Huan‐Chieh Chien

1.3k total citations
22 papers, 809 citations indexed

About

Huan‐Chieh Chien is a scholar working on Molecular Biology, Oncology and Biochemistry. According to data from OpenAlex, Huan‐Chieh Chien has authored 22 papers receiving a total of 809 indexed citations (citations by other indexed papers that have themselves been cited), including 10 papers in Molecular Biology, 8 papers in Oncology and 7 papers in Biochemistry. Recurrent topics in Huan‐Chieh Chien's work include Drug Transport and Resistance Mechanisms (8 papers), Amino Acid Enzymes and Metabolism (7 papers) and Metabolism and Genetic Disorders (4 papers). Huan‐Chieh Chien is often cited by papers focused on Drug Transport and Resistance Mechanisms (8 papers), Amino Acid Enzymes and Metabolism (7 papers) and Metabolism and Genetic Disorders (4 papers). Huan‐Chieh Chien collaborates with scholars based in United States, China and United Kingdom. Huan‐Chieh Chien's co-authors include Kathleen M. Giacomini, Sook Wah Yee, Eugene C. Chen, Xiaomin Liang, Arik A. Zur, Ling Zou, Adrian Stecuła, Youcai Zhang, Avner Schlessinger and Allen A. Thomas and has published in prestigious journals such as Science, Proceedings of the National Academy of Sciences and The FASEB Journal.

In The Last Decade

Huan‐Chieh Chien

21 papers receiving 804 citations

Peers

Countries citing papers authored by Huan‐Chieh Chien

Since Specialization

Citations

This map shows the geographic impact of Huan‐Chieh Chien's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Huan‐Chieh Chien with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Huan‐Chieh Chien more than expected).

Fields of papers citing papers by Huan‐Chieh Chien

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Huan‐Chieh Chien. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Huan‐Chieh Chien. The network helps show where Huan‐Chieh Chien may publish in the future.

Co-authorship network of co-authors of Huan‐Chieh Chien

This figure shows the co-authorship network connecting the top 25 collaborators of Huan‐Chieh Chien. A scholar is included among the top collaborators of Huan‐Chieh Chien based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Huan‐Chieh Chien. Huan‐Chieh Chien is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work	Indexed citations
1	Considerations in Kp,uu,brain-based Strategy for Selecting CNS-targeted Drug Candidates with Sufficient Target Coverage and Substantial Pharmacodynamic Effect 2025 ·The AAPS Journal ·Ling Zou, Huan‐Chieh Chien, (unknown), Yanfei Li, M. Hong Nguyen, Ravi Kanth Bhamidipati, (unknown), (unknown), Jan L. Wahlstrom	0
2	Transporter-mediated drug-drug interactions: regulatory guidelines, in vitro and in vivo methodologies and translation, special populations, and the blood-brain barrier 2024 ·Drug Metabolism Reviews ·Laura Russell, (unknown), (unknown), Huan‐Chieh Chien, Ling Zou, (unknown), (unknown)	1
3	Cardiac contraction and relaxation are regulated by distinct subcellular cAMP pools 2023 ·Nature Chemical Biology ·Ting‐Yu Lin, N. Quynh, (unknown), Emily B. Wilson, Huan‐Chieh Chien, Sook Wah Yee, Kathleen M. Giacomini, Jeffrey E. Olgin, Roshanak Irannejad	29
4	Transporters and Toxicity: Insights From the International Transporter Consortium Workshop 4 2022 ·Clinical Pharmacology & Therapeutics ·Michael J. Hafey, Lauren M. Aleksunes, Christy C. Bridges, Kenneth R. Brouwer, Huan‐Chieh Chien, Elaine M. Leslie, Shuiying Hu, Yang Li, (unknown), Alex Sparreboom, Jason A. Sprowl, Donald Tweedie, Yurong Lai	7
5	Bacterial metabolism rescues the inhibition of intestinal drug absorption by food and drug additives 2020 ·Proceedings of the National Academy of Sciences ·Ling Zou, Peter Spanogiannopoulos, Lindsey M. Pieper, Huan‐Chieh Chien, Wenlong Cai, Natalia Khuri, Joshua Pottel, Bianca Vora, Zhanglin Ni, Eleftheria Tsakalozou, Wenjun Zhang, Brian K. Shoichet, Kathleen M. Giacomini, Peter J. Turnbaugh	41
6	Deorphaning a solute carrier 22 family member, SLC22A15, through functional genomic studies 2020 ·The FASEB Journal ·Sook Wah Yee, (unknown), Adrian Stecuła, Huy Ngo, Huan‐Chieh Chien, Ling Zou, (unknown), Kathleen M. Giacomini	32
7	The Effects of Prodrug Size and a Carbonyl Linker on l‐Type Amino Acid Transporter 1‐Targeted Cellular and Brain Uptake 2020 ·ChemMedChem ·(unknown), (unknown), Huy Ngo, Huan‐Chieh Chien, (unknown), (unknown), (unknown), J. Griffith, (unknown), Surabhi Chandra, (unknown), Avner Schlessinger, Allen A. Thomas	6
8	Unraveling the functional role of the orphan solute carrier, SLC22A24 in the transport of steroid conjugates through metabolomic and genome-wide association studies 2019 ·PLoS Genetics ·Sook Wah Yee, Adrian Stecuła, Huan‐Chieh Chien, Ling Zou, Elena V. Feofanova, (unknown), (unknown), Noha A. Yousri, Karsten Suhre, Jason M. Kinchen, Eric Boerwinkle, Roshanak Irannejad, Bing Yu, Kathleen M. Giacomini	21
9	l-Type amino acid transporter 1 activity of 1,2,3-triazolyl analogs of l-histidine and l-tryptophan 2019 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), (unknown), (unknown), Huan‐Chieh Chien, Claire Colas, Avner Schlessinger, Kathleen M. Giacomini, Allen A. Thomas	17
10	Organic cation transporter 1 (OCT1) modulates multiple cardiometabolic traits through effects on hepatic thiamine content 2018 ·PLoS Biology ·Xiaomin Liang, Sook Wah Yee, Huan‐Chieh Chien, Eugene C. Chen, Qi Luo, Ling Zou, (unknown), (unknown), Ligong Chen, Meredith Calvert, Sarah King, Frode Norheim, (unknown), Ronald M. Krauss, Kathleen M. Giacomini	49
11	Molecular Mechanisms for Species Differences in Organic Anion Transporter 1, OAT1: Implications for Renal Drug Toxicity 2018 ·Molecular Pharmacology ·Ling Zou, Adrian Stecuła, Anshul Gupta, Bhagwat Prasad, Huan‐Chieh Chien, Sook Wah Yee, (unknown), Jashvant D. Unadkat, Simone H. Stahl, Katherine S. Fenner, Kathleen M. Giacomini	34
12	Mutations in the fourth β-propeller domain of LRP4 are associated with isolated syndactyly with fusion of the third and fourth fingers 2018 ·Human Mutation ·Rivka Sukenik‐Halevy, Huan‐Chieh Chien, (unknown), Michael J. Bamshad, Deborah A. Nickerson, Martin Kircher, Nadav Ahituv	17
13	Reevaluating the Substrate Specificity of the L-Type Amino Acid Transporter (LAT1) 2018 ·Journal of Medicinal Chemistry ·Huan‐Chieh Chien, Claire Colas, (unknown), (unknown), (unknown), Arik A. Zur, (unknown), (unknown), (unknown), Andrew Flint, (unknown), Christopher Hernandez, (unknown), (unknown), (unknown), (unknown), Dimitrios Fotiadis, Avner Schlessinger, Kathleen M. Giacomini, Allen A. Thomas	62
14	A placental growth factor is silenced in mouse embryos by the zinc finger protein ZFP568 2017 ·Science ·Peng Yang, Yixuan Wang, Don Hoang, (unknown), Anamika Patel, Ming‐an Sun, Gernot Wolf, (unknown), Huan‐Chieh Chien, (unknown), Xiaodong Cheng, Che-Kun James Shen, Todd S. Macfarlan	45
15	Discovery of Competitive and Noncompetitive Ligands of the Organic Cation Transporter 1 (OCT1; SLC22A1) 2017 ·Journal of Medicinal Chemistry ·Eugene C. Chen, Natalia Khuri, Xiaomin Liang, Adrian Stecuła, Huan‐Chieh Chien, Sook Wah Yee, Yong Huang, Andrej Săli, Kathleen M. Giacomini	55
16	LAT-1 activity of meta-substituted phenylalanine and tyrosine analogs 2016 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), (unknown), Arik A. Zur, (unknown), (unknown), Huan‐Chieh Chien, Lawrence Lin, Kathleen M. Giacomini, Claire Colas, Avner Schlessinger, Allen A. Thomas	44
17	LAT1 activity of carboxylic acid bioisosteres: Evaluation of hydroxamic acids as substrates 2016 ·Bioorganic & Medicinal Chemistry Letters ·Arik A. Zur, Huan‐Chieh Chien, (unknown), Andrew Flint, (unknown), (unknown), Christopher Hernandez, (unknown), Sydney Miller, Lawrence Lin, Kathleen M. Giacomini, Claire Colas, Avner Schlessinger, Allen A. Thomas	42
18	Prediction and validation of enzyme and transporter off-targets for metformin 2015 ·Journal of Pharmacokinetics and Pharmacodynamics ·Sook Wah Yee, Lawrence Lin, Matthew Merski, Michael J. Keiser, (unknown), Youcai Zhang, Huan‐Chieh Chien, Brian K. Shoichet, Kathleen M. Giacomini	41
19	OCT1 is a high-capacity thiamine transporter that regulates hepatic steatosis and is a target of metformin 2014 ·Proceedings of the National Academy of Sciences ·Ligong Chen, Yan Shu, Xiaomin Liang, Eugene C. Chen, Sook Wah Yee, Arik A. Zur, Shuanglian Li, Lu Xu, Kayvan R. Keshari, (unknown), Huan‐Chieh Chien, Youcai Zhang, Kari M. Morrissey, Jason Liu, J.M. Ostrem, Noah Younger, John Kurhanewicz, Kevan M. Shokat, Kaveh Ashrafi, Kathleen M. Giacomini	182
20	A long non-coding RNA protects the heart from pathological hypertrophy 2014 ·RePEc: Research Papers in Economics ·Pei Han, Wei Li, (unknown), Jin Yang, Ching Shang, (unknown), Kevin K. Jin, Weihong Xu, Chieh‐Yu Lin, Chien-Jung Lin, Yiqin Xiong, Huan‐Chieh Chien, (unknown), Euan A. Ashley, Daniel Bernstein, Peng‐Sheng Chen, Huei‐Sheng Vincent Chen, Thomas Quertermous, Ching‐Pin Chang	1

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact