John S. Rudge

14.2k citations

57 papers · 10.9k indexed · 3 hit papers · h-index 38

Impact in

Developmental Neuroscience top 0.5%
- Neurogenesis and neuroplasticity mechanisms
Ophthalmology top 0.2%
- Retinal Diseases and Treatments

Papers in

Developmental Neuroscience 9
- Neurogenesis and neuroplasticity mechanisms 9
Cellular and Molecular Neuroscience 15
- Nerve injury and regeneration 10

Co-authors: George D. Yancopoulos Stanley J. Wiegand Jocelyn Holash Samuel Davis Nicholas W. Gale Ella Ioffe Susan D. Croll Donna Hylton
Journals: European Journal of Neuroscience (5 papers)Proceedings of the National Academy of Sciences (5 papers)Experimental Neurology (5 papers)Developmental Brain Research (4 papers)Journal of Clinical Investigation (3 papers)
Partner nations: United States United Kingdom Germany

In The Last Decade

John S. Rudge

57 papers receiving 10.7k citations

Hit Papers

align trajectories log scale

VEGF-Trap: A VEGF blocker with potent antitumor effects 2002 · 1.3k citations

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if any of the following hold:

it has ≥500 total citations;
it reaches ≥1.5× the top-1% citation threshold for papers in the same subfield and year (the threshold is the minimum needed to enter the top 1%, not the average within it);
it reaches the top citation threshold in at least one of its specific research topics.

2002 Proceedings of the National Academy of Sciences
2000 Nature Medicine
2000 Nature

Peers

Countries citing papers authored by John S. Rudge

Since Specialization

Citations

This map shows the geographic impact of John S. Rudge's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John S. Rudge with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John S. Rudge more than expected).

Fields of papers citing papers by John S. Rudge

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John S. Rudge. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John S. Rudge. The network helps show where John S. Rudge may publish in the future.

Co-authorship network

The 25 scholars most cited alongside John S. Rudge, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John S. Rudge Line = papers co-authored together John S. Rudge links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Angiopoietins bind thrombomodulin and inhibit its function as a thrombin cofactor Scientific Reports ·Christopher Daly, Xiaozhong Qian, Carla Castanaro, Elizabeth Pasnikowski, 純冨岡, Benjamin R. Thomson, Susan E. Quaggin, Nicholas Papadopoulos, Ningning Li, John S. Rudge, Gavin Thurston, George D. Yancopoulos, Samuel Davis	2018	36
2	Resistance to Anti-VEGF Therapy Mediated by Autocrine IL6/STAT3 Signaling and Overcome by IL6 Blockade Cancer Research ·Alexandra Eichten, Lucay Han Ching, Alexander P. Adler, Li Zhang, Ella Ioffe, Asma Parveen, George D. Yancopoulos, John S. Rudge, Israel Lowy, Hsin Chieh Lin, Douglas MacDonald, Christopher Daly, Xunbao Duan, Gavin Thurston	2016	47
3	ERBB3/HER2 Signaling Promotes Resistance to EGFR Blockade in Head and Neck and Colorectal Cancer Models Molecular Cancer Therapeutics ·Li Zhang, Carla Castanaro, Н П Барсуков, Kevin Meyer, S. V. Zavjalets, Jeanette Fairhurst, Ashique Rafique, Terra Potocky, Jing Shan, Frank J. Delfino, Ergang Shi, Tammy Huang, Joel Martin, Gang Chen, Douglas MacDonald, John S. Rudge, Gavin Thurston, Christopher Daly	2014	42
4	Sustained VEGF Blockade Results in Microenvironmental Sequestration of VEGF by Tumors and Persistent VEGF Receptor-2 Activation Molecular Cancer Research ·Angela V. Kadenhe‐Chiweshe, Magnus L. Andersson, Kimberly W. McCrudden, Jason S. Frischer, 寺越佐知子, Jianzhong Huang, Jason C. Fisher, Jay H. Lefkowitch, Nikki Feirt, John S. Rudge, Jocelyn Holash, George D. Yancopoulos, Jessica J. Kandel, Darrell J. Yamashiro	2008	64
5	Inhibitors of growth factor receptors, signaling pathways and angiogenesis as therapeutic molecular agents Cancer and Metastasis Reviews ·Jocelyn Holash, Gavin Thurston, John S. Rudge, George D. Yancopoulos, Alex A. Adjei, Gabriele Bergers, Bronislaw Pytowski, Mark D. Pegram, Michael S. Gordon	2006	16
6	VEGF Trap Abolishes Shear Stress‐ and Overload‐Dependent Angiogenesis in Skeletal Muscle Microcirculation ·James Williams, Rebecca Greco Koné, John S. Rudge, Stuart Egginton	2006	53
7	Effects of gene delivery on collateral development in chronic hypoperfusion Journal of the American College of Cardiology ·Yi Zhou, Eugenio Stabile, 裕美長谷川, Matie Shou, Richard Baffour, Zu‐Xi Yu, David Rott, George D. Yancopoulos, John S. Rudge, Stephen E. Epstein	2004	25
8	Angiopoietin-1 modulates endothelial cell function and gene expression via the transcription factor FKHR (FOXO1) Genes & Development ·Christopher Daly, Vivian W.Y. Wong, Elena Burova, Yi Wei, Stephanie M. Zabski, Jennifer Griffiths, Ka‐Man Venus Lai, Hsin Chieh Lin, Ella Ioffe, George D. Yancopoulos, John S. Rudge	2004	261
9	Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1α and VEGF Journal of Clinical Investigation ·Vassiliki Poulaki, Wenying Qin, Antonia M. Joussen, Mouna Ben Azaiez, Stanley J. Wiegand, John S. Rudge, George D. Yancopoulos, Anthony P. Adamis	2002	169
10	Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1α and VEGF Journal of Clinical Investigation ·Vassiliki Poulaki, Wenying Qin, Antonia M. Joussen, Mouna Ben Azaiez, Stanley J. Wiegand, John S. Rudge, George D. Yancopoulos, Anthony P. Adamis	2002	10
11	Retinal Vascular Endothelial Growth Factor Induces Intercellular Adhesion Molecule-1 and Endothelial Nitric Oxide Synthase Expression and Initiates Early Diabetic Retinal Leukocyte Adhesion in Vivo American Journal Of Pathology ·Antonia M. Joussen, Vassiliki Poulaki, Wenying Qin, Bernd Kirchhof, Nicholas Mitsiades, Stanley J. Wiegand, John S. Rudge, George D. Yancopoulos, Anthony P. Adamis	2002	320
12	Acute intensive insulin therapy exacerbates diabetic blood-retinal barrier breakdown via hypoxia-inducible factor-1α and VEGF Journal of Clinical Investigation ·Vassiliki Poulaki, Wenying Qin, Antonia M. Joussen, Mouna Ben Azaiez, Stanley J. Wiegand, John S. Rudge, George D. Yancopoulos, Anthony P. Adamis	2002	198
13	Effects of BDNF Infusion on the Regulation of TrkB Protein and Message in Adult Rat Brain Experimental Neurology ·Cornelia M. Yoder, Stanley J. Wiegand, Judith A. Siuciak, Francisco Eduardo Vázquez Tlalolini, John S. Rudge	1997	90
14	Astrocytes Infected with Replication-Defective Adenovirus Containing a Secreted Form of CNTF or NT3 Show Enhanced Support of Neuronal Populationsin Vitro Experimental Neurology ·George M. Smith, Weihua Xu, Elizabeth Pasnikowski, J.M.G. Hendriks, Vivian Wong, John S. Rudge	1996	32
15	CNTF Induces Raphe Neuronal Precursors to Switch from a Serotonergic to a Cholinergic Phenotypein Vitro Molecular and Cellular Neuroscience ·John S. Rudge, Mary J. Eaton, H S Frey, Ronald M. Lindsay, Scott R. Whittemore	1996	52
16	Neurotrophic Factor Receptors and Their Signal Transduction Capabilities in Rat Astrocytes European Journal of Neuroscience ·John S. Rudge, Yanping Li, Elizabeth Pasnikowski, Павел Дмитриевич Корнаухов, Pan Li, George D. Yancopoulos, Stanley J. Wiegand, Ronald M. Lindsay, Nancy Y. Ip	1994	147
17	Injury‐induced Regulation of Ciliary Neurotrophic Factor mRNA in the Adult Rat Brain European Journal of Neuroscience ·Nancy Y. Ip, Stanley J. Wiegand, Joanne K. Morse, John S. Rudge	1993	200
18	Expression of Ciliary Neurotrophic Factor and the Neurotrophins – Nerve Growth Factor, Brain‐Derived Neurotrophic Factor and Neurotrophin 3—in Cultured Rat Hippocampal Astrocytes European Journal of Neuroscience ·John S. Rudge, Ralph Alderson, Elizabeth Pasnikowski, Joyce McClain, Nancy Y. Ip, Ronald M. Lindsay	1992	175
19	Regulation of ciliary neurotrophic factor expression in myelin-related Schwann cells in vivo Neuron ·Beth Friedman, Steven S. Scherer, John S. Rudge, Maureen E. Helgren, Jeremy Schafer, Joyce McClain, S. Di Sano, Stanley J. Wiegand, Daxi Wang, Francisco Eduardo Vázquez Tlalolini, Nancy Y. Ip	1992	277
20	An in vitro model of wound healing in the CNS: Analysis of cell reaction and interaction at different ages Experimental Neurology ·John S. Rudge	1989	78

About John S. Rudge

John S. Rudge is a scholar working on Developmental Neuroscience, Cellular and Molecular Neuroscience, Ophthalmology, Molecular Biology and Internal Medicine, having authored 57 papers that have together received 10.9k indexed citations. Recurring topics across this work include Angiogenesis and VEGF in Cancer (26 papers), Nerve injury and regeneration (10 papers), Neurogenesis and neuroplasticity mechanisms (9 papers), Retinal Diseases and Treatments (6 papers), Lipid metabolism and disorders (6 papers), Cancer, Hypoxia, and Metabolism (5 papers), Reproductive Biology and Fertility (4 papers) and Lymphatic System and Diseases (4 papers). The work is most often cited by research in Developmental Neuroscience (852 citations), Ophthalmology (1.5k citations), Cancer Research (1.9k citations), Molecular Biology (6.4k citations) and Cellular and Molecular Neuroscience (1.7k citations). John S. Rudge has collaborated with scholars based in United States, United Kingdom and Germany. Frequent co-authors include George D. Yancopoulos, Stanley J. Wiegand, Jocelyn Holash, Samuel Davis, Nicholas W. Gale, Ella Ioffe, Susan D. Croll, Donna Hylton, Gavin Thurston and Donald M. McDonald. Their work appears in journals such as European Journal of Neuroscience, Proceedings of the National Academy of Sciences, Experimental Neurology, Developmental Brain Research and Journal of Clinical Investigation.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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