Hyunbum Jang

10.5k total citations · 2 hit papers
192 papers, 7.7k citations indexed

About

Hyunbum Jang is a scholar working on Molecular Biology, Physiology and Cell Biology. According to data from OpenAlex, Hyunbum Jang has authored 192 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 163 papers in Molecular Biology, 30 papers in Physiology and 28 papers in Cell Biology. Recurrent topics in Hyunbum Jang's work include Protein Kinase Regulation and GTPase Signaling (68 papers), Protein Structure and Dynamics (28 papers) and PI3K/AKT/mTOR signaling in cancer (27 papers). Hyunbum Jang is often cited by papers focused on Protein Kinase Regulation and GTPase Signaling (68 papers), Protein Structure and Dynamics (28 papers) and PI3K/AKT/mTOR signaling in cancer (27 papers). Hyunbum Jang collaborates with scholars based in United States, Israel and Türkiye. Hyunbum Jang's co-authors include Ruth Nussinov, Chung‐Jung Tsai, Mingzhen Zhang, Ratnesh Lal, Fernando Terán Arce, Srinivasan Ramachandran, Jian Zhang, Shaoyong Lu, Jie Zheng and Ricardo Capone and has published in prestigious journals such as Chemical Reviews, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

In The Last Decade

Hyunbum Jang

188 papers receiving 7.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Anticancer drug resistance: An update and perspective

2021 272 citations Ruth Nussinov, Chung‐Jung Tsai et al. profile →
Molecular principles underlying aggressive cancers

2025 17 citations Ruth Nussinov, Hyunbum Jang et al. Signal Transduction and Targeted Therapy profile →

Peers

Hyunbum Jang

MB

PHYSI

CTM

ONCOL

CB

Evan T. Powers United States

Torleif Härd Sweden

Chung‐Jung Tsai United States

Aleksey Lomakin United States

Andrew D. Miranker United States

Per Hammarström Sweden

Edward T. Olejniczak United States

Charles R. Sanders United States

John E. Harlan United States

Gianluigi Veglia United States

Evan T. Powers United States

Hyunbum Jang

7.2k ×1.2

MB

2.5k ×1.4

PHYSI

358 ×0.4

CTM

902 ×1.1

ONCOL

2.1k ×2.7

CB

Citations per year, relative to Hyunbum Jang Hyunbum Jang (= 1×) peers Evan T. Powers

Countries citing papers authored by Hyunbum Jang

Since Specialization

Citations

This map shows the geographic impact of Hyunbum Jang's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hyunbum Jang with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hyunbum Jang more than expected).

Fields of papers citing papers by Hyunbum Jang

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hyunbum Jang. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hyunbum Jang. The network helps show where Hyunbum Jang may publish in the future.

Co-authorship network of co-authors of Hyunbum Jang

This figure shows the co-authorship network connecting the top 25 collaborators of Hyunbum Jang. A scholar is included among the top collaborators of Hyunbum Jang based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hyunbum Jang. Hyunbum Jang is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

1.

Nussinov, Ruth, et al.. (2025). Allostery in Disease: Anticancer Drugs, Pockets, and the Tumor Heterogeneity Challenge. Journal of Molecular Biology. 437(20). 169050–169050. 4 indexed citations

2.

Xu, Liang, Yonglan Liu, Hyunbum Jang, & Ruth Nussinov. (2025). M-Ras distinct activation scenarios: A mechanistic outlook and targeting. Computational and Structural Biotechnology Journal. 27. 5207–5219.

3.

Xu, Liang, Hyunbum Jang, & Ruth Nussinov. (2025). Allosteric modulation of NF1 GAP: Differential distributions of catalytically competent populations in loss‐of‐function and gain‐of‐function mutants. Protein Science. 34(2). e70042–e70042. 5 indexed citations

4.

Nussinov, Ruth & Hyunbum Jang. (2025). How residence time works in allosteric drugs. Current Opinion in Structural Biology. 94. 103149–103149. 1 indexed citations

5.

Nussinov, Ruth, et al.. (2025). Molecular principles underlying aggressive cancers. Signal Transduction and Targeted Therapy. 10(1). 42–42. 17 indexed citations breakdown →

6.

Ramelot, Theresa A., Attila Gürsoy, Hyunbum Jang, et al.. (2024). Tumor-derived RHOA mutants interact with effectors in the GDP-bound state. Nature Communications. 15(1). 7176–7176. 5 indexed citations

7.

Steklov, Mikhail, Hyunbum Jang, Raj Nayan Sewduth, et al.. (2024). K128 ubiquitination constrains RAS activity by expanding its binding interface with GAP proteins. The EMBO Journal. 43(14). 2862–2877. 8 indexed citations

8.

Nussinov, Ruth, Hyunbum Jang, & Feixiong Cheng. (2024). Ras, RhoA, and vascular pharmacology in neurodevelopment and aging. Neurochemistry International. 181. 105883–105883. 1 indexed citations

9.

Zhang, Wengang, Yonglan Liu, Hyunbum Jang, & Ruth Nussinov. (2024). Slower CDK4 and faster CDK2 activation in the cell cycle. Structure. 32(8). 1269–1280.e2. 11 indexed citations

10.

Haspel, Nurit, Hyunbum Jang, & Ruth Nussinov. (2024). Allosteric Activation of RhoA Complexed with p115-RhoGEF Deciphered by Conformational Dynamics. Journal of Chemical Information and Modeling. 64(3). 862–873. 5 indexed citations

11.

Jang, Hyunbum, et al.. (2023). Molecular mechanism of regulation of RhoA GTPase by phosphorylation of RhoGDI. Biophysical Journal. 123(1). 57–67. 6 indexed citations

12.

Nussinov, Ruth, Mingzhen Zhang, Yonglan Liu, et al.. (2023). Neurodevelopmental disorders, like cancer, are connected to impaired chromatin remodelers, PI3K/mTOR, and PAK1-regulated MAPK. Biophysical Reviews. 15(2). 163–181. 31 indexed citations

13.

Nussinov, Ruth, Chung‐Jung Tsai, & Hyunbum Jang. (2022). Allostery, and how to define and measure signal transduction. Biophysical Chemistry. 283. 106766–106766. 35 indexed citations

14.

Nussinov, Ruth, et al.. (2022). Allostery: Allosteric Cancer Drivers and Innovative Allosteric Drugs. Journal of Molecular Biology. 434(17). 167569–167569. 48 indexed citations

15.

Haspel, Nurit, Hyunbum Jang, & Ruth Nussinov. (2020). Active and Inactive Cdc42 Differ in Their Insert Region Conformational Dynamics. Biophysical Journal. 120(2). 306–318. 18 indexed citations

16.

Muratcioğlu, Serena, Cihan Aydın, Elif Nur Firat‐Karalar, et al.. (2020). Oncogenic K-Ras4B Dimerization Enhances Downstream Mitogen-activated Protein Kinase Signaling. Journal of Molecular Biology. 432(4). 1199–1215. 14 indexed citations

17.

Zhang, Mingzhen, Hyunbum Jang, Shaoyong Lu, et al.. (2018). Interaction of Calmodulin with the cSH2 Domain of the p85 Regulatory Subunit. Biochemistry. 57(12). 1917–1928. 10 indexed citations

18.

Zhang, Mingzhen, Zhigang Li, Hyunbum Jang, et al.. (2018). Calmodulin (CaM) Activates PI3Kα by Targeting the “Soft” CaM-Binding Motifs in Both the nSH2 and cSH2 Domains of p85α. The Journal of Physical Chemistry B. 122(49). 11137–11146. 16 indexed citations

19.

Lee, Joon, Young Hun Kim, Fernando Terán Arce, et al.. (2017). Amyloid β Ion Channels in a Membrane Comprising Brain Total Lipid Extracts. ACS Chemical Neuroscience. 8(6). 1348–1357. 63 indexed citations

20.

Jang, Hyunbum, et al.. (2014). Activity and Architecture of Pyroglutamate-Modified Amyloid-β (AβpE3-42) Pores. The Journal of Physical Chemistry. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact