Haruhiko Takada

12.7k citations

173 papers · 10.3k indexed · 1 hit paper · h-index 48

Immunology top 0.2%
Molecular Biology top 2%
Epidemiology top 2%
Microbiology top 0.1%
Periodontics top 0.2%

Co-authors: Shizuo Akira Osamu Takeuchi Tomohiko Ogawa Kiyoshi Takeda Akiko Uehara Taro Kawai Katsuaki Hoshino Hideki Sanjo
Topics: Immune Response and Inflammation (85 papers)Antimicrobial Peptides and Activities (40 papers)Oral microbiology and periodontitis research (27 papers)
Cited by: Immunology Periodontics Microbiology
Journals: Proceedings of the National Academy of Sciences Journal of Biological Chemistry The Journal of Experimental Medicine
Partner nations: Japan United States Poland

In The Last Decade

Haruhiko Takada

171 papers receiving 10.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Differential Roles of TLR2 and TLR4 in Recognition of Gram-Negative and Gram-Positive Bacterial Cell Wall Components

1999 2.8k citations Haruhiko Takada, Tomohiko Ogawa et al. profile →

Peers

Countries citing papers authored by Haruhiko Takada

Since Specialization

Citations

This map shows the geographic impact of Haruhiko Takada's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Haruhiko Takada with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Haruhiko Takada more than expected).

Fields of papers citing papers by Haruhiko Takada

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Haruhiko Takada. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Haruhiko Takada. The network helps show where Haruhiko Takada may publish in the future.

Co-authorship network of co-authors of Haruhiko Takada

This figure shows the co-authorship network connecting the top 25 collaborators of Haruhiko Takada. A scholar is included among the top collaborators of Haruhiko Takada based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Haruhiko Takada. Haruhiko Takada is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	NSAIDs suppress the expression of claudin-2 to promote invasion activity of cancer cells 2008 ·Carcinogenesis ·S. Mima,Mikio Takehara,Haruhiko Takada,Tomoko Nishimura,Tatsuya Hoshino,T. Mizushima	22
2	Antibodies to proteinase 3 prime human monocytic cells via protease-activated receptor-2 and NF-κB for Toll-like receptor- and NOD-dependent activation 2007 ·Molecular Immunology ·Akiko Uehara,(unknown),Tadasu Sato,(unknown),Haruhiko Takada	27
3	Muramyl Dipeptide Enhances Osteoclast Formation Induced by Lipopolysaccharide, IL-1α, and TNF-α through Nucleotide-Binding Oligomerization Domain 2-Mediated Signaling in Osteoblasts 2005 ·The Journal of Immunology ·Shuhua Yang,Naoyuki Takahashi,Teruhito Yamashita,Nobuaki Sato,Masahiro Takahashi,Makio Mogi,Takashi Uematsu,Yasuhiro Kobayashi,Yuko Nakamichi,Kiyoshi Takeda,Shizuo Akira,Haruhiko Takada,Nobuyuki Udagawa,Kiyofumi Furusawa	64
4	Arginine-Specific Gingipains from Porphyromonas gingivalis Stimulate Production of Hepatocyte Growth Factor (Scatter Factor) through Protease-Activated Receptors in Human Gingival Fibroblasts in Culture 2005 ·The Journal of Immunology ·Akiko Uehara,Koji Muramoto,Takahisa Imamura,Koji Nakayama,Jan Potempa,James Travis,Shunji Sugawara,Haruhiko Takada	41
5	Contrasting responses of human gingival and periodontal ligament fibroblasts to bacterial cell‐surface components through the CD14/Toll‐like receptor system 2003 ·Oral Microbiology and Immunology ·(unknown),Riyoko Tamai,A. Sugiyama,Sachiko Akashi,Shunji Sugawara,Haruhiko Takada	88
6	Overexpression of a pattern-recognition receptor, peptidoglycan-recognition protein-LE, activates imd/relish-mediated antibacterial defense and the prophenoloxidase cascade in Drosophila larvae 2002 ·Proceedings of the National Academy of Sciences ·(unknown),Tomonori Katsuyama,Tamaki Yano,Yoshiteru Oshima,Haruhiko Takada,Toshiro Aigaki,Shoichiro Kurata	278
7	Neutrophil Proteinase 3-Mediated Induction of Bioactive IL-18 Secretion by Human Oral Epithelial Cells 2001 ·The Journal of Immunology ·Shunji Sugawara,Akiko Uehara,Tomonori Nochi,Takahiro Yamaguchi,Haruyasu Ueda,Akiko Sugiyama,(unknown),Katsuo Kumagai,Haruki Okamura,Haruhiko Takada	235
8	Inflammatory Reactions in Extraoral Tissues in Mice after Intragingival Injection of Lipopolysaccharide 2001 ·The Journal of Infectious Diseases ·Hiromi Funayama,Hideaki Mayanagi,Haruhiko Takada,Yasuo Endo	12
9	Contrasting responses of human gingival and colonic epithelial cells to lipopolysaccharides, lipoteichoic acids and peptidoglycans in the presence of soluble CD14 2001 ·Medical Microbiology and Immunology ·Akiko Uehara,Shunji Sugawara,Riyoko Tamai,Haruhiko Takada	54
10	Proteolysis of Human Monocyte CD14 by Cysteine Proteinases (Gingipains) from Porphyromonas gingivalis Leading to Lipopolysaccharide Hyporesponsiveness 2000 ·The Journal of Immunology ·Shunji Sugawara,Eiji Nemoto,Hiroyuki Tada,Kensuke Miyake,Takahisa Imamura,Haruhiko Takada	104
11	Cleavage of CD14 on Human Gingival Fibroblasts Cocultured with Activated Neutrophils Is Mediated by Human Leukocyte Elastase Resulting in Down-Regulation of Lipopolysaccharide-Induced IL-8 Production 2000 ·The Journal of Immunology ·Eiji Nemoto,Shunji Sugawara,Hiroyuki Tada,Haruhiko Takada,Hidetoshi Shimauchi,Hiroshi Horiuchi	38
12	Elevation of histidine decarboxylase activity in the mandible of mice by Prevotella intermedia lipopolysaccharide and its augmentation by an aminobisphosphonate 2000 ·Archives of Oral Biology ·Hiromi Funayama,Hideaki Mayanagi,Haruhiko Takada,Yasuo Endo	28
13	Wax D ofMycobacterium tuberculosisinduced osteomyelitis accompanied by reactive bone formation in Buffalo rats 1998 ·FEMS Immunology & Medical Microbiology ·Yoshihiro Kawabata,Ichiro Semba,(unknown),Toshitaka Koga,Shigeki Nagao,Haruhiko Takada	6
14	A lipoteichoic acid fraction ofEnterococcus hiraeactivates cultured human monocytic cells via a CD14-independent pathway to promote cytokine production, and the activity is inhibited by serum components 1998 ·FEMS Immunology & Medical Microbiology ·Rieko Arakaki,Shunji Sugawara,Hideki Nakashima,Shozo Kotani,Haruhiko Takada	5
15	Micrococcus luteuscells and cell walls induce anaphylactoid reactions accompanied by early death and serum cytokines in mice primed with muramyl dipeptide 1997 ·FEMS Immunology & Medical Microbiology ·(unknown),Yoshihiro Kawabata,Haruhiko Takada	7
16	Interleukin-8 gene expression by human dental pulp fibroblast in cultures stimulated with Prevotella intermedia lipopolysaccharide 1996 ·Journal of Endodontics ·Shigetaka Nagaoka,Masayuki Tokuda,Tetsuya Sakuta,(unknown),Masato Tamura,Haruhiko Takada,M Kawagoe	61
17	Cytokine-inducing glycolipids in the lipoteichoic acid fraction fromEnterococcus hiraeATCC 9790 1995 ·FEMS Immunology & Medical Microbiology ·Yasuo Suda,Hidehito Tochio,(unknown),Haruhiko Takada,Takeshi Yoshida,Shozo Kotani,Shoichi Kusumoto	49
18	Lipopolysaccharides of oral black pigmented bacteria and periodontal diseases. A novel immunomodulator different from endotoxin was extracted from Prevotella intermedia ATCC 25611 with hot phenol-water. 1995 ·PubMed ·Haruhiko Takada,(unknown),Tetsuya Sakuta,A. Sugiyama,(unknown),Shigeyuki Hamada	6
19	A nontoxic tumour necrosis factor induced by streptococcal lipoteichoic acids 1987 ·British Journal of Cancer ·(unknown),Akihiko Yamamoto,Yohei Sugawara,Shigeyuki Hamada,Toshiko Yamamoto,Kimiko Kato,Susumu Kokeguchi,Haruhiko Takada,S Kotani	20
20	A novel immunomodulator derived from Mycobacterium bovis BCG which holds many bioactivities in common with endotoxins. 1987 ·Nippon Saikingaku Zasshi ·(unknown),Shozo Kotani,M Tsujimoto,Tomohiko Ogawa,Haruhiko Takada,Ichiro Takahashi,Hidetoshi Shimauchi,Susumu Kokeguchi,Keijiro Kato,Haruki Okamura,Toshihide Tamura,Ikuya Yano,Shigenori Tanaka,Yoshiko Kato	1

About Haruhiko Takada

Haruhiko Takada is a scholar working on Microbiology, Periodontics and Immunology, having authored 173 papers that have together received 10.3k indexed citations. Recurring topics across this work include Immune Response and Inflammation (85 papers), Antimicrobial Peptides and Activities (40 papers) and Oral microbiology and periodontitis research (27 papers). The work is most often cited by research in Immunology (6.4k citations), Periodontics (1.2k citations) and Microbiology (1.5k citations). Haruhiko Takada has collaborated with scholars based in Japan, United States and Poland. Frequent co-authors include Shizuo Akira, Osamu Takeuchi, Tomohiko Ogawa, Kiyoshi Takeda, Akiko Uehara, Taro Kawai, Katsuaki Hoshino, Hideki Sanjo, Shunji Sugawara and Koichi Fukase. Their work appears in journals such as Proceedings of the National Academy of Sciences, Journal of Biological Chemistry and The Journal of Experimental Medicine.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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