Karin Kolmodin

1.7k citations

20 papers · 1.1k indexed · h-index 15

Impact in

Computational Theory and Mathematics top 2%
- Computational Drug Discovery Methods
Pharmacology top 5%
- Cholinesterase and Neurodegenerative Diseases
- Pharmacogenetics and Drug Metabolism

Papers in

Computational Theory and Mathematics 8
- Computational Drug Discovery Methods 8
Pharmacology 4
- Cholinesterase and Neurodegenerative Diseases 4

Co-authors: Johan Åqvist John Marelius Isabella Feierberg Jan Florián Arieh Warshel Anders Hallberg Sherry F. Queener Johanna Fälting
Journals: FEBS Letters (3 papers)Journal of Medicinal Chemistry (3 papers)Proteins Structure Function and Bioinformatics (2 papers)Journal of the American Chemical Society (1 paper)ACS Medicinal Chemistry Letters (1 paper)
Partner nations: Sweden United States United Kingdom

In The Last Decade

Karin Kolmodin

20 papers receiving 1.1k citations

Peers

Countries citing papers authored by Karin Kolmodin

Since Specialization

Citations

This map shows the geographic impact of Karin Kolmodin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Karin Kolmodin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Karin Kolmodin more than expected).

Fields of papers citing papers by Karin Kolmodin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Karin Kolmodin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Karin Kolmodin. The network helps show where Karin Kolmodin may publish in the future.

Co-authors

The 25 scholars most cited alongside Karin Kolmodin, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Karin Kolmodin Line = papers co-authored together Karin Kolmodin links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Toward β-Secretase-1 Inhibitors with Improved Isoform Selectivity Journal of Medicinal Chemistry ·Patrik Johansson, 隼人庄山, Ian Gurrell, Galo Méndez-Matías, Susanna Eketjäll, Clay W. Scott, Gvido Cebers, 四郎小川, Michael J. McKenzie, Haydn G. Beaton, Paul R. J. Davey, Karin Kolmodin, Jörg Holenz, Mark E. Duggan, Samantha Budd Haeberlein, Roland W. Bürli	2018	25
2	Creation of Novel Cores for β-Secretase (BACE-1) Inhibitors: A Multiparameter Lead Generation Strategy ACS Medicinal Chemistry Letters ·Jenny Viklund, Karin Kolmodin, Gunnar Nordvall, Britt‐Marie Swahn, Mats Svensson, Ylva Gravenfors, Fredrik Rahm	2014	9
3	AZ-4217: A High Potency BACE Inhibitor Displaying Acute Central Efficacy in Different In Vivo Models and Reduced Amyloid Deposition in Tg2576 Mice Journal of Neuroscience ·Susanna Eketjäll, Juliette Janson, Fredrik Jeppsson, Kanchhi Maharjan, Karin Kolmodin, Ju-FangWang, A. vanSonderen, Kristilyn Eliason, Song Xiagan, Tin Nguyen Trung, Eric Moorhead, A. Berg, Sofia Karlström, Britt‐Marie Swahn, Johanna Fälting	2013	34
4	Aminoimidazoles as BACE-1 inhibitors: The challenge to achieve in vivo brain efficacy Bioorganic & Medicinal Chemistry Letters ·Britt‐Marie Swahn, Jörg Holenz, Bella Jane, Karin Kolmodin, Imtiaz Ahmad Warich, Niklas Plobeck, Didier Rotticci, Vinit Yadav, Brittany M. Benjamin, Stefan von Berg, Johanna Fälting, Biljana Georgievska, Susanne Gustavsson, Jan Neelissen, Margareta Ek, Lise‐Lotte Olsson	2012	34
5	Discovery of AZD3839, a Potent and Selective BACE1 Inhibitor Clinical Candidate for the Treatment of Alzheimer Disease Journal of Biological Chemistry ·Fredrik Jeppsson, Susanna Eketjäll, Juliette Janson, Sofia Karlström, Susanne Gustavsson, Lise‐Lotte Olsson, N. Gleawketgarn, Bart A. Ploeger, Gvido Cebers, Karin Kolmodin, Britt‐Marie Swahn, Stefan von Berg, Tjerk Bueters, Johanna Fälting	2012	107
6	New Aminoimidazoles as β-Secretase (BACE-1) Inhibitors Showing Amyloid-β (Aβ) Lowering in Brain Journal of Medicinal Chemistry ·Ylva Gravenfors, Jenny Viklund, Tatiana Lizbeth Pérez Lozada, U. Govardhani, Sofia Karlström, Bella Jane, Karin Kolmodin, Imtiaz Ahmad Warich, Stefan von Berg, Fredrik von Kieseritzky, 郑霞云, Britt‐Marie Swahn, Lise‐Lotte Olsson, Patrik Johansson, Susanna Eketjäll, Johanna Fälting, Fredrik Jeppsson, Kia Strömberg, Juliette Janson, Fredrik Rahm	2012	56
7	Evidence for dimeric BACE-mediated APP processing Biochemical and Biophysical Research Communications ·Shaobo Jin, Karin Agerman, Karin Kolmodin, Hong Yong Kim, Camilla Dahlqvist, Anders Juréus, Gang Liu, Johanna Fälting, Stefan von Berg, Johan Lundkvist, Urban Lendahl	2010	21
8	Design of compound libraries for fragment screening Journal of Computer-Aided Molecular Design ·Niklas Blomberg, David A. Cosgrove, Peter W. Kenny, Karin Kolmodin	2009	58
9	State-of-the-art Tools for Computational Site of Metabolism Predictions: Comparative Analysis, Mechanistical Insights, and Future Applications Drug Metabolism Reviews ·Lovisa Afzelius, Catrin Hasselgren Arnby, Anders Broo, Lars Carlsson, Céspedes, Ulrik Jurva, B. K. Charlotte Kjellander, Karin Kolmodin, Kristina Nilsson, Florian Raubacher, Lars Weidolf	2007	88
10	Design, synthesis, and computational affinity prediction of ester soft drugs as inhibitors of dihydrofolate reductase from Pneumocystis carinii European Journal of Pharmaceutical Sciences ·C. I. Mateş, Karin Kolmodin, Johan Åqvist, Sherry F. Queener, Anders Hallberg	2004	16
11	Computational Study of the Influence of Solvent on ¹⁶O/¹⁸O Equilibrium Isotope Effects in Phosphate Deprotonation Reactions Journal of the American Chemical Society ·Karin Kolmodin, Victor B. Luzhkov, Johan Åqvist	2002	14
12	The catalytic mechanism of protein tyrosine phosphatases revisited FEBS Letters ·Karin Kolmodin, Johan Åqvist	2001	85
13	Design, Synthesis, Computational Prediction, and Biological Evaluation of Ester Soft Drugs as Inhibitors of Dihydrofolate Reductase fromPneumocystis carinii Journal of Medicinal Chemistry ·C. I. Mateş, Karin Kolmodin, Johan Åqvist, Sherry F. Queener, Anders Hallberg	2001	74
14	Computational modeling of the rate limiting step in low molecular weight protein tyrosine phosphatase FEBS Letters ·Karin Kolmodin, Johan Åqvist	1999	23
15	Mechanistic alternatives in phosphate monoester hydrolysis: What conclusions can be drawn from available experimental data? Chemistry & Biology ·Johan Åqvist, Karin Kolmodin, Jan Florián, Arieh Warshel	1999	131
16	Computational modeling of catalysis and binding in low-molecular-weight protein tyrosine phosphatase International Journal of Quantum Chemistry ·Karin Kolmodin, Johan �Qvist	1999	14
17	Prediction of a ligand‐induced conformational change in the catalytic core of Cdc25A FEBS Letters ·Karin Kolmodin, Johan Åqvist	1999	9
18	Mechanism of substrate dephosphorylation in lowMr protein tyrosine phosphatase Proteins Structure Function and Bioinformatics ·Karin Kolmodin, مهری استادی, Johan �Qvist	1999	22
19	Mechanism of substrate dephosphorylation in low Mr protein tyrosine phosphatase Proteins Structure Function and Bioinformatics ·Karin Kolmodin, P. Nordlund, Johan Åqvist	1999	1
20	Q: a molecular dynamics program for free energy calculations and empirical valence bond simulations in biomolecular systems Journal of Molecular Graphics and Modelling ·John Marelius, Karin Kolmodin, Isabella Feierberg, Johan Åqvist	1998	289

About Karin Kolmodin

Karin Kolmodin is a scholar working on Computational Theory and Mathematics, Pharmacology, Physiology, Molecular Biology and Immunology, having authored 20 papers that have together received 1.1k indexed citations. Recurring topics across this work include Computational Drug Discovery Methods (8 papers), ATP Synthase and ATPases Research (6 papers), Protein Tyrosine Phosphatases (6 papers), Alzheimer's disease research and treatments (5 papers), Cholinesterase and Neurodegenerative Diseases (4 papers), Tuberculosis Research and Epidemiology (2 papers), DNA and Nucleic Acid Chemistry (2 papers) and Protein Structure and Dynamics (2 papers). The work is most often cited by research in Computational Theory and Mathematics (303 citations), Pharmacology (88 citations), Molecular Biology (684 citations), Organic Chemistry (235 citations) and Pharmacology (135 citations). Karin Kolmodin has collaborated with scholars based in Sweden, United States and United Kingdom. Frequent co-authors include Johan Åqvist, John Marelius, Isabella Feierberg, Johan Åqvist, Jan Florián, Arieh Warshel, Anders Hallberg, Sherry F. Queener, Johanna Fälting and Britt‐Marie Swahn. Their work appears in journals such as FEBS Letters, Journal of Medicinal Chemistry, Proteins Structure Function and Bioinformatics, Journal of the American Chemical Society and ACS Medicinal Chemistry Letters.

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