Kenneth R. Brouwer

2.7k total citations
54 papers, 2.1k citations indexed

About

Kenneth R. Brouwer is a scholar working on Oncology, Pediatrics, Perinatology and Child Health and Pharmacology. According to data from OpenAlex, Kenneth R. Brouwer has authored 54 papers receiving a total of 2.1k indexed citations (citations by other indexed papers that have themselves been cited), including 36 papers in Oncology, 17 papers in Pediatrics, Perinatology and Child Health and 16 papers in Pharmacology. Recurrent topics in Kenneth R. Brouwer's work include Drug Transport and Resistance Mechanisms (35 papers), Pharmacological Effects and Toxicity Studies (16 papers) and Drug-Induced Hepatotoxicity and Protection (11 papers). Kenneth R. Brouwer is often cited by papers focused on Drug Transport and Resistance Mechanisms (35 papers), Pharmacological Effects and Toxicity Studies (16 papers) and Drug-Induced Hepatotoxicity and Protection (11 papers). Kenneth R. Brouwer collaborates with scholars based in United States, Netherlands and United Kingdom. Kenneth R. Brouwer's co-authors include Kim L. R. Brouwer, Edward L. LeCluyse, Gary M. Pollack, Stephen P. Letrent, Joseph W. Polli, Xingrong Liu, Joseph L. Woolley, Robert L. St. Claire, Joan E. Humphreys and Jeffrey E. Edwards and has published in prestigious journals such as PLoS ONE, FEBS Letters and Antimicrobial Agents and Chemotherapy.

In The Last Decade

Kenneth R. Brouwer

52 papers receiving 2.0k citations

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name h Career Trend Papers Cites
Kenneth R. Brouwer United States 24 1.4k 749 647 283 277 54 2.1k
Maciej J. Zamek‐Gliszczynski United States 33 2.0k 1.5× 1.1k 1.5× 945 1.5× 144 0.5× 670 2.4× 62 2.9k
Mahfoud Assem United States 22 1.4k 1.0× 722 1.0× 1.5k 2.4× 106 0.4× 851 3.1× 33 3.2k
Masayo Yamazaki Japan 20 1.2k 0.9× 723 1.0× 533 0.8× 57 0.2× 435 1.6× 33 2.0k
Patrick Caron Canada 30 770 0.6× 312 0.4× 595 0.9× 168 0.6× 778 2.8× 80 2.4k
Paul B. Watkins United States 15 1.0k 0.7× 531 0.7× 956 1.5× 74 0.3× 227 0.8× 20 1.7k
A. David Rodrigues United States 26 772 0.6× 328 0.4× 924 1.4× 117 0.4× 416 1.5× 49 1.8k
Toru Horie Japan 16 893 0.6× 404 0.5× 581 0.9× 124 0.4× 285 1.0× 30 1.4k
Katherine S. Fenner United Kingdom 20 1.0k 0.7× 483 0.6× 619 1.0× 69 0.2× 337 1.2× 28 1.7k
Darlene Barr United States 16 547 0.4× 263 0.4× 644 1.0× 164 0.6× 300 1.1× 33 1.6k
Robert Elsby United Kingdom 20 729 0.5× 363 0.5× 551 0.9× 94 0.3× 367 1.3× 25 1.6k

Countries citing papers authored by Kenneth R. Brouwer

Since Specialization
Citations

This map shows the geographic impact of Kenneth R. Brouwer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Kenneth R. Brouwer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Kenneth R. Brouwer more than expected).

Fields of papers citing papers by Kenneth R. Brouwer

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Kenneth R. Brouwer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Kenneth R. Brouwer. The network helps show where Kenneth R. Brouwer may publish in the future.

Co-authorship network of co-authors of Kenneth R. Brouwer

This figure shows the co-authorship network connecting the top 25 collaborators of Kenneth R. Brouwer. A scholar is included among the top collaborators of Kenneth R. Brouwer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Kenneth R. Brouwer. Kenneth R. Brouwer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
1.
Roe, Amy L., Rachel Wilcox, Lijuan Li, et al.. (2019). An Evaluation of Potential Inhibition of CYP3A4/5 and CYP2C9 Enzymatic Activity by Boswellia serrata Extract. 5(1). 34–46. 8 indexed citations
2.
Jackson, Jonathan P. & Kenneth R. Brouwer. (2019). The C-DILI™ Assay: An Integrated In Vitro Approach to Predict Cholestatic Hepatotoxicity. Methods in molecular biology. 1981. 75–85. 4 indexed citations
3.
Jackson, Jonathan P., Kimberly Freeman, Robert L. St. Claire, Chris Black, & Kenneth R. Brouwer. (2018). Cholestatic Drug Induced Liver Injury: A Function of Bile Salt Export Pump Inhibition and Farnesoid X Receptor Antagonism. 4(3). 265–279. 19 indexed citations
4.
Guo, Cen, Kyunghee Yang, Mingxiang Liao, et al.. (2017). Prediction of Hepatic Efflux Transporter-Mediated Drug Interactions: When Is it Optimal to Measure Intracellular Unbound Fraction of Inhibitors?. Journal of Pharmaceutical Sciences. 106(9). 2401–2406. 5 indexed citations
5.
Brouwer, Kenneth R., Stephen Ferguson, Yurong Lai, et al.. (2016). The Importance of In Vitro Liver Models: Experts Discuss Whole-Cell Systems, Transporter Function, and the Best Models for Future In Vitro Testing. 2(1). 1–7. 4 indexed citations
6.
Jackson, Jonathan P., et al.. (2016). Basolateral Efflux Transporters: A Potentially Important Pathway for the Prevention of Cholestatic Hepatotoxicity. 2(4). 207–216. 25 indexed citations
7.
Roe, Amy L., Mary F. Paine, Bill J. Gurley, et al.. (2016). Assessing Natural Product–Drug Interactions: An End-to-End Safety Framework. Regulatory Toxicology and Pharmacology. 76. 1–6. 28 indexed citations
8.
Lu, Yang, Kenneth R. Brouwer, Kimberly Freeman, et al.. (2016). Hepatocellular Disposition and Transporter Interactions with Tolvaptan and Metabolites in Sandwich-Cultured Human Hepatocytes. Drug Metabolism and Disposition. 44(6). 867–870. 16 indexed citations
9.
Lu, Yang, Kenneth R. Brouwer, Robert L. St. Claire, et al.. (2015). Inhibition of Human Hepatic Bile Acid Transporters by Tolvaptan and Metabolites: Contributing Factors to Drug-Induced Liver Injury?. Toxicological Sciences. 149(1). 237–250. 40 indexed citations
10.
11.
Ansede, John H., Matthew Wright, Robert L. St. Claire, et al.. (2009). Characterization of Sandwich-Cultured Hepatocytes As an in Vitro Model to Assess the Hepatobiliary Disposition of Copper. Drug Metabolism and Disposition. 37(5). 969–976. 5 indexed citations
12.
Edwards, Jeffrey E., Kenneth R. Brouwer, & Patrick J. McNamara. (2002). GF120918, a P-Glycoprotein Modulator, Increases the Concentration of Unbound Amprenavir in the Central Nervous System in Rats. Antimicrobial Agents and Chemotherapy. 46(7). 2284–2286. 50 indexed citations
13.
Kemper, E. Marleen, Bas C. Jansen, Kenneth R. Brouwer, et al.. (2001). Bioanalysis and preliminary pharmacokinetics of the acridonecarboxamide derivative GF120918 in plasma of mice and humans by ion-pairing reversed-phase high-performance liquid chromatography with fluorescence detection. Journal of Chromatography B Biomedical Sciences and Applications. 759(1). 135–143. 11 indexed citations
14.
Liu, Xingrong, Edward L. LeCluyse, Kenneth R. Brouwer, et al.. (1999). Use of Ca2+ Modulation to Evaluate Biliary Excretion in Sandwich-Cultured Rat Hepatocytes. Journal of Pharmacology and Experimental Therapeutics. 289(3). 1592–1599. 103 indexed citations
15.
Polli, Joseph W., et al.. (1999). Role of P-Glycoprotein on the CNS Disposition of Amprenavir (141W94), an HIV Protease Inhibitor. Pharmaceutical Research. 16(8). 1206–1212. 185 indexed citations
16.
Liu, Xingrong, et al.. (1999). Correlation of Biliary Excretion in Sandwich-Cultured Rat Hepatocytes and In Vivo in Rats. Drug Metabolism and Disposition. 27(6). 637–644. 185 indexed citations
17.
Liu, Xingrong, Kim L. R. Brouwer, Kenneth R. Brouwer, et al.. (1998). Partial Maintenance of Taurocholate Uptake by Adult Rat Hepatocytes Cultured in a Collagen Sandwich Configuration. Pharmaceutical Research. 15(10). 1533–1539. 65 indexed citations
18.
Hsyu, P., et al.. (1994). Validation of a liquid chromatography post-column derivatization assay for the determination of cisplatin in plasma. Journal of Pharmaceutical and Biomedical Analysis. 12(2). 265–271. 19 indexed citations
19.
Brouwer, Kenneth R. & Patrick J. McNamara. (1989). Influence of pregnancy on the pharmacokinetic disposition of two aromatic retinoids (etretinate and acitretin) in the rat. I. Intravenous studies.. Drug Metabolism and Disposition. 17(6). 646–651. 2 indexed citations
20.
Brouwer, Kenneth R. & Patrick J. McNamara. (1986). Use of Simultaneous Computer Fitting to Estimate the Apparent Absorption Rate Constant. Journal of Pharmaceutical Sciences. 75(5). 452–455. 2 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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