John J. Letterio

15.8k total citations · 4 hit papers
122 papers, 12.8k citations indexed

About

John J. Letterio is a scholar working on Molecular Biology, Oncology and Immunology. According to data from OpenAlex, John J. Letterio has authored 122 papers receiving a total of 12.8k indexed citations (citations by other indexed papers that have themselves been cited), including 71 papers in Molecular Biology, 49 papers in Oncology and 41 papers in Immunology. Recurrent topics in John J. Letterio's work include TGF-β signaling in diseases (48 papers), T-cell and B-cell Immunology (19 papers) and Immune Cell Function and Interaction (17 papers). John J. Letterio is often cited by papers focused on TGF-β signaling in diseases (48 papers), T-cell and B-cell Immunology (19 papers) and Immune Cell Function and Interaction (17 papers). John J. Letterio collaborates with scholars based in United States, United Kingdom and South Korea. John J. Letterio's co-authors include Anita B. Roberts, Marc A. Gavin, Alexander Y. Rudensky, Julien C. Marie, Mizuko Mamura, Andrew G. Geiser, Michael B. Sporn, Lalage M. Wakefield, Ashok B. Kulkarni and Teresa A. Borkowski and has published in prestigious journals such as Nature, Science and New England Journal of Medicine.

In The Last Decade

John J. Letterio

120 papers receiving 12.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

REGULATION OF IMMUNE RESPONSES BY TGF-β

1998 1.6k citations John J. Letterio, Anita B. Roberts profile →
TGF-β1 maintains suppressor function and Foxp3 expression in CD4+CD25+ regulatory T cells

2005 811 citations John J. Letterio et al. The Journal of Experimental Medicine profile →
Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

1999 757 citations John J. Letterio, Sharon M. Wahl et al. profile →
Alex's Lemonade Stand Foundation Infant and Childhood Primary Brain and Central Nervous System Tumors Diagnosed in the United States in 2007–2011

2014 385 citations John J. Letterio et al. profile →

Peers

Countries citing papers authored by John J. Letterio

Since Specialization

Citations

This map shows the geographic impact of John J. Letterio's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John J. Letterio with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John J. Letterio more than expected).

Fields of papers citing papers by John J. Letterio

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John J. Letterio. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John J. Letterio. The network helps show where John J. Letterio may publish in the future.

Co-authorship network of co-authors of John J. Letterio

This figure shows the co-authorship network connecting the top 25 collaborators of John J. Letterio. A scholar is included among the top collaborators of John J. Letterio based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with John J. Letterio. John J. Letterio is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Are NCI Cancer Centers Providing Adolescents and Young Adults With Cancer Focused Clinical Services? A National Survey 2023 ·Journal of the National Comprehensive Cancer Network ·(unknown), (unknown), (unknown), (unknown), Simon Davies, (unknown), (unknown), (unknown), (unknown), Rachel A. Egler, Alex Y. Huang, John J. Letterio, Richard T. Lee	1
2	Development and Functional Characterization of Murine Tolerogenic Dendritic Cells 2018 ·Journal of Visualized Experiments ·(unknown), John J. Letterio, Tej K. Pareek	7
3	Nrf2-mediated metabolic reprogramming of tolerogenic dendritic cells is protective against aplastic anemia 2018 ·Journal of Autoimmunity ·(unknown), Ashish O. Gupta, (unknown), (unknown), John J. Letterio, Tej K. Pareek	29
4	Triterpenoid modulation of IL-17 and Nrf-2 expression ameliorates neuroinflammation and promotes remyelination in autoimmune encephalomyelitis 2011 ·Scientific Reports ·Tej K. Pareek, Abdelmadjid Belkadi, Sashi Kesavapany, Anita Zaremba, (unknown), Lianhua Bai, Mark L. Cohen, Colin J. Meyer, Karen T. Liby, Robert H. Miller, Michael B. Sporn, John J. Letterio	86
5	Cutting Edge: Spontaneous Development of IL-17–Producing γδ T Cells in the Thymus Occurs via a TGF-β1–Dependent Mechanism 2010 ·The Journal of Immunology ·Jeong‐su Do, Pamela J. Fink, Lily Li, Rosanne Spolski, Janet Robinson, Warren J. Leonard, John J. Letterio, Booki Min	113
6	The Synthetic Triterpenoid, CDDO-Me, Modulates the Proinflammatory Response to In Vivo Lipopolysaccharide Challenge 2010 ·Journal of Interferon & Cytokine Research ·Jeffery J. Auletta, (unknown), Byung‐Gyu Kim, Colin J. Meyer, John J. Letterio	27
7	TGF-β1 Inhibits T-bet Induction by IFN-γ in Murine CD4+ T Cells through the Protein Tyrosine Phosphatase Src Homology Region 2 Domain-Containing Phosphatase-1 2005 ·The Journal of Immunology ·(unknown), Leonard D. Shultz, John J. Letterio, James D. Gorham	77
8	Cutting Edge: p27 Kip1 Deficiency Reduces the Requirement for CD28-Mediated Costimulation in Naive CD8+ but Not CD4+ T Lymphocytes 2005 ·The Journal of Immunology ·Lawrence A. Wolfraim, John J. Letterio	16
9	Depressed adrenomedullin in the embryonic transforming growth factor-beta1 null mouse becomes elevated postnatally. 2004 ·The International Journal of Developmental Biology ·(unknown), Alfredo Martı́nez, Laurent Ozbun, Mercedes Garayoa, John J. Letterio, Luis M. Montuenga, Sonia B. Jakowlew	8
10	Transforming Growth Factor-β Production and Myeloid Cells Are an Effector Mechanism through Which CD1d-restricted T Cells Block Cytotoxic T Lymphocyte–mediated Tumor Immunosurveillance 2003 ·The Journal of Experimental Medicine ·Masaki Terabe, So Matsui, (unknown), Mizuko Mamura, Nancy Noben-Trauth, Debra D. Donaldson, Wanjun Chen, Sharon M. Wahl, Steven Ledbetter, Bruce M. Pratt, John J. Letterio, William E. Paul, Jay A. Berzofsky	439
11	Thymosin beta 4 stimulates laminin-5 production independent of TGF-beta 2003 ·Experimental Cell Research ·Gabriel Sosne, (unknown), (unknown), (unknown), Hynda K. Kleinman, John J. Letterio, Linda D. Hazlett, Michelle Kurpakus‐Wheater	65
12	Lifetime exposure to a soluble TGF-β antagonist protects mice against metastasis without adverse side effects 2002 ·Journal of Clinical Investigation ·Yu-an Yang, Oksana I. Dukhanina, Binwu Tang, Mizuko Mamura, John J. Letterio, Jennifer MacGregor, (unknown), Sean Khozin, Zi-yao Liu, Jeffrey Green, Miriam R. Anver, Glenn Merlino, Lalage M. Wakefield	278
13	Disruption of Transforming Growth Factor β Signaling by a Novel Ligand-dependent Mechanism 2002 ·The Journal of Experimental Medicine ·Tania Miñes Fernández, (unknown), (unknown), Gary M. Jones, (unknown), Alexander L. Kovalchuk, Lalage M. Wakefield, Seong‐Jin Kim, Michael Potter, John J. Letterio	28
14	Development and application of fully functional epitope-tagged forms of transforming growth factor-β 2002 ·Journal of Immunological Methods ·Lawrence A. Wolfraim, (unknown), (unknown), (unknown), W. Tony Parks, John J. Letterio	12
15	The Smad3 Protein Is Involved in TGF-β Inhibition of Class II Transactivator and Class II MHC Expression 2001 ·The Journal of Immunology ·Yuanshu Dong, Liping Tang, John J. Letterio, Etty Benveniste	65
16	Autocrine Transforming Growth Factor‐β Growth Pathway in MurineOsteosarcoma Cell Lines Associated with Inability to AffectPhosphorylation of Retinoblastoma Protein 2000 ·Sarcoma ·Fariba Navid, John J. Letterio, Choh Yeung, D. Michiel Pegtel, Lee J. Helman	10
17	Spontaneously increased production of nitric oxide and aberrant expression of the inducible nitric oxide synthase in vivo in the transforming growth factor beta 1 null mouse. 1996 ·The Journal of Experimental Medicine ·Yoram Vodovotz, Andrew G. Geiser, Louis Chesler, John J. Letterio, Andrew Campbell, M. Scott Lucia, Michael B. Sporn, Anita B. Roberts	91
18	The Liver in Transforming Growth Factor-Beta-1 (TGF-β1) Null Mutant Mice 1996 ·Ultrastructural Pathology ·A. Olufemi Williams, Alan Knapton, Andrew G. Geiser, John J. Letterio, Anita B. Roberts	25
19	Early progression of thymocytes along the CD4/CD8 developmental pathway is regulated by a subset of thymic epithelial cells expressing transforming growth factor beta. 1994 ·The Journal of Experimental Medicine ·Yousuke Takahama, John J. Letterio, Hidenori Suzuki, (unknown), Alfred Singer	74
20	Histologic and biochemical correlates of left ventricular chamber dynamics in man 1987 ·Journal of the American College of Cardiology ·Thomas M. Bashore, (unknown), John J. Letterio, Phillip Shaffer, Donald V. Unverferth	88

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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