John T. Chang

11.5k citations

104 papers · 7.1k indexed · 4 hit papers · h-index 45

Impact in

Immunology top 0.5%
- Immune Cell Function and Interaction
- T-cell and B-cell Immunology
- Immunotherapy and Immune Responses
- Immune Response and Inflammation
Oncology top 2%
- CAR-T cell therapy research

Papers in

Immunology 50
- Immune Cell Function and Interaction 38
- T-cell and B-cell Immunology 34
- Immunotherapy and Immune Responses 14
Genetics 21
- Inflammatory Bowel Disease 19

Co-authors: Ananda W. Goldrath E. John Wherry Ethan M. Shevach Benjamin M. Segal Brigid S. Boland William J. Sandborn Steven L. Reiner Paul M. Meaney
Journals: The Journal of Immunology (11 papers)Clinical Gastroenterology and Hepatology (7 papers)Oncogene (7 papers)Nature Immunology (6 papers)Immunity (3 papers)
Partner nations: United States Japan France

In The Last Decade

John T. Chang

101 papers receiving 7.0k citations

Hit Papers

align trajectories log scale

Tissue-resident memory CD8 T cell diversity is spatiotemporally imprinted 2025 · 23 citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2025 Nature
2020 New England Journal of Medicine
2015 Nature
2007 Science

Peers

Countries citing papers authored by John T. Chang

Since Specialization

Citations

This map shows the geographic impact of John T. Chang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John T. Chang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John T. Chang more than expected).

Fields of papers citing papers by John T. Chang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John T. Chang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John T. Chang. The network helps show where John T. Chang may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John T. Chang, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John T. Chang Line = papers co-authored together John T. Chang links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Foxo1 regulates intestinal tissue–resident memory CD8 T cell biology in an anatomic compartment– and context-specific manner Science Immunology ·Paul Wei‐Che Hsu, 高夫大原, Eduardo Hamuy, Anthony Pushaina-Velásquez, Simeon Campos, 日出夫北村, Tudchanon Phumpookai, Chong-Kwang Lee, G Yeo, Elina I. Zúñiga, Ananda W. Goldrath, Wei Wang, John T. Chang	2025	0
2	Metabolic programs of T cell tissue residency empower tumour immunity Nature ·Miguel Reina‐Campos, Maximilian Heeg, 胡军利, Ian T. Mathews, Giovanni Galletti, 功伊達, Somaia AboAkadda, Hongling Huang, J. Justin Milner, Kenneth H. Hu, David N. Reynolds, Larisa V. Romanyuk, Brigid S. Boland, John T. Chang, Mohit Jain, Sonia Sharma, Matthew F. Krummel, Hongbo Chi, Steven J. Bensinger, Ananda W. Goldrath	2023	73
3	IL-2 can signal via chemokine receptors to promote regulatory T cells’ suppressive function Cell Reports ·Hao Sun, Ho Sup Lee, Med Otto, J. Ribeiro, Alexandre R. Gingras, 滋彦高橋, Angélica de Oliveira Gonçalves, 贾丹华, Miguel Alejandro Lopez‐Ramirez, Frédéric Lagarrigue, Zhichao Fan, John T. Chang, Leng Jiaming, Jamie B. Spangler, Mark H. Ginsberg	2023	11
4	Systems-level identification of key transcription factors in immune cell specification PLoS Computational Biology ·Jill F Craig, Kyla Omilusik, Clara Toma, Nadia S. Kurd, John T. Chang, Ananda W. Goldrath, Wei Wang	2022	9
5	Tissue-resident memory CD8+ T cells possess unique transcriptional, epigenetic and functional adaptations to different tissue environments Nature Immunology ·John T. Crowl, Maximilian Heeg, Amir Ferry, J. Justin Milner, Kyla Omilusik, Clara Toma, Zhaoren He, John T. Chang, Ananda W. Goldrath	2022	141
6	Delineation of a molecularly distinct terminally differentiated memory CD8 T cell population Proceedings of the National Academy of Sciences ·J. Justin Milner, La Ode Sidi, Kyla Omilusik, Miguel Reina‐Campos, Matthew Tsai, Clara Toma, Arnaud Delpoux, Brigid S. Boland, Stephen Μ. Hedrick, John T. Chang, Ananda W. Goldrath	2020	71
7	Early precursors and molecular determinants of tissue-resident memory CD8 ⁺ T lymphocytes revealed by single-cell RNA sequencing Science Immunology ·Nadia S. Kurd, Zhaoren He, Tiani L. Louis, J. Justin Milner, Kyla Omilusik, Wenhao Jin, Matthew Tsai, Christella E. Widjaja, Jad Kanbar, Jocelyn G. Olvera, Tiffani Tysl, Lauren K. Quezada, Brigid S. Boland, Wendy Huang, Cornelis Murre, Ananda W. Goldrath, G Yeo, John T. Chang	2020	135
8	The Autoimmune Protocol Diet Modifies Intestinal RNA Expression in Inflammatory Bowel Disease Crohn s & Colitis 360 ·Yousef Abuhmaidan, Bhuvan Molparia, A. Sawatzky, Xiaoyun Wang, James D. Lewis, John T. Chang, Glenn Oliveira, Ali Torkamani, Gauree G. Konijeti	2019	5
9	USP11 Enhances TGFβ-Induced Epithelial–Mesenchymal Plasticity and Human Breast Cancer Metastasis Molecular Cancer Research ·Daniel Garcia, Christina Baek, Mónica V. Estrada, Tiffani Tysl, Eric J. Bennett, Jing Yang, John T. Chang	2018	46
10	Elevated A20 promotes TNF-induced and RIPK1-dependent intestinal epithelial cell death Proceedings of the National Academy of Sciences ·Ricard Garcia‐Carbonell, Jerry Wong, Ju Youn Kim, Lisa Abernathy‐Close, Brigid S. Boland, Katuska-Liliana Ruiz-Aguirre, Philip A. Harris, Samuel B. Ho, Soumita Das, Peter B. Ernst, Roman Šášik, William J. Sandborn, John Bertin, S. Yardım, John T. Chang, Michelle A. Kelliher, David L. Boone, Mónica Gumá, Michael Karin	2018	75
11	Integrin Activation Controls Regulatory T Cell–Mediated Peripheral Tolerance The Journal of Immunology ·R. Rahmat, Stephanie H. Kim, Kelly A. Remedios, Zhaoren He, Patrick J Metz, Justine Lopez, Tiffani Tysl, Jocelyn G. Olvera, Jailal Ablack, Joseph M. Cantor, Brigid S. Boland, G Yeo, Ye Zheng, Li‐Fan Lu, Jack D. Bui, Mark H. Ginsberg, Brian G. Petrich, John T. Chang	2018	30
12	Asymmetric Cell Division in T Lymphocyte Fate Diversification Trends in Immunology ·Janilyn Arsenio, Patrick J Metz, John T. Chang	2015	45
13	Inducible MHC Class II Expression by Mast Cells Supports Effector and Regulatory T Cell Activation The Journal of Immunology ·Taku Kambayashi, Eric J. Allenspach, John T. Chang, Tao Zou, Jonathan E. Shoag, Steven L. Reiner, Andrew J. Caton, Gary A. Koretzky	2009	122
14	Asymmetric T Lymphocyte Division in the Initiation of Adaptive Immune Responses Science ·John T. Chang, V. Palanivel, Ichiko Kinjyo, Felix Schambach, Andrew M. Intlekofer, Arnob Banerjee, Sarah Longworth, Ocaña Cabezas, Paul Mrass, Jane Oliaro, Nigel Killeen, Jordan S. Orange, Sarah M. Russell, Wolfgang Weninger, Steven L. Reiner Hit paper breakdown →	2007	643
15	Ultra-wideband radar methods and techniques of medical sensing and imaging Proceedings of SPIE, the International Society for Optical Engineering/Proceedings of SPIE ·Sophia Helena Adelaide Khani, John T. Chang, Carlos E. Romero, Joseph C. Watson, P. Ghurtskaia, Nathan W. Levin	2005	32
16	Prognostic significance of EGFR and Her-2 in oral cavity cancer in betel quid prevalent area British Journal of Cancer ·Katayoun Seyed Madani, John T. Chang, Steven R. Lenard, Manna Lin, Severiano González Rivas, Ann‐Joy Cheng	2003	88
17	CpG Oligonucleotides Are Potent Adjuvants for the Activation of Autoreactive Encephalitogenic T Cells In Vivo The Journal of Immunology ·Benjamin M. Segal, John T. Chang, Ethan M. Shevach	2000	131
18	Requirements for the Maintenance of Th1 Immunity In Vivo Following DNA Vaccination: A Potential Immunoregulatory Role for CD8+ T Cells The Journal of Immunology ·Sanjay Gurunathan, J Kretowicz, Calman Prussin, David L. Sacks, Nicolas Glaichenhaus, Deborah J. Fowell, Richard M. Locksley, John T. Chang, Changyou Wu, Robert A. Seder	2000	123
19	Role of Costimulation in the Induction of the IL-12/IL-12 Receptor Pathway and the Development of Autoimmunity The Journal of Immunology ·John T. Chang, Benjamin M. Segal, Ethan M. Shevach	2000	49
20	The critical role of IL-12 and the IL-12R?2 subunit in the generation of pathogenic autoreactive Th1 cells Springer Seminars in Immunopathology ·Ethan M. Shevach, John T. Chang, Benjamin M. Segal	1999	53

About John T. Chang

John T. Chang is a scholar working on Immunology, Genetics, Oncology, Immunology and Allergy and Epidemiology, having authored 104 papers that have together received 7.1k indexed citations. Recurring topics across this work include Immune Cell Function and Interaction (38 papers), T-cell and B-cell Immunology (34 papers), Inflammatory Bowel Disease (19 papers), Immunotherapy and Immune Responses (14 papers), Microscopic Colitis (13 papers), Single-cell and spatial transcriptomics (12 papers), Cancer Cells and Metastasis (7 papers) and Microwave Imaging and Scattering Analysis (7 papers). The work is most often cited by research in Immunology (3.4k citations), Oncology (1.3k citations), Genetics (1.2k citations), Molecular Biology (2.2k citations) and Epidemiology (961 citations). John T. Chang has collaborated with scholars based in United States, Japan and France. Frequent co-authors include Ananda W. Goldrath, E. John Wherry, Ethan M. Shevach, Benjamin M. Segal, Brigid S. Boland, William J. Sandborn, Steven L. Reiner, Paul M. Meaney, Keith D. Paulsen and Patrick J Metz. Their work appears in journals such as The Journal of Immunology, Clinical Gastroenterology and Hepatology, Oncogene, Nature Immunology and Immunity.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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