Fred C. Christians

6.9k total citations · 1 hit paper
19 papers, 1.8k citations indexed

About

Fred C. Christians is a scholar working on Molecular Biology, Cancer Research and Pathology and Forensic Medicine. According to data from OpenAlex, Fred C. Christians has authored 19 papers receiving a total of 1.8k indexed citations (citations by other indexed papers that have themselves been cited), including 15 papers in Molecular Biology, 4 papers in Cancer Research and 3 papers in Pathology and Forensic Medicine. Recurrent topics in Fred C. Christians's work include DNA Repair Mechanisms (9 papers), CRISPR and Genetic Engineering (4 papers) and Epigenetics and DNA Methylation (4 papers). Fred C. Christians is often cited by papers focused on DNA Repair Mechanisms (9 papers), CRISPR and Genetic Engineering (4 papers) and Epigenetics and DNA Methylation (4 papers). Fred C. Christians collaborates with scholars based in United States, Switzerland and Italy. Fred C. Christians's co-authors include Jonathan D. Oliner, Philip C. Hanawalt, Lawrence A. Loeb, Heiko Müller, Kristian Helin, Elena Prosperini, Elena Vigo, Emanuela Grassilli, Adrian P. Bracken and Maria Cristina Moroni and has published in prestigious journals such as Cell, Proceedings of the National Academy of Sciences and Genes & Development.

In The Last Decade

Fred C. Christians

18 papers receiving 1.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis

2001 621 citations Heiko Müller, Adrian P. Bracken et al. Genes & Development profile →

Peers

Fred C. Christians

ONCOL

GENET

PFM

Shaun P. Scott Australia

Vimla Band United States

Nigel J. O’Neil Canada

Yusuke Nakamura Japan

Kouichi Tatsumi Japan

Deborah DeFeo United States

Takehisa Matsumoto Japan

Luciana E. Giono Argentina

Irina I. Dianova United Kingdom

KumKum Khanna Australia

Shaun P. Scott Australia

Fred C. Christians

1.8k ×1.1

950 ×1.7

ONCOL

297 ×0.9

GENET

517 ×1.9

106 ×1.2

PFM

Citations per year, relative to Fred C. Christians Fred C. Christians (= 1×) peers Shaun P. Scott

Countries citing papers authored by Fred C. Christians

Since Specialization

Citations

This map shows the geographic impact of Fred C. Christians's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Fred C. Christians with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Fred C. Christians more than expected).

Fields of papers citing papers by Fred C. Christians

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Fred C. Christians. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Fred C. Christians. The network helps show where Fred C. Christians may publish in the future.

Co-authorship network of co-authors of Fred C. Christians

This figure shows the co-authorship network connecting the top 25 collaborators of Fred C. Christians. A scholar is included among the top collaborators of Fred C. Christians based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Fred C. Christians. Fred C. Christians is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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19 of 19 papers shown

Babb, Paul, Damek V. Spacek, Kevin Brick, et al.. (2025). In-matrix library preparation for metagenomic sequencing of microbial cell-free DNA. Journal of Clinical Microbiology. 63(12). e0094425–e0094425.

Christians, Fred C., Kristin H. Jarman, Shivkumar Venkatasubrahmanyam, et al.. (2024). Analytical and clinical validation of direct detection of antimicrobial resistance markers by plasma microbial cell-free DNA sequencing. Journal of Clinical Microbiology. 62(10). e0042524–e0042524. 5 indexed citations

Mei, Rui, Earl Hubbell, Stefan Bekiranov, et al.. (2003). Probe selection for high-density oligonucleotide arrays. Proceedings of the National Academy of Sciences. 100(20). 11237–11242. 103 indexed citations

McGall, Glenn H. & Fred C. Christians. (2002). High-Density GeneChip Oligonucleotide Probe Arrays. Advances in biochemical engineering, biotechnology. 77. 21–42. 36 indexed citations

Müller, Heiko, Adrian P. Bracken, Maria Cristina Moroni, et al.. (2001). E2Fs regulate the expression of genes involved in differentiation, development, proliferation, and apoptosis. Genes & Development. 15(3). 267–285. 621 indexed citations breakdown →

Simpson, Laura J., Jing Li, Danny Liaw, et al.. (2001). PTEN Expression Causes Feedback Upregulation of Insulin Receptor Substrate 2. Molecular and Cellular Biology. 21(12). 3947–3958. 55 indexed citations

Davis, Brian M., Lance P. Encell, Steven P. Zielske, et al.. (2001). Applied molecular evolution of O ⁶ -benzylguanine-resistant DNA alkyltransferases in human hematopoietic cells. Proceedings of the National Academy of Sciences. 98(9). 4950–4954. 17 indexed citations

Harkin, D. Paul, James Bean, David B. Miklos, et al.. (1999). Induction of GADD45 and JNK/SAPK-Dependent Apoptosis following Inducible Expression of BRCA1. Cell. 97(5). 575–586. 480 indexed citations

Abril, Nieves, et al.. (1999). Human O6 -alkylguanine-DNA alkyltransferase: protection against alkylating agents and sensitization to dibromoalkanes. Carcinogenesis. 20(11). 2089–2094. 14 indexed citations

10.

Christians, Fred C., Léonardo Scapozza, Andreas Crameri, Gerd Folkers, & Willem P.C. Stemmer. (1999). Directed evolution of thymidine kinase for AZT phosphorylation using DNA family shuffling. Nature Biotechnology. 17(3). 259–264. 99 indexed citations

11.

Christians, Fred C., et al.. (1997). Creation of human alkyltransferases resistant to O6-benzylguanine.. PubMed. 57(10). 2007–12. 29 indexed citations

12.

Suzuki, Motoshi, Fred C. Christians, Baek Kim, et al.. (1996). Tolerance of different proteins for amino acid diversity. Molecular Diversity. 2(1-2). 111–118. 24 indexed citations

13.

Loeb, Lawrence A. & Fred C. Christians. (1996). Multiple mutations in human cancers. Mutation research. Fundamental and molecular mechanisms of mutagenesis. 350(1). 279–286. 60 indexed citations

14.

Christians, Fred C. & Lawrence A. Loeb. (1996). Novel human DNA alkyltransferases obtained by random substitution and genetic selection in bacteria.. Proceedings of the National Academy of Sciences. 93(12). 6124–6128. 34 indexed citations

15.

Christians, Fred C., et al.. (1995). Potential Sources of Multiple Mutations in Human Cancers. Preventive Medicine. 24(4). 329–332. 18 indexed citations

16.

Christians, Fred C., et al.. (1995). LACK OF MICROSATELLITE INSTABILITY IN HUMAN PROSTATE-CANCER. International Journal of Oncology. 6(6). 1173–6. 2 indexed citations

17.

Christians, Fred C. & Philip C. Hanawalt. (1994). Repair in ribosomal RNA genes is deficient in xeroderma pigmentosum group C and in Cockayne's syndrome cells. Mutation Research Letters. 323(4). 179–187. 35 indexed citations

18.

Christians, Fred C. & Philip C. Hanawalt. (1993). Lack of transcription-coupled repair in mammalian ribosomal RNA genes. Biochemistry. 32(39). 10512–10518. 72 indexed citations

19.

Christians, Fred C. & Philip C. Hanawalt. (1992). Inhibition of transcription and strand-specific DNA repair by α-amanitin in Chinese hamster ovary cells. Mutation Research/DNA Repair. 274(2). 93–101. 88 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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