Federico Cappuzzo

48.3k total citations · 14 hit papers
360 papers, 24.6k citations indexed

About

Federico Cappuzzo is a scholar working on Pulmonary and Respiratory Medicine, Oncology and Molecular Biology. According to data from OpenAlex, Federico Cappuzzo has authored 360 papers receiving a total of 24.6k indexed citations (citations by other indexed papers that have themselves been cited), including 288 papers in Pulmonary and Respiratory Medicine, 268 papers in Oncology and 66 papers in Molecular Biology. Recurrent topics in Federico Cappuzzo's work include Lung Cancer Treatments and Mutations (255 papers), Lung Cancer Research Studies (102 papers) and Colorectal Cancer Treatments and Studies (91 papers). Federico Cappuzzo is often cited by papers focused on Lung Cancer Treatments and Mutations (255 papers), Lung Cancer Research Studies (102 papers) and Colorectal Cancer Treatments and Studies (91 papers). Federico Cappuzzo collaborates with scholars based in Italy, United States and Germany. Federico Cappuzzo's co-authors include Tony Mok, Pasi A. Jänne, Lucio Crinò, Marileila Varella‐Garcia, Tarek Mekhail, Robert M. Jotte, Marcin Kowanetz, Luca Toschi, Stefania Bartolini and Fiona Blackhall and has published in prestigious journals such as Science, New England Journal of Medicine and Proceedings of the National Academy of Sciences.

In The Last Decade

Federico Cappuzzo

343 papers receiving 24.1k citations

Hit Papers

MET Amplification Leads to Gefitinib Resistance in Lung C... 2007 2026 2013 2019 2007 2018 2014 2019 2010 1000 2.0k 3.0k
What are hit papers?

Hit papers significantly outperform the citation benchmark for their cohort. A paper qualifies if it has ≥500 total citations, achieves ≥1.5× the top-1% citation threshold for papers in the same subfield and year (this is the minimum needed to enter the top 1%, not the average within it), or reaches the top citation threshold in at least one of its specific research topics.

  1. MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
    2007 3.6k citations Jeffrey A. Engelman, Kreshnik Zejnullahu et al. Science profile →
  2. Atezolizumab for First-Line Treatment of Metastatic Nonsquamous NSCLC
    2018 2.6k citations Mark A. Socinski, Federico Cappuzzo et al. profile →
  3. First-Line Crizotinib versus Chemotherapy in ALK-Positive Lung Cancer
    2014 2.3k citations Benjamin Solomon, Tony Mok et al. profile →
  4. Atezolizumab in combination with carboplatin plus nab-paclitaxel chemotherapy compared with chemotherapy alone as first-line treatment for metastatic non-squamous non-small-cell lung cancer (IMpower130): a multicentre, randomised, open-label, phase 3 trial
    2019 1.1k citations Alessandro Morabito, Tarek Mekhail et al. profile →
  5. Erlotinib as maintenance treatment in advanced non-small-cell lung cancer: a multicentre, randomised, placebo-controlled phase 3 study
    2010 917 citations Federico Cappuzzo et al. profile →
  6. Atezolizumab plus bevacizumab and chemotherapy in non-small-cell lung cancer (IMpower150): key subgroup analyses of patients with EGFR mutations or baseline liver metastases in a randomised, open-label phase 3 trial
    2019 688 citations Martin Reck, Tony Mok et al. profile →
  7. PD-1 and PD-L1 expression in molecularly selected non-small-cell lung cancer patients
    2014 492 citations Armida D’Incecco, Elisa Rossi et al. profile →
  8. Increased MET Gene Copy Number Negatively Affects Survival of Surgically Resected Non–Small-Cell Lung Cancer Patients
    2009 455 citations Federico Cappuzzo, Antonio Marchetti et al. Journal of Clinical Oncology profile →
  9. Atezolizumab in Combination With Carboplatin and Nab-Paclitaxel in Advanced Squamous NSCLC (IMpower131): Results From a Randomized Phase III Trial
    2020 405 citations Federico Cappuzzo, Mark A. Socinski et al. Journal of Thoracic Oncology profile →
  10. IMpower150 Final Overall Survival Analyses for Atezolizumab Plus Bevacizumab and Chemotherapy in First-Line Metastatic Nonsquamous NSCLC
    2021 316 citations Mark A. Socinski, Federico Cappuzzo et al. Journal of Thoracic Oncology profile →
  11. Final Overall Survival Analysis From a Study Comparing First-Line Crizotinib Versus Chemotherapy in ALK-Mutation-Positive Non–Small-Cell Lung Cancer
    2018 285 citations Benjamin Solomon, Yi‐Long Wu et al. Journal of Clinical Oncology profile →
  12. Targeting MET in Lung Cancer: Will Expectations Finally Be MET?
    2016 268 citations Federico Cappuzzo, D. Ross Camidge et al. Journal of Thoracic Oncology profile →
  13. New promises and challenges in the treatment of advanced non-small-cell lung cancer
    2024 116 citations Luis Paz‐Ares, Federico Cappuzzo et al. profile →
  14. Association of Immune-Related Adverse Events With Efficacy of Atezolizumab in Patients With Non–Small Cell Lung Cancer
    2023 102 citations Mark A. Socinski, Federico Cappuzzo et al. profile →

Peers

Federico Cappuzzo
Comparison fields: 5 of 148
  • Oncology 16.9k
  • Pulmonary and Respiratory Medicine 16.9k
  • Molecular Biology 7.0k
  • Cancer Research 4.3k
  • Pathology and Forensic Medicine 1.8k
Replace D. Ross Camidge with:
D. Ross Camidge United States
Giorgio V. Scagliotti Italy
Lesley Seymour Canada
Rafael Rosell Spain
Keunchil Park South Korea
Alan Sandler United States
Benjamin Solomon Australia
Neal I. Lindeman United States
Silvia Novello Italy
Mark A. Socinski United States
D. Ross Camidge United States View profile →
Citations per field, relative to Federico Cappuzzo
Federico Cappuzzo · 1×
Citations per year, relative to Federico Cappuzzo
Federico Cappuzzo · 1×

Countries citing papers authored by Federico Cappuzzo

Since Specialization
Citations

This map shows the geographic impact of Federico Cappuzzo's research. It shows the number of citations coming from papers published by authors working in each country. You can also color the map by specialization and compare the number of citations received by Federico Cappuzzo with the expected number of citations based on a country's size and research output (numbers larger than one mean the country cites Federico Cappuzzo more than expected).

Fields of papers citing papers by Federico Cappuzzo

Since Specialization
Physical SciencesHealth SciencesLife SciencesSocial Sciences

This network shows the impact of papers produced by Federico Cappuzzo. Nodes represent research fields, and links connect fields that are likely to share authors. Colored nodes show fields that tend to cite the papers produced by Federico Cappuzzo. The network helps show where Federico Cappuzzo may publish in the future.

Co-authorship network of co-authors of Federico Cappuzzo

This figure shows the co-authorship network connecting the top 25 collaborators of Federico Cappuzzo. A scholar is included among the top collaborators of Federico Cappuzzo based on the total number of citations received by their joint publications. Widths of edges represent the number of papers authors have co-authored together. Node borders signify the number of papers an author published with Federico Cappuzzo. Federico Cappuzzo is excluded from the visualization to improve readability, since they are connected to all nodes in the network.

All Works

20 of 20 papers shown
# Work Indexed citations
1
Antibody-Based Therapeutics in Small Cell Lung Cancer: A Narrative Review
2025 ·Biologics ·(unknown), (unknown), (unknown), (unknown), Lorenza Landi, Federico Cappuzzo
1
2
TP53 co-mutations increase risk of recurrence in EGFR-mutated stage I lung adenocarcinoma
2025 ·European Journal of Cancer ·Filippo Tommaso Gallina, Daniele Marinelli, (unknown), Paolo Visca, (unknown), Lorenza Landi, Simonetta Buglioni, (unknown), Enrico Melis, Sara Najmeh, Roni Rayes, Jonathan Cools‐Lartigue, Sophie Camilleri‐Broët, Pierre Fiset, Lorenzo Ferri, Federico Cappuzzo, Jonathan Spicer
0
3
Circulating tumour DNA in early stage and locally advanced NSCLC: ready for clinical implementation?
2025 ·Nature Reviews Clinical Oncology ·Nicola Normanno, Alessandro Morabito, Anna Maria Rachiglio, Vincenzo Sforza, Lorenza Landi, Emilio Bria, Angelo Delmonte, Federico Cappuzzo, Antonella De Luca
7
4
First-Line Sacituzumab Govitecan Plus Pembrolizumab in Metastatic NSCLC: PD-L1 TPS Less Than 50% and More Than or Equal to 50% Cohorts of the EVOKE-02 Study
2025 ·Journal of Thoracic Oncology ·Martin Reck, Jyoti D. Patel, Jhanelle E. Gray, Noemı́ Reguart, Manuel Cobo, José Fuentes Pradera, Enriqueta Felip, Federico Cappuzzo, Edward B. Garon, Joel W. Neal, Sabeen Mekan, (unknown), (unknown), Marianna Zavodovskaya, Juliane M. Jürgensmeier, Michael Chisamore, Byoung Chul Cho
0
5
Acasunlimab (DuoBody-PD-L1x4-1BB) alone or in combination with pembrolizumab (pembro) in patients (pts) with previously treated metastatic non-small cell lung cancer (mNSCLC): Initial results of a randomized, open-label, phase 2 trial.
2024 ·Journal of Clinical Oncology ·Joachim G.J.V. Aerts, Luis Paz‐Ares, Carole Hélissey, Federico Cappuzzo, Gilles Quéré, Dariusz M. Kowalski, José Carlos Benítez, Florian Guisier, Benjamin Besse, Shirish M. Gadgeel, Thomas Wehler, Ignacio Gil‐Bazo, Michael Chisamore, Cem Z. Görgün, Ilhan Celik, (unknown), Patricia Garrido Castro, Teng Jin Ong, Enriqueta Felip
6
6
KontRASt-02: A phase III trial investigating the efficacy and safety of the KRAS G12C inhibitor JDQ443 vs docetaxel in patients with previously treated, locally advanced or metastatic, KRAS G12C -mutated NSCLC.
2023 ·Journal of Clinical Oncology ·Federico Cappuzzo, Gilberto de Castro, Jin‐Hyoung Kang, Yi‐Long Wu, Odd Terje Brustugun, Parneet Cheema, Taofeek K. Owonikoko, (unknown), Aislyn Boran, (unknown), (unknown), Herbert H. Loong
8
7
Poziotinib in Treatment-Naive NSCLC Harboring HER2 Exon 20 Mutations: ZENITH20-4, A Multicenter, Multicohort, Open-Label, Phase 2 Trial (Cohort 4)
2023 ·Journal of Thoracic Oncology ·Robin Cornelissen, Arsela Prelaj, Sophie Sun, Christina S. Baik, Mirjana Wollner, Eric B. Haura, Hirva Mamdani, Jonathan W. Riess, Federico Cappuzzo, Marina Chiara Garassino, John V. Heymach, Mark A. Socinski, Szu‐Yun Leu, Gajanan Bhat, François Lebel, Xiuning Le
34
8
Low Risk of Hyperprogression with First-Line Chemoimmunotherapy for Advanced Non-Small Cell Lung Cancer: Pooled Analysis of 7 Clinical Trials
2023 ·The Oncologist ·(unknown), Federico Cappuzzo, Ignacio Matos, Mark A. Socinski, Ashley M. Hopkins, Michael J. Sorich
7
9
Compromised Outcomes in Stage IV Non–Small-Cell Lung Cancer With Actionable Mutations Initially Treated Without Tyrosine Kinase Inhibitors: A Retrospective Analysis of Real-World Data
2023 ·JCO Oncology Practice ·Jeffrey A. Scott, Jochen K. Lennerz, Melissa L. Johnson, Lucio Gordan, (unknown), Luca Quagliata, Lauren L. Ritterhouse, Federico Cappuzzo, Brandon Wang, Mei Xue, Anupama Vasudevan, (unknown), Varun Vaidya, (unknown), (unknown), Hinco J. Gierman, (unknown)
28
10
Analysis of Molecular Biomarkers in Resected Early-Stage Non-Small Cells Lung Cancer: A Narrative Review
2022 ·Cancers ·Filippo Tommaso Gallina, Luca Bertolaccini, (unknown), Shehab Mohamed, (unknown), Enrico Melis, (unknown), (unknown), Daniele Marinelli, Simonetta Buglioni, Paolo Visca, Federico Cappuzzo, Lorenzo Spaggiari, Francesco Facciolo
6
11
Not enough can be enough: feasibility of the Idylla EGFR mutation test when reuse of stained tissue slides is the only option available
2021 ·Journal of Clinical Pathology ·Cristiana Ercolani, Anna Di Benedetto, (unknown), Paolo Visca, (unknown), (unknown), (unknown), Irene Terrenato, Edoardo Pescarmona, Gennaro Ciliberto, Fabiana Letizia Cecere, Federico Cappuzzo, Simonetta Buglioni
2
12
Worldwide Prevalence of Epidermal Growth Factor Receptor Mutations in Non-Small Cell Lung Cancer: A Meta-Analysis
2021 ·Molecular Diagnosis & Therapy ·Barbara Melosky, Kato Kambartel, Maik Häntschel, M Bennetts, Dana J. Nickens, Julia Brinkmann, Antonin Kayser, Michael Moran, Federico Cappuzzo
124
13
Intracranial efficacy of first-line crizotinib vs. chemotherapy in ALK-positive NSCLC
2015 ·Journal of Thoracic Oncology ·Benjamin Solomon, Federico Cappuzzo, Enriqueta Felip, Fiona Blackhall, (unknown), (unknown), Kunitoshi Nakagawa, Yue Wu, Tarek Mekhail, Jolanda Paolini, Jennifer Tursi, Tiziana Usari, K. Wilner, Paulina Selaru, Tony Mok
1
14
Lung cancer patients with HER2 mutations treated with chemotherapy and HER2-targeted drugs: results from the European EUHER2 cohort
2015 ·Annals of Oncology ·Julien Mazières, Fabrice Barlési, Thomas Filleron, Benjamin Besse, I. Monnet, Michèle Beau‐Faller, Solange Peters, Éric Dansin, Martin Früh, Miklos Pless, Rafael Rosell, Marie Wislez, P. Fournel, Virginie Westeel, Federico Cappuzzo, Alexis B. Cortot, Denis Moro‐Sibilot, Julie Milia, Oliver Gautschi
219
15
Phase II Study of Afatinib, an Irreversible ErbB Family Blocker, in EGFR FISH-Positive Non–Small-Cell Lung Cancer
2014 ·Journal of Thoracic Oncology ·Federico Cappuzzo, Giovanna Finocchiaro, Francesco Grossi, Paolo Bidoli, Adolfo Favaretto, Antonio Marchetti, Marialuisa Valente, A. Cseh, (unknown), Dan Massey, Armando Santoro
22
16
Targeted therapy for NSCLC with driver mutations
2013 ·Expert Opinion on Biological Therapy ·Gabriele Minuti, Armida D’Incecco, Federico Cappuzzo
38
17
Identifying and Targeting ROS1 Gene Fusions in Non–Small Cell Lung Cancer
2012 ·Clinical Cancer Research ·Kurtis D. Davies, Anh T. Le, Mariana F. Theodoro, Margaret C. Skokan, Dara L. Aisner, Eamon M. Berge, Luigi Terracciano, Federico Cappuzzo, Matteo Incarbone, Massimo Roncalli, Marco Alloisio, Armando Santoro, D. Ross Camidge, Marileila Varella‐Garcia, Robert C. Doebele
330
18
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling breakdown →
2007 ·Science ·Jeffrey A. Engelman, Kreshnik Zejnullahu, Tetsuya Mitsudomi, Youngchul Song, Courtney Hyland, Joon Oh Park, Neal I. Lindeman, (unknown), Xiao‐Jun Zhao, James G. Christensen, Takayuki Kosaka, Alison J. Holmes, Andrew M. Rogers, Federico Cappuzzo, Tony Mok, Charles Lee, Bruce E. Johnson, Lewis C. Cantley, Pasi A. Jänne
3570
19
Prospective Study of Gefitinib in Epidermal Growth Factor Receptor Fluorescence In Situ Hybridization–Positive/Phospho-Akt–Positive or Never Smoker Patients With Advanced Non–Small-Cell Lung Cancer: The ONCOBELL Trial
2007 ·Journal of Clinical Oncology ·Federico Cappuzzo, Claudia Ligorio, Pasi A. Jänne, Luca Toschi, Elisa Rossi, Rocco Trisolini, Daniela Paioli, Alison J. Holmes, Elisabetta Magrini, Giovanna Finocchiaro, Stefania Bartolini, Alessandra Cancellieri, Fortunato Ciardiello, Marco Patelli, Lucio Crinò, Marileila Varella‐Garcia
174
20
Gefitinib in Pretreated Non–Small-Cell Lung Cancer (NSCLC): Analysis of Efficacy and Correlation With HER2 and Epidermal Growth Factor Receptor Expression in Locally Advanced or Metastatic NSCLC
2003 ·Journal of Clinical Oncology ·Federico Cappuzzo, Vanesa Gregorc, Elisa Rossi, Alessandra Cancellieri, Elisabetta Magrini, Carlo Paties, Giovanni Luca Ceresoli, Laura Lombardo, Stefania Bartolini, C. Calandri, Marisa De Rosa, Eugenio Villa, Lucio Crinò
175

Rankless uses publication and citation data sourced from OpenAlex, an open and comprehensive bibliographic database. While OpenAlex provides broad and valuable coverage of the global research landscape, it—like all bibliographic datasets—has inherent limitations. These include incomplete records, variations in author disambiguation, differences in journal indexing, and delays in data updates. As a result, some metrics and network relationships displayed in Rankless may not fully capture the entirety of a scholar's output or impact.

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