Willem P.C. Stemmer

9.2k total citations · 4 hit papers
49 papers, 7.0k citations indexed

About

Willem P.C. Stemmer is a scholar working on Molecular Biology, Genetics and Radiology, Nuclear Medicine and Imaging. According to data from OpenAlex, Willem P.C. Stemmer has authored 49 papers receiving a total of 7.0k indexed citations (citations by other indexed papers that have themselves been cited), including 37 papers in Molecular Biology, 9 papers in Genetics and 8 papers in Radiology, Nuclear Medicine and Imaging. Recurrent topics in Willem P.C. Stemmer's work include CRISPR and Genetic Engineering (11 papers), Enzyme Catalysis and Immobilization (8 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Willem P.C. Stemmer is often cited by papers focused on CRISPR and Genetic Engineering (11 papers), Enzyme Catalysis and Immobilization (8 papers) and Monoclonal and Polyclonal Antibodies Research (8 papers). Willem P.C. Stemmer collaborates with scholars based in United States, Netherlands and Switzerland. Willem P.C. Stemmer's co-authors include Andreas Crameri, Erik A. Whitehorn, Emily Tate, Glenn Dawes, Kim Perry, Stephen B. del Cardayré, Thomas M. Brennan, Herbert L. Heyneker, Keith A. Powell and Joost A. Kolkman and has published in prestigious journals such as Nature, Proceedings of the National Academy of Sciences and Nucleic Acids Research.

In The Last Decade

Willem P.C. Stemmer

49 papers receiving 6.7k citations

Hit Papers

align trajectories

What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

Rapid evolution of a protein in vitro by DNA shuffling

1994 1.4k citations Willem P.C. Stemmer Nature profile →
Improved Green Fluorescent Protein by Molecular Evolution Using DNA Shuffling

1996 993 citations Andreas Crameri, Willem P.C. Stemmer et al. Nature Biotechnology profile →
DNA shuffling of a family of genes from diverse species accelerates directed evolution

1998 603 citations Andreas Crameri, Willem P.C. Stemmer et al. Nature profile →
Single-step assembly of a gene and entire plasmid from large numbers of oligodeoxyribonucleotides

1995 558 citations Willem P.C. Stemmer, Andreas Crameri et al. Gene profile →

Peers — A (Enhanced Table)

Peers by citation overlap · career bar shows stage (early→late) cites · hero ref

Name	h						Papers	Cites
Willem P.C. Stemmer United States	30	5.8k	1.3k	919	912	838	49	7.0k
James R. Swartz United States	53	5.6k 1.0×	1.2k 0.9×	731 0.8×	1.3k 1.4×	729 0.9×	124	7.6k
Michael C. Jewett United States	61	10.3k 1.8×	1.6k 1.3×	928 1.0×	1.2k 1.3×	1.7k 2.1×	214	11.5k
Pedro M. Alzari France	61	7.6k 1.3×	1.2k 0.9×	1.1k 1.2×	1.8k 1.9×	798 1.0×	213	11.3k
William J. Dower United States	25	6.2k 1.1×	1.1k 0.8×	668 0.7×	2.3k 2.5×	641 0.8×	41	8.5k
Harald Kolmar Germany	44	4.5k 0.8×	400 0.3×	648 0.7×	2.3k 2.5×	653 0.8×	249	6.4k
Jeremy Minshull United States	36	5.5k 1.0×	866 0.7×	477 0.5×	248 0.3×	493 0.6×	51	6.6k
Andreas Crameri United States	17	2.7k 0.5×	592 0.5×	457 0.5×	363 0.4×	229 0.3×	19	3.3k
Ario de Marco Slovenia	36	3.5k 0.6×	477 0.4×	438 0.5×	1.4k 1.5×	401 0.5×	138	4.6k
David S. Waugh United States	48	5.8k 1.0×	1.8k 1.4×	397 0.4×	1.0k 1.1×	125 0.1×	140	7.7k
Sarel J. Fleishman Israel	40	4.6k 0.8×	538 0.4×	362 0.4×	1.1k 1.2×	292 0.3×	112	5.7k

Countries citing papers authored by Willem P.C. Stemmer

Since Specialization

Citations

This map shows the geographic impact of Willem P.C. Stemmer's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Willem P.C. Stemmer with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Willem P.C. Stemmer more than expected).

Fields of papers citing papers by Willem P.C. Stemmer

Since Specialization

Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Willem P.C. Stemmer. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Willem P.C. Stemmer. The network helps show where Willem P.C. Stemmer may publish in the future.

Co-authorship network of co-authors of Willem P.C. Stemmer

This figure shows the co-authorship network connecting the top 25 collaborators of Willem P.C. Stemmer. A scholar is included among the top collaborators of Willem P.C. Stemmer based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Willem P.C. Stemmer. Willem P.C. Stemmer is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

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20 of 20 papers shown

Cleland, Jeffrey L., Jerome A. Moore, Benjamin Spink, et al.. (2012). A Novel Long-Acting Human Growth Hormone Fusion Protein (VRS-317): Enhanced In Vivo Potency and Half-Life. Journal of Pharmaceutical Sciences. 101(8). 2744–2754. 57 indexed citations

Alters, Susan E., Benjamin Spink, Chia‐Wei Wang, et al.. (2012). GLP2-2G-XTEN: A Pharmaceutical Protein with Improved Serum Half-Life and Efficacy in a Rat Crohn’s Disease Model. PLoS ONE. 7(11). e50630–e50630. 53 indexed citations

To, Wayne, Benjamin Spink, Michael D. Scholle, et al.. (2010). Gcg-XTEN: An Improved Glucagon Capable of Preventing Hypoglycemia without Increasing Baseline Blood Glucose. PLoS ONE. 5(4). e10175–e10175. 40 indexed citations

Schellenberger, Volker, Chia‐Wei Wang, Benjamin Spink, et al.. (2009). A recombinant polypeptide extends the in vivo half-life of peptides and proteins in a tunable manner. Nature Biotechnology. 27(12). 1186–1190. 340 indexed citations

Zhang, Yingxin, Kim Perry, Victor A. Vinci, et al.. (2002). Genome shuffling leads to rapid phenotypic improvement in bacteria. Nature. 415(6872). 644–646. 433 indexed citations

Keenan, Robert J. & Willem P.C. Stemmer. (2002). Nontransgenic crops from transgenic plants. Nature Biotechnology. 20(3). 215–216. 32 indexed citations

Patnaik, Ranjan, et al.. (2002). Genome shuffling of Lactobacillus for improved acid tolerance. Nature Biotechnology. 20(7). 707–712. 294 indexed citations

Krebber, Anke, Yonghong Chen, Jon E. Ness, et al.. (2001). Novel enzyme activities and functional plasticity revealed by recombining highly homologous enzymes. Chemistry & Biology. 8(9). 891–898. 79 indexed citations

Soong, Nay-Wei, Laurel Nomura, Katja Pekrun, et al.. (2000). Molecular breeding of viruses. Nature Genetics. 25(4). 436–439. 80 indexed citations

10.

Powell, Sharon K., Michele Kaloss, Michael Pensiero, et al.. (2000). Breeding of retroviruses by DNA shuffling for improved stability and processing yields. Nature Biotechnology. 18(12). 1279–1282. 71 indexed citations

11.

Chang, Chia-Chun, Brett Cox, Glenn Dawes, et al.. (1999). Evolution of a cytokine using DNA family shuffling. Nature Biotechnology. 17(8). 793–797. 104 indexed citations

12.

Ness, Jon E., Mark Welch, Lori Giver, et al.. (1999). DNA shuffling of subgenomic sequences of subtilisin. Nature Biotechnology. 17(9). 893–896. 143 indexed citations

13.

Crameri, Andreas, et al.. (1997). Molecular evolution of an arsenate detoxification pathway by DNA shuffling. Nature Biotechnology. 15(5). 436–438. 121 indexed citations

14.

Stemmer, Willem P.C., et al.. (1996). Affinity Selective Isolation of Ligands from Peptide Libraries Through Display on alacRepressor "Headpiece Dimer">. Journal of Molecular Biology. 255(3). 373–386. 28 indexed citations

15.

Crameri, Andreas, et al.. (1996). Construction and evolution of antibody–phage libraries by DMA shuffling. Nature Medicine. 2(1). 100–102. 75 indexed citations

16.

Stemmer, Willem P.C.. (1994). Rapid evolution of a protein in vitro by DNA shuffling. Nature. 370(6488). 389–391. 1432 indexed citations breakdown →

17.

Crameri, Andreas & Willem P.C. Stemmer. (1993). 10²⁰Fold aptamer library amplification without gel purification. Nucleic Acids Research. 21(18). 4410–4410. 31 indexed citations

18.

Stemmer, Willem P.C., et al.. (1993). Increased antibody expression from Escherichia coli through wobble-base library mutagenesis by enzymatic inverse PCR. Gene. 123(1). 1–7. 19 indexed citations

19.

Stemmer, Willem P.C.. (1991). A 20-minute ethidium bromide/high-salt extraction protocol for plasmid DNA.. PubMed. 10(6). 726–726. 28 indexed citations

20.

Stemmer, Willem P.C.. (1987). Fimbriae of Phytopathogenic and Symbiotic Bacteria. Phytopathology. 77(12). 1633–1633. 14 indexed citations

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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