Thomas A. Kirkland

4.3k citations

43 papers · 2.7k indexed · 1 hit paper · h-index 22

Molecular Biology top 5%
Organic Chemistry top 5%
Biomedical Engineering top 10%
Cellular and Molecular Neuroscience top 5%
Oncology top 10%

Co-authors: Robert H. Grubbs Keith V. Wood Thomas Machleidt Kris Zimmerman Marie K. Schwinn Mary P. Hall Paul Otto Lance P. Encell
Topics: bioluminescence and chemiluminescence research (19 papers)Biosensors and Analytical Detection (7 papers)Chemical Synthesis and Analysis (6 papers)
Cited by: Biophysics Molecular Biology Organic Chemistry
Journals: Journal of the American Chemical Society Journal of Biological Chemistry Nature Communications
Partner nations: United States Netherlands Switzerland

In The Last Decade

Thomas A. Kirkland

43 papers receiving 2.7k citations

Hit Papers

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What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

NanoLuc Complementation Reporter Optimized for Accurate Measurement of Protein Interactions in Cells

2015 904 citations Mary P. Hall, Paul Otto et al. profile →

Peers

Countries citing papers authored by Thomas A. Kirkland

Since Specialization

Citations

This map shows the geographic impact of Thomas A. Kirkland's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Thomas A. Kirkland with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Thomas A. Kirkland more than expected).

Fields of papers citing papers by Thomas A. Kirkland

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Thomas A. Kirkland. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Thomas A. Kirkland. The network helps show where Thomas A. Kirkland may publish in the future.

Co-authorship network of co-authors of Thomas A. Kirkland

This figure shows the co-authorship network connecting the top 25 collaborators of Thomas A. Kirkland. A scholar is included among the top collaborators of Thomas A. Kirkland based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Thomas A. Kirkland. Thomas A. Kirkland is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Pharmacodynamics of Akt drugs revealed by a kinase-modulated bioluminescent indicator 2025 ·Nature Chemical Biology ·(unknown),Chenzhou Hao,Chao Gao,Michiel Hageman,(unknown),Thomas A. Kirkland,Nathanael S. Gray,Yichi Su,Michael Z. Lin	1
2	In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes 2025 ·Chemistry - A European Journal ·(unknown),Alexander M. Sherwood,Thomas A. Kirkland,Thomas Krüger,(unknown),Olaf Kniemeyer,Markus Gressler,Dirk Hoffmeister	1
3	Optimized in vivo multispectral bioluminescent imaging of tumor biology using engineered BRET reporters 2024 ·iScience ·(unknown),Kshitij Parag‐Sharma,John J. Powers,Sonal Srivastava,Joel R. Walker,Thomas A. Kirkland,(unknown),Jennifer A. Prescher,Antonio L. Amelio	1
4	Kinase-Modulated Bioluminescent Indicators Enable Noninvasive Imaging of Drug Activity in the Brain 2023 ·ACS Central Science ·Yan Wu,Joel R. Walker,Michael Westberg,Ning Lin,Michelle Monje,Thomas A. Kirkland,Michael Z. Lin,Yichi Su	17
5	An optimized bioluminescent substrate for non-invasive imaging in the brain 2023 ·Nature Chemical Biology ·Yichi Su,Joel R. Walker,Mary P. Hall,Mark A. Klein,Xiang Wu,Lance P. Encell,Kerriann M. Casey,(unknown),Guosong Hong,Michael Z. Lin,Thomas A. Kirkland	38
6	In Vitro and In Vivo Analysis of Extracellular Vesicle‐Mediated Metastasis Using a Bright, Red‐Shifted Bioluminescent Reporter Protein 2022 ·SHILAP Revista de lepidopterología ·Gloria I. Perez,David Broadbent,(unknown),(unknown),Matthew P. Bernard,(unknown),(unknown),(unknown),(unknown),Jack R. Harkema,Joel R. Walker,Thomas A. Kirkland,Michael H. Bachmann,Jens C. Schmidt,Masamitsu Kanada	12
7	An Integrated Approach toward NanoBRET Tracers for Analysis of GPCR Ligand Engagement 2021 ·Molecules ·(unknown),Sergiy Levin,(unknown),(unknown),Robin Hurst,Mary P. Hall,Thomas Machleidt,Thomas A. Kirkland,Rachel Friedman Ohana	6
8	Novel NanoLuc substrates enable bright two-population bioluminescence imaging in animals 2020 ·Nature Methods ·Yichi Su,Joel R. Walker,Yun‐Hee Park,Thomas P. Smith,(unknown),Mary P. Hall,Louai Labanieh,Robin Hurst,David C. Wang,Lance P. Encell,Namdoo Kim,Feijie Zhang,Mark A. Kay,Kerriann M. Casey,Robbie G. Majzner,Jennifer R. Cochran,Crystal L. Mackall,Thomas A. Kirkland,Michael Z. Lin	128
9	NanoBiT System and Hydrofurimazine for Optimized Detection of Viral Infection in Mice—A Novel in Vivo Imaging Platform 2020 ·International Journal of Molecular Sciences ·(unknown),Giorgia Zambito,(unknown),Steve J. Cramer,Rob C. Hoeben,Clemens W.G.M. Löwik,Joel R. Walker,Thomas A. Kirkland,Thomas P. Smith,Wytske M. van Weerden,Jeroen de Vrij,Laura Mezzanotte	38
10	Evaluating Brightness and Spectral Properties of Click Beetle and Firefly Luciferases Using Luciferin Analogues: Identification of Preferred Pairings of Luciferase and Substrate for In Vivo Bioluminescence Imaging 2020 ·Molecular Imaging and Biology ·Giorgia Zambito,(unknown),Yanto Ridwan,Mary P. Hall,Ce Shi,Thomas A. Kirkland,Lance P. Encell,Clemens W.G.M. Löwik,Laura Mezzanotte	21
11	Red-shifted click beetle luciferase mutant expands the multicolor bioluminescent palette for deep tissue imaging 2020 ·iScience ·Giorgia Zambito,Mary P. Hall,Monika G. Wood,(unknown),Yanto Ridwan,Fabio Stellari,Ce Shi,Thomas A. Kirkland,Lance P. Encell,(unknown),Laura Mezzanotte	32
12	5,5-Dialkylluciferins are thermal stable substrates for bioluminescence-based detection systems 2020 ·PLoS ONE ·Ce Shi,(unknown),Mary P. Hall,Paul Otto,Monika G. Wood,(unknown),Lance P. Encell,Thomas Machleidt,Keith V. Wood,Thomas A. Kirkland	1
13	Utilizing a Simple Method for Stoichiometric Protein Labeling to Quantify Antibody Blockade 2019 ·Scientific Reports ·Rachel Friedman Ohana,Robin Hurst,(unknown),Sergiy Levin,Thomas Machleidt,Thomas A. Kirkland,Lance P. Encell,Matthew B. Robers,Keith V. Wood	9
14	Click beetle luciferase mutant and near infrared naphthyl-luciferins for improved bioluminescence imaging 2018 ·Nature Communications ·Mary P. Hall,Carolyn C. Woodroofe,Monika G. Wood,Ivo Que,(unknown),Yanto Ridwan,Ce Shi,Thomas A. Kirkland,Lance P. Encell,Keith V. Wood,Clemens W.G.M. Löwik,Laura Mezzanotte	110
15	Target engagement and drug residence time can be observed in living cells with BRET 2015 ·Nature Communications ·Matthew B. Robers,Melanie L. Dart,Carolyn C. Woodroofe,Chad Zimprich,Thomas A. Kirkland,Thomas Machleidt,Kevin R. Kupcho,Sergiy Levin,(unknown),(unknown),Andrew L. Niles,Rachel Friedman Ohana,Danette L. Daniels,Michael R. Slater,Monika G. Wood,Mei Cong,Yi‐Qiang Cheng,Keith V. Wood	196
16	Discovery of novel and potent aryl diamines as leukotriene A4 hydrolase inhibitors 2008 ·Bioorganic & Medicinal Chemistry Letters ·(unknown),John G. Bauman,(unknown),(unknown),(unknown),Thomas A. Kirkland,Monica J. Kochanny,Dao Lentz,Amy Liang,Lisa M. Mendoza,Gary B. Phillips,Jih‐Lie Tseng,(unknown),Hong Ye,(unknown),John F. Parkinson,William J. Guilford	11
17	Synthesis of glutamic acid analogs as potent inhibitors of leukotriene A4 hydrolase 2008 ·Bioorganic & Medicinal Chemistry ·Thomas A. Kirkland,Marc Adler,John G. Bauman,(unknown),Jesper Z. Haeggström,(unknown),Monica J. Kochanny,Amy Liang,Lisa M. Mendoza,Gary B. Phillips,Marjolein Thunnissen,Lan Trinh,Marc Whitlow,Bin Ye,Hong Ye,John F. Parkinson,William J. Guilford	29
18	Synthesis of N-alkyl glycine amides as potent inhibitors of leukotriene A4 hydrolase 2008 ·Bioorganic & Medicinal Chemistry Letters ·Bin Ye,John G. Bauman,(unknown),David D. Davey,(unknown),(unknown),Thomas A. Kirkland,Monica J. Kochanny,Amy Liang,Dao Lentz,Karen May,Lisa M. Mendoza,Gary B. Phillips,(unknown),Sabine Schlyer,Jih‐Lie Tseng,(unknown),Hong Ye,John F. Parkinson,William J. Guilford	11
19	Anti‐tumor efficacy of the nucleoside analog 1‐(2‐deoxy‐2‐fluoro‐4‐thio‐β‐D‐arabinofuranosyl) cytosine (4′‐thio‐FAC) in human pancreatic and ovarian tumor xenograft models 2005 ·International Journal of Cancer ·Deborah A. Zajchowski,Sandra L. Biroc,(unknown),(unknown),Jens Hoffmann,John W. Bauman,Thomas A. Kirkland,Babu Subramanyam,Jun Shen,Elena Ho,Jih‐Lie Tseng,Harald Dinter	7
20	Total Synthesis of (+)‐Ambruticin S. 2003 ·ChemInform ·(unknown),Robert J. Cherney,John Colucci,Christine Courillon,Leo S. Geraci,Thomas A. Kirkland,Matthew A. Marx,Matthias Schneider,Stephen F. Martin	1

About Thomas A. Kirkland

Thomas A. Kirkland is a scholar working on Molecular Biology, Biophysics and Organic Chemistry, having authored 43 papers that have together received 2.7k indexed citations. Recurring topics across this work include bioluminescence and chemiluminescence research (19 papers), Biosensors and Analytical Detection (7 papers) and Chemical Synthesis and Analysis (6 papers). The work is most often cited by research in Biophysics (200 citations), Molecular Biology (2.0k citations) and Organic Chemistry (637 citations). Thomas A. Kirkland has collaborated with scholars based in United States, Netherlands and Switzerland. Frequent co-authors include Robert H. Grubbs, Keith V. Wood, Thomas Machleidt, Kris Zimmerman, Marie K. Schwinn, Mary P. Hall, Paul Otto, Lance P. Encell, Monika G. Wood and Christopher T. Eggers. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Nature Communications.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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