J E Leysen

2.1k citations

20 papers · 1.8k indexed · 1 hit paper · h-index 13

Impact in

Cellular and Molecular Neuroscience top 1%
- Neurotransmitter Receptor Influence on Behavior
- Neuroscience and Neuropharmacology Research
- Neuropeptides and Animal Physiology
Biological Psychiatry top 10%

Papers in ⓘ

Molecular Biology 15
- Receptor Mechanisms and Signaling 10
- Chemical Synthesis and Analysis 4
- Pharmacological Receptor Mechanisms and Effects 2
- Ion channel regulation and function 2
- Nicotinic Acetylcholine Receptors Study 2
Cellular and Molecular Neuroscience 9
- Neurotransmitter Receptor Influence on Behavior 5
- Neuropeptides and Animal Physiology 4
- Neuroscience and Neuropharmacology Research 4

Co-authors: C. J. E. Niemegeers (1 shared paper)Pierre M. Laduron (1 shared paper)Jan M. Van Nueten (1 shared paper)Alain Schotte (4 shared papers)Anton A. H. P. Megens (1 shared paper)W Gommeren (4 shared papers)Petrus J. Pauwels (2 shared papers)P.F.M. Janssen (2 shared papers)
Journals: Molecular Pharmacology (3 papers)Journal of Pharmacology and Experimental Therapeutics (1 paper)Life Sciences (1 paper)Regulatory Peptides (1 paper)Journal of Affective Disorders (1 paper)
Partner nations: Belgium United States France

In The Last Decade

J E Leysen

20 papers receiving 1.7k citations

Hit Papers

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[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role. 1982 · 982 citations

Peers

Countries citing papers authored by J E Leysen

Since Specialization

Citations

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Fields of papers citing papers by J E Leysen

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J E Leysen. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J E Leysen. The network helps show where J E Leysen may publish in the future.

Co-authors

The 25 scholars most cited alongside J E Leysen, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J E Leysen Line = papers co-authored together J E Leysen links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	[3H]Ketanserin (R 41 468), a selective 3H-ligand for serotonin2 receptor binding sites. Binding properties, brain distribution, and functional role. Molecular Pharmacology ·J E Leysen, C. J. E. Niemegeers, Jan M. Van Nueten, Pierre M. Laduron Hit paper breakdown →	1982	982
2	Interaction of antipsychotic drugs with neurotransmitter receptor sites in vitro and in vivo in relation to pharmacological and clinical effects: role of 5HT2 receptors Psychopharmacology ·J E Leysen, Paul M. F. Janssen, Alain Schotte, Walter H. M. L. Luyten, Anton A. H. P. Megens	1993	281
3	Serotonin-S2 receptor binding sites and functional correlates Neuropharmacology ·J E Leysen	1984	116
4	In vitro and in vivo binding characteristics of a new long-acting histamine H1 antagonist, astemizole. Molecular Pharmacology ·P M Laduron, P.F.M. Janssen, W Gommeren, J E Leysen	1982	88
5	Lubeluzole, a novel long-term neuroprotectant, inhibits the glutamate-activated nitric oxide synthase pathway. Journal of Pharmacology and Experimental Therapeutics ·Anne Lesage, Luc Peeters, J E Leysen	1996	59
6	5‐HT₂ Receptors, Roles and Regulation Annals of the New York Academy of Sciences ·J E Leysen, Petrus J. Pauwels	1990	50
7	5HT1B and 5HT1D receptor mRNA differential co-localization with peptide mRNA in the guinea pig trigeminal ganglion Neuroreport ·Pascal Bonaventure, Pieter Voorn, Walter Luyten, J E Leysen	1998	37
8	Autoradiographic mapping of 5-HT1B- and 5-HT1D receptors in human brain using [3H]alniditan, a new radioligand. PubMed ·Pascal Bonaventure, Alain Schotte, Patrick Cras, J E Leysen	1997	37
9	Binding of [3H]paroxetine to platelets of depressed patients: seasonal differences and effects of diagnostic classification Journal of Affective Disorders ·Peter D'Hondt, Michaël Maes, J E Leysen, W Gommeren, Simon Scharpé, Paul Cosyns	1994	33
10	Etomidate stereospecifically stimulates forebrain, but not cerebellar, 3H-diazepam binding Life Sciences ·D. Ashton, R Geerts, C. Waterkeyn, J E Leysen	1981	30
11	Identification of 5-HT2 receptors, α1-adrenoceptors and amine release sites in rat brain by autoradiography with [125I]7-amino-8-iodo-ketanserin European Journal of Pharmacology Molecular Pharmacology ·Alain Schotte, J E Leysen	1989	20
12	Synthesis and biological activities of linear and cyclic enkephalin analogues containing a Ψ (E,CH=CH) or Ψ (CH₂CH₂) isosteric replacement International journal of peptide & protein research ·Dirk Tourwé, J. Couder, Marc Ceusters, D. Meert, Thomas F. Burks, Thomas H. Kramer, Peg Davis, Richard J. Knapp, Henry I. Yamamura, J E Leysen, G. Van Binst	1992	15
13	Receptor cloning and heterologous expression — towards a new tool for drug discovery Trends in biotechnology ·Walter Luyten, J E Leysen	1993	12
14	Depolarization of chick myotubes triggers the appearance of (+)-[3H]PN 200-110-binding sites. Molecular Pharmacology ·Petrus J. Pauwels, Harrie P. van Assouw, J E Leysen	1987	12
15	β-Adrenoceptor-mediated cAMP accumulation in cardiac cells: effects of nebivolol European Journal of Pharmacology Molecular Pharmacology ·Petrus J. Pauwels, J E Leysen, Paul A. J. Janssen	1989	9
16	Towards an improved survival of rat brain neurons in culture by cerebrospinal fluid of patients with senile dementia of Alzheimer's type Brain Research ·Petrus J. Pauwels, Harrie P. van Assouw, Marc De Ryck, J E Leysen, R. Dom, Dominique Van Gool	1993	8
17	Reconstitution of human 5-hydroxytryptamine5A receptor--G protein coupling in E. coli and Sf9 cell membranes with membranes from Sf9 cells expressing mammalian G proteins. PubMed ·Bart J. B. Francken, Jurgen F.M. Vanhauwe, Katty Josson, Mirek Jurzak, Walter Luyten, J E Leysen	2001	8
18	[Non-sedative antihistaminics and binding to central and peripheral H1 histamine receptors]. PubMed ·J E Leysen, W Gommeren, P.F.M. Janssen, G Sánz, J. M. Gillardin, Alain Schotte, Paul A. J. Janssen	1991	4
19	Demonstration of a complex subunit composition of a unitary dopamine receptor: effects of lesions and proteolytic enzymes on stereospecific binding. PubMed ·J E Leysen, W Gommeren, Paul Van Gompel	1983	2
20	Radioligand binding profile of enantiomers of tifluadom analogues for opioid, CCK and central benzodiazepine receptors: Versatility of the benzodiazepine skeleton Regulatory Peptides ·R. L. Meurisse, Lieve Heylen, J E Leysen, J.C. Meunier, C. De Ranter	1994	1

About J E Leysen

J E Leysen is a scholar working on Molecular Biology, Cellular and Molecular Neuroscience, Organic Chemistry, Radiology, Nuclear Medicine and Imaging and Physiology, having authored 20 papers that have together received 1.8k indexed citations. Recurring topics across this work include Receptor Mechanisms and Signaling (10 papers), Neurotransmitter Receptor Influence on Behavior (5 papers), Neuropeptides and Animal Physiology (4 papers), Chemical Synthesis and Analysis (4 papers), Neuroscience and Neuropharmacology Research (4 papers), Pharmacological Receptor Mechanisms and Effects (2 papers), Ion channel regulation and function (2 papers) and Nicotinic Acetylcholine Receptors Study (2 papers). The work is most often cited by research in Cellular and Molecular Neuroscience (1.2k citations), Biological Psychiatry (61 citations), Psychiatry and Mental health (282 citations), Behavioral Neuroscience (48 citations) and Molecular Biology (920 citations). J E Leysen has collaborated with scholars based in Belgium, United States and France. Frequent co-authors include C. J. E. Niemegeers, Pierre M. Laduron, Jan M. Van Nueten, Alain Schotte, Anton A. H. P. Megens, W Gommeren, Petrus J. Pauwels, P.F.M. Janssen, P M Laduron and Luc Peeters. Their work appears in journals such as Molecular Pharmacology, Journal of Pharmacology and Experimental Therapeutics, Life Sciences, Regulatory Peptides and Journal of Affective Disorders.

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