Jukka Hakkola

6.6k total citations · 1 hit paper
93 papers, 5.2k citations indexed

About

Jukka Hakkola is a scholar working on Pharmacology, Molecular Biology and Oncology. According to data from OpenAlex, Jukka Hakkola has authored 93 papers receiving a total of 5.2k indexed citations (citations by other indexed papers that have themselves been cited), including 48 papers in Pharmacology, 37 papers in Molecular Biology and 27 papers in Oncology. Recurrent topics in Jukka Hakkola's work include Pharmacogenetics and Drug Metabolism (48 papers), Drug Transport and Resistance Mechanisms (23 papers) and Hormonal Regulation and Hypertension (18 papers). Jukka Hakkola is often cited by papers focused on Pharmacogenetics and Drug Metabolism (48 papers), Drug Transport and Resistance Mechanisms (23 papers) and Hormonal Regulation and Hypertension (18 papers). Jukka Hakkola collaborates with scholars based in Finland, Sweden and United States. Jukka Hakkola's co-authors include Olavi Pelkonen, Hannu Raunio, Janne Hukkanen, Miia Turpeinen, Marcin Buler, Markku Pasanen, Paavo Honkakoski, Sisko Anttila, Jaana Rysä and Alan R. Boobis and has published in prestigious journals such as Journal of Biological Chemistry, SHILAP Revista de lepidopterología and PLoS ONE.

In The Last Decade

Jukka Hakkola

93 papers receiving 5.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Inhibition and induction of CYP enzymes in humans: an update

2020 253 citations Jukka Hakkola, Janne Hukkanen et al. Archives of Toxicology profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jukka Hakkola Finland	44	2.1k	1.6k	1.1k	699	597	93	5.2k
Michael W.H. Coughtrie United Kingdom	42	2.1k 1.0×	2.6k 1.6×	871 0.8×	783 1.1×	634 1.1×	139	6.2k
Markku Pasanen Finland	37	1.9k 0.9×	1.3k 0.8×	932 0.8×	739 1.1×	416 0.7×	138	4.8k
Jorge Goldstein United States	34	2.2k 1.1×	1.0k 0.6×	1.1k 1.0×	468 0.7×	528 0.9×	88	4.6k
Norie Murayama Japan	39	3.1k 1.5×	1.2k 0.8×	1.6k 1.5×	448 0.6×	386 0.6×	235	5.0k
Kouichi Yoshinari Japan	32	1.7k 0.8×	1.3k 0.8×	1.0k 0.9×	462 0.7×	245 0.4×	153	3.6k
Ronald N. Hines United States	45	2.5k 1.2×	1.6k 1.0×	1.2k 1.1×	1.4k 2.0×	866 1.5×	128	6.4k
Jean‐Marc Pascussi France	40	2.8k 1.3×	1.6k 1.0×	1.8k 1.6×	531 0.8×	469 0.8×	92	5.9k
Curtis J. Omiecinski United States	47	2.8k 1.4×	2.5k 1.5×	1.2k 1.1×	488 0.7×	836 1.4×	117	7.5k
Burhan I. Ghanayem United States	37	2.2k 1.1×	1.1k 0.7×	1.2k 1.1×	390 0.6×	914 1.5×	94	5.6k
Petr Pávek Czechia	41	1.2k 0.6×	1.5k 0.9×	1.6k 1.5×	898 1.3×	255 0.4×	159	5.2k

Countries citing papers authored by Jukka Hakkola

Since Specialization

Citations

This map shows the geographic impact of Jukka Hakkola's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jukka Hakkola with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jukka Hakkola more than expected).

Fields of papers citing papers by Jukka Hakkola

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jukka Hakkola. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jukka Hakkola. The network helps show where Jukka Hakkola may publish in the future.

Co-authorship network of co-authors of Jukka Hakkola

This figure shows the co-authorship network connecting the top 25 collaborators of Jukka Hakkola. A scholar is included among the top collaborators of Jukka Hakkola based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jukka Hakkola. Jukka Hakkola is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Szabó, Zoltán, J. Peters, Outi Kummu, et al.. (2024). Inhibition of activin receptor 2 signalling ameliorates metabolic dysfunction–associated steatotic liver disease in western diet/L-NAME induced cardiometabolic disease. Biomedicine & Pharmacotherapy. 175. 116683–116683. 2 indexed citations

Kummu, Outi, et al.. (2024). The fungicide propiconazole induces hepatic steatosis and activates PXR in a mouse model of diet-induced obesity. Archives of Toxicology. 99(3). 1203–1221. 3 indexed citations

Kummu, Outi, Vesa Koivukangas, Heidi Hautajärvi, et al.. (2022). Pregnane X receptor‒4β‐hydroxycholesterol axis in the regulation of overweight‐ and obesity‐induced hypertension. University of Oulu Repository (University of Oulu). 7 indexed citations

Hukkanen, Janne, et al.. (2022). Nuclear Receptor PXR in Drug-Induced Hypercholesterolemia. Cells. 11(3). 313–313. 25 indexed citations

Kummu, Outi, Terhi Piltonen, Laure Morin‐Papunen, et al.. (2020). Obesity Represses CYP2R1 , the Vitamin D 25‐Hydroxylase, in the Liver and Extrahepatic Tissues. JBMR Plus. 4(11). e10397–e10397. 51 indexed citations

Salonurmi, Tuire, Justiina Ronkainen, Tuulia Hyötyläinen, et al.. (2020). 4β-Hydroxycholesterol Signals From the Liver to Regulate Peripheral Cholesterol Transporters. Frontiers in Pharmacology. 11. 361–361. 16 indexed citations

Hakkola, Jukka, et al.. (2017). Extranuclear Sirtuins and Metabolic Stress. Antioxidants and Redox Signaling. 28(8). 662–676. 52 indexed citations

Dimova, Elitsa Y., Sohvi Hörkkö, Helena Gylling, et al.. (2016). Hypoxia-Inducible Factor Prolyl 4-Hydroxylase-2 Inhibition Protects Against Development of Atherosclerosis. Arteriosclerosis Thrombosis and Vascular Biology. 36(4). 608–617. 75 indexed citations

Hu, Hao, et al.. (2015). Tumour suppressor protein p53 regulates the stress activated bilirubin oxidase cytochrome P450 2A6. Toxicology and Applied Pharmacology. 289(1). 30–39. 8 indexed citations

10.

Hukkanen, Janne, Jukka Hakkola, & Jaana Rysä. (2013). Pregnane X receptor (PXR) – a contributor to the diabetes epidemic?. Drug metabolism and drug interactions. 29(1). 3–15. 37 indexed citations

11.

Anttila, Sisko, Hannu Raunio, & Jukka Hakkola. (2010). Cytochrome P450–Mediated Pulmonary Metabolism of Carcinogens. American Journal of Respiratory Cell and Molecular Biology. 44(5). 583–590. 62 indexed citations

12.

Korjamo, Timo, Ari Tolonen, Miia Turpeinen, et al.. (2009). Effects of Selective Serotonin Reuptake Inhibitors on Timolol Metabolism in Human Liver Microsomes and Cryo‐Preserved Hepatocytes. Basic & Clinical Pharmacology & Toxicology. 106(4). 302–309. 16 indexed citations

13.

Heikkinen, Terho, Jukka Hakkola, Kati Hakala, et al.. (2005). Functional role of P-glycoprotein in the human blood-placental barrier. Clinical Pharmacology & Therapeutics. 78(2). 123–131. 99 indexed citations

14.

Hukkanen, Janne, Olavi Pelkonen, Jukka Hakkola, & Hannu Raunio. (2002). Expression and Regulation of Xenobiotic-Metabolizing Cytochrome P450 (CYP) Enzymes in Human Lung. Critical Reviews in Toxicology. 32(5). 391–411. 245 indexed citations

15.

Pelkonen, Olavi, et al.. (2002). In Vitro Screening of Cytochrome P450 Induction Potential. PubMed. 105–137. 4 indexed citations

16.

Hakkola, Jukka, Hannu Raunio, Raija Purkunen, et al.. (2001). Cytochrome P450 3A Expression in the Human Fetal Liver: Evidence that CYP3A5 Is Expressed in Only a Limited Number of Fetal Livers. Neonatology. 80(3). 193–201. 56 indexed citations

17.

Hakkola, Jukka, Olavi Pelkonen, Markku Pasanen, & Hannu Raunio. (1998). Xenobiotic-Metabolizing Cytochrome P450 Enzymes in the Human Feto-Placental Unit: Role in Intrauterine Toxicity. Critical Reviews in Toxicology. 28(1). 35–72. 179 indexed citations

18.

Anttila, Sisko, Janne Hukkanen, Jukka Hakkola, et al.. (1997). Expression and Localization of CYP3A4 and CYP3A5 in Human Lung. American Journal of Respiratory Cell and Molecular Biology. 16(3). 242–249. 134 indexed citations

19.

Hakkola, Jukka. (1997). Expression of CYP1B1 in human adult and fetal tissues and differential inducibility of CYP1B1 and CYP1A1 by Ah receptor ligands in human placenta and cultured cells. Carcinogenesis. 18(2). 391–397. 172 indexed citations

20.

Hakkola, Jukka, et al.. (1992). 7‐Alkoxyquinoline O‐dealkylation by microsomes from human liver and placenta.. British Journal of Clinical Pharmacology. 34(5). 415–420. 7 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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