Edgar A. Otto

21.1k citations

106 papers · 6.3k indexed · 2 hit papers · h-index 42

Impact in

Genetics top 0.2%
- Genetic and Kidney Cyst Diseases
- Genetic Syndromes and Imprinting
Nephrology top 0.5%
- Renal Diseases and Glomerulopathies

Papers in

Nephrology 26
- Renal Diseases and Glomerulopathies 21
Genetics 56
- Genetic and Kidney Cyst Diseases 52
- Genetic Syndromes and Imprinting 15

Co-authors: Friedhelm Hildebrandt Massimo Attanasio Ralf Birkenhäger Matthias T. F. Wolf Julia Hoefele Thomas Boettger Raúl Estévez Thomas J. Jentsch
Journals: Journal of the American Society of Nephrology (13 papers)Kidney International (10 papers)Pediatric Nephrology (8 papers)Nature Genetics (5 papers)Journal of Medical Genetics (5 papers)
Partner nations: United States Germany United Kingdom

In The Last Decade

Edgar A. Otto

103 papers receiving 6.2k citations

Hit Papers

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High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping 2018 · 329 citations

Peers

Countries citing papers authored by Edgar A. Otto

Since Specialization

Citations

This map shows the geographic impact of Edgar A. Otto's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Edgar A. Otto with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Edgar A. Otto more than expected).

Fields of papers citing papers by Edgar A. Otto

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Edgar A. Otto. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Edgar A. Otto. The network helps show where Edgar A. Otto may publish in the future.

Co-authors

The 25 scholars most cited alongside Edgar A. Otto, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Edgar A. Otto Line = papers co-authored together Edgar A. Otto links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	The growth hormone/IGF-1 axis is a risk factor for long-term kidney allograft failure JCI Insight ·Matthew F. Cusick, Viji Nair, Damian Fermin, John R. Hartman, Jeffrey A. Beamish, Zeguo Sun, Zhongyang Zhang, Edgar A. Otto, Rajasree Menon, Gillet, 王大宁, Kelly Shaffer, Peter S. Heeger, Helia Karisani, Madhav C. Menon, Matthias Kretzler, Roger C. Wiggins, Abhijit S. Naik	2025	1
2	Pax protein depletion in proximal tubules triggers conserved mechanisms of resistance to acute ischemic kidney injury preventing transition to chronic kidney disease Kidney International ·Jeffrey A. Beamish, 罗庆雄, F. Ferro-Luzzi, 蔡顺国, Mahboob Chowdhury, D N’Guyen van Nuoï, Edgar A. Otto, Rajasree Menon, Abdul Soofi, Joel M. Weinberg, Sanjeevkumar R. Patel, Gregory R. Dressler	2023	8
3	Sodium glucose co-transporter 2 inhibition increases epidermal growth factor expression and improves outcomes in patients with type 2 diabetes Kidney International ·Taha Sen, Wenjun Ju, Viji Nair, Josolyn Chan, Rajasree Menon, Edgar A. Otto, Laura Pyle, Tim Vigers, Robert G. Nelson, Clare Arnott, Bruce Neal, Michael K. Hansen, Matthias Kretzler, Petter Bjornstad, Hiddo J.L. Heerspink	2023	16
4	SARS-CoV-2 Receptor Networks in Diabetic Kidney Disease, BK Virus Nephropathy, and COVID-19 Associated AKI Journal of the American Society of Nephrology ·Rajasree Menon, Edgar A. Otto, Rachel Sealfon, Viji Nair, Aaron K. Wong, Chandra L. Theesfeld, Hannah Giunta-Stibb, Sayaka Aoki, Jennifer A. Schaub, Céline C. Berthier, Sean Eddy, Chrysta Lienczewski, Chinyere Beatrice Nwosu, Francisco Cabal, Helen C. Looker, Chung-Hsien Yu, Abhijit S. Naik, Robert G. Nelson, Olga G. Troyanskaya, Matthias Kretzler	2020	1
5	Single-cell analysis of progenitor cell dynamics and lineage specification in the human fetal kidney Development ·Rajasree Menon, Edgar A. Otto, María Consuelo Bejarano-Prieto, Jian Zhou, Zidong Zhang, Euisik Yoon, Yu‐Chih Chen, Olga G. Troyanskaya, Jason R. Spence, Matthias Kretzler, Cristina Cebrián	2018	96
6	Biallelic variants in the ciliary gene TMEM67 cause RHYNS syndrome European Journal of Human Genetics ·(unknown), Francesco Brancati, Rui Ding, Steve Protulis, Virginia Vega-Warner, Xiangzhong Zhao, W. Johnson, Irene Bottillo, Marco Castori, Alfredo Caglioti, 강영길, Giuseppe Novelli, Nicola Perrotti, Edgar A. Otto	2018	11
7	High-Throughput Screening Enhances Kidney Organoid Differentiation from Human Pluripotent Stem Cells and Enables Automated Multidimensional Phenotyping Cell stem cell ·Stefan Czerniecki, Nelly M. Cruz, Jennifer L. Harder, Rajasree Menon, James Annis, Edgar A. Otto, Ramila E. Gulieva, Laura Islas, Yong Kyun Kim, Linh M. Tran, Timothy J. Martins, Jeffrey W. Pippin, Hongxia Fu, Matthias Kretzler, Stuart J. Shankland, Jonathan Himmelfarb, Randall T. Moon, Neal Paragas, Benjamin Freedman Hit paper breakdown →	2018	329
8	WDR19 : An ancient, retrograde, intraflagellar ciliary protein is mutated in autosomal recessive retinitis pigmentosa and in Senior‐Loken syndrome Clinical Genetics ·Razek Georges Coussa, Edgar A. Otto, Heon Yung Gee, Vy Ly Phuong Nguyen, Haitao Ren, I. López, Vafa Keser, Qiushi Fu, Ricardo Faingold, Ayesha Khan, Jeremy Schwartzentruber, Jacek Majewski, Friedhelm Hildebrandt, Robert K. Koenekoop	2013	49
9	Genotype–phenotype correlation in 440 patients with NPHP-related ciliopathies Kidney International ·Moumita Chaki, Julia Hoefele, Susan J. Allen, Gokul Ramaswami, Sabine Janssen, Carsten Bergmann, John R. Heckenlively, Edgar A. Otto, Friedhelm Hildebrandt	2011	83
10	Hypomorphic mutations in meckelin (MKS3/TMEM67) cause nephronophthisis with liver fibrosis (NPHP11) Journal of Medical Genetics ·Edgar A. Otto, Kálmán Tory, Massimo Attanasio, Weibin Zhou, Moumita Chaki, Dawid Piątek, Eric L. Wise, Jia-Ji Chen, Boris Utsch, C. Becker, Gudrun Nürnberg, Peter Nürnberg, Ahmet Nayır, Sophie Saunier, Corinne Antignac, Friedhelm Hildebrandt	2009	98
11	Mutations in FN1 cause glomerulopathy with fibronectin deposits Proceedings of the National Academy of Sciences ·Federica Castelletti, Roberta Donadelli, Federica Banterla, Friedhelm Hildebrandt, Peter F. Zipfel, Elena Bresin, Edgar A. Otto, Christine Skerka, Alessandra Renieri, Marta Todeschini, Jessica Caprioli, Rosa Caruso, Rosangela Artuso, Giuseppe Remuzzi, Marina Noris	2008	98
12	Mutation analysis in nephronophthisis using a combined approach of homozygosity mapping, CEL I endonuclease cleavage, and direct sequencing Human Mutation ·Edgar A. Otto, Juliana Helou, Susan J. Allen, John F. O’Toole, Eric L. Wise, Shazia Ashraf, Massimo Attanasio, Weibin Zhou, Matthias T. F. Wolf, Friedhelm Hildebrandt	2007	60
13	Mutational analysis of theNPHP4 gene in 250 patients with nephronophthisis Human Mutation ·Julia Hoefele, Ralf Sudbrak, Richard Reinhardt, S. L. Larson, Steffen Hennig, Anita Imm, Leila Keshavarzi, Boris Utsch, Massimo Attanasio, John F. O’Toole, Edgar A. Otto, Friedhelm Hildebrandt	2005	46
14	Telomeric refinement of the MCKD1 locuson chromosome 1q21 Kidney International ·Matthias T. F. Wolf, Bruno Van Vlem, Hans Christian Hennies, Isabella Zalewski, Stephanie M. Karle, Lamia Ahsan, Komal Sharma, Edgar A. Otto, Arno Fuchshuber, Norbert Lameire, Bart Loeys, Friedhelm Hildebrandt	2004	13
15	Refinement of the critical region for MCKD1 by detection of transcontinental haplotype sharing Kidney International ·Matthias T. F. Wolf, Stephanie M. Karle, Aline Alves da Silva Dias, Oscar Aldana-Assad, Manfred Anlauf, منى التركي, Sabine Kroiss, C. J. Burton, Terry Feest, Edgar A. Otto, Arno Fuchshuber, Friedhelm Hildebrandt	2003	13
16	Mapping of Gene Loci for Nephronophthisis Type 4 and Senior-Løken Syndrome, to Chromosome 1p36 The American Journal of Human Genetics ·G. Valeur, Edgar A. Otto, Nurhayani Hepi Marice Sianipar, Kathrin Saar, Franz Rüschendorf, B.C.P. Polak, Sirpa Ala‐Mello, Julia Hoefele, V. Cimatti, Maria Haller, Heymut Omran, Peter Nürnberg, Friedhelm Hildebrandt	2002	39
17	Identification of a Gene Locus for Senior-Løken Syndrome in the Region of the Nephronophthisis Type 3 Gene Journal of the American Society of Nephrology ·Heymut Omran, M. Murat Naki, Katia Bruhn, (unknown), Heike Olbrich, 冷发光, Edgar A. Otto, Thomas F. Wienker, Rudolf Korinthenberg, M. Brandis, Corinne Antignac, Friedhelm Hildebrandt	2002	25
18	Establishing an algorithm for molecular genetic diagnostics in 127 families with juvenile nephronophthisis Kidney International ·Friedhelm Hildebrandt, (unknown), Christopher Rensing, Regina C. Betz, Ülrike Sommer, Stefanie Birnbaum, Anita Imm, Heymut Omran, M. Leipoldt, Edgar A. Otto	2001	29
19	Barttin is a Cl- channel β-subunit crucial for renal Cl- reabsorption and inner ear K+ secretion Nature ·Raúl Estévez, Thomas Boettger, Valentin Stein, Ralf Birkenhäger, Edgar A. Otto, Friedhelm Hildebrandt, Thomas J. Jentsch	2001	424
20	A deletion distinct from the classical homologous recombination of juvenile nephronophthisis type 1 (NPH1) allows exact molecular definition of deletion breakpoints Human Mutation ·Edgar A. Otto, Regina C. Betz, Christopher Rensing, I Made Yogaswara Dipta, Thomas Kuntzen, Lucca Pazini Meneghel Paiva, Anita Imm, Friedhelm Hildebrandt	2000	16

About Edgar A. Otto

Edgar A. Otto is a scholar working on Nephrology, Genetics, Ophthalmology, Pathology and Forensic Medicine and Molecular Biology, having authored 106 papers that have together received 6.3k indexed citations. Recurring topics across this work include Genetic and Kidney Cyst Diseases (52 papers), Renal and related cancers (44 papers), Renal Diseases and Glomerulopathies (21 papers), Genetic Syndromes and Imprinting (15 papers), Ophthalmology and Eye Disorders (14 papers), Glaucoma and retinal disorders (9 papers), Pediatric Urology and Nephrology Studies (9 papers) and Biomedical Research and Pathophysiology (7 papers). The work is most often cited by research in Genetics (3.5k citations), Nephrology (875 citations), Molecular Biology (4.8k citations), Pediatrics, Perinatology and Child Health (996 citations) and Pathology and Forensic Medicine (796 citations). Edgar A. Otto has collaborated with scholars based in United States, Germany and United Kingdom. Frequent co-authors include Friedhelm Hildebrandt, Massimo Attanasio, Ralf Birkenhäger, Matthias T. F. Wolf, Julia Hoefele, Thomas Boettger, Raúl Estévez, Thomas J. Jentsch, Valentin Stein and Gokul Ramaswami. Their work appears in journals such as Journal of the American Society of Nephrology, Kidney International, Pediatric Nephrology, Nature Genetics and Journal of Medical Genetics.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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