Henry J. Breslin

1.6k total citations · 1 hit paper
27 papers, 1.4k citations indexed

About

Henry J. Breslin is a scholar working on Organic Chemistry, Molecular Biology and Infectious Diseases. According to data from OpenAlex, Henry J. Breslin has authored 27 papers receiving a total of 1.4k indexed citations (citations by other indexed papers that have themselves been cited), including 11 papers in Organic Chemistry, 11 papers in Molecular Biology and 9 papers in Infectious Diseases. Recurrent topics in Henry J. Breslin's work include HIV/AIDS drug development and treatment (9 papers), Neuropeptides and Animal Physiology (6 papers) and HIV Research and Treatment (5 papers). Henry J. Breslin is often cited by papers focused on HIV/AIDS drug development and treatment (9 papers), Neuropeptides and Animal Physiology (6 papers) and HIV Research and Treatment (5 papers). Henry J. Breslin collaborates with scholars based in United States and Belgium. Henry J. Breslin's co-authors include Michael J. Kukla, Rudi Pauwels, M. Janssen, Erik De Clercq, Koen Andries, Paul A. J. Janssen, Robert Woestenborghs, Jan Desmyter, Dominique Schols and J. Heykants and has published in prestigious journals such as Nature, Journal of Medicinal Chemistry and Antimicrobial Agents and Chemotherapy.

In The Last Decade

Henry J. Breslin

26 papers receiving 1.4k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives

1990 673 citations Rudi Pauwels, Koen Andries et al. Nature profile →

Peers

Countries citing papers authored by Henry J. Breslin

Since Specialization

Citations

This map shows the geographic impact of Henry J. Breslin's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Henry J. Breslin with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Henry J. Breslin more than expected).

Fields of papers citing papers by Henry J. Breslin

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Henry J. Breslin. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Henry J. Breslin. The network helps show where Henry J. Breslin may publish in the future.

Co-authorship network of co-authors of Henry J. Breslin

This figure shows the co-authorship network connecting the top 25 collaborators of Henry J. Breslin. A scholar is included among the top collaborators of Henry J. Breslin based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Henry J. Breslin. Henry J. Breslin is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Identification of a dual δ OR antagonist/μ OR agonist as a potential therapeutic for diarrhea-predominant Irritable Bowel Syndrome (IBS-d) 2012 ·Bioorganic & Medicinal Chemistry Letters ·Henry J. Breslin, Craig J. Diamond, Robert W. Kavash, Chaozhong Cai, Alexey B. Dyatkin, (unknown), Sui‐Po Zhang, Paul R. Wade, Pamela J. Hornby, Wei He	37
2	2,7-Pyrrolo[2,1-f][1,2,4]triazines as JAK2 inhibitors: Modification of target structure to minimize reactive metabolite formation 2011 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Mark S. Albom, Thelma S. Angeles, Henry J. Breslin, Diane E. Gingrich, Zeqi Huang, Joseph G. Lisko, Jennifer L. Mason, Karen L. Milkiewicz, (unknown), Ted L. Underiner, Gregory J. Wells, Kevin J. Wells‐Knecht, Bruce D. Dorsey	17
3	2,7-Disubstituted-Pyrrolotriazine Kinase Inhibitors with an Unusually High Degree of Reactive Metabolite Formation 2011 ·Chemical Research in Toxicology ·Kevin J. Wells‐Knecht, Gregory R. Ott, Mangeng Cheng, Gregory J. Wells, Henry J. Breslin, Diane E. Gingrich, (unknown), Eugen F. Mesaros, Zeqi Huang, Mehran Yazdanian, Mark A. Ator, Lisa D. Aimone, (unknown), Bruce D. Dorsey	8
4	Optimization of a novel kinase inhibitor scaffold for the dual inhibition of JAK2 and FAK kinases 2011 ·Bioorganic & Medicinal Chemistry Letters ·Craig A. Zificsak, Diane E. Gingrich, Henry J. Breslin, Derek Dunn, Karen L. Milkiewicz, Jay Theroff, (unknown), Ted L. Underiner, (unknown), Lisa D. Aimone, Mark S. Albom, Jennifer L. Mason, (unknown), Jean Husten, Thelma S. Angeles, James P. Finn, (unknown), Teresa M. O’Kane, Paweł Dobrzański, Bruce D. Dorsey	18
5	Identification of potent phenyl imidazoles as opioid receptor agonists 2006 ·Bioorganic & Medicinal Chemistry Letters ·Henry J. Breslin, Chaozhong Cai, (unknown), Santosh V. Coutinho, Sui‐Po Zhang, Pamela J. Hornby, Wei He	21
6	Inhibitor-based validation of a homology model of the active-site of tripeptidyl peptidase II 2005 ·Journal of Molecular Graphics and Modelling ·Hans De Winter, Henry J. Breslin, (unknown), Robert W. Kavash, Marijke Somers	5
7	Novel triazole based inhibitors of Ras farnesyl transferase 2005 ·Bioorganic & Medicinal Chemistry Letters ·Ashis Saha, Li Liu, (unknown), (unknown), Christophe Meyer, (unknown), Henry J. Breslin, Michael J. Kukla, D End	22
8	A convenient, large-scale synthesis of 4′-carboxamido N-Boc-2′,6′-dimethyl-l-phenylalanines 2005 ·Tetrahedron ·Chaozhong Cai, Henry J. Breslin, Wei He	5
9	Tripeptidyl-peptidase II (TPP II) inhibitory activity of ( S )-2,3-dihydro-2-(1 H -imidazol-2-yl)-1 H -indoles, a systematic SAR evaluation. Part 2 2003 ·Bioorganic & Medicinal Chemistry Letters ·Henry J. Breslin, (unknown), Michael J. Kukla, Hans De Winter, (unknown), Peter Roevens, Robert W. Kavash	15
10	Synthesis and anti-HIV activity of 1,3,4,5-tetrahydro-2H-1,4-benzodiazepin-2-one (TBO) derivatives. truncated 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-ones (TIBO) analogues 1999 ·Bioorganic & Medicinal Chemistry ·Henry J. Breslin, Michael J. Kukla, (unknown), (unknown), (unknown), Rudi Pauwels, Koen Andries, Erik De Clercq, M. Janssen, (unknown)	20
11	Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TlBO) Derivatives. 4 1995 ·Journal of Medicinal Chemistry ·Winston G. Ho, Michael J. Kukla, Henry J. Breslin, Donald Ludovici, (unknown), Craig J. Diamond, Milton Edson Miranda, James D. Rodgers, Chih Y. Ho	52
12	Synthesis and Anti-HIV-1 Activity of 4,5,6,7-Tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) Derivatives. 3 1995 ·Journal of Medicinal Chemistry ·Henry J. Breslin, Michael J. Kukla, Donald Ludovici, Richard J. Mohrbacher, Winston G. Ho, Milton Edson Miranda, James D. Rodgers, T. Kevin Hitchens, Gregory C. Leo	85
13	A novel series of N-(1-aminoalkylidene)carboximidamides as potential hypoglycemia agents 1993 ·Journal of Medicinal Chemistry ·Henry J. Breslin, Michael J. Kukla, Robert W. Tuman, (unknown), Charles R. Bowden	11
14	Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives 1991 ·Journal of Medicinal Chemistry ·Michael J. Kukla, Henry J. Breslin, Rudi Pauwels, (unknown), (unknown), Malcolm K. Scott, Ronald G. Sherrill, (unknown), (unknown)	79
15	Synthesis and anti-HIV-1 activity of 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepin-2(1H)-one (TIBO) derivatives. 2 1991 ·Journal of Medicinal Chemistry ·Michael J. Kukla, Henry J. Breslin, Craig J. Diamond, (unknown), Chih Y. Ho, Milton Edson Miranda, James D. Rodgers, Ronald G. Sherrill, Erik De Clercq, Rudi Pauwels, Koen Andries, Luc Moëns, M. Janssen, Paul A. J. Janssen	146
16	Electron impact mass spectra of novel tetrahydroimidazo [4, 5, l‐jk] [1, 4]benzodiazepin‐2(1H)‐one derivatives 1991 ·Organic Mass Spectrometry ·Gary W. Caldwell, Michael J. Kukla, John A. Masucci, Henry J. Breslin, William J. Jones, Diane A. Gauthier, (unknown)	4
17	Potent and selective inhibition of HIV-1 replication in vitro by a novel series of TIBO derivatives breakdown → 1990 ·Nature ·Rudi Pauwels, Koen Andries, Jan Desmyter, Dominique Schols, Michael J. Kukla, Henry J. Breslin, (unknown), (unknown), Robert Woestenborghs, J. Heykants, K H Schellekens, M. Janssen, Erik De Clercq, Paul A. J. Janssen	673
18	Antihypertensive dihydropyridines with 1,4,4-trisubstitution 1990 ·Journal of Medicinal Chemistry ·Michael J. Kukla, Henry J. Breslin, Alan Gill	6
19	Polycyclic heterocycles from glutaraldehyde in one reaction 1987 ·The Journal of Organic Chemistry ·Michael J. Kukla, Henry J. Breslin	16
20	Synthesis, characterization, and anorectic testing of the four stereoisomers of cyclo(histidylproline) 1985 ·Journal of Medicinal Chemistry ·Michael J. Kukla, Henry J. Breslin, Charles R. Bowden	19

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact