fry. (1986). DNA Polymerase-α: Enzymology, Function, Fidelity, and Mutagenesis. Progress in nucleic acid research and molecular biology. 57–110. 25 indexed citations

17.

Loeb, Lawrence A.. (1979). Fidelity of dna replication. Cold Spring Harbor Symposia on Quantitative Biology. 89. 13 indexed citations

18.

Agarwal, Shyam S., et al.. (1977). Screening for deficits in DNA repair by the response of irradiated human lymphocytes to phytohemagglutinin.. PubMed. 37(10). 3594–8. 24 indexed citations

19.

Millman, Irving, Lawrence A. Loeb, M. E. Bayer, & Baruch S. Blumberg. (1970). AUSTRALIA ANTIGEN (A HEPATITIS-ASSOCIATED ANTIGEN). The Journal of Experimental Medicine. 131(6). 1190–1199. 54 indexed citations

20.

Kato, Ryuji, et al.. (1966). Studies on the Mechanism of Drug-Induced Microsomal Enzyme Activities. Molecular Pharmacology. 2(2). 171–186. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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