Johan Åqvist

16.4k citations

204 papers · 13.4k indexed · 4 hit papers · h-index 57

Impact in

Molecular Biology top 0.5%
- Protein Structure and Dynamics
- RNA and protein synthesis mechanisms
- DNA and Nucleic Acid Chemistry
- RNA modifications and cancer
- Ion channel regulation and function
Computational Theory and Mathematics top 0.1%
- Computational Drug Discovery Methods

Papers in

Molecular Biology 167
- Protein Structure and Dynamics 75
- RNA and protein synthesis mechanisms 41
- RNA modifications and cancer 25
- Receptor Mechanisms and Signaling 22
- Chemical Synthesis and Analysis 14
Physiology 9

Co-authors: Arieh Warshel Victor B. Luzhkov Bjørn Olav Brandsdal John Marelius Jens Carlsson Stefan Trobro Hugo Gutiérrez‐de‐Terán Sinisa Bjelic
Journals: Biochemistry (30 papers)Journal of Chemical Theory and Computation (10 papers)Proceedings of the National Academy of Sciences (9 papers)FEBS Letters (9 papers)Journal of Medicinal Chemistry (8 papers)
Partner nations: Sweden United States Norway

In The Last Decade

Johan Åqvist

199 papers receiving 13.1k citations

Hit Papers

align trajectories log scale

A new method for predicting binding affinity in computer-aided drug design 1994 · 986 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

1994 Protein Engineering Design and Selection
1993 Chemical Reviews
1991 PubMed
1990 The Journal of Physical Chemistry

Peers

Countries citing papers authored by Johan Åqvist

Since Specialization

Citations

This map shows the geographic impact of Johan Åqvist's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Johan Åqvist with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Johan Åqvist more than expected).

Fields of papers citing papers by Johan Åqvist

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Johan Åqvist. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Johan Åqvist. The network helps show where Johan Åqvist may publish in the future.

Co-authors

The 25 scholars most cited alongside Johan Åqvist, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Johan Åqvist Line = papers co-authored together Johan Åqvist links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Efficient Empirical Valence Bond Simulations with GROMACS Journal of Chemical Theory and Computation ·Gabriel Oanca, Florian van der Ent, Johan Åqvist	2023	18
2	Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family eLife ·Xiaohu Guo, Annika Söderholm, Sandesh Kanchugal P, Geir Villy Isaksen, Omar Warsi, Ulrich Eckhard, Silvia Trigüis, Adolf Gogoll, Jon Jerlström-Hultqvist, Johan Åqvist, Dan I. Andersson, M. Selmer	2021	20
3	Structural Basis of Inhibition of Human Insulin-Regulated Aminopeptidase (IRAP) by Benzopyran-Based Inhibitors Frontiers in Molecular Biosciences ·Sudarsana Reddy Vanga, Johan Åqvist, Anders Hallberg, Hugo Gutiérrez‐de‐Terán	2021	4
4	Evolution of Angiotensin Peptides and Peptidomimetics as Angiotensin II Receptor Type 2 (AT2) Receptor Agonists Biomolecules ·Silvana Vasile, Anders Hallberg, Jessica Sallander, Mathias Hallberg, Johan Åqvist, Hugo Gutiérrez‐de‐Terán	2020	17
5	Macrocyclic peptidomimetics as inhibitors of insulin-regulated aminopeptidase (IRAP) RSC Medicinal Chemistry ·Νicholas Barlow, Sudarsana Reddy Vanga, Jonas Sävmarker, Anja Sandström, Peta Burns, Anders Hallberg, Johan Åqvist, Hugo Gutiérrez‐de‐Terán, Mathias Hallberg, Mats Larhed, Siew Yeen Chai, Philip E. Thompson	2020	14
6	A Series of Analogues to the AT₂R Prototype Antagonist C38 Allow Fine Tuning of the Previously Reported Antagonist Binding Mode ChemistryOpen ·Rebecka Isaksson, Jens Lindman, Johan Wannberg, Jessica Sallander, Maria Backlund, Dhãniel Baraldi, Robert E. Widdop, Mathias Hallberg, Johan Åqvist, Hugo Gutiérrez‐de‐Terán, Johan Gising, Mats Larhed	2019	9
7	Inhibition of translation termination by small molecules targeting ribosomal release factors Scientific Reports ·Xueliang Ge, Ana Oliveira, Karin Hjort, Terese Bergfors, Hugo Gutiérrez‐de‐Terán, Dan I. Andersson, Suparna Sanyal, Johan Åqvist	2019	6
8	QligFEP: an automated workflow for small molecule free energy calculations in Q Journal of Cheminformatics ·Willem Jespers, Mauricio Esguerra, Johan Åqvist, Hugo Gutiérrez‐de‐Terán	2019	58
9	Complementary charge-based interaction between the ribosomal-stalk protein L7/12 and IF2 is the key to rapid subunit association Proceedings of the National Academy of Sciences ·Xueliang Ge, Chandra Sekhar Mandava, Christoffer Lind, Johan Åqvist, Suparna Sanyal	2018	24
10	A close-up view of codon selection in eukaryotic initiation RNA Biology ·Christoffer Lind, Mauricio Esguerra, Johan Åqvist	2017	6
11	The GPR139 reference agonists 1a and 7c, and tryptophan and phenylalanine share a common binding site Scientific Reports ·Anne Cathrine Nøhr, Willem Jespers, Mohamed A. Shehata, Leonard Floryan, Vignir Ísberg, Kirsten B. Andersen, Johan Åqvist, Hugo Gutiérrez‐de‐Terán, Hans Bräuner‐Osborne, David E. Gloriam	2017	23
12	Enzyme catalysis by entropy without Circe effect Proceedings of the National Academy of Sciences ·Masoud Kazemi, Fahmi Himo, Johan Åqvist	2016	50
13	Enzyme surface rigidity tunes the temperature dependence of catalytic rates Proceedings of the National Academy of Sciences ·Geir Villy Isaksen, Johan Åqvist, Bjørn Olav Brandsdal	2016	78
14	Permeation Redux: Thermodynamics and Kinetics of Ion Movement through Potassium Channels Biophysical Journal ·Richard Horn, Benoı̂t Roux, Johan Åqvist	2014	25
15	Computer Simulation of Primary Kinetic Isotope Effects in the Proposed Rate-limiting Step of the Glyoxalase I Catalyzed Reaction Journal of Biological Chemistry ·Isabella Feierberg, Victor B. Luzhkov, Johan Åqvist	2000	42
16	Computational modeling of the rate limiting step in low molecular weight protein tyrosine phosphatase FEBS Letters ·Karin Kolmodin, Johan Åqvist	1999	23
17	Metalloenzymes Involving Amino Acid-Residue and Related Radicals The Quarterly Review of Biology ·Johan Åqvist	1995	20
18	A molecular model for the retinol binding protein-transthyretin complex Journal of Molecular Graphics ·Johan Åqvist, Orlando Tapia	1992	16
19	Calculations of free energy profiles for the staphylococcal nuclease catalyzed reaction Biochemistry ·Johan Åqvist, Arieh Warshel	1989	69
20	Molecular dynamics as a tool for structural and functional predictions: the retinol binding protein and chloroplast C-terminal fragment of the L12 ribosomal protein cases. PubMed ·O. Tapia, Johan Åqvist	1989	3

About Johan Åqvist

Johan Åqvist is a scholar working on Molecular Biology, Physiology, Computational Theory and Mathematics, Physical and Theoretical Chemistry and Spectroscopy, having authored 204 papers that have together received 13.4k indexed citations. Recurring topics across this work include Protein Structure and Dynamics (75 papers), RNA and protein synthesis mechanisms (41 papers), Enzyme Structure and Function (39 papers), RNA modifications and cancer (25 papers), Computational Drug Discovery Methods (24 papers), Receptor Mechanisms and Signaling (22 papers), Spectroscopy and Quantum Chemical Studies (16 papers) and Chemical Synthesis and Analysis (14 papers). The work is most often cited by research in Molecular Biology (9.5k citations), Computational Theory and Mathematics (1.8k citations), Physical and Theoretical Chemistry (966 citations), Filtration and Separation (209 citations) and Atomic and Molecular Physics, and Optics (2.2k citations). Johan Åqvist has collaborated with scholars based in Sweden, United States and Norway. Frequent co-authors include Arieh Warshel, Victor B. Luzhkov, Bjørn Olav Brandsdal, John Marelius, Jens Carlsson, Stefan Trobro, Hugo Gutiérrez‐de‐Terán, Sinisa Bjelic, Tomas Hansson and Isabella Feierberg. Their work appears in journals such as Biochemistry, Journal of Chemical Theory and Computation, Proceedings of the National Academy of Sciences, FEBS Letters and Journal of Medicinal Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact