Hideyuki Tomizawa

4.4k total citations · 1 hit paper
24 papers, 3.6k citations indexed

About

Hideyuki Tomizawa is a scholar working on Immunology, Molecular Biology and Organic Chemistry. According to data from OpenAlex, Hideyuki Tomizawa has authored 24 papers receiving a total of 3.6k indexed citations (citations by other indexed papers that have themselves been cited), including 13 papers in Immunology, 8 papers in Molecular Biology and 7 papers in Organic Chemistry. Recurrent topics in Hideyuki Tomizawa's work include Immune Response and Inflammation (13 papers), Quinazolinone synthesis and applications (7 papers) and Immune Cell Function and Interaction (6 papers). Hideyuki Tomizawa is often cited by papers focused on Immune Response and Inflammation (13 papers), Quinazolinone synthesis and applications (7 papers) and Immune Cell Function and Interaction (6 papers). Hideyuki Tomizawa collaborates with scholars based in Japan, United Kingdom and United States. Hideyuki Tomizawa's co-authors include Tsuneyasu Kaisho, Hiroaki Hemmi, Shizuo Akira, Takao Horiuchi, Osamu Takeuchi, Hideki Sanjo, Kiyoshi Takeda, Shintaro Sato, Katsuaki Hoshino and Alexander D. Edwards and has published in prestigious journals such as The Journal of Experimental Medicine, Nature Immunology and The Journal of Immunology.

In The Last Decade

Hideyuki Tomizawa

24 papers receiving 3.5k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway

2002 2.0k citations Hiroaki Hemmi, Tsuneyasu Kaisho et al. Nature Immunology profile →

Peers

Countries citing papers authored by Hideyuki Tomizawa

Since Specialization

Citations

This map shows the geographic impact of Hideyuki Tomizawa's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hideyuki Tomizawa with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hideyuki Tomizawa more than expected).

Fields of papers citing papers by Hideyuki Tomizawa

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hideyuki Tomizawa. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hideyuki Tomizawa. The network helps show where Hideyuki Tomizawa may publish in the future.

Co-authorship network of co-authors of Hideyuki Tomizawa

This figure shows the co-authorship network connecting the top 25 collaborators of Hideyuki Tomizawa. A scholar is included among the top collaborators of Hideyuki Tomizawa based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hideyuki Tomizawa. Hideyuki Tomizawa is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Dihydropyrrolo[2,3-d]pyrimidines: Selective Toll-Like Receptor 9 Antagonists from Scaffold Morphing Efforts 2014 ·ACS Medicinal Chemistry Letters ·Manabu Watanabe, (unknown), Hideyuki Tomizawa, (unknown), (unknown), Yoshiaki Isobe, Shigehiro Asano	22
2	Intratracheal and oral administration of SM‐276001: A selective TLR7 agonist, leads to antitumor efficacy in primary and metastatic models of cancer 2012 ·International Journal of Cancer ·(unknown), Simon J. Dovedi, Masashi Murata, Hiroyuki Matsui, Andrew J. Leishman, John Bell, Douglas Ferguson, Simon P. Heaton, (unknown), Hideyuki Tomizawa, (unknown), Haruo Takaku, Robert W. Wilkinson, Hideyuki Harada	23
3	Biological characterization of a novel class of toll‐like receptor 7 agonists designed to have reduced systemic activity 2011 ·British Journal of Pharmacology ·Mark Biffen, Hiroyuki Matsui, (unknown), Andrew J. Leishman, (unknown), (unknown), (unknown), Ian Doyle, Hiroki Wada, (unknown), (unknown), Mikio Aoki, Hideyuki Tomizawa, (unknown), Haruo Takaku, Tom McInally, Clare Murray	30
4	Biological Activity Of Novel TLR7 Ante-drug Agonists For The Treatment Of Allergic Diseases 2010 ·Mark Biffen, Hiroyuki Matsui, (unknown), (unknown), Ian Doyle, (unknown), Andrew J. Leishman, (unknown), (unknown), Hideyuki Tomizawa, Haruo Takaku, Clare Murray	2
5	Mechanisms Of Inhibition Of Type-2 Cytokines By Novel Ante-drug TLR7 Agonists 2010 ·Hiroyuki Matsui, Hideyuki Tomizawa, (unknown), (unknown), Mark Biffen, Andrew J. Leishman, Clare Murray, Haruo Takaku, Hideya Hayashi	2
6	Structure–Activity relationships of 6-fluoroquinazolines: dual-Acting compounds with inhibitory activities toward both TNF-α production and T cell proliferation 2003 ·Bioorganic & Medicinal Chemistry ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, (unknown), (unknown), Hideya Hayashi	27
7	Discovery of quinazolines as a novel structural class of potent inhibitors of NF-κB activation 2003 ·Bioorganic & Medicinal Chemistry ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, (unknown), Hirotada Takahashi, Tominaga Fukazawa, Hideya Hayashi	139
8	Expression and Function of Toll-Like Receptors in Eosinophils: Activation by Toll-Like Receptor 7 Ligand 2003 ·The Journal of Immunology ·Hiroyuki Nagase, Shu Okugawa, Yasuo Ota, Masao Yamaguchi, Hideyuki Tomizawa, Kouji Matsushima, Ken Ohta, Kazuhiko Yamamoto, Koichi Hirai	239
9	Toll‐like receptor expression in murine DC subsets: lack of TLR7 expression by CD8α⁺ DC correlates with unresponsiveness to imidazoquinolines 2003 ·European Journal of Immunology ·Alexander D. Edwards, Sandra S. Diebold, Emma Slack, Hideyuki Tomizawa, Hiroaki Hemmi, Tsuneyasu Kaisho, Shizuo Akira, Caetano Reis e Sousa	454
10	A novel structural class of potent inhibitors of NF-κB activation: structure–activity relationships and biological effects of 6-aminoquinazoline derivatives 2003 ·Bioorganic & Medicinal Chemistry ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, (unknown), Hirotada Takahashi, Hideya Hayashi	63
11	Structure—Activity Relationships of 6‐Nitroquinazolines: Dual‐Acting Compounds with Inhibitory Activities Toward both TNF‐α Production and T Cell Proliferation. 2003 ·ChemInform ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, (unknown), (unknown), Mitsuhiro Matsumoto, Hideya Hayashi	1
12	Interferon-α and Interleukin-12 Are Induced Differentially by Toll-like Receptor 7 Ligands in Human Blood Dendritic Cell Subsets 2002 ·The Journal of Experimental Medicine ·Tomoki� Ito, Ryuichi Amakawa, Tsuneyasu Kaisho, Hiroaki Hemmi, Kenichirou Tajima, Kazutaka Uehira, Yoshio Ozaki, Hideyuki Tomizawa, Shizuo Akira, Shirou Fukuhara	360
13	Small anti-viral compounds activate immune cells via the TLR7 MyD88–dependent signaling pathway breakdown → 2002 ·Nature Immunology ·Hiroaki Hemmi, Tsuneyasu Kaisho, Osamu Takeuchi, Shintaro Sato, Hideki Sanjo, Katsuaki Hoshino, Takao Horiuchi, Hideyuki Tomizawa, Kiyoshi Takeda, Shizuo Akira	1972
14	Structure-Activity Relationships of 6-Nitroquinazolines: Dual-Acting Compounds with Inhibitory Activities toward both TNF-.ALPHA. Production and T Cell Proliferation. 2002 ·Chemical and Pharmaceutical Bulletin ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, (unknown), (unknown), Mitsuhiro Matsumoto, Hideya Hayashi	8
15	Structure–activity relationships of quinazoline derivatives: dual-acting compounds with inhibitory activities toward both TNF-α production and T Cell proliferation 2001 ·Bioorganic & Medicinal Chemistry Letters ·Masanori Tobe, Yoshiaki Isobe, Hideyuki Tomizawa, Mitsuhiro Matsumoto, (unknown), (unknown), Hideya Hayashi	17
16	Stabilization of Lysozyme against Irreversible Inactivation by Suppression of Chemical Reactions 1995 ·The Journal of Biochemistry ·Hideyuki Tomizawa, Hidenori Yamada, (unknown), (unknown)	32
17	Stabilization of lysozyme against irreversible inactivation by alterations of the Asp-Gly sequences 1995 ·Protein Engineering Design and Selection ·Hideyuki Tomizawa, Hidenori Yamada, Yoshio Hashimoto, Taiji Imoto	15
18	Effects of Additives on Irreversible Inactivation of Lysozyme at Neutral pH and 100 C 1995 ·The Journal of Biochemistry ·Hideyuki Tomizawa, Hidenori Yamada, K. Tanigawa, (unknown)	21
19	Isolation and Characterization of 101-Succinimide Lysozyme That Possesses the Cyclic Imide at Asp101-Gly102 1994 ·Biochemistry ·Hideyuki Tomizawa, Hidenori Yamada, (unknown), Taiji Imoto	36
20	The Mechanism of Irreversible Inactivation of Lysozyme at pH 4 and 100 .degree.C 1994 ·Biochemistry ·Hideyuki Tomizawa, Hidenori Yamada, Taiji Imoto	44

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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