Klaus Heeg

14.6k citations

223 papers · 11.5k indexed · 3 hit papers · h-index 54

Impact in

Immunology top 0.1%
- Immune Response and Inflammation
- Immunotherapy and Immune Responses
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- interferon and immune responses
Microbiology top 0.2%
- Antimicrobial Peptides and Activities

Papers in

Immunology 142
- Immune Response and Inflammation 74
- Immune Cell Function and Interaction 67
- Immunotherapy and Immune Responses 64
- T-cell and B-cell Immunology 62
Molecular Medicine 19
- Antibiotic Resistance in Bacteria 19

Co-authors: Hermann Wagner Alexander H. Dalpke Grayson B. Lipford Stefan Zimmermann Thomas Miethke Tim Sparwasser Claudia Wahl Martin Röcken
Journals: European Journal of Immunology (25 papers)The Journal of Immunology (23 papers)Immunology (8 papers)Infection and Immunity (7 papers)Immunobiology (5 papers)
Partner nations: Germany United States France

In The Last Decade

Klaus Heeg

221 papers receiving 11.1k citations

Hit Papers

align trajectories log scale

Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells 1998 · 680 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1998 European Journal of Immunology
1998 The EMBO Journal
1992 The Journal of Experimental Medicine

Peers

Countries citing papers authored by Klaus Heeg

Since Specialization

Citations

This map shows the geographic impact of Klaus Heeg's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Klaus Heeg with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Klaus Heeg more than expected).

Fields of papers citing papers by Klaus Heeg

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Klaus Heeg. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Klaus Heeg. The network helps show where Klaus Heeg may publish in the future.

Co-authors

The 25 scholars most cited alongside Klaus Heeg, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Klaus Heeg Line = papers co-authored together Klaus Heeg links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	IL-1β knockout increases the intestinal abundancy of Akkermansia muciniphila Beneficial Microbes ·Maren Bechberger, Tatjana Eigenbrod, Sébastien Boutin, Klaus Heeg, Konrad A. Bode	2023	2
2	Integrative Analysis of Whole Genome Sequencing and Phenotypic Resistance Toward Prediction of Trimethoprim-Sulfamethoxazole Resistance in Staphylococcus aureus Frontiers in Microbiology ·Dennis Nurjadi, Elfi Zizmann, Quan Chanthalangsy, Klaus Heeg, Sébastien Boutin	2021	23
3	Toll-like receptor 9 (TLR-9) promotor polymorphisms and gene expression are associated with persistent Staphylococcus aureus nasal carriage Clinical Microbiology and Infection ·Dennis Nurjadi, Klaus Heeg, Alexander N.R. Weber, Philipp Zanger	2018	16
4	Inhibition of Histone Deacetylases Permits Lipopolysaccharide-Mediated Secretion of Bioactive IL-1β via a Caspase-1–Independent Mechanism The Journal of Immunology ·Dominik Stammler, Tatjana Eigenbrod, Sarah Menz, Julia-Stefanie Frick, Matthew J. Sweet, Melanie R. Shakespear, Jonathan Jantsch, Isabel Siegert, Sabine J. Wölfle, Julian D. Langer, Ina Oehme, Liliana Schaefer, André Fischer, J. Knievel, Klaus Heeg, Alexander H. Dalpke, Konrad A. Bode	2015	39
5	Pasteurella multocida Toxin Manipulates T Cell Differentiation Frontiers in Microbiology ·Dagmar Hildebrand, Klaus Heeg, Katharina F. Kubatzky	2015	16
6	Functional variation reflects intra-strain diversity of Staphylococcus aureus small colony variants in the host–pathogen interaction International Journal of Medical Microbiology ·Dina Hilmi, Marijo Parčina, Konrad A. Bode, Jenny Ostrop, Sabine Schuett, Klaus Heeg, Wilma Ziebuhr, Olaf Sommerburg, Isabelle Bekeredjian‐Ding	2013	12
7	PD‐L1 expression on tolerogenic APCs is controlled by STAT‐3 European Journal of Immunology ·Sabine J. Wölfle, Julia Strebovsky, Holger Bartz, Aline Sähr, Caroline Arnold, Claus Kaiser, Alexander H. Dalpke, Klaus Heeg	2010	268
8	Purified apoptotic bodies stimulate plasmacytoid dendritic cells to produce IFN-alpha Autoimmunity ·Petra Heyder, Isabelle Bekeredjian‐Ding, Marijo Parčina, Norbert Blank, Anthony D. Ho, Martin Herrmann, Hanns‐Martin Lorenz, Klaus Heeg, Martin R. Schiller	2007	24
9	Induction of Suppressor of Cytokine Signaling-1 by Toxoplasma gondii Contributes to Immune Evasion in Macrophages by Blocking IFN-γ Signaling The Journal of Immunology ·Stefan Zimmermann, Peter J. Murray, Klaus Heeg, Alexander H. Dalpke	2006	86
10	Differential effects of CpG‐DNA in Toll‐like receptor‐2/‐4/‐9 tolerance and cross‐tolerance Immunology ·Alexander H. Dalpke, Martin D. Lehner, Thomas Härtung, Klaus Heeg	2005	89
11	Deficiency in immunoglobulin G2 antibodies against staphylococcal enterotoxin C1 defines a subgroup of patients with atopic dermatitis Clinical & Experimental Allergy ·Salima Mrabet‐Dahbi, Kristine Breuer, Martina Klotz, Udo Herz, Klaus Heeg, Thomas Werfel, Harald Renz	2005	20
12	Quantitative detection of periodontopathogens by real-time PCR Journal of Microbiological Methods ·Claudia Nonnenmacher, Alexander H. Dalpke, Reinier Mutters, Klaus Heeg	2004	113
13	Immunostimulatory CpG-DNA Activates Murine Microglia The Journal of Immunology ·Alexander H. Dalpke, Martin Schäfer, Markus Frey, Stefan Zimmermann, Johannes Tebbe, Eberhard Weihe, Klaus Heeg	2002	134
14	DNA activates human immune cells through a CpG sequence‐dependent manner Immunology ·Michael G. Bauer, Klaus Heeg, Hermann Wagner, Grayson B. Lipford	1999	133
15	Bacterial DNA and immunostimulatory CpG oligonucleotides trigger maturation and activation of murine dendritic cells European Journal of Immunology ·Tim Sparwasser, Eva-Sophie Koch, R. Martin Vabulas, Klaus Heeg, Grayson B. Lipford, Joachim W. Ellwart, Hermann Wagner Hit paper breakdown →	1998	680
16	Macrophages sense pathogens via DNA motifs: induction of tumor necrosis factor‐α‐mediated shock European Journal of Immunology ·Tim Sparwasser, Thomas Miethke, Grayson B. Lipford, Andreas Erdmann, Hans Häcker, Klaus Heeg, Hermann Wagner	1997	363
17	Identification of H‐2K^b Binding and Immunogenic Peptides from Human Papilloma Virus Tumour Antigens E6 and E7 Scandinavian Journal of Immunology ·Stefan Bauer, Klaus Heeg, Hermann Wagner, Grayson B. Lipford	1995	26
18	Triggering of CD8+ cytotoxic T lymphocytes via CD3-epsilon differs from triggering via alpha/beta T cell receptor. CD3-epsilon-induced cytotoxicity occurs in the absence of protein kinase C and does not result in exocytosis of serine esterases The Journal of Immunology ·Hartmut Hengel, H Wagner, Klaus Heeg	1991	9
19	Nachweis von Chlamydia trachomatis in der klinischen Routine: höhere Sensitivität der Zellkultur gegenüber dem Mikroimmunfluoreszenztest Geburtshilfe und Frauenheilkunde ·K. Sterzik, B. Rosenbusch, B Danner, Klaus Heeg, A. V. Wolf, C. Lauritzen	1988	1
20	Allorestricted cytotoxic T cells. Large numbers of allo-H-2Kb-restricted antihapten and antiviral cytotoxic T cell populations clonally develop in vitro from murine splenic precursor T cells. The Journal of Experimental Medicine ·Jörg Reimann, Dieter Kabelitz, Klaus Heeg, Hermann Wagner	1985	10

About Klaus Heeg

Klaus Heeg is a scholar working on Immunology, Molecular Medicine, Clinical Biochemistry, Microbiology and Endocrinology, having authored 223 papers that have together received 11.5k indexed citations. Recurring topics across this work include Immune Response and Inflammation (74 papers), Immune Cell Function and Interaction (67 papers), Immunotherapy and Immune Responses (64 papers), T-cell and B-cell Immunology (62 papers), Antimicrobial Resistance in Staphylococcus (22 papers), Bacterial Identification and Susceptibility Testing (20 papers), Antibiotic Resistance in Bacteria (19 papers) and RNA Interference and Gene Delivery (15 papers). The work is most often cited by research in Immunology (7.5k citations), Microbiology (890 citations), Endocrinology (369 citations), Molecular Medicine (333 citations) and Infectious Diseases (1.1k citations). Klaus Heeg has collaborated with scholars based in Germany, United States and France. Frequent co-authors include Hermann Wagner, Alexander H. Dalpke, Grayson B. Lipford, Stefan Zimmermann, Thomas Miethke, Tim Sparwasser, Claudia Wahl, Martin Röcken, Oliver Egeter and Hans Häcker. Their work appears in journals such as European Journal of Immunology, The Journal of Immunology, Immunology, Infection and Immunity and Immunobiology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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