Harold H.J. Backus

1.6k citations

23 papers · 1.3k indexed · h-index 17

Oncology top 5%
Molecular Biology
Pulmonary and Respiratory Medicine top 10%
Pathology and Forensic Medicine top 10%
Cancer Research

Co-authors: Godefridus J. Peters Herbert M. Pinedo Gerrit Jansen D. Wouters C.L. van der Wilt Elisabeth Bloemena C.J. van Groeningen Baukelien van Triest
Topics: Colorectal Cancer Treatments and Studies (13 papers)Cancer-related Molecular Pathways (10 papers)Genetic factors in colorectal cancer (7 papers)
Cited by: Oncology Virology Pathology and Forensic Medicine
Journals: Journal of Virology British Journal of Cancer Annals of Oncology
Partner nations: Netherlands United States Sweden

In The Last Decade

Harold H.J. Backus

23 papers receiving 1.3k citations

Peers

Countries citing papers authored by Harold H.J. Backus

Since Specialization

Citations

This map shows the geographic impact of Harold H.J. Backus's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Harold H.J. Backus with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Harold H.J. Backus more than expected).

Fields of papers citing papers by Harold H.J. Backus

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Harold H.J. Backus. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Harold H.J. Backus. The network helps show where Harold H.J. Backus may publish in the future.

Co-authorship network of co-authors of Harold H.J. Backus

This figure shows the co-authorship network connecting the top 25 collaborators of Harold H.J. Backus. A scholar is included among the top collaborators of Harold H.J. Backus based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Harold H.J. Backus. Harold H.J. Backus is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Fast, selective and quantitative protein profiling of adenovirus-vector based vaccines by ultra-performance liquid chromatography 2018 ·Journal of Chromatography A ·(unknown),(unknown),Annemiek Verwilligen,(unknown),Harold H.J. Backus,(unknown),Govert W. Somsen,Cari Sänger van de Griend	6
2	One single, fast and robust capillary electrophoresis method for the direct quantification of intact adenovirus particles in upstream and downstream processing samples 2017 ·Talanta ·(unknown),(unknown),Harold H.J. Backus,(unknown),Govert W. Somsen,Cari Sänger van de Griend	33
3	New capillary gel electrophoresis method for fast and accurate identification and quantification of multiple viral proteins in influenza vaccines 2015 ·Talanta ·(unknown),(unknown),(unknown),(unknown),Harold H.J. Backus,(unknown),Govert W. Somsen,Cari Sänger van de Griend	24
4	Functional Inactivity and Mutations of p53 Differentially Affect Sensitivity to 5-Fluorouracil and Antifolate Inhibitors of Thymidylate Synthase (TS) by Altering TS Levels in Colorectal Cancer Cells 2008 ·Nucleosides Nucleotides & Nucleic Acids ·Elisa Giovannetti,Harold H.J. Backus,D. Wouters,Godefridus J. Peters	5
5	Changes in the status of p53 affect drug sensitivity to thymidylate synthase (TS) inhibitors by altering TS levels 2007 ·British Journal of Cancer ·Elisa Giovannetti,Harold H.J. Backus,D. Wouters,Carlos Gil Ferreira,Viola M. M. van Houten,Ruud H. Brakenhoff,M F Poupon,(unknown),Herbert M. Pinedo,Godefridus J. Peters	69
6	Novel Human Monoclonal Antibody Combination Effectively Neutralizing Natural Rabies Virus Variants and Individual In Vitro Escape Mutants 2005 ·Journal of Virology ·Alexander B. H. Bakker,Wilfred E. Marissen,R. Arjen Kramer,Amy B. Rice,William C. Weldon,Michael Niezgoda,Cathleen A. Hanlon,(unknown),Harold H.J. Backus,John de Kruif,Bernhard Dietzschold,Charles E. Rupprecht,Jaap Goudsmit	120
7	The human antibody repertoire specific for rabies virus glycoprotein as selected from immune libraries 2005 ·European Journal of Immunology ·R. Arjen Kramer,Wilfred E. Marissen,Jaap Goudsmit,Therèse Visser,(unknown),Arjen Q. Bakker,(unknown),Mandy Jongeneelen,(unknown),Harold H.J. Backus,Amy B. Rice,William C. Weldon,Charles E. Rupprecht,Bernhard Dietzschold,Alexander B. H. Bakker,John de Kruif	68
8	Affinity ranking of antibodies using flow cytometry: Application in antibody phage display-based target discovery 2005 ·Journal of Immunological Methods ·(unknown),(unknown),Freek Cox,Pauline M.L. Rood,Mark Throsby,Mandy Jongeneelen,Harold H.J. Backus,(unknown),Ada M. Kruisbeek,Jaap Goudsmit,John de Kruif	24
9	Induction of resistance to the multitargeted antifolate Pemetrexed (ALIMTA) in WiDr human colon cancer cells is associated with thymidylate synthase overexpression 2003 ·Biochemical Pharmacology ·J. Sigmond,Harold H.J. Backus,Dorine Wouters,Olaf H. Temmink,Gerrit Jansen,Godefridus J. Peters	132
10	Thymidylate synthase inhibition triggers apoptosis via caspases-8 and -9 in both wild-type and mutant p53 colon cancer cell lines 2003 ·European Journal of Cancer ·Harold H.J. Backus,D. Wouters,Carlos Gil Ferreira,Viola M. M. van Houten,Ruud H. Brakenhoff,Herbert M. Pinedo,Godefridus J. Peters	49
11	Thymidylate Synthase Inhibition Induces P53 Dependent and Independent Cell Death 2002 ·Advances in experimental medicine and biology ·Harold H.J. Backus,D. Wouters,C.L. van der Wilt,(unknown),Cees J. van Groeningen,(unknown),(unknown),Godefridus J. Peters	5
12	Induction of thymidylate synthase as a 5-fluorouracil resistance mechanism 2002 ·Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease ·Godefridus J. Peters,Harold H.J. Backus,(unknown),Baukelien van Triest,Giovanni Codacci-Pisanelli,C.L. van der Wilt,Kees Smid,John Lunec,A. Hilary Calvert,Sharon Marsh,Howard L. McLeod,Elisabeth Bloemena,Sybren L. Meijer,Gerrit Jansen,C.J. van Groeningen,Herbert M. Pinedo	328
13	Differential expression of cell cycle and apoptosis related proteins in colorectal mucosa, primary colon tumours, and liver metastases 2002 ·Journal of Clinical Pathology ·Harold H.J. Backus,C.J. van Groeningen,W Vos,Danny F. Dukers,Elisabeth Bloemena,D. Wouters,Herbert M. Pinedo,Godefridus J. Peters	63
14	Modulation of both endogenous folates and thymidine enhance the therapeutic efficacy of thymidylate synthase inhibitors. 2001 ·Data Archiving and Networked Services (DANS) ·C.L. van der Wilt,Harold H.J. Backus,Kees Smid,(unknown),G. Veerman,D. Wouters,Daphne Voorn,David G. Priest,Marlene A. Bunni,F. Mitchell,Ann L. Jackman,Gerrit Jansen,Godefridus J. Peters	56
15	Rb, mcl-1 and p53 expression correlate with clinical outcome in patients with liver metastases from colorectal cancer 2001 ·Annals of Oncology ·Harold H.J. Backus,(unknown),C.J. van Groeningen,W Vos,Danny F. Dukers,Elisabeth Bloemena,D. Wouters,H. M. Pinedo,Godefridus J. Peters	54
16	Chemotherapeutic Strategies for Treatment of Colorectal Cancer: Present and Future Developments 2001 ·Clinical Colorectal Cancer ·Harold H.J. Backus,Youcef M. Rustum,(unknown),Godefridus J. Peters	2
17	5-Fluorouracil induced Fas upregulation associated with apoptosis in liver metastases of colorectal cancer patients 2001 ·Annals of Oncology ·Harold H.J. Backus,Danny F. Dukers,C.J. van Groeningen,W Vos,Elisabeth Bloemena,D. Wouters,J.M.G.H. van Riel,Kees Smid,Giuseppe Giaccone,Herbert M. Pinedo,Godefridus J. Peters	56
18	Differences in the induction of DNA damage, cell cycle arrest, and cell death by 5-fluorouracil and antifolates 2000 ·Oncology Reports ·Harold H.J. Backus,Herbert M. Pinedo,D. Wouters,C.M. Kuiper,Gerrit Jansen,C.J. van Groeningen,Godefridus J. Peters	1
19	Molecular downstream events and induction of thymidylate synthase in mutant and wild-type p53 colon cancer cell lines after treatment with 5-fluorouracil and the thymidylate synthase inhibitor raltitrexed 2000 ·European Journal of Cancer ·Godefridus J. Peters,Baukelien van Triest,Harold H.J. Backus,C.M. Kuiper,C.L. van der Wilt,Herbert M. Pinedo	77
20	Folate depletion increases sensitivity of solid tumor cell lines to 5-fluorouracil and antifolates 2000 ·International Journal of Cancer ·Harold H.J. Backus,Herbert M. Pinedo,D. Wouters,José M. Padrón,(unknown),C.L. van der Wilt,C.J. van Groeningen,Gerrit Jansen,Godefridus J. Peters	55

About Harold H.J. Backus

Harold H.J. Backus is a scholar working on Oncology, Virology and Pathology and Forensic Medicine, having authored 23 papers that have together received 1.3k indexed citations. Recurring topics across this work include Colorectal Cancer Treatments and Studies (13 papers), Cancer-related Molecular Pathways (10 papers) and Genetic factors in colorectal cancer (7 papers). The work is most often cited by research in Oncology (609 citations), Virology (101 citations) and Pathology and Forensic Medicine (159 citations). Harold H.J. Backus has collaborated with scholars based in Netherlands, United States and Sweden. Frequent co-authors include Godefridus J. Peters, Herbert M. Pinedo, Gerrit Jansen, D. Wouters, C.L. van der Wilt, Elisabeth Bloemena, C.J. van Groeningen, Baukelien van Triest, Kees Smid and Dorine Wouters. Their work appears in journals such as Journal of Virology, British Journal of Cancer and Annals of Oncology.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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