Lawrence I. Kruse

2.7k citations

68 papers · 2.1k indexed · 2 hit papers · h-index 26

Co-authors: Jack E. Baldwin Richard C. Thomas Roland E. Dolle Walter E. DeWolf William Dupont Christopher Southan Stanley J. Schmidt Paula J. Goodhart
Topics: Chemical Synthesis and Analysis (6 papers)DNA and Nucleic Acid Chemistry (5 papers)Chemical Reaction Mechanisms (5 papers)
Cited by: Organic Chemistry Pharmaceutical Science Biochemistry
Journals: Journal of the American Chemical Society Journal of Biological Chemistry Biochemistry
Partner nations: United States United Kingdom Russia

In The Last Decade

Lawrence I. Kruse

67 papers receiving 2.0k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

5-Endo-trigonal reactions: a disfavoured ring closure

1976 358 citations Jack E. Baldwin, Lawrence I. Kruse et al. Journal of the Chemical Society Chemical Communications profile →
Rules for ring closure: ring formation by conjugate addition of oxygen nucleophiles

1977 302 citations Jack E. Baldwin, Richard C. Thomas et al. The Journal of Organic Chemistry profile →

Peers

Countries citing papers authored by Lawrence I. Kruse

Since Specialization

Citations

This map shows the geographic impact of Lawrence I. Kruse's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence I. Kruse with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence I. Kruse more than expected).

Fields of papers citing papers by Lawrence I. Kruse

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence I. Kruse. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence I. Kruse. The network helps show where Lawrence I. Kruse may publish in the future.

Co-authorship network of co-authors of Lawrence I. Kruse

This figure shows the co-authorship network connecting the top 25 collaborators of Lawrence I. Kruse. A scholar is included among the top collaborators of Lawrence I. Kruse based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Lawrence I. Kruse. Lawrence I. Kruse is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Potent agonists of the Hedgehog signaling pathway 2009 ·Bioorganic & Medicinal Chemistry Letters ·Shirley A. Brunton,J. H. A. STIBBARD,Lee L. Rubin,Oivin Guicherit,Lawrence I. Kruse,S. Russ Price,Raffaella Di Lucrezia,Colin H. MacKinnon,(unknown),(unknown),(unknown),(unknown)	19
2	Synthesis of Novel Thiol-Containing Citric Acid Analogs. Kinetic Evaluation of These and Other Potential Active-Site-Directed and Mechanism-Based Inhibitors of ATP Citrate Lyase 1995 ·Journal of Medicinal Chemistry ·Roland E. Dolle,(unknown),(unknown),Lawrence I. Kruse,Drake S. Eggleston,Barbara Saxty,Timothy N. C. Wells,Pieter H.E. Groot	15
3	Achiral internucleoside linkages 2: O-CH2-CH2 linkage 1994 ·Bioorganic & Medicinal Chemistry Letters ·Thomas J. Caulfield,C. V. C. Prasad,(unknown),Catherine Prouty,Ashis Saha,Donald A. Upson,Lawrence I. Kruse	6
4	Achiral internucleoside linkages: CH2-CH2-NH and nH-CH2-CH2 linkages 1993 ·Bioorganic & Medicinal Chemistry Letters ·Thomas J. Caulfield,C. V. C. Prasad,Catherine Prouty,Ashis Saha,(unknown),(unknown),(unknown),Donald A. Upson,Lawrence I. Kruse	17
5	Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans .DELTA.24-sterol methyltransferase 1992 ·Journal of Medicinal Chemistry ·Mark A. Ator,Stanley J. Schmidt,Jerry L. Adams,Roland E. Dolle,Lawrence I. Kruse,(unknown),(unknown)	39
6	ATP-citrate-lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-.beta.-lactam containing analogs of citric acid as potential tight-binding inhibitors 1992 ·Journal of Medicinal Chemistry ·Roland E. Dolle,(unknown),(unknown),Lawrence I. Kruse,(unknown),Barbara Saxty,Timothy N. C. Wells,Pieter H.E. Groot	14
7	Design and synthesis of 14.alpha.-methyl-15-aza-D-homosterols as novel antimycotics 1990 ·Journal of Medicinal Chemistry ·Roland E. Dolle,H.S. Allaudeen,Lawrence I. Kruse	30
8	Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine .beta.-hydroxylase. 4. Structure-activity relationships at the copper binding site 1990 ·Journal of Medicinal Chemistry ·Lawrence I. Kruse,Carl Kaiser,Walter E. DeWolf,Joseph A. Finkelstein,James S. Frazee,(unknown),Stephen T. Ross,Kathryn E. Flaim,John L. Sawyer	42
9	Inactivation of dopamine β-hydroxylase by p-cresol: Evidence for a second, minor site of covalent modification at tyrosine 357 1990 ·Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Christopher Southan,Walter E. DeWolf,Lawrence I. Kruse	19
10	Inactivation of dopamine .beta.-hydroxylase by .beta.-ethynyltyramine: kinetic characterization and covalent modification of an active site peptide 1989 ·Biochemistry ·Walter E. DeWolf,Pamela A. Chambers,Christopher Southan,David Saunders,Lawrence I. Kruse	20
11	Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs 1989 ·Journal of Medicinal Chemistry ·Lawrence I. Kruse,David L. Ladd,(unknown),Francis L. McCabe,Shau Ming Mong,Leo F. Faucette,Randall S. Johnson	40
12	Synthesis of zymosterol, fecosterol, and related biosynthetic sterol intermediates 1989 ·Journal of the American Chemical Society ·Roland E. Dolle,Stanley J. Schmidt,Karl F. Erhard,Lawrence I. Kruse	29
13	Effects of the novel dopamine beta-hydroxylase inhibitor SK&F 102698 on catecholamines and blood pressure in spontaneously hypertensive rats. 1988 ·Journal of Pharmacology and Experimental Therapeutics ·Barry A. Berkowitz,Anthony J. Arleth,C P Sung,Lawrence I. Kruse,Walter E. DeWolf,(unknown)	1
14	Inactivation of dopamine .beta.-hydroxylase by p-cresol: isolation and characterization of covalently modified active site peptides 1988 ·Biochemistry ·Walter E. DeWolf,Steven A. Carr,Angela Varrichio,Paula J. Goodhart,(unknown),Gerald D. Roberts,Christopher Southan,Roland E. Dolle,Lawrence I. Kruse	55
15	.beta.-Substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine .beta.-hydroxylase 1988 ·Journal of Medicinal Chemistry ·Lawrence I. Kruse,Carl Kaiser,Walter E. DeWolf,Pamela A. Chambers,Paula J. Goodhart,(unknown),Eliot H. Ohlstein	28
16	Palladium catalysed alkoxycarbonylation of phenols to benzoate esters 1987 ·Journal of the Chemical Society Chemical Communications ·Roland E. Dolle,Stanley J. Schmidt,Lawrence I. Kruse	86
17	Study of aromatic functional group conformations in solution by nuclear Overhauser enhancement and relaxation techniques: detection of .pi.-electron density and correlation with chemical reactivity 1985 ·Journal of the American Chemical Society ·Lawrence I. Kruse,Charles DeBrosse,(unknown)	28
18	Rules for ring closure. Stereoelectronic control in the endocyclic alkylation of ketone enolates 1977 ·Journal of the Chemical Society Chemical Communications ·Jack E. Baldwin,Lawrence I. Kruse	108
19	Rules for ring closure: ring formation by conjugate addition of oxygen nucleophilesbreakdown → 1977 ·The Journal of Organic Chemistry ·Jack E. Baldwin,Richard C. Thomas,Lawrence I. Kruse,(unknown)	302
20	Stereospecific synthesis of penicillins. Conversion from a peptide precursor 1976 ·Journal of the American Chemical Society ·Jack E. Baldwin,Michael Christie,Stephen B. Haber,Lawrence I. Kruse	23

About Lawrence I. Kruse

Lawrence I. Kruse is a scholar working on Biochemistry, Organic Chemistry and Pharmacology, having authored 68 papers that have together received 2.1k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), DNA and Nucleic Acid Chemistry (5 papers) and Chemical Reaction Mechanisms (5 papers). The work is most often cited by research in Organic Chemistry (1.3k citations), Pharmaceutical Science (116 citations) and Biochemistry (125 citations). Lawrence I. Kruse has collaborated with scholars based in United States, United Kingdom and Russia. Frequent co-authors include Jack E. Baldwin, Richard C. Thomas, Roland E. Dolle, Walter E. DeWolf, William Dupont, Christopher Southan, Stanley J. Schmidt, Paula J. Goodhart, Michael D. Meyer and Carl Kaiser. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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