Swen Hoelder

2.5k total citations · 1 hit paper
22 papers, 1.5k citations indexed

About

Swen Hoelder is a scholar working on Molecular Biology, Cell Biology and Organic Chemistry. According to data from OpenAlex, Swen Hoelder has authored 22 papers receiving a total of 1.5k indexed citations (citations by other indexed papers that have themselves been cited), including 19 papers in Molecular Biology, 6 papers in Cell Biology and 4 papers in Organic Chemistry. Recurrent topics in Swen Hoelder's work include Protein Degradation and Inhibitors (7 papers), Protein Structure and Dynamics (6 papers) and Microtubule and mitosis dynamics (6 papers). Swen Hoelder is often cited by papers focused on Protein Degradation and Inhibitors (7 papers), Protein Structure and Dynamics (6 papers) and Microtubule and mitosis dynamics (6 papers). Swen Hoelder collaborates with scholars based in United Kingdom, Germany and Canada. Swen Hoelder's co-authors include Paul Workman, Paul A. Clarke, Stefan Knapp, Nathan Brown, Lewis R. Vidler, Corine Mas-Droux, Richard Bayliss, Daniel K. Whelligan, Douglas W. Thomson and Dawn Taylor and has published in prestigious journals such as Angewandte Chemie International Edition, Molecular Cell and PLoS ONE.

In The Last Decade

Swen Hoelder

21 papers receiving 1.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Discovery of small molecule cancer drugs: Successes, challenges and opportunities

2012 438 citations Swen Hoelder, Paul A. Clarke et al. Molecular Oncology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Swen Hoelder United Kingdom	16	1.1k	390	246	242	226	22	1.5k
Paul Bamborough United Kingdom	29	1.8k 1.6×	468 1.2×	330 1.3×	337 1.4×	387 1.7×	58	2.5k
Christian Grütter Germany	25	1.4k 1.2×	483 1.2×	400 1.6×	301 1.2×	117 0.5×	30	2.0k
Mathew P. Martin United Kingdom	19	1.1k 1.0×	311 0.8×	499 2.0×	273 1.1×	166 0.7×	35	1.6k
Richard A. Norman United Kingdom	18	1.0k 0.9×	325 0.8×	269 1.1×	165 0.7×	66 0.3×	26	1.5k
Douglas R. Dougan United States	19	918 0.8×	378 1.0×	293 1.2×	152 0.6×	219 1.0×	32	1.6k
Roxana E. Iacob United States	24	1.6k 1.4×	267 0.7×	679 2.8×	100 0.4×	200 0.9×	34	2.4k
Bi‐Ching Sang United States	18	1.2k 1.1×	337 0.9×	711 2.9×	167 0.7×	232 1.0×	30	2.2k
Butrus Atrash United Kingdom	18	767 0.7×	260 0.7×	323 1.3×	114 0.5×	90 0.4×	39	1.2k
Joseph Schoepfer Switzerland	24	1.5k 1.4×	532 1.4×	470 1.9×	209 0.9×	90 0.4×	43	2.0k
John R. Regan United States	13	997 0.9×	512 1.3×	280 1.1×	314 1.3×	99 0.4×	19	1.5k

Countries citing papers authored by Swen Hoelder

Since Specialization

Citations

This map shows the geographic impact of Swen Hoelder's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Swen Hoelder with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Swen Hoelder more than expected).

Fields of papers citing papers by Swen Hoelder

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Swen Hoelder. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Swen Hoelder. The network helps show where Swen Hoelder may publish in the future.

Co-authorship network of co-authors of Swen Hoelder

This figure shows the co-authorship network connecting the top 25 collaborators of Swen Hoelder. A scholar is included among the top collaborators of Swen Hoelder based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Swen Hoelder. Swen Hoelder is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Liu, Manjuan, Amin Mirza, Craig McAndrew, et al.. (2023). Determination of Ligand-Binding Affinity (K_d) Using Transverse Relaxation Rate (R₂) in the Ligand-Observed ¹H NMR Experiment and Applications to Fragment-Based Drug Discovery. Journal of Medicinal Chemistry. 66(15). 10617–10627. 11 indexed citations

Vidler, Lewis R., P. J. Simpson, Bissan Al‐Lazikani, et al.. (2020). Solution structure of the Hop TPR2A domain and investigation of target druggability by NMR, biochemical and in silico approaches. Scientific Reports. 10(1). 16000–16000. 11 indexed citations

Heidenreich, David, Elizabeth R. Tucker, Monika Raab, et al.. (2019). Designing Dual Inhibitors of Anaplastic Lymphoma Kinase (ALK) and Bromodomain-4 (BRD4) by Tuning Kinase Selectivity. Journal of Medicinal Chemistry. 62(5). 2618–2637. 46 indexed citations

Vázquez, Santiago, Diana Carvalho, Eleanor Williams, et al.. (2018). Novel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure–Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of Concept. Journal of Medicinal Chemistry. 61(16). 7261–7272. 29 indexed citations

Gurden, Mark D., Isaac M. Westwood, Amir Faisal, et al.. (2015). Naturally Occurring Mutations in the MPS1 Gene Predispose Cells to Kinase Inhibitor Drug Resistance. Cancer Research. 75(16). 3340–3354. 24 indexed citations

Vidler, Lewis R., A. Chaikuad, Octovia Monteiro, et al.. (2015). Structure Enabled Design of BAZ2-ICR, A Chemical Probe Targeting the Bromodomains of BAZ2A and BAZ2B. Journal of Medicinal Chemistry. 58(5). 2553–2559. 71 indexed citations

Innocenti, Paolo, et al.. (2014). Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines. Organic & Biomolecular Chemistry. 13(3). 893–904. 15 indexed citations

Morley, Andrew, Angelo Pugliese, Kristian Birchall, et al.. (2013). Fragment-based hit identification: thinking in 3D. Drug Discovery Today. 18(23-24). 1221–1227. 129 indexed citations

Westwood, Isaac M., Kathy Boxall, Nathan Brown, et al.. (2013). Fragment-Based Screening Maps Inhibitor Interactions in the ATP-Binding Site of Checkpoint Kinase 2. PLoS ONE. 8(6). e65689–e65689. 12 indexed citations

10.

Vidler, Lewis R., P. Filippakopoulos, O. Fedorov, et al.. (2013). Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual Screening. Journal of Medicinal Chemistry. 56(20). 8073–8088. 101 indexed citations

11.

Hoelder, Swen, Paul A. Clarke, & Paul Workman. (2012). Discovery of small molecule cancer drugs: Successes, challenges and opportunities. Molecular Oncology. 6(2). 155–176. 438 indexed citations breakdown →

12.

Innocenti, Paolo, et al.. (2012). Synthesis of amino-substituted indoles using the Bartoli reaction. Organic & Biomolecular Chemistry. 10(22). 4441–4441. 11 indexed citations

13.

Innocenti, Paolo, Kwai-Ming J. Cheung, Corine Mas-Droux, et al.. (2012). Design of Potent and Selective Hybrid Inhibitors of the Mitotic Kinase Nek2: Structure–Activity Relationship, Structural Biology, and Cellular Activity. Journal of Medicinal Chemistry. 55(7). 3228–3241. 56 indexed citations

14.

Vidler, Lewis R., Nathan Brown, Stefan Knapp, & Swen Hoelder. (2012). Druggability Analysis and Structural Classification of Bromodomain Acetyl-lysine Binding Sites. Journal of Medicinal Chemistry. 55(17). 7346–7359. 203 indexed citations

15.

Innocenti, Paolo, Corine Mas-Droux, Kathy Boxall, et al.. (2011). Benzimidazole Inhibitors Induce a DFG-Out Conformation of Never in Mitosis Gene A-Related Kinase 2 (Nek2) without Binding to the Back Pocket and Reveal a Nonlinear Structure−Activity Relationship. Journal of Medicinal Chemistry. 54(6). 1626–1639. 43 indexed citations

16.

Whelligan, Daniel K., Dawn Taylor, Douglas W. Thomson, et al.. (2010). Aminopyrazine Inhibitors Binding to an Unusual Inactive Conformation of the Mitotic Kinase Nek2: SAR and Structural Characterization. Journal of Medicinal Chemistry. 53(21). 7682–7698. 56 indexed citations

17.

Richards, Mark W., Laura O’Regan, Corine Mas-Droux, et al.. (2009). An Autoinhibitory Tyrosine Motif in the Cell-Cycle-Regulated Nek7 Kinase Is Released through Binding of Nek9. Molecular Cell. 36(4). 560–570. 78 indexed citations

18.

Whelligan, Daniel K., Douglas W. Thomson, Dawn Taylor, & Swen Hoelder. (2009). Two-Step Synthesis of Aza- and Diazaindoles from Chloroamino-N-heterocycles Using Ethoxyvinylborolane. The Journal of Organic Chemistry. 75(1). 11–15. 55 indexed citations

19.

Vogtherr, Martin, Krishna Saxena, Swen Hoelder, et al.. (2005). NMR Characterization of Kinase p38 Dynamics in Free and Ligand‐Bound Forms. Angewandte Chemie International Edition. 45(6). 993–997. 131 indexed citations

20.

Vogtherr, Martin, Krishna Saxena, Swen Hoelder, et al.. (2005). Charakterisierung der Dynamik der Kinase p38 in freiem und ligandgebundenem Zustand durch NMR‐Spektroskopie. Angewandte Chemie. 118(6). 1008–1012. 17 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact