Lawrence I. Kruse

2.7k citations

68 papers · 2.1k indexed · 2 hit papers · h-index 26

Organic Chemistry top 1%
- Chemical Reaction Mechanisms 5
- Organic Chemistry Cycloaddition Reactions 5
- Synthesis and Characterization of Heterocyclic Compounds 4
Pharmaceutical Science top 5%
Biochemistry top 5%
- Biochemical Acid Research Studies 5
Inorganic Chemistry top 10%
Molecular Biology top 10%
- Chemical Synthesis and Analysis 6
- DNA and Nucleic Acid Chemistry 5
- Steroid Chemistry and Biochemistry 5
Physiology
- Diet and metabolism studies 4

Co-authors: Jack E. Baldwin Richard C. Thomas Roland E. Dolle Walter E. DeWolf William Dupont Christopher Southan Stanley J. Schmidt Paula J. Goodhart
Cited by: Organic Chemistry Pharmaceutical Science Biochemistry
Journals: Journal of the American Chemical Society (4 papers)Journal of Biological Chemistry (1 paper)Biochemistry (6 papers)
Partner nations: United States United Kingdom Russia

In The Last Decade

Lawrence I. Kruse

67 papers receiving 2.0k citations

Hit Papers

align trajectories log scale

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

1977 The Journal of Organic Chemistry
1976 Journal of the Chemical Society Chemical Communications

Peers

Countries citing papers authored by Lawrence I. Kruse

Since Specialization

Citations

This map shows the geographic impact of Lawrence I. Kruse's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Lawrence I. Kruse with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Lawrence I. Kruse more than expected).

Fields of papers citing papers by Lawrence I. Kruse

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Lawrence I. Kruse. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Lawrence I. Kruse. The network helps show where Lawrence I. Kruse may publish in the future.

Co-authorship network

The 25 scholars most cited alongside Lawrence I. Kruse, linked wherever they have co-authored with each other. Click a name or a connecting line to browse the papers they share.

Border = papers with Lawrence I. Kruse Line = papers co-authored together Lawrence I. Kruse links everyone, so they are left out of the graph.

All Works

Sort: Min cites: Since: Top N: Style:

20 of 20 papers shown

#	Work
1	Potent agonists of the Hedgehog signaling pathway Bioorganic & Medicinal Chemistry Letters ·Shirley A. Brunton,J. H. A. STIBBARD,Lee L. Rubin,Oivin Guicherit,Lawrence I. Kruse,S. Russ Price,Raffaella Di Lucrezia,Colin H. MacKinnon,Alaric Avery,Yvonne Park,Danielle Buxton,Edward A. Boyd	2009	19
2	Synthesis of Novel Thiol-Containing Citric Acid Analogs. Kinetic Evaluation of These and Other Potential Active-Site-Directed and Mechanism-Based Inhibitors of ATP Citrate Lyase Journal of Medicinal Chemistry ·Roland E. Dolle,Andy Gribble,T Wilkes,Lawrence I. Kruse,Drake S. Eggleston,Barbara Saxty,Timothy N. C. Wells,Pieter H.E. Groot	1995	15
3	Achiral internucleoside linkages 2: O-CH2-CH2 linkage Bioorganic & Medicinal Chemistry Letters ·Thomas J. Caulfield,C. V. C. Prasad,Daniel Delecki,Catherine Prouty,Ashis Saha,Donald A. Upson,Lawrence I. Kruse	1994	6
4	Achiral internucleoside linkages: CH2-CH2-NH and nH-CH2-CH2 linkages Bioorganic & Medicinal Chemistry Letters ·Thomas J. Caulfield,C. V. C. Prasad,Catherine Prouty,Ashis Saha,Mark Sardaro,Wayne C. Schairer,Anne M. Yawman,Donald A. Upson,Lawrence I. Kruse	1993	17
5	Synthesis, specificity, and antifungal activity of inhibitors of the Candida albicans .DELTA.24-sterol methyltransferase Journal of Medicinal Chemistry ·Mark A. Ator,Stanley J. Schmidt,Jerry L. Adams,Roland E. Dolle,Lawrence I. Kruse,Carrie L. Frey,Janice M. Barone	1992	39
6	ATP-citrate-lyase as a target for hypolipidemic intervention. Sulfoximine and 3-hydroxy-.beta.-lactam containing analogs of citric acid as potential tight-binding inhibitors Journal of Medicinal Chemistry ·Roland E. Dolle,David McNair,Mark J. Hughes,Lawrence I. Kruse,Drake Eggelston,Barbara Saxty,Timothy N. C. Wells,Pieter H.E. Groot	1992	14
7	Design and synthesis of 14.alpha.-methyl-15-aza-D-homosterols as novel antimycotics Journal of Medicinal Chemistry ·Roland E. Dolle,H.S. Allaudeen,Lawrence I. Kruse	1990	30
8	Some benzyl-substituted imidazoles, triazoles, tetrazoles, pyridinethiones, and structural relatives as multisubstrate inhibitors of dopamine .beta.-hydroxylase. 4. Structure-activity relationships at the copper binding site Journal of Medicinal Chemistry ·Lawrence I. Kruse,Carl Kaiser,Walter E. DeWolf,Joseph A. Finkelstein,James S. Frazee,Eileen L. Hilbert,Stephen T. Ross,Kathryn E. Flaim,John L. Sawyer	1990	42
9	Inactivation of dopamine β-hydroxylase by p-cresol: Evidence for a second, minor site of covalent modification at tyrosine 357 Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology ·Christopher Southan,Walter E. DeWolf,Lawrence I. Kruse	1990	19
10	Inactivation of dopamine .beta.-hydroxylase by .beta.-ethynyltyramine: kinetic characterization and covalent modification of an active site peptide Biochemistry ·Walter E. DeWolf,Pamela A. Chambers,Christopher Southan,David Saunders,Lawrence I. Kruse	1989	20
11	Synthesis, tubulin binding, antineoplastic evaluation, and structure-activity relationship of oncodazole analogs Journal of Medicinal Chemistry ·Lawrence I. Kruse,David L. Ladd,Peter B. Harrsch,Francis L. McCabe,Shau Ming Mong,Leo F. Faucette,Randall S. Johnson	1989	40
12	Synthesis of zymosterol, fecosterol, and related biosynthetic sterol intermediates Journal of the American Chemical Society ·Roland E. Dolle,Stanley J. Schmidt,Karl F. Erhard,Lawrence I. Kruse	1989	29
13	Effects of the novel dopamine beta-hydroxylase inhibitor SK&F 102698 on catecholamines and blood pressure in spontaneously hypertensive rats. Journal of Pharmacology and Experimental Therapeutics ·Barry A. Berkowitz,Anthony J. Arleth,C P Sung,Lawrence I. Kruse,Walter E. DeWolf,E H Ohlstein	1988	1
14	Inactivation of dopamine .beta.-hydroxylase by p-cresol: isolation and characterization of covalently modified active site peptides Biochemistry ·Walter E. DeWolf,Steven A. Carr,Angela Varrichio,Paula J. Goodhart,Mary Mentzer,Gerald D. Roberts,Christopher Southan,Roland E. Dolle,Lawrence I. Kruse	1988	55
15	.beta.-Substituted phenethylamines as high-affinity mechanism-based inhibitors of dopamine .beta.-hydroxylase Journal of Medicinal Chemistry ·Lawrence I. Kruse,Carl Kaiser,Walter E. DeWolf,Pamela A. Chambers,Paula J. Goodhart,Mildred Ezekiel,Eliot H. Ohlstein	1988	28
16	Palladium catalysed alkoxycarbonylation of phenols to benzoate esters Journal of the Chemical Society Chemical Communications ·Roland E. Dolle,Stanley J. Schmidt,Lawrence I. Kruse	1987	86
17	Study of aromatic functional group conformations in solution by nuclear Overhauser enhancement and relaxation techniques: detection of .pi.-electron density and correlation with chemical reactivity Journal of the American Chemical Society ·Lawrence I. Kruse,Charles DeBrosse,Carolyn H. Kruse	1985	28
18	Rules for ring closure. Stereoelectronic control in the endocyclic alkylation of ketone enolates Journal of the Chemical Society Chemical Communications ·Jack E. Baldwin,Lawrence I. Kruse	1977	108
19	Rules for ring closure: ring formation by conjugate addition of oxygen nucleophilesbreakdown → The Journal of Organic Chemistry ·Jack E. Baldwin,Richard C. Thomas,Lawrence I. Kruse,Lee Silberman	1977	302
20	Stereospecific synthesis of penicillins. Conversion from a peptide precursor Journal of the American Chemical Society ·Jack E. Baldwin,Michael Christie,Stephen B. Haber,Lawrence I. Kruse	1976	23

About Lawrence I. Kruse

Lawrence I. Kruse is a scholar working on Biochemistry, Organic Chemistry and Pharmacology, having authored 68 papers that have together received 2.1k indexed citations. Recurring topics across this work include Chemical Synthesis and Analysis (6 papers), DNA and Nucleic Acid Chemistry (5 papers), Chemical Reaction Mechanisms (5 papers), Biochemical Acid Research Studies (5 papers), Organic Chemistry Cycloaddition Reactions (5 papers), Steroid Chemistry and Biochemistry (5 papers), Synthesis and Characterization of Heterocyclic Compounds (4 papers) and Diet and metabolism studies (4 papers). The work is most often cited by research in Organic Chemistry (1.3k citations), Pharmaceutical Science (116 citations) and Biochemistry (125 citations). Lawrence I. Kruse has collaborated with scholars based in United States, United Kingdom and Russia. Frequent co-authors include Jack E. Baldwin, Richard C. Thomas, Roland E. Dolle, Walter E. DeWolf, William Dupont, Christopher Southan, Stanley J. Schmidt, Paula J. Goodhart, Michael D. Meyer and Carl Kaiser. Their work appears in journals such as Journal of the American Chemical Society, Journal of Biological Chemistry and Biochemistry.

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

Explore authors with similar magnitude of impact