Jack Hinson

9.3k total citations · 2 hit papers
102 papers, 7.5k citations indexed

About

Jack Hinson is a scholar working on Pharmacology, Hepatology and Oncology. According to data from OpenAlex, Jack Hinson has authored 102 papers receiving a total of 7.5k indexed citations (citations by other indexed papers that have themselves been cited), including 81 papers in Pharmacology, 32 papers in Hepatology and 28 papers in Oncology. Recurrent topics in Jack Hinson's work include Drug-Induced Hepatotoxicity and Protection (69 papers), Pharmacogenetics and Drug Metabolism (37 papers) and Drug Transport and Resistance Mechanisms (28 papers). Jack Hinson is often cited by papers focused on Drug-Induced Hepatotoxicity and Protection (69 papers), Pharmacogenetics and Drug Metabolism (37 papers) and Drug Transport and Resistance Mechanisms (28 papers). Jack Hinson collaborates with scholars based in United States, Russia and Czechia. Jack Hinson's co-authors include Laura P. James, Philip R. Mayeux, Neil R. Pumford, Dean W. Roberts, Sandra McCullough, James R. Gillette, B Ketterer, Brian Coles, Lance R. Pohl and Hartmut Jaeschke and has published in prestigious journals such as Nature, Journal of Biological Chemistry and Gastroenterology.

In The Last Decade

Jack Hinson

100 papers receiving 7.2k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

ACETAMINOPHEN-INDUCED HEPATOTOXICITY

2003 848 citations Laura P. James, Philip R. Mayeux et al. Drug Metabolism and Disposition profile →
Mechanisms of Acetaminophen-Induced Liver Necrosis

2009 725 citations Jack Hinson, Dean W. Roberts et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Jack Hinson United States	47	4.8k	1.9k	1.7k	1.6k	945	102	7.5k
Harihara M. Mehendale United States	45	3.1k 0.6×	1.6k 0.8×	1.7k 1.0×	1.1k 0.7×	1.1k 1.2×	266	6.7k
M. Teresa Donato Spain	46	2.8k 0.6×	1.7k 0.9×	2.3k 1.4×	1.5k 0.9×	1.2k 1.3×	143	7.4k
Sidney D. Nelson United States	53	6.5k 1.3×	1.2k 0.6×	2.9k 1.7×	2.4k 1.5×	724 0.8×	213	10.8k
Anup Ramachandran United States	49	4.1k 0.8×	2.3k 1.2×	2.3k 1.4×	1.1k 0.7×	1.7k 1.8×	136	7.8k
Edward L. LeCluyse United States	58	4.5k 0.9×	2.0k 1.0×	3.0k 1.8×	3.2k 2.1×	679 0.7×	135	11.3k
Mitchell R. McGill United States	42	4.4k 0.9×	2.3k 1.2×	1.7k 1.0×	1.3k 0.8×	1.9k 2.0×	100	7.1k
Lance R. Pohl United States	44	3.1k 0.6×	913 0.5×	1.2k 0.7×	986 0.6×	569 0.6×	114	5.4k
Philip S. Guzelian United States	56	5.9k 1.2×	880 0.5×	2.4k 1.4×	3.5k 2.2×	532 0.6×	120	10.1k
David J. Jollow United States	37	7.2k 1.5×	1.7k 0.9×	2.7k 1.6×	2.4k 1.6×	1.0k 1.1×	94	12.7k
Patricia E. Ganey United States	40	2.2k 0.4×	875 0.5×	1.1k 0.6×	821 0.5×	666 0.7×	128	4.5k

Countries citing papers authored by Jack Hinson

Since Specialization

Citations

This map shows the geographic impact of Jack Hinson's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Jack Hinson with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Jack Hinson more than expected).

Fields of papers citing papers by Jack Hinson

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Jack Hinson. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Jack Hinson. The network helps show where Jack Hinson may publish in the future.

Co-authorship network of co-authors of Jack Hinson

This figure shows the co-authorship network connecting the top 25 collaborators of Jack Hinson. A scholar is included among the top collaborators of Jack Hinson based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Jack Hinson. Jack Hinson is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Roberts, Dean W., William M. Lee, Jack Hinson, et al.. (2016). An Immunoassay to Rapidly Measure Acetaminophen Protein Adducts Accurately Identifies Patients With Acute Liver Injury or Failure. Clinical Gastroenterology and Hepatology. 15(4). 555–562.e3. 51 indexed citations

Banerjee, Sudeep, Stepan B. Melnyk, Kimberly J. Krager, et al.. (2015). The neuronal nitric oxide synthase inhibitor NANT blocks acetaminophen toxicity and protein nitration in freshly isolated hepatocytes. Free Radical Biology and Medicine. 89. 750–757. 36 indexed citations

Yang, Xi, James Greenhaw, Qiang Shi, et al.. (2012). Mouse Liver Protein Sulfhydryl Depletion after Acetaminophen Exposure. Journal of Pharmacology and Experimental Therapeutics. 344(1). 286–294. 15 indexed citations

Yuan, Qingxin, Wei Tang, Xiaoping Zhang, et al.. (2012). Proinsulin Atypical Maturation and Disposal Induces Extensive Defects in Mouse Ins2+/Akita β-Cells. PLoS ONE. 7(4). e35098–e35098. 16 indexed citations

McCullough, Sandra, Jack Hinson, Richard C. Kurten, et al.. (2011). Echinomycin Decreases Induction of Vascular Endothelial Growth Factor and Hepatocyte Regeneration in Acetaminophen Toxicity in Mice. Basic & Clinical Pharmacology & Toxicology. 110(4). 327–334. 7 indexed citations

Abdel‐Rahman, Susan M., Aliza Brown, Sandra McCullough, et al.. (2010). Indocyanine green clearance varies as a function of N-acetylcysteine treatment in a murine model of acetaminophen toxicity. Chemico-Biological Interactions. 189(3). 222–229. 13 indexed citations

MacMillan-Crow, Lee Ann, Tonya Rafferty, Hamida Saba, et al.. (2010). Acetaminophen-Induced Hepatotoxicity in Mice Occurs with Inhibition of Activity and Nitration of Mitochondrial Manganese Superoxide Dismutase. Journal of Pharmacology and Experimental Therapeutics. 337(1). 110–116. 90 indexed citations

Redeker, Kelly R., et al.. (2007). Mechanisms of Chloroform-Induced Hepatotoxicity: Oxidative Stress and Mitochondrial Permeability Transition in Freshly Isolated Mouse Hepatocytes. Journal of Toxicology and Environmental Health. 70(22). 1936–1945. 21 indexed citations

Kurten, Richard C., et al.. (2005). Mechanisms of Acetaminophen-Induced Hepatotoxicity: Role of Oxidative Stress and Mitochondrial Permeability Transition in Freshly Isolated Mouse Hepatocytes. Journal of Pharmacology and Experimental Therapeutics. 312(2). 509–516. 255 indexed citations

10.

James, Laura P., Richard C. Kurten, Laura W. Lamps, Sandra McCullough, & Jack Hinson. (2005). Tumour Necrosis Factor Receptor 1 and Hepatocyte Regeneration in Acetaminophen Toxicity: A Kinetic Study of Proliferating Cell Nuclear Antigen and Cytokine Expression. Basic & Clinical Pharmacology & Toxicology. 97(1). 8–14. 43 indexed citations

11.

James, Laura P., Pippa Simpson, Henry C. Farrar, et al.. (2005). Cytokines and Toxicity in Acetaminophen Overdose. The Journal of Clinical Pharmacology. 45(10). 1165–1171. 66 indexed citations

12.

Hinson, Jack, et al.. (2004). Acetaminophen‐Induced Hepatotoxicity: Role of Metabolic Activation, Reactive Oxygen/Nitrogen Species, and Mitochondrial Permeability Transition. Drug Metabolism Reviews. 36(3-4). 805–822. 253 indexed citations

13.

Gujral, Jaspreet S., Jack Hinson, & Hartmut Jaeschke. (2004). Chlorotyrosine protein adducts are reliable biomarkers of neutrophil-induced cytotoxicity in vivo. PubMed. 3(S1). S48–S48. 31 indexed citations

14.

Gujral, Jaspreet S., Jack Hinson, Anwar Farhood, & Hartmut Jaeschke. (2004). NADPH oxidase-derived oxidant stress is critical for neutrophil cytotoxicity during endotoxemia. American Journal of Physiology-Gastrointestinal and Liver Physiology. 287(1). G243–G252. 93 indexed citations

15.

James, Laura P., Philip R. Mayeux, & Jack Hinson. (2003). ACETAMINOPHEN-INDUCED HEPATOTOXICITY. Drug Metabolism and Disposition. 31(12). 1499–1506. 848 indexed citations breakdown →

16.

Pumford, Neil R., et al.. (1999). Pretreatment of mice with macrophage inactivators decreases acetaminophen hepatotoxicity and the formation of reactive oxygen and nitrogen species. Hepatology. 30(1). 186–195. 284 indexed citations

17.

Hinson, Jack, et al.. (1996). Immunochemical Detection of Drug-Protein Adducts in Acetaminophen Hepatotoxicity. Advances in experimental medicine and biology. 387. 47–55. 7 indexed citations

18.

Bryant, Matthew, et al.. (1994). 2,6-Dimethylaniline—hemoglobin adducts from lidocaine in humans. Carcinogenesis. 15(10). 2287–2290. 46 indexed citations

19.

Hinson, Jack, et al.. (1994). The Role of Metabolic Activation in Drug Toxicity. Drug Metabolism Reviews. 26(1-2). 395–412. 52 indexed citations

20.

Weeks, Benjamin S., Paul H. Gamache, Norman W. Klein, et al.. (1990). Acetaminophen toxicity to cultured rat embryos. Teratogenesis Carcinogenesis and Mutagenesis. 10(5). 361–371. 8 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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