Sasikanth Manne

12.8k total citations · 4 hit papers
32 papers, 3.4k citations indexed

About

Sasikanth Manne is a scholar working on Immunology, Oncology and Molecular Biology. According to data from OpenAlex, Sasikanth Manne has authored 32 papers receiving a total of 3.4k indexed citations (citations by other indexed papers that have themselves been cited), including 24 papers in Immunology, 11 papers in Oncology and 7 papers in Molecular Biology. Recurrent topics in Sasikanth Manne's work include Immune Cell Function and Interaction (21 papers), T-cell and B-cell Immunology (11 papers) and Immunotherapy and Immune Responses (9 papers). Sasikanth Manne is often cited by papers focused on Immune Cell Function and Interaction (21 papers), T-cell and B-cell Immunology (11 papers) and Immunotherapy and Immune Responses (9 papers). Sasikanth Manne collaborates with scholars based in United States, Egypt and Japan. Sasikanth Manne's co-authors include E. John Wherry, Alexander C. Huang, Omar Khan, Makoto Kurachi, Zeyu Chen, Bertram Bengsch, Golnaz Vahedi, Josephine R. Giles, Shin Foong Ngiow and Shelley L. Berger and has published in prestigious journals such as Science, Cell and Nature Communications.

In The Last Decade

Sasikanth Manne

31 papers receiving 3.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade

2016 900 citations Kristen E. Pauken, Morgan A. Sammons et al. Science profile →
Developmental Relationships of Four Exhausted CD8+ T Cell Subsets Reveals Underlying Transcriptional and Epigenetic Landscape Control Mechanisms

2020 598 citations Jean‐Christophe Beltra, Sasikanth Manne et al. Immunity profile →
The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs

2019 243 citations Anthony Virtue, Sam J. McCright et al. Science Translational Medicine profile →
LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity

2024 110 citations Lawrence P. Andrews, Jian Cui et al. Cell profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Sasikanth Manne United States	22	2.2k	1.8k	952	257	215	32	3.4k
Youjin Lee United States	16	3.0k 1.4×	1.3k 0.7×	709 0.7×	189 0.7×	258 1.2×	17	3.9k
Álvaro Teijeira Spain	33	2.4k 1.1×	2.2k 1.2×	937 1.0×	294 1.1×	189 0.9×	74	3.9k
Michele Ardolino Canada	17	2.0k 0.9×	1.4k 0.8×	481 0.5×	193 0.8×	159 0.7×	31	2.7k
Nathalie Bendriss‐Vermare France	35	3.4k 1.6×	2.0k 1.1×	842 0.9×	274 1.1×	333 1.5×	63	4.5k
Mark P. Rubinstein United States	32	3.4k 1.6×	2.1k 1.2×	817 0.9×	339 1.3×	298 1.4×	76	4.6k
Jeong Kim United States	13	3.9k 1.8×	2.2k 1.2×	1.0k 1.1×	265 1.0×	188 0.9×	18	5.2k
Jianxun Song United States	32	2.1k 1.0×	1.1k 0.6×	1.2k 1.3×	358 1.4×	427 2.0×	94	3.8k
Carmela De Santo United Kingdom	25	2.6k 1.2×	1.3k 0.7×	752 0.8×	351 1.4×	164 0.8×	40	3.6k
Isao Tawara Japan	28	2.6k 1.2×	1.1k 0.6×	821 0.9×	263 1.0×	152 0.7×	105	4.0k
Gesine Bug Germany	35	1.2k 0.6×	1.3k 0.7×	1.6k 1.7×	184 0.7×	242 1.1×	141	4.2k

Countries citing papers authored by Sasikanth Manne

Since Specialization

Citations

This map shows the geographic impact of Sasikanth Manne's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Sasikanth Manne with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Sasikanth Manne more than expected).

Fields of papers citing papers by Sasikanth Manne

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Sasikanth Manne. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Sasikanth Manne. The network helps show where Sasikanth Manne may publish in the future.

Co-authorship network of co-authors of Sasikanth Manne

This figure shows the co-authorship network connecting the top 25 collaborators of Sasikanth Manne. A scholar is included among the top collaborators of Sasikanth Manne based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Sasikanth Manne. Sasikanth Manne is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Huang, Yinghui, Shin Foong Ngiow, Amy E. Baxter, et al.. (2025). Continuous expression of TOX safeguards exhausted CD8 T cell epigenetic fate. Science Immunology. 10(105). eado3032–eado3032. 11 indexed citations

Shukla, Deepa, Sasikanth Manne, Shuguang Jiang, et al.. (2025). Optimal pairing of binder and co-stimulatory domains improves dual CART cell efficacy. Molecular Therapy. 33(11). 5556–5571.

Andrews, Lawrence P., Jian Cui, Anthony R. Cillo, et al.. (2024). LAG-3 and PD-1 synergize on CD8+ T cells to drive T cell exhaustion and hinder autocrine IFN-γ-dependent anti-tumor immunity. Cell. 187(16). 4355–4372.e22. 110 indexed citations breakdown →

Wu, Jennifer E., Sasikanth Manne, Shin Foong Ngiow, et al.. (2023). In vitro modeling of CD8 ⁺ T cell exhaustion enables CRISPR screening to reveal a role for BHLHE40. Science Immunology. 8(86). eade3369–eade3369. 33 indexed citations

Baxter, Amy E., Hua Huang, Josephine R. Giles, et al.. (2023). The SWI/SNF chromatin remodeling complexes BAF and PBAF differentially regulate epigenetic transitions in exhausted CD8+ T cells. Immunity. 56(6). 1320–1340.e10. 42 indexed citations

Grebinoski, Stephanie, Qianxia Zhang, Anthony R. Cillo, et al.. (2022). Autoreactive CD8+ T cells are restrained by an exhaustion-like program that is maintained by LAG3. Nature Immunology. 23(6). 868–877. 70 indexed citations

McLane, Laura M., Shin Foong Ngiow, Zeyu Chen, et al.. (2021). Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells. Cell Reports. 35(6). 109120–109120. 77 indexed citations

Abdel-Hakeem, Mohamed S., Sasikanth Manne, Jean‐Christophe Beltra, et al.. (2021). Epigenetic scarring of exhausted T cells hinders memory differentiation upon eliminating chronic antigenic stimulation. Nature Immunology. 22(8). 1008–1019. 147 indexed citations

Ghouse, Shanawaz M., Surya Kumari Vadrevu, Sasikanth Manne, et al.. (2020). Therapeutic Targeting of Vasculature in the Premetastatic and Metastatic Niches Reduces Lung Metastasis. The Journal of Immunology. 204(4). 990–1000. 37 indexed citations

10.

Mansouri, H., Sasikanth Manne, Surya Kumari Vadrevu, et al.. (2019). The Codon 72 TP53 Polymorphism Contributes to TSC Tumorigenesis through the Notch–Nodal Axis. Molecular Cancer Research. 17(8). 1639–1651. 4 indexed citations

11.

Virtue, Anthony, Sam J. McCright, Jasmine M. Wright, et al.. (2019). The gut microbiota regulates white adipose tissue inflammation and obesity via a family of microRNAs. Science Translational Medicine. 11(496). 243 indexed citations breakdown →

12.

Zappasodi, Roberta, Sadna Budhu, Matthew D. Hellmann, et al.. (2018). Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity. Cancer Cell. 33(6). 1017–1032.e7. 113 indexed citations

13.

Bengsch, Bertram, Takuya Ohtani, Omar Khan, et al.. (2018). Epigenomic-Guided Mass Cytometry Profiling Reveals Disease-Specific Features of Exhausted CD8 T Cells. Immunity. 48(5). 1029–1045.e5. 183 indexed citations

14.

Stelekati, Erietta, Zeyu Chen, Sasikanth Manne, et al.. (2018). Long-Term Persistence of Exhausted CD8 T Cells in Chronic Infection Is Regulated by MicroRNA-155. Cell Reports. 23(7). 2142–2156. 71 indexed citations

15.

Tomov, Vesselin T., Chi Wai Lau, Ajinkya Pattekar, et al.. (2017). Differentiation and Protective Capacity of Virus-Specific CD8+ T Cells Suggest Murine Norovirus Persistence in an Immune-Privileged Enteric Niche. Immunity. 47(4). 723–738.e5. 51 indexed citations

16.

Manne, Sasikanth, Yan Zhou, Surya Kumari Vadrevu, et al.. (2017). Notch transactivates Rheb to maintain the multipotency of TSC-null cells. Nature Communications. 8(1). 1848–1848. 19 indexed citations

17.

Chen, Zeyu, Erietta Stelekati, Makoto Kurachi, et al.. (2017). miR-150 Regulates Memory CD8 T Cell Differentiation via c-Myb. Cell Reports. 20(11). 2584–2597. 54 indexed citations

18.

Pauken, Kristen E., Morgan A. Sammons, Pamela M. Odorizzi, et al.. (2016). Epigenetic stability of exhausted T cells limits durability of reinvigoration by PD-1 blockade. Science. 354(6316). 1160–1165. 900 indexed citations breakdown →

19.

Patel, Jayvadan K., JH Cho, Sasikanth Manne, et al.. (2015). Exosomes mediate the acquisition of the disease phenotypes by cells with normal genome in tuberous sclerosis complex. Oncogene. 35(23). 3027–3036. 37 indexed citations

20.

Vadrevu, Surya Kumari, Navin K. Chintala, Sharad Sharma, et al.. (2014). Complement C5a Receptor Facilitates Cancer Metastasis by Altering T-Cell Responses in the Metastatic Niche. Cancer Research. 74(13). 3454–3465. 161 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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