Kristen E. Pauken

15.7k total citations · 7 hit papers
39 papers, 8.0k citations indexed

About

Kristen E. Pauken is a scholar working on Immunology, Oncology and Genetics. According to data from OpenAlex, Kristen E. Pauken has authored 39 papers receiving a total of 8.0k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Immunology, 27 papers in Oncology and 6 papers in Genetics. Recurrent topics in Kristen E. Pauken's work include Immune Cell Function and Interaction (31 papers), Cancer Immunotherapy and Biomarkers (22 papers) and CAR-T cell therapy research (15 papers). Kristen E. Pauken is often cited by papers focused on Immune Cell Function and Interaction (31 papers), Cancer Immunotherapy and Biomarkers (22 papers) and CAR-T cell therapy research (15 papers). Kristen E. Pauken collaborates with scholars based in United States, Japan and United Kingdom. Kristen E. Pauken's co-authors include Arlene H. Sharpe, E. John Wherry, Brian T. Fife, Jason M. Schenkel, Pamela M. Odorizzi, Michael Paley, Vaiva Vezys, Lalit K. Beura, Kathryn Fraser and David Masopust and has published in prestigious journals such as Science, Cell and Proceedings of the National Academy of Sciences.

In The Last Decade

Kristen E. Pauken

38 papers receiving 8.0k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The diverse functions of the PD1 inhibitory pathway

2017 1.4k citations Arlene H. Sharpe, Kristen E. Pauken Nature reviews. Immunology profile →
Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

2016 900 citations Kristen E. Pauken, Morgan A. Sammons et al. Science profile →
Overcoming T cell exhaustion in infection and cancer

2015 832 citations Kristen E. Pauken, E. John Wherry Trends in Immunology profile →
Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade

2016 804 citations Joseph L. Benci, Bihui Xu et al. Cell profile →
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal

2009 599 citations Brian T. Fife, Kristen E. Pauken et al. Nature Immunology profile →
Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion

2016 588 citations Bertram Bengsch, Andrew L. Johnson et al. Immunity profile →
Resident memory CD8 T cells trigger protective innate and adaptive immune responses

2014 545 citations Jason M. Schenkel, Kathryn Fraser et al. Science profile →

Peers

Countries citing papers authored by Kristen E. Pauken

Since Specialization

Citations

This map shows the geographic impact of Kristen E. Pauken's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kristen E. Pauken with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kristen E. Pauken more than expected).

Fields of papers citing papers by Kristen E. Pauken

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kristen E. Pauken. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kristen E. Pauken. The network helps show where Kristen E. Pauken may publish in the future.

Co-authorship network of co-authors of Kristen E. Pauken

This figure shows the co-authorship network connecting the top 25 collaborators of Kristen E. Pauken. A scholar is included among the top collaborators of Kristen E. Pauken based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kristen E. Pauken. Kristen E. Pauken is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Single-Cell Analyses Reveal a Functionally Heterogeneous Exhausted CD8+ T-cell Subpopulation That Is Correlated with Response to Checkpoint Therapy in Melanoma 2025 ·Cancer Research ·Kelly M. Mahuron, (unknown), (unknown), (unknown), (unknown), Laura A. Huppert, (unknown), Margaret M. Lowe, (unknown), (unknown), Katy K. Tsai, Melissa Chow, Meromit Singer, Jason M. Schenkel, Arlene H. Sharpe, Michael D. Rosenblum, Kristen E. Pauken, Adil Daud	2
2	In vivo antibody labeling route and fluorophore dictate labeling efficiency, sensitivity, and longevity 2025 ·The Journal of Immunology ·(unknown), (unknown), (unknown), (unknown), (unknown), (unknown), Kristen E. Pauken, Jason M. Schenkel	0
3	Neoadjuvant immune checkpoint therapy: Enabling insights into fundamental human immunology and clinical benefit 2025 ·Cancer Cell ·Kristen E. Pauken, Omar Alhalabi, Sangeeta Goswami, Padmanee Sharma	3
4	Next-generation combination approaches for immune checkpoint therapy 2024 ·Nature Immunology ·Sangeeta Goswami, Kristen E. Pauken, Linghua Wang, Padmanee Sharma	32
5	Formate Supplementation Enhances Antitumor CD8+ T-cell Fitness and Efficacy of PD-1 Blockade 2023 ·Cancer Discovery ·Jared H. Rowe, Ilaria Elia, (unknown), Emily F. Gaudiano, (unknown), Sheila Johnson, (unknown), (unknown), Shakchhi Joshi, Martin W. LaFleur, Joon Seok Park, Kristen E. Pauken, Joshua D. Rabinowitz, Gordon J. Freeman, Marcia C. Haigis, Arlene H. Sharpe	26
6	Localization, tissue biology and T cell state — implications for cancer immunotherapy 2023 ·Nature reviews. Immunology ·Jason M. Schenkel, Kristen E. Pauken	61
7	Repertoire analyses reveal T cell antigen receptor sequence features that influence T cell fate 2022 ·Nature Immunology ·Kaitlyn A. Lagattuta, Joyce B. Kang, Aparna Nathan, Kristen E. Pauken, A. Helena Jonsson, Deepak A. Rao, Arlene H. Sharpe, Kazuyoshi Ishigaki, Soumya Raychaudhuri	41
8	TCR-sequencing in cancer and autoimmunity: barcodes and beyond 2022 ·Trends in Immunology ·Kristen E. Pauken, Kaitlyn A. Lagattuta, Benjamin Y. Lu, Liliana E. Lucca, Adil Daud, David A. Hafler, Harriet M. Kluger, Soumya Raychaudhuri, Arlene H. Sharpe	30
9	Emerging concepts in PD-1 checkpoint biology 2021 ·Seminars in Immunology ·Kristen E. Pauken, James A. Torchia, Apoorvi Chaudhri, Arlene H. Sharpe, Gordon J. Freeman	120
10	A bilateral tumor model identifies transcriptional programs associated with patient response to immune checkpoint blockade 2020 ·Proceedings of the National Academy of Sciences ·Ivy X. Chen, (unknown), Kristen E. Pauken, Vikram R. Juneja, Kamila Naxerova, Michelle Wu, Matthias Pinter, Debattama R. Sen, Meromit Singer, Arlene H. Sharpe, Rakesh K. Jain	32
11	The PD-1 Pathway Regulates Development and Function of Memory CD8+ T Cells following Respiratory Viral Infection 2020 ·Cell Reports ·Kristen E. Pauken, Jernej Godec, Pamela M. Odorizzi, Keturah Brown, Kathleen B. Yates, Shin Foong Ngiow, Kelly P. Burke, Seth Maleri, Shannon Grande, Loise M. Francisco, Mohammed-Alkhatim Ali, Sabrina Imam, Gordon J. Freeman, W. Nicholas Haining, E. John Wherry, Arlene H. Sharpe	78
12	Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade breakdown → 2016 ·Science ·Kristen E. Pauken, Morgan A. Sammons, Pamela M. Odorizzi, Sasikanth Manne, Jernej Godec, Omar Khan, Adam Drake, Zeyu Chen, Debattama R. Sen, Makoto Kurachi, R. Anthony Barnitz, Caroline Bartman, Bertram Bengsch, Alexander C. Huang, Jason M. Schenkel, Golnaz Vahedi, W. Nicholas Haining, Shelley L. Berger, E. John Wherry	900
13	CD4+ T cell anergy prevents autoimmunity and generates regulatory T cell precursors 2016 ·Nature Immunology ·Lokesh A. Kalekar, (unknown), Sarada L. Nandiwada, Wing Y. Lam, (unknown), Na Zhang, Gretta L. Stritesky, Deepali Malhotra, Kristen E. Pauken, Jonathan L. Linehan, Maeve O’Sullivan, Brian T. Fife, Kristin A. Hogquist, Marc K. Jenkins, Daniel L. Mueller	171
14	Bioenergetic Insufficiencies Due to Metabolic Alterations Regulated by the Inhibitory Receptor PD-1 Are an Early Driver of CD8 + T Cell Exhaustion breakdown → 2016 ·Immunity ·Bertram Bengsch, Andrew L. Johnson, Makoto Kurachi, Pamela M. Odorizzi, Kristen E. Pauken, John Attanasio, Erietta Stelekati, Laura M. McLane, Michael Paley, Greg M. Delgoffe, E. John Wherry	588
15	Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade breakdown → 2016 ·Cell ·Joseph L. Benci, Bihui Xu, Yu Qiu, Tony J. Wu, Hannah Dada, Christina Twyman-Saint Victor, Lisa Cucolo, David S.M. Lee, Kristen E. Pauken, Alexander C. Huang, Tara C. Gangadhar, Ravi K. Amaravadi, Lynn M. Schuchter, Michael D. Feldman, Hemant Ishwaran, Robert H. Vonderheide, Amit Maity, E. John Wherry, Andy J. Minn	804
16	Cutting Edge: Identification of Autoreactive CD4+ and CD8+ T Cell Subsets Resistant to PD-1 Pathway Blockade 2015 ·The Journal of Immunology ·Kristen E. Pauken, Christine E Nelson, Tijana Martinov, Justin A. Spanier, (unknown), (unknown), Clare F. Quarnstrom, Kevin C. Osum, Jason M. Schenkel, Marc K. Jenkins, Bruce R. Blazar, Vaiva Vezys, Brian T. Fife	37
17	SnapShot: T Cell Exhaustion 2015 ·Cell ·Kristen E. Pauken, E. John Wherry	81
18	Resident memory CD8 T cells trigger protective innate and adaptive immune responses breakdown → 2014 ·Science ·Jason M. Schenkel, Kathryn Fraser, Lalit K. Beura, Kristen E. Pauken, Vaiva Vezys, David Masopust	545
19	Cutting Edge: Type 1 Diabetes Occurs despite Robust Anergy among Endogenous Insulin-Specific CD4 T Cells in NOD Mice 2013 ·The Journal of Immunology ·Kristen E. Pauken, Jonathan L. Linehan, Justin A. Spanier, (unknown), Lokesh A. Kalekar, Bryce A. Binstadt, James Moon, Daniel L. Mueller, Marc K. Jenkins, Brian T. Fife	40
20	Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR–induced stop signal breakdown → 2009 ·Nature Immunology ·Brian T. Fife, Kristen E. Pauken, Todd N. Eagar, (unknown), Jenny Wu, Qizhi Tang, Miyuki Azuma, Matthew F. Krummel, Jeffrey A. Bluestone	599

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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