H. C. J. OTTENHEIJM

3.7k citations

121 papers · 2.9k indexed · h-index 28

Co-authors: Pedro H. H. Hermkens David C. Rees Ralf Plate Jacobus D. M. Herscheid R. J. F. Nivard Rob M. J. Liskamp Susan E. Booth Jos F.M. Smits
Topics: Chemical Synthesis and Analysis (44 papers)Synthesis and Biological Evaluation (19 papers)Cancer therapeutics and mechanisms (15 papers)
Cited by: Organic Chemistry Molecular Biology Pharmacology
Journals: Chemical Reviews Proceedings of the National Academy of Sciences Journal of the American Chemical Society
Partner nations: Netherlands Spain Italy

In The Last Decade

H. C. J. OTTENHEIJM

119 papers receiving 2.7k citations

Peers

Countries citing papers authored by H. C. J. OTTENHEIJM

Since Specialization

Citations

This map shows the geographic impact of H. C. J. OTTENHEIJM's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by H. C. J. OTTENHEIJM with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites H. C. J. OTTENHEIJM more than expected).

Fields of papers citing papers by H. C. J. OTTENHEIJM

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by H. C. J. OTTENHEIJM. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by H. C. J. OTTENHEIJM. The network helps show where H. C. J. OTTENHEIJM may publish in the future.

Co-authorship network of co-authors of H. C. J. OTTENHEIJM

This figure shows the co-authorship network connecting the top 25 collaborators of H. C. J. OTTENHEIJM. A scholar is included among the top collaborators of H. C. J. OTTENHEIJM based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with H. C. J. OTTENHEIJM. H. C. J. OTTENHEIJM is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Application of a ligand‐based theoretical approach to derive conversion paths and ligand conformations in CYP11B2‐mediated aldosterone formation 2011 ·Journal of Computational Chemistry ·Luc Roumen,(unknown),K. Pieterse,P.A.J. Hilbers,(unknown),Ralf Plate,(unknown),(unknown),Judith M. A. Emmen,Dirk Leysen,Jos F.M. Smits,H. C. J. OTTENHEIJM,J. J. Rob Hermans	2
2	Wnt/frizzled signalling modulates the migration and differentiation of immortalized cardiac fibroblasts 2010 ·Cardiovascular Research ·Hilde Laeremans,Sander S. Rensen,H. C. J. OTTENHEIJM,Jos F.M. Smits,W. Matthijs Blankesteijn	56
3	Construction of 3D models of the CYP11B family as a tool to predict ligand binding characteristics 2007 ·Journal of Computer-Aided Molecular Design ·Luc Roumen,Marijn P. A. Sanders,K. Pieterse,P.A.J. Hilbers,Ralf Plate,(unknown),(unknown),Jos F.M. Smits,(unknown),Judith M. A. Emmen,H. C. J. OTTENHEIJM,Dirk Leysen,J. J. Rob Hermans	47
4	ChemInform Abstract: 5‐HT2 Antagonists: A Concept for the Treatment of Schizophrenia 1997 ·ChemInform ·Dirk Leysen,Joannes T. M. Linders,H. C. J. OTTENHEIJM	2
5	Sparsomycin and its analogues: a new approach for evaluating their potency as inhibitors of peptide bond formation. 1996 ·Molecular Pharmacology ·(unknown),Dennis Synetos,H. C. J. OTTENHEIJM,L.A.M. van den Broek,C. Coutsogeorgopoulos	2
6	Peptide-derived transition state analogue inhibitors of thrombin; Synthesis, activity and selectivity 1995 ·Bioorganic & Medicinal Chemistry ·(unknown),(unknown),Arie Visser,Peter D. J. Grootenhuis,J. W. VAN NISPEN,H. C. J. OTTENHEIJM	10
7	Antitumour activity and retinotoxicity of ethyldeshydroxy-sparsomycin in mice 1995 ·European Journal of Cancer ·(unknown),D. J. Theo Wagener,D. De Vos,H. C. J. OTTENHEIJM,H.J. Winkens,(unknown),W.J. De Grip	2
8	Concentration and sequence dependent synergism of ethyldeshydroxy-sparsomycin in combination with antitumor agents 1994 ·Anti-Cancer Drugs ·(unknown),D. J. Theo Wagener,(unknown),(unknown),H. C. J. OTTENHEIJM,W.J. De Grip	4
9	Correlation of the in vitro cytotoxicity of ethyldeshydroxysparsomycin and cisplatin with the in vivo antitumour activity in murine L1210 leukaemia and two resistant L1210 sublcones 1993 ·Cancer Chemotherapy and Pharmacology ·(unknown),D. J. Theo Wagener,(unknown),(unknown),(unknown),Leon A. G. M. van den Broek,H. C. J. OTTENHEIJM	1
10	Biochemical and kinetic characteristics of the interaction of the antitumor antibiotic sparsomycin with prokaryotic and eukaryotic ribosomes 1991 ·Biochemistry ·Ester Lázaro,(unknown),Ana San‐Félix,H. C. J. OTTENHEIJM,Juan P. G. Ballesta	25
11	Chemical, biochemical and genetic endeavours characterizing the interaction of sparsomycin with the ribosome 1991 ·Biochimie ·Ester Lázaro,Leon A. G. M. van den Broek,(unknown),H. C. J. OTTENHEIJM,Juan P. G. Ballesta	10
12	Pharmacokinetics of the antitumor antibiotic n-pentyl-sparsomycin in beagle dogs 1990 ·Investigational New Drugs ·Zbigniew Żylicz,D. J. Theo Wagener,(unknown),Tom B. Vree,Eppo van der Kleijn,Leon A. G. M. van den Broek,H. C. J. OTTENHEIJM	9
13	Novel Sulfated Polysaccharides: Dissociation of Anti-Human Immunodeficiency Virus Activity from Antithrombin Activity 1990 ·The Journal of Infectious Diseases ·Masaya Baba,Erik De Clercq,Dominique Schols,Rudi Pauwels,Robert Snoeck,(unknown),G. Van Dedem,(unknown),Paul M.J. Hobbelen,H. C. J. OTTENHEIJM,Frank den Hollander	64
14	Lipophilic analogs of sparsomycin as strong inhibitors of protein synthesis and tumor growth: a structure-activity relationship study 1989 ·Journal of Medicinal Chemistry ·Leon A. G. M. van den Broek,Ester Lázaro,Zbigniew Żylicz,(unknown),(unknown),P. Lelieveld,(unknown),D. J. Theo Wagener,Juan P. G. Ballesta,H. C. J. OTTENHEIJM	30
15	Crystal and molecular structure of 2-(7-cyanonorcaran-7-yl)-5-(ethoxycarbonyl)-4,5,6,11b-tetrahydro(?4-1,2,4-oxadiazolino)-[2,3-a]-?-carboline, C23H24N4O3 1988 ·Journal of Chemical Crystallography ·J. M. M. Smits,Paul T. Beurskens,J.R.M. Smits,Ralf Plate,H. C. J. OTTENHEIJM	8
16	The development of sparsomycin as an anti-tumour drug. 1988 ·PubMed ·H. C. J. OTTENHEIJM,Leon A. G. M. van den Broek	4
17	Pharmacokinetics and toxicology of sparsomycin in beagle dogs 1987 ·Cancer Chemotherapy and Pharmacology ·Zbigniew Żylicz,D. J. Theo Wagener,(unknown),(unknown),(unknown),Benjamin Winograd,Eppo van der Kleijn,Tom B. Vree,(unknown),Leon A. G. M. van den Broek,H. C. J. OTTENHEIJM	4
18	6 Chemical and Biological Aspects of Sparsomycin, an Antibiotic, from Streptomyces 1986 ·Progress in medicinal chemistry ·H. C. J. OTTENHEIJM,Leon A. G. M. van den Broek,Juan P. G. Ballesta,Zbigniew Żylicz	24
19	Crystal and molecular structure of (exo)-2-methoxycarbonyl-5-ethoxycarbonyl-4,5,6,11b-tetrahydroisoxazolidino-[2,3-a]-?-carboline, C18H20N2O5 1986 ·Journal of Chemical Crystallography ·J.M.M. Smits,Paul T. Beurskens,Ralf Plate,H. C. J. OTTENHEIJM	4
20	Approaches to the antibiotic sparsomycin. An efficient synthesis of the cysteinol mono-oxodithioacetal moiety 1978 ·Tetrahedron Letters ·H. C. J. OTTENHEIJM,Rob M. J. Liskamp	5

About H. C. J. OTTENHEIJM

H. C. J. OTTENHEIJM is a scholar working on Organic Chemistry, Molecular Biology and Toxicology, having authored 121 papers that have together received 2.9k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (44 papers), Synthesis and Biological Evaluation (19 papers) and Cancer therapeutics and mechanisms (15 papers). The work is most often cited by research in Organic Chemistry (1.9k citations), Molecular Biology (1.9k citations) and Pharmacology (249 citations). H. C. J. OTTENHEIJM has collaborated with scholars based in Netherlands, Spain and Italy. Frequent co-authors include Pedro H. H. Hermkens, David C. Rees, Ralf Plate, Jacobus D. M. Herscheid, R. J. F. Nivard, Rob M. J. Liskamp, Susan E. Booth, Jos F.M. Smits, Leon A. G. M. van den Broek and W. Matthijs Blankesteijn. Their work appears in journals such as Chemical Reviews, Proceedings of the National Academy of Sciences and Journal of the American Chemical Society.

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