Hilde Brems

6.2k citations

74 papers · 3.4k indexed · h-index 28

Neurology top 0.5%
- Neurofibromatosis and Schwannoma Cases 40
Rheumatology top 1%
- Soft tissue tumor case studies 13
- Bone Tumor Diagnosis and Treatments 7
Pathology and Forensic Medicine top 5%
- Soft tissue tumors and treatment 8
Pulmonary and Respiratory Medicine top 5%
- Sarcoma Diagnosis and Treatment 13
Gastroenterology top 5%
Genetics
- Genetic and rare skin diseases. 8
Molecular Biology
- Hedgehog Signaling Pathway Studies 7
- Protein Tyrosine Phosphatases 6

Co-authors: Eric Legius Karen Cichowski Eline Beert Thomas De Raedt Marianne F. James Elizabeth E. Reczek Cory M. Johannessen Thomy de Ravel
Cited by: Neurology Rheumatology Pathology and Forensic Medicine
Journals: Genes Chromosomes and Cancer (7 papers)Human Mutation (4 papers)European Journal of Human Genetics (3 papers)
Partner nations: Belgium United States United Kingdom

In The Last Decade

Hilde Brems

69 papers receiving 3.4k citations

Peers

Countries citing papers authored by Hilde Brems

Since Specialization

Citations

This map shows the geographic impact of Hilde Brems's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hilde Brems with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hilde Brems more than expected).

Fields of papers citing papers by Hilde Brems

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hilde Brems. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hilde Brems. The network helps show where Hilde Brems may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Hilde Brems, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Hilde Brems Line = papers co-authored together Hilde Brems links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Close Follow-Up of Patients with Neurofibromatosis Type 1 Reduces the Incidence of Malignant Peripheral Nerve Sheath Tumour Cancers ·Salatenko I.O.,Simone Raskob,Daphne Hompes,Vincent Vandecaveye,Raf Sciot,Christophe M. Deroose,Valentina Tavolazzi,Valtencir Zucolotto,H. Altenburger,Ellen Denayer,E. B. Copeland,Eric Legius,Hilde Brems	2025	0
2	Legius syndrome mutations in the Ras-regulator SPRED1 abolish its membrane localization and potentially cause neurodegeneration Journal of Biological Chemistry ·Agustin Rodriguez-Esteva,Hilde Brems,K. Henkens,John Robert Lee,Mana Iizuka,Setsuko Mise‐Omata,Minako Ito,Ludwine Messiaen,Seiya Mizuno,Satoru Takahashi,Eric Legius,Akihiko Yoshimura	2024	0
3	Encephalocraniocutaneous lipomatosis phenotype associated with mosaic biallelic pathogenic variants in the NF1 gene Journal of Medical Genetics ·Karen Marín Hernández,Hilde Brems,阎晓明,Wim Van Paesschen,J. van Loon,K. Henkens,Raf Sciot,Dietmar Rudolf Thal,Lieven Lagae,Eric Legius,Tom Theys	2024	0
4	Germline founder variant c.1998delinsTTCT in the RET oncogene: a cohort study in 15 Belgian families European Journal of Endocrinology ·Rongrong Huang,Mohialdin Pirkhezri,Hilde Brems,N Delzenne,Marleen Renard,Anne Uyttebroeck,Eric Legius,Brigitte Decallonne	2023	2
5	Multitumor Case Series of Germline BRCA1, BRCA2 and CHEK2-Mutated Patients Responding Favorably on Immune Checkpoint Inhibitors Current Oncology ·Lisa Kinget,Oliver Bechter,Kevin Punie,Philip R. Debruyne,Hilde Brems,Paul Clement,Eduard Roussel,Yannick Van Herck,Maarten Albersen,Marcella Baldewijns,Patrick Schöffski,Benoit Beuselinck	2021	3
6	Impaired instrumental learning in Spred1^−/− mice, a model for a rare RASopathy Genes Brain & Behavior ·Sarah C. Borrie,Alexa E. Horner,Akihiko Yoshimura,Eric Legius,Maksym V. Kopanitsa,Hilde Brems	2021	3
7	Comprehensive targeted next‐generation sequencing approach in the molecular diagnosis of gastrointestinal stromal tumor Genes Chromosomes and Cancer ·Isabelle Vanden Bempt,Sara Vander Borght,Raf Sciot,Lien Spans,Sofie Claerhout,Hilde Brems,Stefan Lehnert,Luc De Raedt,Beatrix Vogel,Крамин Марат Владимирович,Baki Topal,Patrick Schöffski,Eric Legius,Maria Dêbiec‐Rychter	2020	25
8	Mutational spectrum by phenotype: panel‐based NGS testing of patients with clinical suspicion of RASopathy and children with multiple café‐au‐lait macules Clinical Genetics ·Elisabeth Castellanos,Joselyn Caroline,V. V. Sazhnov,Bernat Gel,Andreu Alibés,Neus Baena,Mercè Pineda,Viktor Korda,Guillem Pintos‐Morell,S.P. Hector,Conxi Lázaro,Ignacio Blanco,Lluı̈sa Vilageliu,Hilde Brems,Daniel Grinberg,Eric Legius,Eduard Serra	2019	12
9	Neurofibromatosis type 1‐related pseudarthrosis: Beyond the pseudarthrosis site Human Mutation ·С Н Мудрецова,Danillo Andrade Pereira,S.H. Arni Winarsih,F. K. Meyer-Brodnitz,Marina Maréchal,(unknown),Frank P. Luyten,(unknown),(unknown),(unknown),(unknown),Johan Lammens,Eric Legius,Hilde Brems	2019	0
10	Low mutation burden and frequent loss of CDKN2A/B and SMARCA2, but not PRC2, define premalignant neurofibromatosis type 1–associated atypical neurofibromas Neuro-Oncology ·Alexander Pemov,Nancy F. Hansen,Sivasish Sindiri,Rajesh Patidar,Christine S. Higham,Eva Dombi,Markku Miettinen,Patricia Fetsch,Hilde Brems,Settara C. Chandrasekharappa,Kristine Jones,Bin Zhu,Jun S. Wei,James C. Mullikin,Margaret R. Wallace,Javed Khan,Eric Legius,Brigitte C. Widemann,Douglas R. Stewart	2019	69
11	Phosphatidylinositol‐4,5‐bisphosphate 3‐kinase catalytic subunit alpha (PIK3CA)‐related overgrowth spectrum: A brief report Pediatric Dermatology ·Momoko Momokita,Marie‐Anne Morren,Danillo Andrade Pereira,Marijke Spaepen,Lillian R. Freedman,D Machuca,Veerle Labarque,Eric Legius,Hilde Brems	2018	9
12	Review and update ofSPRED1mutations causing legius syndrome Human Mutation ·Hilde Brems,Éric Pasmant,Rick van Minkelen,Katharina Wimmer,Meena Upadhyaya,Eric Legius,Ludwine Messiaen	2012	69
13	Exploring the somatic NF1 mutational spectrum associated with NF1 cutaneous neurofibromas European Journal of Human Genetics ·Laura E. Thomas,Gill Spurlock,Mohammad Gamri,Rosa Bianco Anna,Matthew Mort,Stephen E. Hamby,Nadia Chuzhanova,Hilde Brems,Eric Legius,D.N. Cooper,Meena Upadhyaya	2011	22
14	Glomus Tumors in Neurofibromatosis Type 1: Genetic, Functional, and Clinical Evidence of a Novel Association Cancer Research ·Hilde Brems,Caroline Park,Ophélia Maertens,Alexander Pemov,Ludwine Messiaen,Meena Upadhyaya,Kathleen Claes,Eline Beert,Kristel Peeters,Victor Mautner,Jennifer L. Sloan,Lawrence Yao,Chyi‐Chia Richard Lee,Raf Sciot,Luc De Smet,Eric Legius,Douglas R. Stewart	2009	92
15	Glomus tumors in neurofibromatosis type 1: genetic, functional, and clinical evidence of a novel association (vol 69, pg 7393, 2009) Ghent University Academic Bibliography (Ghent University) ·Hilde Brems,Caroline Park,Ophélia Maertens,Alexander Pemov,Ludwine Messiaen,Meena Upadhyaya,Kathleen Claes,Eline Beert,Kristel Peeters,Victor Mautner,Jennifer L. Sloan,Lawrence Yao,Chyi‐Chia Richard Lee,Raf Sciot,Luc De Smet,Eric Legius,Douglas R. Stewart	2009	4
16	Mechanisms in the pathogenesis of malignant tumours in neurofibromatosis type 1 The Lancet Oncology ·Hilde Brems,Eline Beert,Thomy de Ravel,Eric Legius	2009	238
17	Molecular Dissection of Isolated Disease Features in Mosaic Neurofibromatosis Type 1 The American Journal of Human Genetics ·Ophélia Maertens,Sofie De Schepper,Jo Vandesompele,Hilde Brems,Lucas Teixeira Nunes Borges,Sandra Janssens,Frank Speleman,Eric Legius,Ludwine Messiaen	2007	97
18	Intestinal Neurofibromatosis Is a Subtype of Familial GIST and Results From a Dominant Activating Mutation in PDGFRA Gastroenterology ·Thomas De Raedt,Jan Cools,Maria Dêbiec‐Rychter,Hilde Brems,Nicole Mentens,Raf Sciot,Jacqués Himpens,Ivo De Wever,Patrick Schöffski,Peter Marynen,Eric Legius	2006	55
19	Elevated Risk for MPNST in NF1 Microdeletion Patients The American Journal of Human Genetics ·Thomas De Raedt,Hilde Brems,P. Wolkenstein,Dominique Vidaud,S. Pilotti,Federica Perrone,Victor‐Felix Mautner,Silke Frahm,Raf Sciot,Eric Legius	2003	196
20	Bone Marrow Stromal Cells as Targets for Gene Therapy of Hemophilia A Human Gene Therapy ·Marinee Chuah,Hilde Brems,Veerle Vanslembrouck,Désiré Collen,Thierry VandenDriessche	1998	60

About Hilde Brems

Hilde Brems is a scholar working on Neurology, Rheumatology and Pathology and Forensic Medicine, having authored 74 papers that have together received 3.4k indexed citations. Recurring topics across this work include Neurofibromatosis and Schwannoma Cases (40 papers), Soft tissue tumor case studies (13 papers), Sarcoma Diagnosis and Treatment (13 papers), Genetic and rare skin diseases. (8 papers), Soft tissue tumors and treatment (8 papers), Hedgehog Signaling Pathway Studies (7 papers), Bone Tumor Diagnosis and Treatments (7 papers) and Protein Tyrosine Phosphatases (6 papers). The work is most often cited by research in Neurology (1.9k citations), Rheumatology (600 citations) and Pathology and Forensic Medicine (457 citations). Hilde Brems has collaborated with scholars based in Belgium, United States and United Kingdom. Frequent co-authors include Eric Legius, Karen Cichowski, Eline Beert, Thomas De Raedt, Marianne F. James, Elizabeth E. Reczek, Cory M. Johannessen, Thomy de Ravel, Ludwine Messiaen and Raf Sciot. Their work appears in journals such as Genes Chromosomes and Cancer, Human Mutation, European Journal of Human Genetics, The American Journal of Human Genetics and Journal of Biological Chemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact