J. Breed

4.8k citations

51 papers · 3.4k indexed · h-index 34

Molecular Biology top 5%
- Lipid Membrane Structure and Behavior 6
- Chemical Synthesis and Analysis 5
- Protein Structure and Dynamics 4
- Biochemical and Molecular Research 4
Immunology and Allergy top 5%
Oncology top 5%
- Cancer-related Molecular Pathways 4
Organic Chemistry top 5%
Microbiology top 5%
Materials Chemistry
- Enzyme Structure and Function 5
Cell Biology
- Microtubule and mitosis dynamics 4
Spectroscopy
- Mass Spectrometry Techniques and Applications 4

Co-authors: Mark S.P. Sansom Ian D. Kerr Ramasubbu Sankararamakrishnan Richard A. Norman Wolfram Welte Oliver S. Smart Kay Diederichs Graham R. Smith
Cited by: Molecular Biology Immunology and Allergy Oncology
Journals: Bioorganic & Medicinal Chemistry Letters (7 papers)Biophysical Journal (6 papers)Journal of Medicinal Chemistry (4 papers)
Partner nations: United Kingdom Germany United States

In The Last Decade

J. Breed

51 papers receiving 3.3k citations

Peers

Countries citing papers authored by J. Breed

Since Specialization

Citations

This map shows the geographic impact of J. Breed's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by J. Breed with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites J. Breed more than expected).

Fields of papers citing papers by J. Breed

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by J. Breed. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by J. Breed. The network helps show where J. Breed may publish in the future.

Co-authorship network

The 25 scholars most cited alongside J. Breed, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with J. Breed Line = papers co-authored together J. Breed links everyone, so they are left out of the graph.

All Works

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20 of 20 papers shown

#	Work
1	Cryo-EM structure determination of small therapeutic protein targets at 3 Å-resolution using a rigid imaging scaffold Proceedings of the National Academy of Sciences ·Roger Castells‐Graells,Yan Tao-ha,Mark A. Arbing,M.R. Sawaya,G. R. EVANS,Duilio Cascio,Emma S. Gleave,J.E. Debreczeni,J. Breed,Karoline Leopold,Hieu T. Dang,Dushyant Jahagirdar,Angallo P Acqua,Sriram Subramaniam,Chris Phillips,Todd O. Yeates	2023	21
2	MTH1 Substrate Recognition—An Example of Specific Promiscuity PLoS ONE ·J. Willem M. Nissink,Michał Biśta,J. Breed,Martin Sean,Kevin J. Embrey,JEANNE‐MARIE LECOMTE,Arif Ramadhan	2016	19
3	Structural Characterisation Reveals Mechanism of IL-13-Neutralising Monoclonal Antibody Tralokinumab as Inhibition of Binding to IL-13Rα1 and IL-13Rα2 Journal of Molecular Biology ·Bojana Popovic,J. Breed,D. Gareth Rees,Matthew Gardener,Hermann Kees,Benjamin Kemp,Jennifer Spooner,Jennifer Keen,Ralph Minter,Alexander Ziepke,Gene Colice,Daniel DeMaria,Tristan J. Vaughan,Richard May	2016	143
4	Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology Proceedings of the National Academy of Sciences ·Holly H. Soutter,Matthew Clark,John W. Cuozzo,Christoph E. Dumelin,Marie-Aude Guié,Sevan Habeshian,Anthony D. Keefe,A. Feizabadi,Eric A. Sigel,Dawn M. Troast,Ying Zhang,Andrew D. Ferguson,Gareth M. Davies,Andrielle Adelina Teodoro Jesus,J. Breed,Prashanti Madhavapeddi,Jon Read	2016	46
5	Structural Insights into FGFR Kinase Isoform Selectivity: Diverse Binding Modes of AZD4547 and Ponatinib in Complex with FGFR1 and FGFR4 Structure ·Julie A. Tucker,Tobias Klein,J. Breed,Alexander L. Breeze,R. Overman,Chris Phillips,Richard A. Norman	2014	97
6	Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series Bioorganic & Medicinal Chemistry Letters ·Spencer Hupp,Andrew R. McKenzie,Adam B. Shapiro,Ludovic R. Otterbein,Haihong Ni,Haonan Gong,S. Stokes,Robert Albert,Sameer Kawatkar,J. Breed	2012	24
7	Synthesis and evaluation of triazolones as checkpoint kinase 1 inhibitors Bioorganic & Medicinal Chemistry Letters ·Vibha Oza,Susan Ashwell,Patrick Brassil,J. Breed,Juliet Ngozi O. Oka,Chun Deng,Michael Grondine,Candice L. Horn,Marine Souto Alves,Paul D. Lyne,Nicholas J. Newcombe,Martin Pass,Jon Read,Mei Su,Dorin Toader,Dingwei Yu,Yan Yu,Sonya Zabludoff	2012	19
8	SAR and inhibitor complex structure determination of a novel class of potent and specific Aurora kinase inhibitors Bioorganic & Medicinal Chemistry Letters ·Nicola M. Heron,Malcolm Anderson,David P. Blowers,J. Breed,Jonathan Eden,Stephen Green,George B. Hill,Trevor Johnson,Frédéric Jung,Helen McMiken,Andrew Mortlock,Andrew Pannifer,Richard A. Pauptit,Jennifer H. Pink,Nicola Roberts,Siân Rowsell	2005	101
9	Structure-based design of protein tyrosine phosphatase-1B inhibitors Bioorganic & Medicinal Chemistry Letters ·Emma Black,J. Breed,Alexander L. Breeze,Kevin J. Embrey,Robert Garcia,Thomas W. Gero,Bismark Kofi Meisuh,Peter W. Kenny,Andrew Morley,Claire A. Minshull,Andrew Pannifer,Jon Read,Amanda Rees,Daniel Russell,Dorin Toader,Julie A. Tucker	2005	60
10	Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase Bioorganic & Medicinal Chemistry Letters ·John G. Cumming,Rodas Gil,Stuart Bowden,Douglas S. Campbell,光文真弓,J. Breed,Philip J. Jewsbury	2004	54
11	Structure and Interactions of NCAM Ig1-2-3 Suggest a Novel Zipper Mechanism for Homophilic Adhesion Structure ·Vladislav Soroka,Kateryna Kolkova,J.S. Kastrup,Kay Diederichs,J. Breed,Vladislav V. Kiselyov,Flemming M. Poulsen,Ingrid Kjøller Larsen,Wolfram Welte,Vladimir Berezin,Elisabeth Bock,Christina Kasper	2003	145
12	An internal affinity‐tag for purification and crystallization of the siderophore receptor fhua, integral outer membrane protein from escherichia coli K‐12 Protein Science ·Andrew D. Ferguson,James W. Coulton,J. Breed,Kay Diederichs,Wolfram Welte	1998	40
13	A novel method for structure-based prediction of ion channel conductance properties Biophysical Journal ·Oliver S. Smart,J. Breed,Graham R. Smith,Mark S.P. Sansom	1997	183
14	The structure of porin from Paracoccus denitrificans at 3.1 Å resolution FEBS Letters ·Andreas Hirsch,J. Breed,Krishna Saxena,Mabel Teresa Chaos Vera,Bernd Ludwig,Kay Diederichs,Wolfram Welte	1997	48
15	Alamethicin channels – modelling via restrained molecular dynamics simulations Biochimica et Biophysica Acta (BBA) - Biomembranes ·J. Breed,Philip C. Biggin,Ian D. Kerr,Oliver S. Smart,Mark S.P. Sansom	1997	42
16	Polarity-dependent conformational switching of a peptide mimicking the S4–S5 linker of the voltage-sensitive sodium channel Biochimica et Biophysica Acta (BBA) - Biomembranes ·平野康一,J. Breed,Hervé Duclohier	1996	11
17	Water in channel-like cavities: structure and dynamics Biophysical Journal ·Mark S.P. Sansom,Ian D. Kerr,J. Breed,Ramasubbu Sankararamakrishnan	1996	121
18	Molecular modelling of Staphylococcal δ-toxin ion channels by restrained molecular dynamics Protein Engineering Design and Selection ·Ian D. Kerr,А. Е. Древаль,Ramasubbu Sankararamakrishnan,J. Breed,Mark S.P. Sansom	1996	23
19	Packing interactions of aib‐containing helices: Molecular modeling of parallel dimers of simple hydrophobic helices and of alamethicin Biopolymers ·J. Breed,Ian D. Kerr,Ramasubbu Sankararamakrishnan,Mark S.P. Sansom	1995	19
20	Conservation analysis and structure prediction of the SH2 family of phosphotyrosine binding domains FEBS Letters ·Robert B. Russell,J. Breed,Geoffrey J. Barton	1992	82

About J. Breed

J. Breed is a scholar working on Structural Biology, Molecular Biology and Cell Biology, having authored 51 papers that have together received 3.4k indexed citations. Recurring topics across this work include Lipid Membrane Structure and Behavior (6 papers), Enzyme Structure and Function (5 papers), Chemical Synthesis and Analysis (5 papers), Protein Structure and Dynamics (4 papers), Biochemical and Molecular Research (4 papers), Microtubule and mitosis dynamics (4 papers), Mass Spectrometry Techniques and Applications (4 papers) and Cancer-related Molecular Pathways (4 papers). The work is most often cited by research in Molecular Biology (2.4k citations), Immunology and Allergy (145 citations) and Oncology (582 citations). J. Breed has collaborated with scholars based in United Kingdom, Germany and United States. Frequent co-authors include Mark S.P. Sansom, Ian D. Kerr, Ramasubbu Sankararamakrishnan, Richard A. Norman, Wolfram Welte, Oliver S. Smart, Kay Diederichs, Graham R. Smith, Michael Gordon and Daniel C. Adelman. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Biophysical Journal, Journal of Medicinal Chemistry, Biochemistry and Structure.

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