John de Kruif

4.6k citations

42 papers · 3.2k indexed · 1 hit paper · h-index 26

Impact in

Virology top 2%
- Rabies epidemiology and control
Radiology, Nuclear Medicine and Imaging top 1%
- Monoclonal and Polyclonal Antibodies Research

Papers in

Virology 6
- Rabies epidemiology and control 5
Radiology, Nuclear Medicine and Imaging 29
- Monoclonal and Polyclonal Antibodies Research 29

Co-authors: Ton Logtenberg Jaap Goudsmit Mark Throsby Edwin Boel Jan ter Meulen Alexander B. H. Bakker Wilfred E. Marissen Mandy Jongeneelen
Journals: Cancer Research (5 papers)Journal of Virology (4 papers)Journal of Biological Chemistry (2 papers)Proceedings of the National Academy of Sciences (2 papers)Cancer Cell (2 papers)
Partner nations: Netherlands Germany United States

In The Last Decade

John de Kruif

42 papers receiving 3.0k citations

Hit Papers

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Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells 2008 · 596 citations

Peers

Countries citing papers authored by John de Kruif

Since Specialization

Citations

This map shows the geographic impact of John de Kruif's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by John de Kruif with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites John de Kruif more than expected).

Fields of papers citing papers by John de Kruif

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by John de Kruif. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by John de Kruif. The network helps show where John de Kruif may publish in the future.

Co-authors

The 25 scholars most cited alongside John de Kruif, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with John de Kruif Line = papers co-authored together John de Kruif links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade Cancer Cell ·Cecile Geuijen, Camilla De Nardis, David Maussang, Eric Rovers, Tristan Gallenne, Linda Hendriks, Therèse Visser, Roy Nijhuis, Ton Logtenberg, John de Kruif, Piet Gros, Mark Throsby	2021	2
2	MCLA-117, a CLEC12AxCD3 bispecific antibody targeting a leukaemic stem cell antigen, induces T cell-mediated AML blast lysis Expert Opinion on Biological Therapy ·Pieter Fokko van Loo, Basav N. Hangalapura, Soley Thordardottir, John D. Gibbins, Henrike Veninga, Linda Hendriks, Arjen Kramer, Rob C. Roovers, Marij Leenders, John de Kruif, Robert P. Doornbos, Andres Sirulnik, Mark Throsby, Ton Logtenberg, Harry Dolstra, Alexander B. H. Bakker	2019	47
3	Unbiased Combinatorial Screening Identifies a Bispecific IgG1 that Potently Inhibits HER3 Signaling via HER2-Guided Ligand Blockade Cancer Cell ·Cecile Geuijen, Camilla De Nardis, David Maussang, Eric Rovers, Tristan Gallenne, Linda Hendriks, Therèse Visser, Roy Nijhuis, Ton Logtenberg, John de Kruif, Piet Gros, Mark Throsby	2018	84
4	A new approach for generating bispecific antibodies based on a common light chain format and the stable architecture of human immunoglobulin G1 Journal of Biological Chemistry ·Camilla De Nardis, Linda Hendriks, Emilie Poirier, Tudor Arvinte, Piet Gros, Alexander B. H. Bakker, John de Kruif	2017	71
5	Abstract 32: Preclinical evaluation of MCLA-158: A bispecific antibody targeting LGR5 and EGFR using patient-derived colon carcinoma organoids Cancer Research ·Rob C. Roovers, Bram Herpers, Mark I. James, Berina Eppink, Carme Cortina, David Maussang-Detaille, Ingrid Kolfschoten, Sylvia Boy, Marc van de Wetering, Wim de Lau, Robert P. Doornbos, Kuan Yan, Lucia Salinaro, Lex Bakker, John de Kruif, Hans Clevers, Robert G.J. Vries, Eduard Batlle, Leo Price, Mark Throsby	2017	4
6	Generation of stable cell clones expressing mixtures of human antibodies Biotechnology and Bioengineering ·John de Kruif, Arjen Kramer, Roy Nijhuis, Vanessa van der Zande, Renate den Blanken, Carina Clements, Therèse Visser, Rob Keehnen, Marcel den Hartog, Mark Throsby, Ton Logtenberg	2010	29
7	Construction of Phage Antibody Repertoires from the Blood of West Nile Virus-Infected Donors Methods in molecular biology ·Mark Throsby, John de Kruif	2009	1
8	Heterosubtypic Neutralizing Monoclonal Antibodies Cross-Protective against H5N1 and H1N1 Recovered from Human IgM+ Memory B Cells PLoS ONE ·Mark Throsby, Edward van den Brink, Mandy Jongeneelen, Leo L. M. Poon, Philippe Alard, Lisette A. H. M. Cornelissen, A. Sophie Bakker, Freek Cox, Els van Deventer, Yi Guan, Jindřich Činátl, Jan ter Meulen, Ignace Lasters, Rita Carsetti, Malik Peiris, John de Kruif, Jaap Goudsmit Hit paper breakdown →	2008	596
9	Mapping and analysis of West Nile virus-specific monoclonal antibodies: prospects for vaccine development Expert Review of Vaccines ·Mark Throsby, Jan ter Meulen, Cecile Geuijen, Jaap Goudsmit, John de Kruif	2007	14
10	Comparison of an Anti‐Rabies Human Monoclonal Antibody Combination with Human Polyclonal Anti‐Rabies Immune Globulin The Journal of Infectious Diseases ·Jaap Goudsmit, Wilfred E. Marissen, William C. Weldon, Michael Niezgoda, Cathleen A. Hanlon, Amy B. Rice, John de Kruif, Bernhard Dietzschold, Alexander B. H. Bakker, Charles E. Rupprecht	2006	84
11	Human Monoclonal Antibody Combination against SARS Coronavirus: Synergy and Coverage of Escape Mutants PLoS Medicine ·Jan ter Meulen, Edward N. van den Brink, Leo L. M. Poon, Wilfred E. Marissen, Cynthia Sau-Wai Leung, Freek Cox, Chung Yan Cheung, Arjen Q. Bakker, Johannes A. Bogaards, Els van Deventer, Wolfgang Preiser, Hans Wilhelm Doerr, Vincent Chow, John de Kruif, Malik Peiris, Jaap Goudsmit	2006	366
12	Isolation and Characterization of Human Monoclonal Antibodies from Individuals Infected with West Nile Virus Journal of Virology ·Mark Throsby, Cecile Geuijen, Jaap Goudsmit, Arjen Q. Bakker, Jehanara Korimbocus, R. Arjen Kramer, Marieke Clijsters-van der Horst, Maureen de Jong, Mandy Jongeneelen, Sandra Thijsse, Renate Smit, Therèse Visser, Nora Bijl, Wilfred E. Marissen, Mark Loeb, David J. Kelvin, Wolfgang Preiser, Jan ter Meulen, John de Kruif	2006	135
13	Novel Human Monoclonal Antibody Combination Effectively Neutralizing Natural Rabies Virus Variants and Individual In Vitro Escape Mutants Journal of Virology ·Alexander B. H. Bakker, Wilfred E. Marissen, R. Arjen Kramer, Amy B. Rice, William C. Weldon, Michael Niezgoda, Cathleen A. Hanlon, Sandra Thijsse, Harold H.J. Backus, John de Kruif, Bernhard Dietzschold, Charles E. Rupprecht, Jaap Goudsmit	2005	120
14	The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries European Journal of Immunology ·R. Arjen Kramer, Wilfred E. Marissen, Jaap Goudsmit, Therèse Visser, Marieke Clijsters-van der Horst, Arjen Q. Bakker, Maureen de Jong, Mandy Jongeneelen, Sandra Thijsse, Harold H.J. Backus, Amy B. Rice, William C. Weldon, Charles E. Rupprecht, Bernhard Dietzschold, Alexander B. H. Bakker, John de Kruif	2005	68
15	A proteomic approach to tumour target identification using phage display, affinity purification and mass spectrometry European Journal of Cancer ·Cecilia A.W. Geuijen, Nora Bijl, Renate Smit, Freek Cox, Mark Throsby, Therèse Visser, Mandy Jongeneelen, Alexander B. H. Bakker, Ada M. Kruisbeek, Jaap Goudsmit, John de Kruif	2004	50
16	Human monoclonal antibody as prophylaxis for SARS coronavirus infection in ferrets The Lancet ·Jan ter Meulen, Alexander B. H. Bakker, Edward N. van den Brink, Gerrit Jan Weverling, B Martina, Bart L. Haagmans, Thijs Kuiken, John de Kruif, Wolfgang Preiser, Willy J. M. Spaan, Hans R. Gelderblom, Jaap Goudsmit, Albert D. M. E. Osterhaus	2004	205
17	Leucine Zipper Dimerized Bivalent and Bispecific scFv Antibodies from a Semi-synthetic Antibody Phage Display Library Journal of Biological Chemistry ·John de Kruif, Ton Logtenberg	1996	77
18	New perspectives on recombinant human antibodies Immunology Today ·John de Kruif, A-R. van der Vuurst de Vries, L. Clienti, Edwin Boel, Ton Logtenberg, Willem van Ewijk	1996	27
19	Biosynthetically lipid‐modified human scFv fragments from phage display libraries as targeting molecules for immunoliposomes FEBS Letters ·John de Kruif, Gert Storm, Louis van Bloois, Ton Logtenberg	1996	22
20	Iron-dependent protection of theSynechococcus ferredoxin I transcript against nucleolytic degradation requirescis-regulatory sequences in the 5′ part of the messenger RNA Plant Molecular Biology ·Arnaud Bovy, John de Kruif, Geert de Vrieze, Mies Borrias, Peter Weisbeek	1993	10

About John de Kruif

John de Kruif is a scholar working on Virology, Radiology, Nuclear Medicine and Imaging, Immunology, Molecular Biology and Oncology, having authored 42 papers that have together received 3.2k indexed citations. Recurring topics across this work include Monoclonal and Polyclonal Antibodies Research (29 papers), Glycosylation and Glycoproteins Research (17 papers), Protein purification and stability (6 papers), HER2/EGFR in Cancer Research (5 papers), Rabies epidemiology and control (5 papers), Virology and Viral Diseases (5 papers), Advanced Biosensing Techniques and Applications (5 papers) and T-cell and B-cell Immunology (4 papers). The work is most often cited by research in Virology (329 citations), Radiology, Nuclear Medicine and Imaging (1.3k citations), Infectious Diseases (939 citations), Immunology (699 citations) and Epidemiology (767 citations). John de Kruif has collaborated with scholars based in Netherlands, Germany and United States. Frequent co-authors include Ton Logtenberg, Jaap Goudsmit, Mark Throsby, Edwin Boel, Jan ter Meulen, Alexander B. H. Bakker, Wilfred E. Marissen, Mandy Jongeneelen, Freek Cox and Leo L. M. Poon. Their work appears in journals such as Cancer Research, Journal of Virology, Journal of Biological Chemistry, Proceedings of the National Academy of Sciences and Cancer Cell.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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