Anthony D. Keefe

7.0k total citations · 3 hit papers
41 papers, 5.0k citations indexed

About

Anthony D. Keefe is a scholar working on Molecular Biology, Organic Chemistry and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Anthony D. Keefe has authored 41 papers receiving a total of 5.0k indexed citations (citations by other indexed papers that have themselves been cited), including 28 papers in Molecular Biology, 13 papers in Organic Chemistry and 8 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Anthony D. Keefe's work include Advanced biosensing and bioanalysis techniques (12 papers), Chemical Synthesis and Analysis (9 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Anthony D. Keefe is often cited by papers focused on Advanced biosensing and bioanalysis techniques (12 papers), Chemical Synthesis and Analysis (9 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Anthony D. Keefe collaborates with scholars based in United States, United Kingdom and Switzerland. Anthony D. Keefe's co-authors include Andrew D. Ellington, Supriya Pai, Jack W. Szostak, David Sloan Wilson, Christoph E. Dumelin, Robert A. Goodnow, Sharon T. Cload, Stanley L. Miller, Claire Wilson and Burckhard Seelig and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Journal of Molecular Biology.

In The Last Decade

Anthony D. Keefe

41 papers receiving 4.8k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Aptamers as therapeutics

2010 1.8k citations Anthony D. Keefe, Supriya Pai et al. Nature Reviews Drug Discovery profile →
DNA-encoded chemistry: enabling the deeper sampling of chemical space

2016 459 citations Robert A. Goodnow, Christoph E. Dumelin et al. Nature Reviews Drug Discovery profile →
Functional proteins from a random-sequence library

2001 400 citations Anthony D. Keefe, Jack W. Szostak Nature profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Anthony D. Keefe United States	25	4.3k	814	761	691	272	41	5.0k
Matthew Levy United States	32	3.8k 0.9×	299 0.4×	811 1.1×	357 0.5×	398 1.5×	70	4.6k
Valentina Tereshko United States	39	3.6k 0.9×	346 0.4×	377 0.5×	394 0.6×	546 2.0×	58	4.4k
Ansgar Brock United States	30	3.1k 0.7×	643 0.8×	176 0.2×	849 1.2×	278 1.0×	51	4.0k
Ichiro Hirao Japan	43	4.8k 1.1×	131 0.2×	325 0.4×	1.4k 2.0×	258 0.9×	215	6.0k
Beate Koksch Germany	39	3.9k 0.9×	393 0.5×	358 0.5×	2.4k 3.5×	664 2.4×	178	6.2k
Tom N. Grossmann Germany	36	4.4k 1.0×	532 0.7×	177 0.2×	1.6k 2.3×	267 1.0×	90	5.1k
Chang C. Liu United States	23	2.7k 0.6×	453 0.6×	173 0.2×	662 1.0×	156 0.6×	49	3.2k
F.R. Salemme United States	29	3.7k 0.9×	430 0.5×	327 0.4×	604 0.9×	1.2k 4.5×	57	5.3k
Stephen J. Benkovic United States	33	3.2k 0.8×	1.1k 1.4×	135 0.2×	477 0.7×	789 2.9×	83	4.4k
Frank Seela Germany	46	7.9k 1.9×	255 0.3×	161 0.2×	3.3k 4.7×	437 1.6×	577	9.5k

Countries citing papers authored by Anthony D. Keefe

Since Specialization

Citations

This map shows the geographic impact of Anthony D. Keefe's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Anthony D. Keefe with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Anthony D. Keefe more than expected).

Fields of papers citing papers by Anthony D. Keefe

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Anthony D. Keefe. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Anthony D. Keefe. The network helps show where Anthony D. Keefe may publish in the future.

Co-authorship network of co-authors of Anthony D. Keefe

This figure shows the co-authorship network connecting the top 25 collaborators of Anthony D. Keefe. A scholar is included among the top collaborators of Anthony D. Keefe based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Anthony D. Keefe. Anthony D. Keefe is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

Collie, Gavin W., Matthew Clark, Anthony D. Keefe, et al.. (2024). Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein–Ligand Interactions and High Selectivity. Journal of Medicinal Chemistry. 67(2). 864–884. 15 indexed citations

Litovchick, Alexander & Anthony D. Keefe. (2022). Chemical Ligation of Oligonucleotide Tags to Support Encoded Chemical Library Synthesis. Methods in molecular biology. 2541. 25–32. 1 indexed citations

Litovchick, Alexander, Tian Xia, Marie-Aude Guié, et al.. (2019). Novel Nucleic Acid Binding Small Molecules Discovered Using DNA-Encoded Chemistry. Molecules. 24(10). 2026–2026. 26 indexed citations

Cuozzo, John W., Diana Gikunju, Sevan Habeshian, et al.. (2017). Discovery of a Potent BTK Inhibitor with a Novel Binding Mode by Using Parallel Selections with a DNA‐Encoded Chemical Library. ChemBioChem. 18(9). 864–871. 51 indexed citations

Soutter, Holly H., Matthew Clark, John W. Cuozzo, et al.. (2016). Discovery of cofactor-specific, bactericidal Mycobacterium tuberculosis InhA inhibitors using DNA-encoded library technology. Proceedings of the National Academy of Sciences. 113(49). E7880–E7889. 46 indexed citations

Goodnow, Robert A., Christoph E. Dumelin, & Anthony D. Keefe. (2016). DNA-encoded chemistry: enabling the deeper sampling of chemical space. Nature Reviews Drug Discovery. 16(2). 131–147. 459 indexed citations breakdown →

Litovchick, Alexander, Christoph E. Dumelin, Sevan Habeshian, et al.. (2015). Encoded Library Synthesis Using Chemical Ligation and the Discovery of sEH Inhibitors from a 334-Million Member Library. Scientific Reports. 5(1). 10916–10916. 87 indexed citations

Litovchick, Alexander, Matthew Clark, & Anthony D. Keefe. (2014). Universal strategies for the DNA-encoding of libraries of small molecules using the chemical ligation of oligonucleotide tags. PubMed. 5(1). e27896–e27896. 23 indexed citations

Keefe, Anthony D., Supriya Pai, & Andrew D. Ellington. (2010). Aptamers as therapeutics. Nature Reviews Drug Discovery. 9(7). 537–550. 1785 indexed citations breakdown →

10.

Wang, Chunhua, Kristin Thompson, P. Shannon Pendergrast, et al.. (2006). 2´-Deoxy Purine, 2´-O-Methyl Pyrimidine (dRmY) Aptamers as Candidate Therapeutics. Oligonucleotides. 16(4). 337–351. 49 indexed citations

11.

Wilson, Claire & Anthony D. Keefe. (2006). Building oligonucleotide therapeutics using non-natural chemistries. Current Opinion in Chemical Biology. 10(6). 607–614. 143 indexed citations

12.

Pendergrast, P. Shannon, Thomas McCauley, Jeffrey C. Kurz, et al.. (2005). Direct In Vitro Selection of a 2′-O-Methyl Aptamer to VEGF. Chemistry & Biology. 12(1). 25–33. 272 indexed citations

13.

Wilson, David Sloan, Anthony D. Keefe, & Jack W. Szostak. (2001). The use of mRNA display to select high-affinity protein-binding peptides. Proceedings of the National Academy of Sciences. 98(7). 3750–3755. 315 indexed citations

14.

Keefe, Anthony D., David Sloan Wilson, Burckhard Seelig, & Jack W. Szostak. (2001). One-Step Purification of Recombinant Proteins Using a Nanomolar-Affinity Streptavidin-Binding Peptide, the SBP-Tag. Protein Expression and Purification. 23(3). 440–446. 211 indexed citations

15.

Keefe, Anthony D. & Jack W. Szostak. (2001). Functional proteins from a random-sequence library. Nature. 410(6829). 715–718. 400 indexed citations breakdown →

16.

Wilson, David Sloan & Anthony D. Keefe. (2000). Random Mutagenesis by PCR. Current Protocols in Molecular Biology. 51(1). Unit8.3–Unit8.3. 81 indexed citations

17.

Keefe, Anthony D., et al.. (2000). Constructing high complexity synthetic libraries of long ORFs using In Vitro selection. Journal of Molecular Biology. 297(2). 309–319. 95 indexed citations

18.

Keefe, Anthony D. & Stanley L. Miller. (1996). Potentially prebiotic syntheses of condensed phosphates. Origins of Life and Evolution of Biospheres. 26(1). 15–25. 24 indexed citations

19.

Keefe, Anthony D., Antonio Lazcano, & Stanley L. Miller. (1995). Evolution of the biosynthesis of the branched-chain amino acids. Origins of Life and Evolution of Biospheres. 25(1-3). 99–110. 11 indexed citations

20.

Keefe, Anthony D., Gerald L. Newton, & Stanley L. Miller. (1995). A possible prebiotic synthesis of pantetheine, a precursor to coenzyme A. Nature. 373(6516). 683–685. 93 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact