Tanja Kortemme

28.1k total citations · 7 hit papers
100 papers, 11.0k citations indexed

About

Tanja Kortemme is a scholar working on Molecular Biology, Materials Chemistry and Computational Theory and Mathematics. According to data from OpenAlex, Tanja Kortemme has authored 100 papers receiving a total of 11.0k indexed citations (citations by other indexed papers that have themselves been cited), including 92 papers in Molecular Biology, 37 papers in Materials Chemistry and 9 papers in Computational Theory and Mathematics. Recurrent topics in Tanja Kortemme's work include Protein Structure and Dynamics (65 papers), Enzyme Structure and Function (35 papers) and RNA and protein synthesis mechanisms (34 papers). Tanja Kortemme is often cited by papers focused on Protein Structure and Dynamics (65 papers), Enzyme Structure and Function (35 papers) and RNA and protein synthesis mechanisms (34 papers). Tanja Kortemme collaborates with scholars based in United States, Germany and Canada. Tanja Kortemme's co-authors include David Baker, Alexandre V. Morozov, Colin A. Smith, Avijit Chakrabartty, Robert L. Baldwin, Thomas E. Creighton, David E. Kim, Daniel J. Mandell, Marina Ramı́rez-Alvarado and Brian Kuhlman and has published in prestigious journals such as Nature, Science and Cell.

In The Last Decade

Tanja Kortemme

100 papers receiving 10.9k citations

Hit Papers

5 papers align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design

2017 942 citations Rebecca F. Alford, Andrew Leaver‐Fay et al. Journal of Chemical Theory and Computation profile →
A simple physical model for binding energy hot spots in protein–protein complexes

2002 653 citations Tanja Kortemme, David Baker Proceedings of the National Academy of Sciences profile →
Helix propensities of the amino acids measured in alanine‐based peptides without helix‐stabilizing side‐chain interactions

1994 545 citations Tanja Kortemme et al. profile →
Computational Alanine Scanning of Protein-Protein Interfaces

2004 460 citations Tanja Kortemme, David Baker et al. profile →
An Orientation-dependent Hydrogen Bonding Potential Improves Prediction of Specificity and Structure for Proteins and Protein–Protein Complexes

2003 417 citations Tanja Kortemme, David Baker et al. profile →
Ca2+ Indicators Based on Computationally Redesigned Calmodulin-Peptide Pairs

2006 405 citations Tanja Kortemme, David Baker et al. profile →
De novo protein design—From new structures to programmable functions

2024 117 citations Tanja Kortemme profile →

Peers

Countries citing papers authored by Tanja Kortemme

Since Specialization

Citations

This map shows the geographic impact of Tanja Kortemme's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Tanja Kortemme with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Tanja Kortemme more than expected).

Fields of papers citing papers by Tanja Kortemme

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Tanja Kortemme. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Tanja Kortemme. The network helps show where Tanja Kortemme may publish in the future.

Co-authorship network of co-authors of Tanja Kortemme

This figure shows the co-authorship network connecting the top 25 collaborators of Tanja Kortemme. A scholar is included among the top collaborators of Tanja Kortemme based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Tanja Kortemme. Tanja Kortemme is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Deep learning–guided design of dynamic proteins 2025 ·Science ·(unknown), (unknown), (unknown), Michael Grabe, Colin A. Smith, Mark J. S. Kelly, Tanja Kortemme	10
2	Ligand-specific changes in conformational flexibility mediate long-range allostery in the lac repressor 2023 ·Nature Communications ·Anum Glasgow, (unknown), (unknown), (unknown), Susan Marqusee, Tanja Kortemme	20
3	Emerging maps of allosteric regulation in cellular networks 2023 ·Current Opinion in Structural Biology ·Christopher J.P. Mathy, Tanja Kortemme	11
4	Advances in the Computational Design of Small-Molecule-Controlled Protein-Based Circuits for Synthetic Biology 2022 ·Proceedings of the IEEE ·Simon Kretschmer, Tanja Kortemme	2
5	Accurate positioning of functional residues with robotics-inspired computational protein design 2022 ·Proceedings of the National Academy of Sciences ·(unknown), (unknown), Xingjie Pan, Roland A. Pache, Lin Liu, Shane Ó Conchúir, Jeliazko R. Jeliazkov, Jeffrey J. Gray, Michael C. Thompson, James S. Fraser, Tanja Kortemme	6
6	De novo protein fold families expand the designable ligand binding site space 2021 ·PLoS Computational Biology ·Xingjie Pan, Tanja Kortemme	3
7	Design principles of protein switches 2021 ·Current Opinion in Structural Biology ·Robert G. Alberstein, (unknown), Tanja Kortemme	28
8	Systems-level effects of allosteric perturbations to a model molecular switch 2021 ·Nature ·Tina Perica, Christopher J.P. Mathy, Jiewei Xu, Gwendolyn Μ. Jang, (unknown), Robyn M. Kaake, Noah Ollikainen, Hannes Braberg, Danielle L. Swaney, David G. Lambright, Mark J. S. Kelly, Nevan J. Krogan, Tanja Kortemme	12
9	Expanding the space of protein geometries by computational design of de novo fold families 2020 ·Science ·Xingjie Pan, Michael C. Thompson, Sunny Zhang, Lin Liu, James S. Fraser, Mark J. S. Kelly, Tanja Kortemme	58
10	New computational protein design methods for de novo small molecule binding sites 2020 ·PLoS Computational Biology ·James E. Lucas, Tanja Kortemme	21
11	Engineered ACE2 receptor traps potently neutralize SARS-CoV-2 2020 ·Proceedings of the National Academy of Sciences ·Anum Glasgow, Jeff E. Glasgow, Daniel Limonta, Paige Solomon, Irene Lui, Sunny Zhang, Matthew A. Nix, Nicholas J. Rettko, Beth Shoshana Zha, Rachel Yamin, Kevin S. Kao, Oren S. Rosenberg, Jeffrey V. Ravetch, Arun P. Wiita, Kevin Leung, Shion A. Lim, Xin Zhou, Tom C. Hobman, Tanja Kortemme, James A. Wells	160
12	Controlling CRISPR-Cas9 with ligand-activated and ligand-deactivated sgRNAs 2019 ·Nature Communications ·(unknown), James E. Lucas, Kyle E. Watters, Christof Fellmann, Andrew H. Ng, Benjamin M. Heineike, (unknown), Benjamin L. Oakes, Jiuxin Qu, Neha Prasad, Oren S. Rosenberg, David F. Savage, Hana El‐Samad, Jennifer A. Doudna, Tanja Kortemme	147
13	Comparison of Rosetta flexible‐backbone computational protein design methods on binding interactions 2019 ·Proteins Structure Function and Bioinformatics ·Amanda L. Loshbaugh, Tanja Kortemme	29
14	Computational design of a modular protein sense-response system 2019 ·Science ·Anum Glasgow, Yao-Ming Huang, Daniel J. Mandell, Michael C. Thompson, Ryan Ritterson, Amanda L. Loshbaugh, J. Pellegrino, (unknown), Roland A. Pache, Kyle A. Barlow, Noah Ollikainen, (unknown), Mark J. S. Kelly, James S. Fraser, Tanja Kortemme	92
15	Flex ddG: Rosetta Ensemble-Based Estimation of Changes in Protein–Protein Binding Affinity upon Mutation 2018 ·The Journal of Physical Chemistry B ·Kyle A. Barlow, Shane Ó Conchúir, Samuel Thompson, Pooja Suresh, James E. Lucas, Markus Heinonen, Tanja Kortemme	158
16	The Rosetta All-Atom Energy Function for Macromolecular Modeling and Design breakdown → 2017 ·Journal of Chemical Theory and Computation ·Rebecca F. Alford, Andrew Leaver‐Fay, Jeliazko R. Jeliazkov, Matthew J. O’Meara, Frank DiMaio, Hahnbeom Park, Maxim V. Shapovalov, P. Douglas Renfrew, Vikram Khipple Mulligan, Kalli Kappel, Jason W. Labonte, Michael S. Pacella, Richard Bonneau, Philip Bradley, Roland L. Dunbrack, Rhiju Das, David Baker, Brian Kuhlman, Tanja Kortemme, Jeffrey J. Gray	942
17	Deconstruction of the Ras switching cycle through saturation mutagenesis 2017 ·eLife ·Pradeep Bandaru, Neel H. Shah, Moitrayee Bhattacharyya, John P. Barton, Yasushi Kondo, Joshua C. Cofsky, Christine L. Gee, Arup K. Chakraborty, Tanja Kortemme, Rama Ranganathan, John Kuriyan	70
18	Cost-Benefit Tradeoffs in Engineered lac Operons 2012 ·Science ·(unknown), Tanja Kortemme	80
19	SAT-based protein design 2009 ·International Conference on Computer Aided Design ·Noah Ollikainen, Ellen Sentovich, (unknown), Andreas Kuehlmann, Tanja Kortemme	7
20	A Ras-induced conformational switch in the Ras activator Son of sevenless 2006 ·Proceedings of the National Academy of Sciences ·Tanya S. Freedman, Holger Sondermann, Gregory D. Friedland, Tanja Kortemme, Dafna Bar‐Sagi, Susan Marqusee, John Kuriyan	116

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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