Michael Hepperle

1.8k total citations
25 papers, 1.1k citations indexed

About

Michael Hepperle is a scholar working on Oncology, Organic Chemistry and Molecular Biology. According to data from OpenAlex, Michael Hepperle has authored 25 papers receiving a total of 1.1k indexed citations (citations by other indexed papers that have themselves been cited), including 16 papers in Oncology, 11 papers in Organic Chemistry and 8 papers in Molecular Biology. Recurrent topics in Michael Hepperle's work include Cancer Treatment and Pharmacology (13 papers), Synthetic Organic Chemistry Methods (7 papers) and NF-κB Signaling Pathways (6 papers). Michael Hepperle is often cited by papers focused on Cancer Treatment and Pharmacology (13 papers), Synthetic Organic Chemistry Methods (7 papers) and NF-κB Signaling Pathways (6 papers). Michael Hepperle collaborates with scholars based in United States. Michael Hepperle's co-authors include Gunda I. Georg, Yajun Xu, Danyi Wen, Yuhua Nong, Lloyd T. Lam, Lenny Dang, Maria Hottelet, Julian Adams, R. Eric Davis and Louis M. Staudt and has published in prestigious journals such as Blood, Biochemistry and Clinical Cancer Research.

In The Last Decade

Michael Hepperle

25 papers receiving 1.1k citations

Peers

Countries citing papers authored by Michael Hepperle

Since Specialization

Citations

This map shows the geographic impact of Michael Hepperle's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Michael Hepperle with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Michael Hepperle more than expected).

Fields of papers citing papers by Michael Hepperle

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Michael Hepperle. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Michael Hepperle. The network helps show where Michael Hepperle may publish in the future.

Co-authorship network of co-authors of Michael Hepperle

This figure shows the co-authorship network connecting the top 25 collaborators of Michael Hepperle. A scholar is included among the top collaborators of Michael Hepperle based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Michael Hepperle. Michael Hepperle is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

#	Work	Indexed citations
1	Discovery of 5-substituted-N-arylpyridazinones as inhibitors of p38 MAP kinase 2010 ·Bioorganic & Medicinal Chemistry Letters ·(unknown), Michael Hepperle, John K. Walker, Xing Li, Rajesh Devraj, (unknown), (unknown), Shaun R. Selness	7
2	Identification of SD-0006, a potent diaryl pyrazole inhibitor of p38 MAP kinase 2010 ·Bioorganic & Medicinal Chemistry Letters ·John K. Walker, Shaun R. Selness, Rajesh Devraj, Michael Hepperle, Win Naing, H.-S. Shieh, (unknown), (unknown), Daniel L. Flynn, (unknown), Dean Messing, (unknown), (unknown), (unknown), Joseph B. Monahan, Joseph P. Portanova	19
3	Synthesis and antiviral activity of HCV NS3/4A peptidomimetic boronic acid inhibitors 2009 ·Bioorganic & Medicinal Chemistry Letters ·Amogh Boloor, (unknown), (unknown), David T. Winn, (unknown), Marlena Walls, Ping Wei, (unknown), Xiaoli Zhang, Yuliang Zhang, Michael Hepperle, (unknown), David A. Campbell, Juan M. Betancort	12
4	A Selective Small Molecule IκB Kinase β Inhibitor Blocks Nuclear Factor κB-Mediated Inflammatory Responses in Human Fibroblast-Like Synoviocytes, Chondrocytes, and Mast Cells 2006 ·Journal of Pharmacology and Experimental Therapeutics ·Danyi Wen, Yuhua Nong, (unknown), Pranoti Gangurde, (unknown), (unknown), Marie Keaveney, Hong Cheng, Chris Fraser, Lisa Schopf, Michael Hepperle, Geraldine Harriman, Bruce Jaffee, Timothy D. Ocain, Yajun Xu	101
5	Use of molecular imaging to quantify response to IKK‐2 inhibitor treatment in murine arthritis 2006 ·Arthritis & Rheumatism ·Elena S. Izmailova, Nancy Paz, Herlen Alencar, (unknown), Lisa Schopf, Michael Hepperle, Joan H. Lane, Geraldine Harriman, Yajun Xu, Timothy D. Ocain, Ralph Weissleder, Umar Mahmood, Aileen M. Healy, Bruce Jaffee	39
6	IKKβ inhibition protects against bone and cartilage destruction in a rat model of rheumatoid arthritis 2006 ·Arthritis & Rheumatism ·Lisa Schopf, Anneli Savinainen, Karen S. Anderson, (unknown), Michelle DuPont, Matthew J. Silva, Elizabeth Siebert, Sudeep Chandra, (unknown), Pranoti Gangurde, Danyi Wen, Joan H. Lane, Yajun Xu, Michael Hepperle, Geraldine Harriman, Timothy D. Ocain, Bruce Jaffee	69
7	Rapid TNFR1-dependent lymphocyte depletion in vivo with a selective chemical inhibitor of IKKβ 2006 ·Blood ·Kumiko Nagashima, Vito G. Sasseville, Danyi Wen, (unknown), Hua Yang, (unknown), Ethan Grant, Michael Hepperle, (unknown), Bruce Jaffee, (unknown), Yajun Xu, Christopher C. Fraser	63
8	Small molecule inhibitors of IkappaB kinase are selectively toxic for subgroups of diffuse large B-cell lymphoma defined by gene expression profiling. 2005 ·PubMed ·Lloyd T. Lam, R. Eric Davis, (unknown), Michael Hepperle, Yajun Xu, Maria Hottelet, Yuhua Nong, Danyi Wen, Julian Adams, Lenny Dang, Louis M. Staudt	252
9	Small Molecule Inhibitors of IκB Kinase Are Selectively Toxic for Subgroups of Diffuse Large B-Cell Lymphoma Defined by Gene Expression Profiling 2005 ·Clinical Cancer Research ·Lloyd T. Lam, R. Eric Davis, (unknown), Michael Hepperle, Yajun Xu, Maria Hottelet, Yuhua Nong, Danyi Wen, Julian Adams, Lenny Dang, Louis M. Staudt	187
10	The oxetane conformational lock of paclitaxel: Structural analysis of D-secopaclitaxel 1999 ·Bioorganic & Medicinal Chemistry Letters ·Thomas C. Boge, Michael Hepperle, David G. Vander Velde, (unknown), Gary L. Grunewald, Gunda I. Georg	18
11	Protection Against β‐Amyloid Toxicity in Primary Neurons by Paclitaxel (Taxol) 1998 ·Journal of Neurochemistry ·Mary L. Michaelis, (unknown), (unknown), (unknown), (unknown), Michael Hepperle, (unknown), Gunda I. Georg	73
12	Probing the Environment of Tubulin-Bound Paclitaxel Using Fluorescent Paclitaxel Analogues 1997 ·Biochemistry ·Suparna Sengupta, Thomas C. Boge, Yanbin Liu, Michael Hepperle, Gunda I. Georg, Richard H. Himes	22
13	Synthesis, Conformational Analysis, and Biological Evaluation of Heteroaromatic Taxanes 1996 ·The Journal of Organic Chemistry ·Gunda I. Georg, Geraldine Harriman, Michael Hepperle, (unknown), David G. Vander Velde, Richard H. Himes	35
14	Preparation of Phenolic Paclitaxel Metabolites 1996 ·Journal of Medicinal Chemistry ·Haeil Park, Michael Hepperle, Thomas C. Boge, Richard H. Himes, Gunda I. Georg	12
15	Medicinal chemistry of paclitaxel: chemistry, structure-activity relationships and conformational analysis. 1995 ·(unknown), (unknown), (unknown), (unknown), (unknown), Apurba Datta, Michael Hepperle, (unknown), (unknown), Lalith Jayasinghe	4
16	Selective Deesterification Studies on Taxanes: Simple and Efficient Hydrazinolysis of C-10 and C-13 Ester Functionalities 1995 ·The Journal of Organic Chemistry ·Apurba Datta, Michael Hepperle, Gunda I. Georg	19
17	Synthesis of 2-O-heteroaroyl taxanes: evaluation of microtubule assembly promotion and cytotoxicity 1995 ·Bioorganic & Medicinal Chemistry Letters ·Gunda I. Georg, Geraldine Harriman, Syed Mashhood Ali, Apurba Datta, Michael Hepperle, Richard H. Himes	11
18	Topliss approach to the synthesis of biologically active substituted N-benzoyl taxol analogues 1994 ·Bioorganic & Medicinal Chemistry Letters ·Gunda I. Georg, Thomas C. Boge, Zacharia S. Cheruvallath, Geraldine Harriman, Michael Hepperle, Haeil Park, Richard H. Himes	11
19	Synthesis and biology of substituted 3′-phenyl taxol analogues 1994 ·Bioorganic & Medicinal Chemistry Letters ·Gunda I. Georg, Zacharia S. Cheruvallath, (unknown), Michael Hepperle, Haeil Park, Richard H. Himes	10
20	Schotten-Baumann acylation of N-debenzoyltaxol; an efficient route to N-acyl taxol analogues and their biological evaluation 1994 ·Bioorganic & Medicinal Chemistry Letters ·Gunda I. Georg, Thomas C. Boge, Zacharia S. Cheruvallath, Geraldine Harriman, Michael Hepperle, Haeil Park, Richard H. Himes	36

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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