Gary L. Grunewald

2.4k citations

119 papers · 2.0k indexed · h-index 24

Co-authors: Kevin R. Criscione Howard E. Zimmerman Vilas H. Dahanukar Michael J. McLeish Daniel J. Sall Jennifer L. Martin Ronald T. Borchardt Gunda I. Georg
Topics: Synthesis and Biological Activity (56 papers)Chemical Synthesis and Analysis (37 papers)Berberine and alkaloids research (18 papers)
Cited by: Organic Chemistry Pharmaceutical Science Cancer Research
Journals: Journal of the American Chemical Society Biochemistry Analytical Biochemistry
Partner nations: United States Australia New Zealand

In The Last Decade

Gary L. Grunewald

117 papers receiving 1.9k citations

Peers

Countries citing papers authored by Gary L. Grunewald

Since Specialization

Citations

This map shows the geographic impact of Gary L. Grunewald's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Gary L. Grunewald with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Gary L. Grunewald more than expected).

Fields of papers citing papers by Gary L. Grunewald

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Gary L. Grunewald. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Gary L. Grunewald. The network helps show where Gary L. Grunewald may publish in the future.

Co-authorship network of co-authors of Gary L. Grunewald

This figure shows the co-authorship network connecting the top 25 collaborators of Gary L. Grunewald. A scholar is included among the top collaborators of Gary L. Grunewald based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Gary L. Grunewald. Gary L. Grunewald is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Time-dependent inactivation of human phenylethanolamine N-methyltransferase by 7-isothiocyanatotetrahydroisoquinoline 2009 ·Bioorganic & Medicinal Chemistry Letters ·Qian Wu,Joanne M. Caine,Stuart Thomson,(unknown),Gary L. Grunewald,Michael J. McLeish	2
2	Exploring the active site of phenylethanolamine N-methyltransferase with 1,2,3,4-tetrahydrobenz[h]isoquinoline inhibitors 2006 ·Bioorganic & Medicinal Chemistry ·Gary L. Grunewald,(unknown),(unknown),Kevin R. Criscione	9
3	Disulfide-linked dimers of human adrenaline synthesizing enzyme PNMT are catalytically active 2005 ·Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics ·Christine L. Gee,Amanda Nourse,(unknown),Qian Wu,Joel D. A. Tyndall,Gary L. Grunewald,Michael J. McLeish,Jennifer L. Martin	4
4	Exploring the active site of phenylethanolamine N-methyltransferase with 3-hydroxyethyl- and 3-hydroxypropyl-7-substituted-1,2,3,4-tetrahydroisoquinolines 2004 ·Bioorganic & Medicinal Chemistry Letters ·Gary L. Grunewald,F. Anthony Romero,(unknown),Kevin R. Criscione,Jean D. Deupree,(unknown),David B. Bylund	5
5	Phenylethanolamine N-methyltransferase inhibition: re-evaluation of kinetic data 2004 ·Bioorganic & Medicinal Chemistry Letters ·Qian Wu,Kevin R. Criscione,Gary L. Grunewald,Michael J. McLeish	11
6	Effects of a 3-Alkyl-, 4-Hydroxy- and/or 8-Aromatic-substituent on the Phenylethanolamine N-Methyltransferase Inhibitor Potency and α2-Adrenoceptor Affinity of 2,3,4,5-Tetrahydro-1H-2-benzazepines 2001 ·Bioorganic & Medicinal Chemistry ·Gary L. Grunewald,Vilas H. Dahanukar,Kevin R. Criscione	18
7	Getting the Adrenaline Going 2001 ·Structure ·Jennifer L. Martin,Jakob Begun,Michael J. McLeish,Joanne M. Caine,Gary L. Grunewald	53
8	Comparative molecular field analysis (CoMFA) models of phenylethanolamine N-methyltransferase (PNMT) and the α2-adrenoceptor: The development of new, highly selective inhibitors of PNMT 1999 ·Bioorganic & Medicinal Chemistry Letters ·Gary L. Grunewald,Timothy M. Caldwell,Vilas H. Dahanukar,(unknown),Kevin R. Criscione	14
9	1,3-Dimethyl-7-substituted-1,2,3,4-tetrahydroisoquinolines as probes for the binding orientation of tetrahydroisoquinoline at the active site of phenylethanolamine N-methyltransferase[1] 1999 ·Bioorganic & Medicinal Chemistry ·Gary L. Grunewald,Timothy M. Caldwell,Qifang Li,Kevin R. Criscione	10
10	The oxetane conformational lock of paclitaxel: Structural analysis of D-secopaclitaxel 1999 ·Bioorganic & Medicinal Chemistry Letters ·Thomas C. Boge,Michael Hepperle,David G. Vander Velde,(unknown),Gary L. Grunewald,Gunda I. Georg	18
11	Recombinant Human PhenylethanolamineN-Methyltransferase: Overproduction inEscherichia coli,Purification, and Characterization 1996 ·Protein Expression and Purification ·Joanne M. Caine,Ian Macreadie,Gary L. Grunewald,Michael J. McLeish	21
12	Influence of stereochemical factors on the partition-coefficient of diastereoisomers in a biphasic octan-1-Ol water-system 1993 ·Archive ouverte UNIGE (University of Geneva) ·Ruey‐Shiuan Tsai,Pierre‐Alain Carrupt,Bernard Testa,Nabil El Tayar,Gary L. Grunewald,A. F. Casy	3
13	Homoallylic amines related to zimeldine. Comparative study on neuronal serotonin and norepinephrine reuptake based on conformational analysis 1988 ·Journal of Medicinal Chemistry ·Thomas Högberg,Svante B. Ross,Patrik Ström,Gary L. Grunewald,(unknown),Jeffrey D. Bunce	13
14	Conformational preference for the binding of biaryl substrates and inhibitors to the active site of phenylethanolamine N-methyltransferase (PNMT) 1988 ·Journal of Medicinal Chemistry ·Gary L. Grunewald,(unknown),Daniel J. Sall,James A. Monn	7
15	Conformationally defined adrenergic agents. 13. Conformational and steric aspects of the inhibition of phenylethanolamine N-methyltransferase by benzylamines 1988 ·Journal of Medicinal Chemistry ·Gary L. Grunewald,Daniel J. Sall,James A. Monn	23
16	Anticonvulsant activities of phenyl-substituted bicyclic 2,4-oxazolidinediones and monocyclic models. Comparison with binding to the neuronal voltage-dependent sodium channel 1988 ·Journal of Medicinal Chemistry ·Wayne J. Brouillette,George Bosworth Brown,Timothy M. DeLorey,Shyam Shirali,Gary L. Grunewald	16
17	Conformationally defined adrenergic agents. 10. Binding orientation of amphetamine and norfenfluramine analogs in the benzonorbornene and benzobicyclo[3.2.1]octane ring systems at the active site of phenylethanolamine N-methyltransferase (PNMT) 1987 ·Journal of Medicinal Chemistry ·Gary L. Grunewald,(unknown),Daniel J. Sall	12
18	Inhibition of phenylethanolamine N-methyltransferase (PNMT) by aromatic hydroxy-substituted 1,2,3,4-tetrahydroisoquinolines. Further studies on the hydrophilic pocket of the aromatic ring binding region of the active site 1987 ·Journal of Medicinal Chemistry ·Daniel J. Sall,Gary L. Grunewald	26
19	Conformationally defined adrenergic agents. III. The importance of compartmentation in the release of norepinephrine from rat atria by endo- and exo-2-methylaminobenzobicyclo-[2.2.2]octene, conformationally defined analogs of methamphetamine. 1978 ·Journal of Pharmacology and Experimental Therapeutics ·James A. Ruth,Gary L. Grunewald,Charles O. Rutledge	9
20	2,3-ジクロロ-5,6-ジシアノベンゾキノン(DDQ)の相当するヒドロキノン(DDHQ)からの再生のための速く,簡便で,高収率な方法 1976 ·(unknown),Gary L. Grunewald	2

About Gary L. Grunewald

Gary L. Grunewald is a scholar working on Cancer Research, Organic Chemistry and Biochemistry, having authored 119 papers that have together received 2.0k indexed citations. Recurring topics across this work include Synthesis and Biological Activity (56 papers), Chemical Synthesis and Analysis (37 papers) and Berberine and alkaloids research (18 papers). The work is most often cited by research in Organic Chemistry (1.1k citations), Pharmaceutical Science (212 citations) and Cancer Research (394 citations). Gary L. Grunewald has collaborated with scholars based in United States, Australia and New Zealand. Frequent co-authors include Kevin R. Criscione, Howard E. Zimmerman, Vilas H. Dahanukar, Michael J. McLeish, Daniel J. Sall, Jennifer L. Martin, Ronald T. Borchardt, Gunda I. Georg, Timothy M. Caldwell and David G. Vander Velde. Their work appears in journals such as Journal of the American Chemical Society, Biochemistry and Analytical Biochemistry.

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