S. Stokes

534 citations

18 papers · 436 indexed · h-index 12

Impact in

Molecular Medicine top 5%
- Antibiotic Resistance in Bacteria
Infectious Diseases top 10%
- Tuberculosis Research and Epidemiology

Papers in ⓘ

Molecular Biology 12
- Cancer therapeutics and mechanisms 8
- Biochemical and Molecular Research 6
- Chemical Synthesis and Analysis 2
Infectious Diseases 10
- Tuberculosis Research and Epidemiology 7

Co-authors: Adam B. Shapiro (4 shared papers)Ed T. Buurman (3 shared papers)Beth Andrews (3 shared papers)Ludovic R. Otterbein (3 shared papers)Robert Albert (4 shared papers)Michael J. Pucci (4 shared papers)Andrew R. McKenzie (2 shared papers)Ning Gao (3 shared papers)
Journals: Bioorganic & Medicinal Chemistry Letters (5 papers)Open Forum Infectious Diseases (3 papers)Antimicrobial Agents and Chemotherapy (2 papers)Journal of the American Chemical Society (1 paper)Journal of Biological Chemistry (1 paper)
Partner nations: United States United Kingdom Brazil

In The Last Decade

S. Stokes

17 papers receiving 417 citations

Peers

Countries citing papers authored by S. Stokes

Since Specialization

Citations

This map shows the geographic impact of S. Stokes's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by S. Stokes with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites S. Stokes more than expected).

Fields of papers citing papers by S. Stokes

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by S. Stokes. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by S. Stokes. The network helps show where S. Stokes may publish in the future.

Co-authors

The 25 scholars most cited alongside S. Stokes, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with S. Stokes Line = papers co-authored together S. Stokes links everyone, so they are left out of the graph.

All Works

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18 of 18 papers shown

#	Work
1	Inhibitors of the acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridylyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 2: Optimization of physical properties leading to antibacterial aryl sulfonamides Bioorganic & Medicinal Chemistry Letters ·S. Stokes, Robert Albert, Ed T. Buurman, Beth Andrews, Adam B. Shapiro, Oluyinka M. Green, Andrew R. McKenzie, Ludovic R. Otterbein	2012	77
2	Novel Bacterial NAD ⁺ -Dependent DNA Ligase Inhibitors with Broad-Spectrum Activity and Antibacterial Efficacy In Vivo Antimicrobial Agents and Chemotherapy ·Scott D. Mills, Ann E. Eakin, Ed T. Buurman, Joseph Newman, Ning Gao, Hoan K. Huynh, Kenneth D. Johnson, Sushmita D. Lahiri, Adam B. Shapiro, Grant K. Walkup, Wei Yang, S. Stokes	2010	63
3	In Vitro Validation of Acetyltransferase Activity of GlmU as an Antibacterial Target in Haemophilus influenzae Journal of Biological Chemistry ·Ed T. Buurman, Beth Andrews, Ning Gao, Jun Hu, Thomas A. Keating, Sushmita D. Lahiri, Ludovic R. Otterbein, Arthur D. Patten, S. Stokes, Adam B. Shapiro	2011	39
4	First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of SPR720, a Novel Oral Bacterial DNA Gyrase (GyrB) Inhibitor for Mycobacterial Infections Antimicrobial Agents and Chemotherapy ·Angela K. Talley, Archie Thurston, Grayson Moore, Vipul K. Gupta, Myriah M Satterfield, Erika Manyak, S. Stokes, Aaron Dane, David Melnick	2021	39
5	Advancement of GyrB Inhibitors for Treatment of Infections Caused by Mycobacterium tuberculosis and Non-tuberculous Mycobacteria ACS Infectious Diseases ·S. Stokes, Rajender Vemula, Michael J. Pucci	2020	28
6	Discovery of bacterial NAD+-dependent DNA ligase inhibitors: Optimization of antibacterial activity Bioorganic & Medicinal Chemistry Letters ·S. Stokes, Hoan K. Huynh, Madhusudhan Gowravaram, Robert Albert, Marta Cavero-Tomas, Brendan Chen, Jenna Harang, James T. Loch, Min Lu, G. B. MULLEN, Shannon X. Zhao, Ce-Feng Liu, Scott D. Mills	2011	26
7	New Approach to Bicyclo [5.3.0] Ring Systems Journal of the American Chemical Society ·Holly L. Deak, S. Stokes, Marc L. Snapper	2001	25
8	Inhibitors of acetyltransferase domain of N-acetylglucosamine-1-phosphate-uridyltransferase/glucosamine-1-phosphate-acetyltransferase (GlmU). Part 1: Hit to lead evaluation of a novel arylsulfonamide series Bioorganic & Medicinal Chemistry Letters ·Oluyinka M. Green, Andrew R. McKenzie, Adam B. Shapiro, Ludovic R. Otterbein, Haihong Ni, Arthur D. Patten, S. Stokes, Robert Albert, Sameer Kawatkar, J. Breed	2012	24
9	Novel topoisomerase inhibitors: microbiological characterisation and in vivo efficacy of pyrimidines International Journal of Antimicrobial Agents ·Maria Uria-Nickelsen, Georg Neckermann, Shubha Sriram, Beth Andrews, John I. Manchester, D. Carcanague, S. Stokes, Kenneth G. Hull	2013	24
10	Methods to Circumvent a Difficult Coupling in the Solid-Phase Synthesis of Cyclosporine Analogues The Journal of Organic Chemistry ·Prakash Raman, S. Stokes, Yvonne M. Angell, George R. Flentke, Daniel H. Rich	1998	20
11	Discovery of bacterial NAD+-dependent DNA ligase inhibitors: Improvements in clearance of adenosine series Bioorganic & Medicinal Chemistry Letters ·S. Stokes, Madhusudhan Gowravaram, Hoan K. Huynh, Min Lu, G. B. MULLEN, Brendan Chen, Robert Albert, Thomas J. O’Shea, Michael Rooney, Haiqing Hu, Joseph Newman, Scott D. Mills	2011	19
12	In Vitro Resistance against DNA Gyrase Inhibitor SPR719 in Mycobacterium avium and Mycobacterium abscessus Microbiology Spectrum ·Wassihun Wedajo Aragaw, Nicole Cotroneo, S. Stokes, Michael J. Pucci, Ian A. Critchley, Martin Gengenbacher, Thomas Dick	2022	18
13	Identification through structure-based methods of a bacterial NAD+-dependent DNA ligase inhibitor that avoids known resistance mutations Bioorganic & Medicinal Chemistry Letters ·Kerry E. Murphy-Benenato, Hongming Wang, Helen M. McGuire, Hajnalka E. Davis, Ning Gao, D. Bryan Prince, Haris Jahić, S. Stokes, P. Ann Boriack‐Sjodin	2013	10
14	Efficacy of SPR720 in murine models of non-tuberculous mycobacterial pulmonary infection Journal of Antimicrobial Chemotherapy ·Nicole Cotroneo, S. Stokes, Michael J. Pucci, Aileen Rubio, Kamal Hamed, Ian A Critchley	2024	9
15	New Antibacterial Agents: Patent Applications Published in 2010 Pharmaceutical Patent Analyst ·S. Stokes, Marshall Morningstar, Helena Kocis, Jeroen C. Verheijen	2012	5
16	1659. Pharmacokinetics/pharmacodynamics of the Novel Gyrase Inhibitor SPR719/SPR720 and Clinical Dose Selection to Treat Pulmonary Mycobacterium avium-complex Disease Open Forum Infectious Diseases ·Devyani Deshpande, Daniel Kuret, Kayle Cirrincione, Nicole Cotroneo, David Melnick, Troy Lister, S. Stokes, Tawanda Gumbo	2020	5
17	1637. SPR720, A Novel Benzamidazole Gyrase Inhibitor, Demonstrates Potent Efficacy Against Mycobacterium avium ATCC 700898 in a Chronic C3HeBFeJ Mouse Infection Model Open Forum Infectious Diseases ·Deepshikha Verma, Chelsea Peterson, Nicole Cotroneo, S. Stokes, Diane Ordway	2020	4
18	1274. Evaluating the Activity of SPR719, a Novel Aminobenzimidazole, against Nontuberculous Mycobacteria Open Forum Infectious Diseases ·Beverly Murray, Danielle Hall, Nicole Cotroneo, Ian A. Critchley, Michael J. Pucci, S. Stokes, Chris M. Pillar	2020	1

About S. Stokes

S. Stokes is a scholar working on Molecular Biology, Infectious Diseases, Epidemiology, Molecular Medicine and Organic Chemistry, having authored 18 papers that have together received 436 indexed citations. Recurring topics across this work include Cancer therapeutics and mechanisms (8 papers), Tuberculosis Research and Epidemiology (7 papers), Mycobacterium research and diagnosis (7 papers), Biochemical and Molecular Research (6 papers), Antibiotic Resistance in Bacteria (4 papers), Infectious Diseases and Mycology (3 papers), Chemical Synthesis and Analysis (2 papers) and Metabolism and Genetic Disorders (1 paper). The work is most often cited by research in Molecular Medicine (82 citations), Infectious Diseases (133 citations), Toxicology (20 citations), Organic Chemistry (163 citations) and Molecular Biology (284 citations). S. Stokes has collaborated with scholars based in United States, United Kingdom and Brazil. Frequent co-authors include Adam B. Shapiro, Ed T. Buurman, Beth Andrews, Ludovic R. Otterbein, Robert Albert, Michael J. Pucci, Andrew R. McKenzie, Ning Gao, Hoan K. Huynh and Scott D. Mills. Their work appears in journals such as Bioorganic & Medicinal Chemistry Letters, Open Forum Infectious Diseases, Antimicrobial Agents and Chemotherapy, Journal of the American Chemical Society and Journal of Biological Chemistry.

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