Kam‐Leung Siu

3.3k total citations · 1 hit paper
25 papers, 2.2k citations indexed

About

Kam‐Leung Siu is a scholar working on Molecular Biology, Immunology and Infectious Diseases. According to data from OpenAlex, Kam‐Leung Siu has authored 25 papers receiving a total of 2.2k indexed citations (citations by other indexed papers that have themselves been cited), including 14 papers in Molecular Biology, 14 papers in Immunology and 11 papers in Infectious Diseases. Recurrent topics in Kam‐Leung Siu's work include interferon and immune responses (12 papers), SARS-CoV-2 and COVID-19 Research (8 papers) and Redox biology and oxidative stress (4 papers). Kam‐Leung Siu is often cited by papers focused on interferon and immune responses (12 papers), SARS-CoV-2 and COVID-19 Research (8 papers) and Redox biology and oxidative stress (4 papers). Kam‐Leung Siu collaborates with scholars based in Hong Kong, China and France. Kam‐Leung Siu's co-authors include Dong‐Yan Jin, Kin‐Hang Kok, Kwok‐Yung Yuen, Chi‐Ping Chan, Man Lung Yeung, Sin‐Yee Fung, Kit‐San Yuen, Chi‐Ming Wong, Ching-Ping Chan and Dora Lai‐Wan Kwong and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Experimental Medicine.

In The Last Decade

Kam‐Leung Siu

23 papers receiving 2.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Severe acute respiratory syndrome Coronavirus ORF3a protein activates the NLRP3 inflammasome by promoting TRAF3‐dependent ubiquitination of ASC

2019 374 citations Kam‐Leung Siu, Kit‐San Yuen et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Kam‐Leung Siu Hong Kong	18	956	932	736	283	277	25	2.2k
Yi Zheng China	26	1.1k 1.1×	632 0.7×	925 1.3×	155 0.5×	394 1.4×	90	2.2k
Deli Huang United States	19	1.8k 1.9×	876 0.9×	854 1.2×	276 1.0×	409 1.5×	28	2.9k
Jin Wei China	20	527 0.6×	596 0.6×	573 0.8×	78 0.3×	190 0.7×	39	1.5k
Krystal Matthews United States	13	512 0.5×	635 0.7×	869 1.2×	183 0.6×	176 0.6×	14	1.8k
Chong-Shan Shi United States	19	1.2k 1.2×	381 0.4×	660 0.9×	233 0.8×	705 2.5×	23	2.2k
Yong Lin China	28	1.1k 1.2×	350 0.4×	484 0.7×	313 1.1×	1.2k 4.5×	92	2.7k
Mustafa Ulaşlı Türkiye	16	613 0.6×	628 0.7×	159 0.2×	88 0.3×	299 1.1×	35	1.6k
Sara Alonso Spain	23	320 0.3×	736 0.8×	577 0.8×	200 0.7×	159 0.6×	103	1.9k
Yea‐Lih Lin France	23	1.4k 1.4×	302 0.3×	538 0.7×	195 0.7×	197 0.7×	44	2.2k
Yasuo Ariumi Japan	25	1000 1.0×	341 0.4×	483 0.7×	236 0.8×	419 1.5×	59	1.9k

Countries citing papers authored by Kam‐Leung Siu

Since Specialization

Citations

This map shows the geographic impact of Kam‐Leung Siu's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kam‐Leung Siu with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kam‐Leung Siu more than expected).

Fields of papers citing papers by Kam‐Leung Siu

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kam‐Leung Siu. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kam‐Leung Siu. The network helps show where Kam‐Leung Siu may publish in the future.

Co-authorship network of co-authors of Kam‐Leung Siu

This figure shows the co-authorship network connecting the top 25 collaborators of Kam‐Leung Siu. A scholar is included among the top collaborators of Kam‐Leung Siu based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kam‐Leung Siu. Kam‐Leung Siu is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Tey, Sze Keong, et al.. (2025). Integrin β4‐Enriched Small Extracellular Vesicle as Drug Delivery Vehicle for Targeting Pulmonary Metastasis of Hepatocellular Carcinoma. Advanced Healthcare Materials. 14(28). e2502649–e2502649.

Fung, Sin‐Yee, Tao Ding, Yuan Zhou, et al.. (2025). Centrosome protein TAX1BP2 mediates STING-dependent immune response and potentiates anti-PD-1 efficacy in hepatocellular carcinoma. Molecular Therapy. 33(6). 2913–2930.

Sun, Xiaoyu, Chenhui Zhang, Sin‐Yee Fung, et al.. (2023). Superoxide dismutase A (SodA) is a c-di-GMP effector protein governing oxidative stress tolerance in Stenotrophomonas maltophilia. Microbiological Research. 278. 127535–127535. 7 indexed citations

Fung, Sin‐Yee, Kam‐Leung Siu, Huayue Lin, et al.. (2022). SARS-CoV-2 NSP13 helicase suppresses interferon signaling by perturbing JAK1 phosphorylation of STAT1. Cell & Bioscience. 12(1). 36–36. 38 indexed citations

Wong, Lok-Yin Roy, Zi‐Wei Ye, Pak‐Yin Lui, et al.. (2020). Middle East Respiratory Syndrome Coronavirus ORF8b Accessory Protein Suppresses Type I IFN Expression by Impeding HSP70-Dependent Activation of IRF3 Kinase IKKε. The Journal of Immunology. 205(6). 1564–1579. 29 indexed citations

Wang, Pei‐Hui, Zi‐Wei Ye, Kam‐Leung Siu, et al.. (2018). Inhibition of AIM 2 inflammasome activation by a novel transcript isoform of IFI 16. EMBO Reports. 19(10). 70 indexed citations

Lui, Pak‐Yin, Lok-Yin Roy Wong, Kam‐Leung Siu, et al.. (2016). Middle East respiratory syndrome coronavirus M protein suppresses type I interferon expression through the inhibition of TBK1-dependent phosphorylation of IRF3. Emerging Microbes & Infections. 5(1). 1–9. 104 indexed citations

Hu, Ligang, et al.. (2015). Loss of APD1 in Yeast Confers Hydroxyurea Sensitivity Suppressed by Yap1p Transcription Factor. Scientific Reports. 5(1). 7897–7897. 10 indexed citations

Siu, Kam‐Leung, Suying Bao, Pak C. Sham, et al.. (2015). PTPN21 exerts pro-neuronal survival and neuritic elongation via ErbB4/NRG3 signaling. The International Journal of Biochemistry & Cell Biology. 61. 53–62. 16 indexed citations

10.

Siu, Kam‐Leung, Chi‐Ping Chan, Kin‐Hang Kok, Patrick C. Y. Woo, & Dong‐Yan Jin. (2014). Suppression of innate antiviral response by severe acute respiratory syndrome coronavirus M protein is mediated through the first transmembrane domain. Cellular and Molecular Immunology. 11(2). 141–149. 83 indexed citations

11.

Siu, Kam‐Leung, Ching-Ping Chan, Kin‐Hang Kok, Patrick C. Y. Woo, & Dong‐Yan Jin. (2014). Comparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU1. Cell & Bioscience. 4(1). 3–3. 36 indexed citations

12.

Lei, Ting, Kam‐Leung Siu, Kin‐Hang Kok, et al.. (2012). Anti-ganglioside antibodies were not detected in human subjects infected with or vaccinated against 2009 pandemic influenza A (H1N1) virus. Vaccine. 30(16). 2605–2610. 11 indexed citations

13.

Kok, Kin‐Hang, et al.. (2011). The Double-Stranded RNA-Binding Protein PACT Functions as a Cellular Activator of RIG-I to Facilitate Innate Antiviral Response. Cell Host & Microbe. 9(4). 299–309. 149 indexed citations

14.

Siu, Kam‐Leung, Kin‐Hang Kok, Vincent Kwok‐Man Poon, et al.. (2009). Severe Acute Respiratory Syndrome Coronavirus M Protein Inhibits Type I Interferon Production by Impeding the Formation of TRAF3·TANK·TBK1/IKKϵ Complex. Journal of Biological Chemistry. 284(24). 16202–16209. 230 indexed citations

15.

Siu, Kam‐Leung, et al.. (2009). Severe acute respiratory syndrome coronavirus nucleocapsid protein does not modulate transcription of the human FGL2 gene. Journal of General Virology. 90(9). 2107–2113. 10 indexed citations

16.

Siu, Kam‐Leung, et al.. (2009). Loss of Yeast Peroxiredoxin Tsa1p Induces Genome Instability through Activation of the DNA Damage Checkpoint and Elevation of dNTP Levels. PLoS Genetics. 5(10). e1000697–e1000697. 37 indexed citations

17.

Siu, Kam‐Leung, Kin‐Hang Kok, Raymond Wai Ming Lung, et al.. (2008). An Epstein-Barr virus–encoded microRNA targets PUMA to promote host cell survival. The Journal of Experimental Medicine. 205(11). 2551–2560. 369 indexed citations

18.

Chan, Ching-Ping, Kam‐Leung Siu, King‐Tung Chin, et al.. (2006). Modulation of the Unfolded Protein Response by the Severe Acute Respiratory Syndrome Coronavirus Spike Protein. Journal of Virology. 80(18). 9279–9287. 185 indexed citations

19.

Zheng, B, et al.. (2004). Selective functional deficit in dendritic cell – T cell interaction is a crucial mechanism in chronic hepatitis B virus infection. Journal of Viral Hepatitis. 11(3). 217–224. 64 indexed citations

20.

Wong, Chi‐Ming, Kam‐Leung Siu, & Dong‐Yan Jin. (2004). Peroxiredoxin-null Yeast Cells Are Hypersensitive to Oxidative Stress and Are Genomically Unstable. Journal of Biological Chemistry. 279(22). 23207–23213. 106 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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