Hideyuki Takeuchi

10.4k total citations · 2 hit papers
160 papers, 7.7k citations indexed

About

Hideyuki Takeuchi is a scholar working on Neurology, Molecular Biology and Neurology. According to data from OpenAlex, Hideyuki Takeuchi has authored 160 papers receiving a total of 7.7k indexed citations (citations by other indexed papers that have themselves been cited), including 57 papers in Neurology, 34 papers in Molecular Biology and 34 papers in Neurology. Recurrent topics in Hideyuki Takeuchi's work include Neuroinflammation and Neurodegeneration Mechanisms (53 papers), Amyotrophic Lateral Sclerosis Research (18 papers) and Alzheimer's disease research and treatments (15 papers). Hideyuki Takeuchi is often cited by papers focused on Neuroinflammation and Neurodegeneration Mechanisms (53 papers), Amyotrophic Lateral Sclerosis Research (18 papers) and Alzheimer's disease research and treatments (15 papers). Hideyuki Takeuchi collaborates with scholars based in Japan, Slovakia and United States. Hideyuki Takeuchi's co-authors include Akio Suzumura, Tetsuya Mizuno, Jun Kawanokuchi, Yoshifumi Sonobe, Shijie Jin, Reiko Kuno, Bijay Parajuli, Jinyan Wang, Yukiko Doi and Guiqin Zhang and has published in prestigious journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and Journal of Clinical Oncology.

In The Last Decade

Hideyuki Takeuchi

148 papers receiving 7.6k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Tumor Necrosis Factor-α Induces Neurotoxicity via Glutamate Release from Hemichannels of Activated Microglia in an Autocrine Manner

2006 619 citations Hideyuki Takeuchi, Shijie Jin et al. Journal of Biological Chemistry profile →
Minocycline selectively inhibits M1 polarization of microglia

2013 594 citations Hideyuki Takeuchi, Akio Suzumura et al. profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Hideyuki Takeuchi Japan	48	3.1k	2.4k	1.7k	1.5k	1.3k	160	7.7k
Stella E. Tsirka United States	53	3.3k 1.1×	3.3k 1.4×	1.6k 1.0×	907 0.6×	1.3k 1.0×	145	10.0k
Kaoru Saijo Japan	33	2.5k 0.8×	3.2k 1.3×	3.1k 1.9×	1.2k 0.8×	674 0.5×	76	9.1k
Jae Kyu Ryu Canada	45	2.6k 0.8×	1.7k 0.7×	872 0.5×	1.5k 1.0×	768 0.6×	73	6.4k
Tetsuya Mizuno Japan	49	2.8k 0.9×	2.1k 0.9×	2.0k 1.2×	1.4k 0.9×	613 0.5×	169	7.8k
Craig S. Moore Canada	37	3.7k 1.2×	2.1k 0.8×	2.6k 1.5×	836 0.6×	739 0.6×	94	7.5k
Xiaoming Hu United States	61	7.1k 2.3×	3.8k 1.6×	3.2k 2.0×	1.3k 0.9×	1.9k 1.5×	147	12.8k
Bart J. L. Eggen Netherlands	46	3.8k 1.2×	2.3k 0.9×	2.3k 1.4×	1.2k 0.8×	366 0.3×	144	7.5k
David J. Loane United States	52	3.4k 1.1×	3.7k 1.5×	1.5k 0.9×	850 0.6×	3.9k 2.9×	81	9.3k
Jack van Horssen Netherlands	58	3.4k 1.1×	4.2k 1.7×	2.0k 1.2×	1.5k 1.0×	1.2k 0.9×	116	10.2k
Junya Tanaka Japan	48	2.1k 0.7×	2.5k 1.0×	1.5k 0.9×	1.0k 0.7×	570 0.4×	179	7.2k

Countries citing papers authored by Hideyuki Takeuchi

Since Specialization

Citations

This map shows the geographic impact of Hideyuki Takeuchi's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Hideyuki Takeuchi with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Hideyuki Takeuchi more than expected).

Fields of papers citing papers by Hideyuki Takeuchi

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Hideyuki Takeuchi. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Hideyuki Takeuchi. The network helps show where Hideyuki Takeuchi may publish in the future.

Co-authorship network of co-authors of Hideyuki Takeuchi

This figure shows the co-authorship network connecting the top 25 collaborators of Hideyuki Takeuchi. A scholar is included among the top collaborators of Hideyuki Takeuchi based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Hideyuki Takeuchi. Hideyuki Takeuchi is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Takeuchi, Hideyuki, Yuki Ogawa, S. Kubota, et al.. (2025). Siponimod inhibits microglial inflammasome activation. Neuroscience Research. 213. 138–145. 2 indexed citations

Fujisawa, Haruki, Takashi Watanabe, Okiru Komine, et al.. (2024). Prolonged extracellular low sodium concentrations and subsequent their rapid correction modulate nitric oxide production dependent on NFAT5 in microglia. Free Radical Biology and Medicine. 223. 458–472. 1 indexed citations

Fujisawa, Haruki, Naoko Iwata, Takashi Watanabe, et al.. (2024). Effects of hypernatremia on the microglia. Peptides. 179. 171267–171267. 3 indexed citations

Tsuboi, Kazuto, Takahiro Masuda, Nobuo Omura, et al.. (2023). Is it meaningful to add mesh reinforcement to laparoscopic fundoplication for esophageal hiatal hernias in the patients with high risk of hiatal hernia recurrence?. Esophagus. 21(1). 67–75. 1 indexed citations

Tsuboi, Kazuto, Masato Hoshino, Nobuo Omura, et al.. (2022). The pathological conditions and surgical outcomes depending on the degree of hernia in the intra-thoracic stomach. Esophagus. 20(3). 573–580.

Niino, Masaaki, Tatsusada Okuno, Nobuo Sanjo, et al.. (2022). Health-related quality of life in Japanese patients with multiple sclerosis. Journal of Neurology. 270(2). 1011–1018. 1 indexed citations

Kishida, Hitaru, et al.. (2021). Neural mechanisms of foreign accent syndrome: Lesion and network analysis. NeuroImage Clinical. 31. 102760–102760. 11 indexed citations

Kunii, Misako, Hiroshi Doi, Toyojiro Matsuishi, et al.. (2020). De novo CACNA1G variants in developmental delay and early-onset epileptic encephalopathies. Journal of the Neurological Sciences. 416. 117047–117047. 11 indexed citations

Yoshida, Masashi, Hironori Ohdaira, Hideyuki Takeuchi, et al.. (2020). Near-infrared fluorescent clip guided gastrectomy: Report of 2 cases (Case reports). Annals of Medicine and Surgery. 55. 49–52. 10 indexed citations

10.

Tanokashira, Daisuke, et al.. (2018). Metformin treatment ameliorates diabetes‐associated decline in hippocampal neurogenesis and memory via phosphorylation of insulin receptor substrate 1. FEBS Open Bio. 8(7). 1104–1118. 66 indexed citations

11.

Nakae, Yoshiharu, Hiroshi Doi, Hitaru Kishida, et al.. (2017). White matter hyperintensities on MRI in dementia with Lewy bodies, Parkinson's disease with dementia, and Alzheimer's disease. Journal of the Neurological Sciences. 385. 99–104. 54 indexed citations

12.

Takeuchi, Hideyuki, Shijie Jin, Bijay Parajuli, et al.. (2016). Conditioned Medium from the Stem Cells of Human Exfoliated Deciduous Teeth Ameliorates Experimental Autoimmune Encephalomyelitis. The Journal of Immunology. 196(10). 4164–4171. 80 indexed citations

13.

Takeuchi, Hideyuki, et al.. (2012). Effects of levocarnitine in hemodialysis patients. Nihon Toseki Igakkai Zasshi. 45(10). 955–963. 2 indexed citations

14.

Mizuno, Tetsuya, Yukiko Doi, Hiroyuki Mizoguchi, et al.. (2011). Interleukin-34 Selectively Enhances the Neuroprotective Effects of Microglia to Attenuate Oligomeric Amyloid-β Neurotoxicity. American Journal Of Pathology. 179(4). 2016–2027. 123 indexed citations

15.

Liang, Jianfeng, Hideyuki Takeuchi, Shijie Jin, et al.. (2010). Glutamate induces neurotrophic factor production from microglia via protein kinase C pathway. Brain Research. 1322. 8–23. 47 indexed citations

16.

Noda, Mariko, Yukiko Doi, Jianfeng Liang, et al.. (2010). Fractalkine Attenuates Excito-neurotoxicity via Microglial Clearance of Damaged Neurons and Antioxidant Enzyme Heme Oxygenase-1 Expression. Journal of Biological Chemistry. 286(3). 2308–2319. 123 indexed citations

17.

Sonobe, Yoshifumi, Shijie Jin, Guiqin Zhang, et al.. (2008). Microglia express a functional receptor for interleukin-23. Biochemical and Biophysical Research Communications. 370(1). 129–133. 22 indexed citations

18.

Ohashi, Toshimitsu, et al.. (2007). A Case of a Foreign Body Penetrating the Trachea and Lodging into the Cervical Region. Practica Oto-Rhino-Laryngologica. 100(9). 753–756. 1 indexed citations

19.

Takeuchi, Hideyuki, et al.. (2007). Questionnaire survey of complaints and acupuncture treatment in maintenance hemodialysis patients. Nihon Toseki Igakkai Zasshi. 40(6). 513–516. 3 indexed citations

20.

Yoshihara, Tsuyoshi, Shinsuke Ishigaki, Masahiko Yamamoto, et al.. (2001). Differential expression of inflammation‐ and apoptosis‐related genes in spinal cords of a mutant SOD1 transgenic mouse  model of familial amyotrophic lateral sclerosis. Journal of Neurochemistry. 80(1). 158–167. 229 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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